Clinical trials: Portal Hypertension
Liver Diseases, Liver Transplantation
Hepatic and Systemic Hemodynamic Modeling During Liver Surgery
" Despite the medical and surgical progress of the last two decades, the selection of candidates for liver surgery remains based on old principles and insufficiently sensitive to fine-tune the gesture to patient-specific…
- Trial name
- LSM (NCT05339984)
- Testing
- Partial hepatectomy (open approach), liver transplantation, Portal vein embolization
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Portal Hypertension, Liver Diseases
Achieving Portal Access With Scorpion Post-Approval Study 2
Creation of the parenchymal tract between the portal vein and the hepatic vein is the most difficult and time consuming step in a TIPS procedure.
- Conditions
- Portal Hypertension, Liver Diseases, Ascites Hepatic, Hydrothorax
- Trial name
- APASS2 (NCT06856655)
- Testing
- Scorpion Portal Vein Access Kit
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Argon Medical Devices
Colon Polyp, Colon Disease
Endoscopy-related Phone Consultation During the COVID-19 Outbreak
The aim of this study is to evaluate patient and consultant experiences with phone consultations for endoscopy-related outpatient appointments during the COVID-19 outbreak.
- Conditions
- Colon Polyp, Colon Disease, Reflux, Gastroesophageal, Varices, Esophageal
- Trial name
- NCT04344964
- Testing
- None - NA
- Where
- Australia
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Austin Health
Liver Cirrhosis
Long-term Efficacy and Safety of LSD Versus TIPS for Cirrhotic Portal Hypertension Bleeding and Hypersplenism
This study aims to compare two treatments for cirrhotic portal hypertension with acute esophagogastric variceal bleeding and hypersplenism: laparoscopic splenectomy and azygoportal disconnection (LSD) and transjugular…
- Trial name
- LSD、TIPS (NCT07490405)
- Testing
- LSD, TIPS
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Northern Jiangsu People's Hospital
Biliary Atresia, Alagille Syndrome
FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE)
Noninvasive monitoring of liver fibrosis is an unmet need within the clinical management of pediatric chronic liver disease. While liver biopsy is often used in the initial diagnostic evaluation, subsequent biopsies are rarely…
- Conditions
- Biliary Atresia, Alagille Syndrome, Alpha1 Anti-Trypsin Deficiency, Portal Hypertension
- Trial name
- FORCE (NCT02922751)
- Testing
- Liver Stiffness Measurement (LSM)
- Where
- 13 sites in United States, Canada
- Volunteers
- 552 people
- Sponsor
- Arbor Research Collaborative for Health
Portal Hypertension, Complications of Cirrhosis
Treatment for Prevention of Variceal Rebleeding Guided by the Hemodynamic Response
This is a prospective trial of random distribution, open, parallel group, in which patients with esophagic variceal bleeding will be randomized into two treatment groups, after controlling acute bleeding.
- Trial name
- NCT00563602
- Testing
- Hemodynamic guided therapy
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Advanced Chronic Liver Disease
LSM and SSM for the Diagnosis of CSPH: a Prospective Cohort Study
The goal of this observational study is to assess non-invasive tools' efficacy in predicting portal hypertension-related complications in individuals with advanced chronic liver disease.
- Trial name
- NCT06181409
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Cirrhosis, Liver
Intestinal Permeability in Patients With Liver Cirrhosis Using Confocal Endoscopy
The CEDIP LCI study is intended to show the difference in intestinal permeability between compensated and decompensated liver cirrhosis by confocal endoscopy.
- Trial name
- CEDIP-LCI (NCT03658551)
- Testing
- Fluorescein
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Johannes Gutenberg University Mainz
Portal Vein Thrombosis, Cirrhosis
Indicators Affecting PVT Recanalization
This is a retrospective-prospective study conducted at Zhongshan Hospital, Fudan University, to explore portal vein thrombosis (PVT) in patients with cirrhosis and gastroesophageal varices (GEV).
- Conditions
- Portal Vein Thrombosis, Cirrhosis, Portal Hypertension Related to Cirrhosis, Portal Hypertension, Noncirrhotic
- Trial name
- NCT07473375
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Shanghai Zhongshan Hospital
Ascites, Liver Cirrhosis
Proximal Splenic Artery Embolization (PSAE) for the Treatment of Refractory Ascites in Decompensated Cirrhosis
The purpose of this study is to learn whether a procedure called Proximal Splenic Artery Embolization (PSAE) can lower the need for repeat fluid drainage in adults with cirrhosis and a buildup of fluid in the abdomen (ascites)…
- Conditions
- Ascites, Liver Cirrhosis, Hypertension, Portal
- Trial name
- NCT07755059
- Testing
- Proximal Splenic Artery Embolization
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital