Clinical trials: Pneumoperitoneum
Surgery, Pneumoperitoneum
Intra-Abdominal Pressure Effect on Intra-Abdominal Volume and Airway Pressures During Laparoscopy
During pneumoperitoneum insufflation the insufflated gas increase intra-abdominal pressure. The generated pressure can lead to a different increase in volume depending on the abdominal cavity and patients' characteristics.
- Conditions
- Surgery, Pneumoperitoneum, Intra Abdominal Pressure
- Trial name
- NCT04468698
- Testing
- Peritoneum insufflation
- Where
- Spain
- Volunteers
- 204 people
- Sponsor
- Hospital Universitario La Fe
Benign Neoplasm of Cervix Uteri, Gynecological Laparoscopy
The Effects of CO2 Pneumoperitoneum at Different Temperature in Laparoscopic Surgery
Objective: It is recommended to heat and humidify CO2 in laparoscopic surgery to prevent postoperative pain and hypothermia but information about its effects on hemodynamic and respiratory parameters is limited.
- Trial name
- NCT04508387
- Testing
- Group HH (heated-humidified)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ege University
Pain, Pneumoperitoneum
Comparison of Pneumoinsufflation Modes and Pressure Settings in Gynecology
This study seeks to evaluate post-operative patient pain and quality of life, and intra-operative hemodynamic status and changes in inflammatory markers, with use of a pressure-barrier insufflator and conventional insufflator at…
- Conditions
- Pain, Pneumoperitoneum, Inflammation, Quality of Life
- Trial name
- NCT02853591
- Testing
- Pneumoinsufflator mode and setting
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Pneumoperitoneum, Heart Output Disorder
Arterial and Plethysmographic Waveforms Variables as Predictors of Hemodynamic Response to Pneumoperitoneum
Laparoscopic surgery is frequently associated with hemodynamic changes due to pneumoperitoneum (PnP). Those complex hemodynamic changes are difficult to predict and occasionally they require active therapeutic interventions or…
- Trial name
- SPV-PnP (NCT01867814)
- Testing
- Pneumoperitoneum
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Carmel Medical Center
Laparoscopy, Pneumoperitoneum
The Turbine-based Insufflator Safety and Feasibility Study
The turbine-based insufflator for minimal access surgery provides a new technological basis for minimal invasive surgery insufflation.
- Trial name
- TBI (NCT06319053)
- Testing
- Turbine-based insufflator
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Erasmus Medical Center
Pneumoperitoneum
Influence of Posture and Gas Insufflation on Perioperative Lung Function
Perioperative airway resistance and lung function are evaluated perioperatively in patients, who undergo surgical procedures in different postures and with or without gas insufflation into the peritoneal cavity.
- Trial name
- NCT00948571
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Kliniken Essen-Mitte
Prostate Cancer
The Impact of Low Pressure Pneumo in RARP
The purpose of this study is to evaluate clinical significance of low pressure pneumoperitoneum during robotically assisted radical prostatectomy (RARP).
- Trial name
- NCT03370016
- Testing
- Amount of Pneumoperitoneum Pressure applied during RARP
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- Metro Health, Michigan
Gynecologic Surgery
Low Versus Standard Pressure Pneumoperitoneum
The role of laparoscopy in gynecological and gyne-oncological surgery has dramatically increased over the past decades. Although laparoscopic procedure has several advantages over open surgery such as reduced blood loss, faster…
- Trial name
- NCT04947982
- Testing
- carbon dioxide
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Gynecologic Diseases
AirSeal®Insufflation Trocar/CO2 Absorption Study
The purpose of this study is to compare carbon dioxide (CO2) absorption during gynecologic laparoscopy using the AirSeal® valveless trocar system versus standard insufflation trocars at intra-abdominal pressures of 10 and 15…
- Trial name
- NCT02654808
- Testing
- AirSeal trocar, Standard trocar
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Columbia University
Optic Nerve Sheath Diameter, Pneumoperitoneum
Comparison of Changes of ONSD Between Groups of Laparoscopic Surgery With and Without Epidural Saline Injection
This study targets patients undergoing laparoscopic gastric cancer surgery. The investigators would like to compare two factors that influence intracranial pressure through optic nerve sheath diameter measurement.
- Conditions
- Optic Nerve Sheath Diameter, Pneumoperitoneum, Epidural
- Trial name
- NCT04758013
- Testing
- Epidural injection through thoracic epidural catheter, Without epidural injection
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Keimyung University Dongsan Medical Center
Atelectasis
Effects of Pneumoperitoneum on Dynamic Alveolar Stress-strain in Anesthetized Pediatric Patients
General anesthesia is associated with loss of pulmonary functional residual capacity and consequent developement of atelectasis and closure of the small airway.
- Trial name
- NCT04183309
- Testing
- Measure the transpulmonary pressure in pediatric patients
- Where
- Argentina
- Volunteers
- 20 people
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Obesity, Morbid, Bariatric Surgery Candidate
Optical Trocar to Create the Pneumoperitoneum in Bariatric Patients
Laparoscopic bariatric surgery are becoming the most used procedure to treat the obesity. To facilitate safe initial access to the abdominal cavity, we insert an optical viewing trocar at the left hypocondrium.
- Conditions
- Obesity, Morbid, Bariatric Surgery Candidate, Surgery-Complications
- Trial name
- NCT06207357
- Testing
- optical trocar to create the pneumoperitoneum for bariatric surgery
- Where
- Italy
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Laparoscopic Gynecological Surgery
Effects of Standard and Modified Z-Trendelenburg Positions on Cerebral Oxygenation and Optic Nerve Sheath Diameter
The purpose of this study is to compare the effects of the standard Trendelenburg position and the modified Z-Trendelenburg position on cerebral oxygenation and optic nerve sheath diameter (ONSD) in patients undergoing…
- Trial name
- MOD-TREND (NCT07632287)
- Testing
- Standard Trendelenburg Position, Modified Z-Trendelenburg Position
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Gastroesophageal Reflux in Laparoscopy
Risks of Gastroesophageal Reflux in the Endotracheal Intubation or the I-gel
In the use of the second supraglottic airway device- i-gel in the laparoscopic pneumoperitoneum and Trendelenburg (LPT) surgical positioning, our data reported that the leak fraction in the i-gel group was higher than in the…
- Trial name
- NCT03634449
- Testing
- i-gel, endotracheal tube
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Esophageal Achalasia, Gastroparesis
Respiratory and Hemodynamic Implications of Endoscopic Myotomy of the Esophagus and Stomach
The goal of this observational study is to learn about hemodynamic and respiratory repercussions during general anesthesia in patients with achalasia or gastroparesis who underwent an endoscopic treatment such as a peroral…
- Trial name
- NCT05602272
- Testing
- General anesthesia for per-oral endoscopic myotomy
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Laparoscopic Carbon Dioxide Measurement
Intraperitoneal Carbon Dioxide Concentration Measurement During Standard Laparoscopy With a New Airseal Access Port
The new AirSeal access port for laparoscopic surgery does not use a mechanical valve on the port to maintain gas in the peritoneal cavity. It uses an invisible barrier created by high flow gas jets within the port.
- Trial name
- NCT01017887
- Testing
- Airseal access port for laparoscopic surgery, Standard Laparoscopy ports
- Sponsor
- Baystate Medical Center
Pneumoperitoneum, Trendelenburg Position
End-expiratory Pressure During Laparoscopic Surgery in the Trendelenburg Position by Electrical Impedance Tomography
Pneumoperitoneum (PNP) and the position of the patient required for laparoscopic surgery lead to pathophysiological changes that complicate anesthesia.
- Conditions
- Pneumoperitoneum, Trendelenburg Position, Laparoscopic Surgery
- Trial name
- CP-EIT (NCT06481124)
- Testing
- electrical impedance tomography
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Pain, Postoperative, Postoperative Pain
Intraperitoneal Aerosolized Delivery of a Local Anesthetic for Post Operative Pain Management. A Double Blind, Randomised Controlled Clinical Trial.
The purpose of this study is to determine the effectiveness of aerosolized pain medication (.5% bupivicaine) delivered into the peritoneal cavity after laparoscopic gastric bypass surgery.
- Conditions
- Pain, Postoperative, Postoperative Pain, Abdominal Pain, Obesity
- Trial name
- NCT00286286
- Testing
- Intraperitoneal Aerosolization System, IntraMyst
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Northgate Technologies
Oophorectomy, Oxidative Stress
Role of Oxidative Stress in Ovarian Tissue After CO2-pneumoperitoneum Application-induced I/R
Because of cellular changes in response to ischemia and a following period of reperfusion, damages to organs and different tissues occur.
- Conditions
- Oophorectomy, Oxidative Stress, Ischemia Reperfusion Injury
- Trial name
- NCT04493983
- Testing
- laparoscopic salpingo-oophorectomy, Laparoscopic bilateral salpingo-oophorectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ismet Hortu
Laparoscopic Nephrectomy, Cerebral Oxygen Saturation
Pneumoperitoneum and Cerebral Oxygenation
In this study, the changes in cerebral oxygen saturation due to low and high pressure pneumoperitoneum implementation were measured in patients who underwent laparoscopic nephrectomy.
- Trial name
- NCT04671121
- Testing
- Standart pressure pneumoperitoneum, Low pressure pneumoperitoneum
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Ondokuz Mayıs University