Clinical trials: Post Cardiac Surgery
Delirium
The Study of Post-operation Delirium and Prognosis of Cardiac Surgery Patients
Delirium is the most common neurological complication of cardiac surgery patients and associated with poor prognosis. In recent years, the important role of quantitative electroencephalogram (qEEG) in brain function monitoring is…
- Trial name
- NCT03351985
- Testing
- quantitative electroencephalogram (qEEG)
- Volunteers
- 56 people
- Sponsor
- Southeast University, China
Pneumothorax, Cardiac Surgery
Nurse-performed Lung Ultrasound Versus Chest Radiography for Detection of Pneumothorax.
This is a prospective, single-center, observational, cross-sectional cohort study, comparing nurse-performed bedside lung ultrasound to standard portable CXR, for the detection of pneumothorax in the cardiac surgery patient…
- Trial name
- NCT04678726
- Testing
- Lung ultrasound assessment for ruling out pneumothorax
- Sponsor
- University Health Network, Toronto
Pain, Postoperative
Gabapentin for Postoperative Pain Management After Cardiac Surgery With Median Sternotomy
In this study we will focus on the postoperative recovery. A successful postoperative recovery should bring the patient to at least to the pre-surgical level.
- Trial name
- NCT00572208
- Testing
- Gabapentin group
- Where
- 2 sites in Denmark
- Volunteers
- 64 people
- Sponsor
- Aarhus University Hospital
Vasoplegic Syndrome, Vasoplegia
Analysis of miRNAs Expression in Vasoplegic Syndrome After On-pump Coronary Artery Bypass Surgery
This study looks for a correlation between microRNAs (miRNAs) and vasoplegic syndrome after on-pump coronary artery bypass surgery.
- Conditions
- Vasoplegic Syndrome, Vasoplegia, Surgery-Complications, Surgery
- Trial name
- PREVENT (NCT05354193)
- Testing
- vasoplegic syndrome
- Where
- Brazil
- Volunteers
- 320 people
- Sponsor
- University of Sao Paulo General Hospital
After Cardiac Surgery, Diuretic Resistance
Evaluation of the Efficacy of rhBNP in Patients With Diuretic Resistance After Cardiac Surgery
evaluation of the efficacy of recombinant human brain natriuretic peptide in patients with diuretic resistance after cardiac surgery: a prospective single-center single-blind randomized controlled study
- Trial name
- rhBNP (NCT07086287)
- Testing
- rhBNP and standard basic treatment
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Acute Kidney Injury
Preop Digifab in CABG to Reduce Ouabain Levels and Prevent AKI
Acute kidney injury (AKI) occurs in up to 30% of patients undergoing coronary artery bypass graft (CABG) surgery, and often requires patients to go on dialysis.
- Trial name
- NCT03810417
- Testing
- Digoxin Antibodies Fab Fragments, Baseline EO > 360 pM, EO < 360 pM
- Where
- 2 sites in United States
- Volunteers
- 267 people
- Sponsor
- University of Maryland, Baltimore
Pediatric Heart Failure, Congenital Heart Disease (CHD)
MedlyPeds Feasibility Study
SickKids and UHN have developed MedlyPeds which is a smart phone application designed to remotely monitor patients with heart disease.
- Conditions
- Pediatric Heart Failure, Congenital Heart Disease (CHD), Acquired Heart Disease, Pulmonary Hypertension
- Trial name
- NCT07556185
- Testing
- MedlyPeds App
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- The Hospital for Sick Children
Congenital Heart Disease
HFNC vs NIPPV Following Extubation
This study has the goal to determine the best method of respiratory support following extubation after cardiac surgery (CS). After cardiac surgery for Congenital Heart Disease (CHD), patients remain intubated until the cardiac…
- Trial name
- NCT05869825
- Testing
- High Flow Nasal Canula following extubation, Non-Invasive Positive Pressure Ventilation following extubation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Emory University
Open Heart Surgery
Sternal Closure in Children After Cardiac Surgery
comparison between stainless steel wires and PDS in closure of sternum in children after cardiac surgery in terms of sternal dehiscence, infection \& cosmetic outcome
- Trial name
- NCT05715060
- Testing
- Median sternotomy closure (sternal closure)
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Assiut University
Myocardial Injury After Noncardiac Surgery (MINS)
Myocardial Injury After Transurethral Resection
This prospective observational study aims to determine the incidence of myocardial injury after noncardiac surgery (MINS) in adult patients undergoing elective transurethral resection of the prostate (TURP) or transurethral…
- Trial name
- TUR-MINS (NCT07900035)
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people
- Sponsor
- Haseki Training and Research Hospital
Heart Failure, Vasoplegia
Prevention of Low Blood Pressure After Cardiac Surgery in Heart Failure Patients With a Filter Called CytoSorb.
Vasoplegia is a common complication after heart surgery for heart failure. With vasoplegia, the blood vessels can no longer squeeze properly, causing low blood pressure that is sometimes difficult to treat with medication.
- Trial name
- CytoSorb-HF (NCT04812717)
- Testing
- CytoSorb device
- Where
- Netherlands
- Volunteers
- 36 people
- Sponsor
- Leiden University Medical Center
Myocard Injury After Non Cardiac Surgery, Robotic Assisted Laparoscopic Radical Prostatectomy
PERIOPERATIVE MYOCARDIAL DAMAGE IN ROBOT-ASSISTED SURGERY
Our study aimed to identify myocardial damage during or after robotic-assisted radical prostatectomy by measuring high-sensitive Troponin I levels, which are the most sensitive and effective according to the AHA/ACC guideline.
- Trial name
- NCT06502340
- Testing
- high sensitive troponin I
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Pulmonary Complications
Effectiveness Of Modified Chest PT Technidue In Pre And Post-Operative Program In Patients Open Heart Surgery
The purpose of this study is to explore effectiveness of modified chest physical therapy techniques using new device in pre and post-operative program in patients undergoing open heart surgery
- Trial name
- NCT02894879
- Testing
- BreatheMAX®, Routine treatment
- Where
- Thailand
- Volunteers
- 48 people
- Sponsor
- Khon Kaen University
Cardiac Surgery, Dyspnea
Respiratory Physiotherapy and PMR After Cardiac Surgery
This study aims to evaluate the effects of respiratory physiotherapy combined with progressive muscle relaxation exercises on dyspnea, anxiety, hemodynamic status, and delirium symptoms in patients after cardiac surgery.
- Conditions
- Cardiac Surgery, Dyspnea, Anxiety, Delirium
- Trial name
- RESP-PMR (NCT07542691)
- Testing
- Respiratory Physiotherapy, Progressive Muscle Relaxation, Routine Care
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people
- Sponsor
- Istanbul Aydın University
Cardiac Disease
Predicting Cerebrovascular Adverse Events Post Cardiac Surgery
The aims of this study are: i) to assess cerebral autoregulation and autonomic control within the different phases of cardiac surgery with cardiopulmonary bypass; ii) to compare cerebral autoregulation measures derived via…
- Trial name
- PASCAL (NCT05786274)
- Testing
- Cerebral autoregulation monitoring
- Where
- Italy
- Volunteers
- 104 people
- Sponsor
- IRCCS Policlinico S. Donato
Coronary Artery Disease, Depression
Enhancing Recovery After Cardiac Surgery
Patients recovering from coronary artery bypass graft (CABG) surgery have high rates of depression, and depression is associated with higher risk of complications and death.
- Trial name
- NCT00522717
- Testing
- Cognitive Behavioral Therapy (CBT), Usual Care
- Where
- 5 sites in United States
- Volunteers
- 808 people
- Sponsor
- University of California, Los Angeles
Heart; Dysfunction Postoperative, Cardiac Surgery
Suppression Of Atrial Fibrillation With Ranolazine After Cardiac Surgery
The objective of this study is to show that ranolazine is a safe, viable and potent alternative for post-operative atrial fibrillation suppression in patients undergoing cardiac surgery
- Trial name
- NCT01352416
- Testing
- Ranolazine
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Corewell Health East
Acute Kidney Injury
Preoperative Level of Hemoglobin A1c and Acute Kindey Injury After Coronary Artery Bypass Grafting Surgery
Background: The development of acute kidney injury (AKI) is an important indicator of clinical outcomes after cardiac surgery. Elevated preoperative hemoglobin A1c level may be associated with acute kidney injury in patients…
- Trial name
- NCT05390281
- Testing
- increase in serum creatinine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Cardiac Anaesthesia, Cardiopulmonary Bypass
Comparison of Milrinone and Epinephrine on TAPSE
Cardiopulmonary bypass (CPB) is a critical technology in cardiac surgery, allowing for the temporary replacement of the heart and lung functions during intricate surgical procedures.
- Trial name
- Milrinone (NCT07144267)
- Testing
- Epinephrine, Milrinone Injection
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Mansoura University
Hypoxemic Acute Respiratory Failure
High Flow Nasal Oxygen Therapy for Hypoxemy After Cardiac Surgery
The main objective of this study is to evaluate the gas exchange (ventilation-perfusion ratio) with the system Optiflow® compared to facial mask among patients having an acute respiratory failure after cardiac surgery.
- Trial name
- Optiflow (NCT01617252)
- Testing
- Optiflow / Facial mask
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Nantes University Hospital