Clinical trials: Polypropylene
Hernia, Inguinal
Prospective Randomized Trial Comparing Lichtenstein's Repair of Inguinal Hernia With Polypropylene Mesh Versus Surgisis
To evaluate the safety and efficacy of the Lichtenstein's hernioplasty using the Surgisis ES soft tissue graft, as a mesh, and to compare it with the traditional Lichtenstein procedure performed with polypropylene mesh.
- Trial name
- NCT00614419
- Testing
- Prolene Polypropylene Mesh, Surgisis Inguinal Hernia Matrix
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Vocal Cord Paralysis, Phonasthenia
A Novel Approach for Thyroplasty Type 1, With Prolene Mesh. A Prospective Study.
Larynx performs important functions of the aero-digestive tract, it has vital role in control of breathing, phonation, deglutition and protection of lower respiratory tract from aspiration.
- Conditions
- Vocal Cord Paralysis, Phonasthenia, Presbylarynges, Idiopathic Vocal Cord Paralysis
- Trial name
- NCT04458818
- Testing
- Prolene Mesh Vocal Cord Medialization Implant
- Where
- Pakistan
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Muhammad Rashid
Umbilical Hernia
Self-Expanding Multi-Layered Partially Resorbable Lightweight Polypropylene Mesh Device (Proceed Ventral Patch® Or Pvp®) For The Treatment of Small and Medium Umbilical Ventral Hernias
Meshes-devices using dual-sided mesh technology have been developed for the specific indication of small ventral hernias. The design of these meshes allows introduction of a mesh of appropriate size to cover the hernia defect…
- Trial name
- NCT01307696
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Pelvic Organ Prolapse
Safety Study of Pelvic Organ Prolapse Repair Using Transvaginal Mesh
Pelvic organ prolapse is characterized by a lack of pelvic floor support causing the pelvic organs and vaginal walls to protrude.
- Trial name
- NCT00402844
- Testing
- Transvaginal mesh- PROLIFT®-system
- Where
- 26 sites in Denmark, Finland and 2 more
- Volunteers
- 250 people
- Sponsor
- Karolinska Institutet
Pelvic Organ Prolapse
Long-term Success Rate of Transvaginal Mesh for the Treatment of Pelvic Organ Prolapse: The Extended RCT Study
The original RCT trial is designed to compare self-tailored titanium-coated polypropylene mesh procedure with mesh-kit in the treatment of POP stage III-IV in terms of efficacy, safety and cost-effective at 1-year follow-up.
- Trial name
- NCT05938881
- Testing
- self-cut mesh procedure, mesh-kit procedure
- Where
- 11 sites in China
- Volunteers
- 336 people
- Sponsor
- Peking Union Medical College Hospital
Hernia, Cystocele
Surgical Treatment To Greater Anterior Vaginal Prolapse
A RCT study to compare traditional colporrhaphy versus polypropylene mesh in treatment of the anterior vaginal wall prolapse.
- Trial name
- Nazcatc™ (NCT00676325)
- Testing
- Surgical treatment of Anterior Vaginal Prolapse, NAZCA TC™ POP REPAIR SYSTEM ,promedon® , argentina., surgical treatment for anterior vaginal wall prolapse
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Alveolar Socket Preservation, Bone Regeneration
Effects of Simvastatin Gel on Bone Neoformation in Post-extraction Sockets: a Randomized Controlled Trial
Statins (HMG-CoA) are widely used in treating patients with hypercholesterolemia. They have also been studied because of their anabolic effects on bone tissue.
- Trial name
- NCT04149080
- Testing
- SIM + polypropylene membrane
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Ventral Hernia, Incisional Hernia
Titanium vs Absorbable Tacks for Mesh Fixation in Laparoscopic Incisional and Ventral Hernia Repair
Background: Laparoscopic repair of ventral hernias has gained popularity, since many studies and a recent meta-analysis have reported encouraging results and recurrence rates similar to open repair.
- Trial name
- NCT02076984
- Testing
- Laparoscopic incisional or ventral hernia repair
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Roma La Sapienza
Rectal Prolapse, Pelvic Organ Prolapse (POP)
RECTOSACROUTEROPEXY vs. WELLS
The goal of this clinical trial was to compare two surgical techniques in female patients with full-thickness rectal prolapse. The main questions it aimed to answer were: 1.
- Trial name
- RSUP (NCT07673406)
- Testing
- Modified rectosacrouteropexy, Wells rectopexy
- Where
- Azerbaijan
- Volunteers
- 36 people
- Sponsor
- Azerbaijan Medical University
Chronic Pain
Lichtenstein Patch or Prolene Hernia System (PHS) for Inguinal Hernia Repair
This randomised prospective study was designed to compare the convalescence and the long-term sequelae in inguinal hernia repair with either a bilayer mesh as devised by Gilbert (Prolene Hernia System®) or an onlay mesh applied…
- Trial name
- NCT01070693
- Testing
- Open mesh inguinal hernia repair, Prolene Hernia System, Lichtenstein technique
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Helsinki University Central Hospital
Pelvic Organ Prolapse
Randomized,Multicentric Study to Treat Prolapse After Hysterectomy With Amreich Procedure or Total Prolift Procedure
Head to Head comparison of perioperative complications and secondary the impact of operation techniques with or without mesh on patients suffering from pelvic organ prolapse on quality of life.
- Trial name
- NCT00572702
- Testing
- Vaginal fixation Amreich-Richter, Prolift total
- Where
- 5 sites in Czechia
- Volunteers
- 200 people
- Sponsor
- Charles University, Czech Republic
Hernia, Inguinal
Efficacy of Macroporous Polytetrafluoroethylene Mesh in Laparoscopic Hernia Repair
Inguinal hernia repair is one of the most commonly performed surgeries around the world. It accounts for approximately 75% of all abdominal wall hernias and presents a lifetime risk of 27% in males and 3% in females.
- Trial name
- PTFE (NCT02023203)
- Testing
- Totally Extraperitoneal laparoscopic inguinal hernia repair
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Scar
Impact of Suture Type on Pigment Disturbances in Patients of Skin of Color
The present study assesses if dissolvable (fast gut) or non-dissolvable (polypropylene) epidermal sutures produce better cosmetic results in terms of dyspigmentation and scarring in patients of skin of color.
- Trial name
- NCT05408117
- Testing
- 5-0 Polypropylene epidermal suture, 5-0 Fast gut epidermal suture
- Where
- 3 sites in United States
- Volunteers
- 34 people
- Sponsor
- Melissa Pugliano-Mauro
İnguinal Hernia, Complication,Postoperative
Post-Surgical Outcomes of Conventional vs 3-Point Mesh Fixation in Lichtenstein Repair: An RCT
This is a single-center, parallel-group randomized controlled trial conducted in 2025-2025 at the General Surgery Ward of the Sindh Institute of Urology and Transplantation (SIUT), Karachi.
- Conditions
- İnguinal Hernia, Complication,Postoperative, Pain, Postoperative
- Trial name
- COMET (NCT07334548)
- Testing
- 3-point mesh fixation, Conventional Mesh Fixation
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Sahar Mughis
Cystocele, Uterine Prolapse
Anterior Pelvic Prolapse Reconstruction With TiLOOP® Total 6
The purpose of this study is to determine the influence of Anterior Pelvic Prolapse Reconstruction with a titanised polypropylene mesh on rate of erosion and patients quality of live.
- Trial name
- NCT01084889
- Testing
- surgical mesh implantation (TiLOOP® Total 6)
- Where
- 9 sites in Germany
- Volunteers
- 292 people
- Sponsor
- pfm medical gmbh