Clinical trials: Pneumonia, Interstitial
Lip, Lip Cancer
T1 Squamous Cell Carcinomas of the Lip
The purpose of this study is to investigate the risk of recurrence and metastasis in patients treated with different surgical margins (5mm vs 10mm) for a T1 squamous cell carcinoma of the lip.
- Conditions
- Lip, Lip Cancer, Lip SCC, Squamous Cell Carcinoma
- Trial name
- NCT05610293
- Where
- 3 sites in Netherlands
- Volunteers
- 300 people
- Sponsor
- Maastricht University Medical Center
Idiopathic Pulmonary Fibrosis
A 2-Part, Phase 2 Open-label and Crossover Study of Belumosudil for Treatment of Idiopathic Pulmonary Fibrosis
This Phase 2 study is to be conducted to evaluate the safety, tolerability, and activity of 400 mg of belumosudil orally (PO) once-daily (QD) compared to Best Supportive Care (BSC) in male and postmenopausal/surgically sterilized…
- Trial name
- NCT02688647
- Testing
- Belumosudil, BSC
- Where
- 10 sites in United States
- Volunteers
- 76 people
- Sponsor
- Kadmon Corporation, LLC
Interstitial Lung Disease, Interstitial Pneumonia
Clinical Characteristics of Interstitial Pneumonia With Autoimmune Features (IPAF) - a Multicenter Prospective Study
Interstitial pneumonia with autoimmune features (IPAF) was defined in 2015 by the Working Group of the European Respiratory Society (ERS) and the American Thoracic Society (ATS) as interstitial pneumonia with some clinical and/or…
- Conditions
- Interstitial Lung Disease, Interstitial Pneumonia, Interstitial Fibrosis, Autoimmune Diseases
- Trial name
- NCT03870828
- Testing
- Bronchoalveolar lavage and taking bronchial mucosa samples, 6minute walk test, Arterial blood gas
- Where
- 7 sites in Italy, Poland
- Volunteers
- 210 people
- Sponsor
- Medical University of Silesia
Non-Small Cell Lung Cancer (NSCLC)
Interstitial Pneumonitis Associated With EGFR-TKI and Combined With PD-1/PD-L1
Importance: EGFR tyrosine kinase inhibitors (EGFR-TKIs) and PD-1/PD-L1 immune checkpoint inhibitors are widely used in the treatment of non-small cell lung cancer (NSCLC).
- Trial name
- NCT07036016
- Testing
- EGFR-TKI, PD-1/PD-L1 inhibitor, EGFR-TKI combined with PD-1/PD-L1
- Volunteers
- 67,818 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Interstitial Lung Disease, Connective Tissue Diseases
Impact of Capillaroscopy in the Investigation of Diffuse Interstitial Pneumonias
The investigators hypothesize that in patients with a new diagnosis of Pulmonary Interstitial Disease (PID), adding capillaroscopy to standard care increases the proportion of patients receiving a diagnosis of PID-Connective…
- Trial name
- CAPID (NCT07283081)
- Testing
- capillaroscopy
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Bordeaux
Locally Advanced Non Small Cell Lung Cancer
Prevention of Locally Advanced NSCLC Radiotherapy Pneumonia by Inhaling Beclomethasone Propionate
Radical radiotherapy is the main treatment of locally advanced lung cancer, and radiation pneumonia is the main toxic effects of radiotherapy.
- Trial name
- NCT03886441
- Testing
- Beclomethasone propionate
- Where
- China
- Volunteers
- 194 people
- Sponsor
- Tongji University
Sjogren's Syndrome
Cyclosporine A in the TReatment of Interstitial Pneumonitis Associated With Sjogren's Syndrome
The purpose of this large multicenter, randomized, double-blinded, controlled clinical study is to investigate the efficacy and safety of Cyclosporin A for primary Sjogren's syndrome associated pneumonitis(pSS-IP), which has…
- Trial name
- CTRIPS (NCT02370550)
- Testing
- Cyclosporin A, Prednisone, Calcium carbonate D
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Peking University People's Hospital
Covid19
Micronized and Ultramicronized Palmitoylethanolamide in COVID-19 Patients
SARS-CoV-2 infection is a condition characterized by excessive leukocyte infiltration, massive release of chemokines, proteases and cytokines, the so-called "cytokine storm", which promote the inflammatory process and contribute…
- Trial name
- NCT04568876
- Testing
- Micronized and ultra-micronized Palmitoylethanolamide (mPEA and umPEA, 300mg + 600mg) oral suspension, Standard Therapy
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Epitech Group SpA
COPD, Interstitial Pneumonia
Perioperative Risk Factors Related to the Prognosis of Lung Transplantation: A Retrospective Study
This study analyzes patients who underwent lung transplantation at the First Affiliated Hospital of Zhejiang University from 2017 to 2024, focusing on anesthesia's impact on post-op results.
- Conditions
- COPD, Interstitial Pneumonia, Bronchiectasis, Respiratory Failure
- Trial name
- NCT06922916
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Zhejiang University
Nose; Anomaly
Objective Assessment for Cleft Lip Nasal Deformity Correction
Rhinoplasty remains one of the most challenging procedures in plastic surgery, and patients with cleft lip nasal deformity pose an even greater challenge, in which biggest issue is to achieve caudal nose harmony and creation of…
- Trial name
- NCT03683199
- Testing
- Rhinoplasty
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Assiut University
COVID, Covid-19
Treatment of Covid-19 Associated Pneumonia With Allogenic Pooled Olfactory Mucosa-derived Mesenchymal Stem Cells
Treatment of patients with Covid-19 associated pneumonia using intravenous injection of allogenic pooled olfactory mucosa-derived mesenchymal stem cells
- Conditions
- COVID, Covid-19, Coronavirus, Pneumonia
- Trial name
- NCT04382547
- Testing
- Allogenic pooled olfactory mucosa-derived mesenchymal stem cells, Standard treatment according to the Clinical protocols
- Where
- Belarus
- Volunteers
- 32 people
- Sponsor
- Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Covid-19, Pulmonary Fibrosis
Development of Interstitial Lung Disease (ILD) in Patients With Severe SARS-CoV-2 Infection (COVID-19)
COVID-19, the infectious disease caused by the novel coronavirus SARS-CoV-2, currently poses a global economic, social, political and medical challenge.
- Trial name
- CovILD (NCT04416100)
- Testing
- Pulmonary function tests, Imaging, Blood sampling
- Where
- Austria
- Volunteers
- 130 people
- Sponsor
- Medical University Innsbruck
Breast Cancer, Colorectal Cancer
Validation of a Screening Tool in Geriatric Oncology
RATIONALE: A screening questionnaire may help doctors plan better treatment for older patients with cancer. PURPOSE: This clinical trial is studying a questionnaire in screening older patients with cancer.
- Conditions
- Breast Cancer, Colorectal Cancer, Head and Neck Cancer, Lung Cancer
- Trial name
- ONCODAGE (NCT00963911)
- Testing
- Geriatric screening tests, Multidimensional geriatric assessment
- Where
- France
- Volunteers
- 1,674 people
- Sponsor
- Institut Bergonié
Idiopathic Pulmonary Fibrosis, Interstitial Pneumonia
Case-Control Study of Fibrotic Interstitial Lung Disease (ILD) and Cardiac Disease / Interventions.
There is a rare condition causing scarring of the lungs termed interstitial lung disease. This comprises a group of conditions which can be divided into separate diseases.
- Trial name
- NCT01154998
- Where
- United Kingdom
- Volunteers
- 360 people
- Sponsor
- St George's Healthcare NHS Trust
Lip, Prosthesis User
Facial Scanning for Lip Support Assessment in Full Arch Implant Rehabilitations
Lip support plays an important role in facial esthetics, being a relevant factor when realizing full arch implant supported rehabilitations.
- Conditions
- Lip, Prosthesis User, Soft Tissue
- Trial name
- NCT04753866
- Testing
- Facial scanner
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Ozone Therapy for Covid 19 Pneumonia Patients
Evaluation of Post-covid 19 Patients Who Receive Ozonetheraphy With Thorax CT
It is known that enhances wound healing by oxidative stress and supports immune system besides it is cheap and has not any side effects.
- Trial name
- NCT04789395
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Radiation Pneumonitis
The Efficacy of Babaodan Capsules in Preventing Radiation Pneumonia
Radiation pneumonitis (RP) is a common complication of radiotherapy for thoracic tumors, and the incidence rate of grade 2 or above RP is 20% -40%; The use of antibiotics after secondary bacterial infection due to radiation…
- Trial name
- NCT06079931
- Testing
- Babaodan Capsule
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
COVID, Pneumonia, Viral
Lung Damage Caused by SARS-CoV-2 Pneumonia (COVID-19)
Pneumonia is a recurrent element of COVID-19 infection, it is often associated with development of respiratory failure and patients frequently need various degrees of oxygen therapy up to non invasive ventilation (NIV-CPAP) and…
- Conditions
- COVID, Pneumonia, Viral, Barotrauma, Interstitial Lung Disease
- Trial name
- SequelaeCov (NCT04435327)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Milano Bicocca
Interstitial Pneumonitis, Polymyositis
Investigation in Myositis-associated Pneumonitis of Prednisolone And Concomitant Tacrolimus
The purpose of the study is to evaluate the efficacy and safety of the combination treatment of tacrolimus and corticosteroid in polymyositis/dermatomyositis patients with interstitial pneumonitis with comparison against…
- Conditions
- Interstitial Pneumonitis, Polymyositis, Dermatomyositis
- Trial name
- IMPPACT (NCT00504348)
- Testing
- Tacrolimus
- Where
- 11 sites in Japan
- Volunteers
- 25 people
- Sponsor
- Tokyo Medical and Dental University
Recurrent Hypopharyngeal Squamous Cell Carcinoma, Recurrent Laryngeal Squamous Cell Carcinoma
Cediranib Maleate in Treating Patients With Recurrent or Newly Diagnosed Metastatic Head and Neck Cancer
This phase II trial is studying how well cediranib maleate works in treating patients with recurrent or newly diagnosed metastatic head and neck cancer.
- Conditions
- Recurrent Hypopharyngeal Squamous Cell Carcinoma, Recurrent Laryngeal Squamous Cell Carcinoma, Recurrent Laryngeal Verrucous Carcinoma, Recurrent Lip and Oral Cavity Squamous Cell Carcinoma
- Trial name
- NCT00458978
- Testing
- Cediranib Maleate, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- National Cancer Institute (NCI)