Clinical trials: Polyp
Chronic Rhinosinusitis With Nasal Polyps
Tapering of Biologics in Chronic Rhinosinusitis With Nasal Polyps
The purpose of this study is to investigate the feasibility of extending the dosing intervals of biological therapies while maintaining optimal treatment effects in chronic rhinosinusitis with nasal polyps (CRSwNP).
- Trial name
- NCT07187583
- Testing
- increased dosing interval of biological therapy
- Where
- 9 sites in Denmark
- Volunteers
- 135 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Colorectal Cancer, Polyps
Aspirin/Folate Prevention of Large Bowel Polyps
This is a randomized controlled trial of aspirin and/or folate supplementation for the prevention of the recurrence of neoplastic polyps (adenomas) of the large bowel.
- Conditions
- Colorectal Cancer, Polyps, Adenomas
- Trial name
- NCT00272324
- Testing
- Aspirin, Folate
- Where
- 9 sites in United States, Canada
- Volunteers
- 1,121 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Neoplasms, Colorectal
Green Tea Extracts for the Prevention of Colorectal Adenomas and Colorectal Cancer
Experimental studies have shown the chemopreventive properties of green tea extract (GTE) on colorectal cancer. And colorectal adenomas are precursors to colorectal cancers.
- Trial name
- NCT02321969
- Testing
- GTE (green tea extract)
- Volunteers
- 176 people
- Sponsor
- Seoul National University Hospital
Asthma, Chronic Rhinosinusitis With Nasal Polyps
Opening the "Black Box" on Tezepelumab's Effect on Chronic Rhinosinusitis With Severe Asthma
The study explores how chronic rhinosinusitis (CRS) and asthma share a common inflammatory process, particularly affecting patients with both conditions.
- Trial name
- NCT06740045
- Testing
- Tezepelumab
- Volunteers
- 10 people
- Sponsor
- Dr. Andrew Thamboo, MD
Acute Recurrent Rhinosinusitis
Cleaning of the Nose After Sinus Surgery: Necessary or Only Bothersome?
The goal of this study is to increase knowledge about how to treat patients after sinus surgery.
- Trial name
- NCT00184392
- Testing
- debridement or saline irrigation
- Where
- 2 sites in Norway
- Volunteers
- 60 people
- Sponsor
- Norwegian University of Science and Technology
Polyp of Colon
Pronostic Score of Morbidity to Determine Risk of Complications After Endoscopic Submucosal Dissection for Colorectal Lesions
The mains complications in colo-rectal dissection are the pain, the delayed bleeding and the perforation and represent around 10%.
- Trial name
- NCT04647266
- Testing
- endoscopic submucosal dissection
- Where
- France
- Volunteers
- 168 people
- Sponsor
- Central Hospital, Nancy, France
Appendicitis, Evidence of Cholecystectomy
Point of Care 3D Ultrasound for Various Applications: A Pilot Study
Summary 1. Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound in obtaining abdominal and/or pelvic images.
- Conditions
- Appendicitis, Evidence of Cholecystectomy, Gallstones, Pregnancy, Ectopic
- Trial name
- NCT02831556
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Duke University
Chronic Rhinosinusitis
Rhinosinusitis Italian Network: the Italian Registry for Severe, Uncontrolled Chronic Rhinosinusitis
This observatory aims to collect, as widely as possible, the Italian cases of patients with uncontrolled CRS. Patient will be enrolled by the centers of the Italian Network of Rhinosinusitis (Rhinosinusitis Italian Network…
- Trial name
- RINET (NCT05935683)
- Testing
- Severe Uncontrolled Chronic Rhinosinusitis patients (CRS)
- Where
- Italy
- Volunteers
- 5,000 people
- Sponsor
- Italian Academy of Rhinology
Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum
Anterior Ethmoidal Nerve Block in Prevention of Postoperative Agitation
Postoperative agitation is an important complication of general anesthesia, moreover, it has been found with high incidence in ear, nose, throat (ENT) surgeries.
- Conditions
- Postoperative Agitation: Impaired Awareness, Abnormal Cognitive Function, Confusion, and Verbal and Physical Agitation During Recovery From General Anesthesia, Deviated Nasal Septum, Chronic Rhinosinusitis (Diagnosis), Nasal Polyps
- Trial name
- NCT03427502
- Testing
- Bupivacaine-epinephrine, normal saline
- Where
- Nepal
- Volunteers
- 100 people
- Sponsor
- Lumbini Medical College
Colonic Polyp, Colorectal Cancer
Study on Second Forward View Examination in the Right Colon
It is estimated that there are about 1.4 million patients with colorectal cancer (CRC) worldwide, with a rising trend in CRC incidence in many Asian Pacific countries.
- Trial name
- NCT03121495
- Testing
- Second forward view (SFV) examination of the right colon
- Where
- 3 sites in Hong Kong
- Volunteers
- 1,011 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Pedunculated Colorectal Polyp
UEMR Versus HSP in the Treatment of Pedunculated Colorectal Polyps Less Than 10mm in Size
A prospective, single-center, open-label, randomized controlled study to compare the effectiveness and safety of underwater endoscopic mucosal resection (UEMR) and hot snare polypectomy (HSP) in treating Pedunculated colorectal…
- Trial name
- NCT06996522
- Testing
- underwater endoscopic mucosal resection, Hot snare polypectomy
- Where
- China
- Volunteers
- 338 people
- Sponsor
- Fudan University
Polyp of Colon
Clinical vAliDation of ARTificial Intelligence in POlyp Detection
This study is an open label, unblinded, non-randomized interventional study, comparing the investigational artificial intelligence tool with the current "gold standard": Data acquisition will be obtained during one scheduled…
- Trial name
- CAD-ARTIPOD (NCT04442607)
- Testing
- artificial intelligence image processing
- Where
- Belgium
- Volunteers
- 856 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Colorectal Polyp
Comparative Study of Anchoring-tip vs. Conventional EMR of Colorectal Polyps
Endoscopic mucosal resection (EMR) is an effective and has been widely used technique for the treatment of superficial colorectal neoplasms.
- Trial name
- NCT04825457
- Testing
- Anchoring-tip vs. Conventional
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Chilgok Hospital
Surveillance Endoscopy for Colorectal Cancer, Artificial Intelligence
Surveillance Modified by Artificial Intelligence in Endoscopy (SMARTIE)
Evaluation of an artificial intelligence system for polyp detection (CADe)
- Conditions
- Surveillance Endoscopy for Colorectal Cancer, Artificial Intelligence, Polyps of Colon, CADe
- Trial name
- SMARTIE (NCT05006092)
- Testing
- ENDOMIND
- Where
- Germany
- Volunteers
- 1,149 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Colorectal Adenoma, Colorectal Cancer Control and Prevention
6-year Follow-up Data After the Berberine Intervention Trial
Colorectal cancer (CRC) is a common malignancy of the digestive tract, which constitutes a major public health burden. Almost 90% of CRC cases progress from precursor adenomatous polyps through adenoma-carcinoma sequence.
- Conditions
- Colorectal Adenoma, Colorectal Cancer Control and Prevention, Colorectal Polyps
- Trial name
- NCT06629051
- Testing
- Berberine Hydrochloride
- Where
- China
- Volunteers
- 891 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Colorectal Neoplasms
European Polyp Surveillance Trial
This protocol describes the epos (ancient greek (Επος) for "story") of a group of related clinical trials aiming at addressing one of the most important unsolved challenges in the prevention of colorectal cancer (one of our major…
- Trial name
- EPoS (NCT02319928)
- Testing
- Colonoscopy
- Where
- Spain
- Volunteers
- 20,000 people
- Sponsor
- Asociación Española de Gastroenterología
Adenomatous Polyp of Colon
Registry Evaluation of a Double Balloon Accessory Device
This study is collecting standard of care information pertaining to the use of the accessory device and patient outcomes when this double balloon accessory device is used during endoscopic procedures in the colon.
- Trial name
- NCT03942965
- Testing
- Double balloon accessory device
- Where
- 3 sites in United States
- Volunteers
- 165 people
- Sponsor
- Lumendi, LLC
Colon Polyp, Adenoma
Six Versus Twelve Month Index Follow-up After Large Colon Polyp Resection
The study will compare the use of a 6-month follow-up vs a 12-month follow-up after the removal of a large non-pedunculated polyp 20-50mm in size and without high grade dysplasia.
- Conditions
- Colon Polyp, Adenoma, Serrated Polyp, Recurrence, Local Neoplasm
- Trial name
- STARLING (NCT07198945)
- Testing
- 6-month follow-up, 12-month follow-up
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 546 people
- Sponsor
- Indiana University
Polyp Colorectal, Rectal Adenoma
GelPOINT® Path-Assisted Endoscopic Removal of Colon and Rectal Polyps: A Feasibility and Safety Study
This prospective, single-center, observational feasibility and safety study will evaluate the use of the GelPOINT® Path transanal access platform during endoscopic submucosal dissection (ESD) for the removal of colorectal polyps.
- Conditions
- Polyp Colorectal, Rectal Adenoma, Adenoma Colon Polyp
- Trial name
- NCT07723937
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Baylor College of Medicine
Colorectal Cancer, Polyp of Colon
Hybrid-sensor Breath Analysis for Colorectal Cancer Screening
The aim of this project is to promote the breath volatile marker concept for colorectal cancer (CRC) screening by advancing developing the application of a novel hybrid analyzer for the purpose.
- Trial name
- HYCOR (NCT05173077)
- Testing
- Identification of specific VOCs in CRC tissue surgery material, Secondary validation study in general CRC screening settings, Breath sampling for VOC detection
- Where
- Latvia
- Volunteers
- 3,000 people
- Sponsor
- University of Latvia