Clinical trials: Plasma Lipids
Dyslipidemias
Effect of Calisthenic Exercise Training Combined With Aerobic Exercise in Patients With Dyslipidemia
Dyslipidemia is expressed as the serum concentration of lipid molecules with different structures outside the normal level. Deviation of serum lipid level from normal is accepted as the primary or most important factor in various…
- Trial name
- NCT06008912
- Testing
- Calisthenic Exercises, Aerobic Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Çankırı Karatekin University
Cardiovascular Diseases, Lipid Disorder
SRMA of the Effect of Soy Milk vs Cow's Milk on Cardiometabolic Outcomes
Dairy consumption has shown associations with decreased incidence of cardiometabolic diseases. With the growing interest in plant-based eating, and the mounting evidence for the cardiovascular benefits of plant forward diets…
- Conditions
- Cardiovascular Diseases, Lipid Disorder, Metabolic Disease, Non-Alcoholic Fatty Liver Disease
- Trial name
- NCT05637866
- Testing
- Soy milk
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Rheumatoid Arthritis
n-3 and n-6 Fatty Acids in Rheumatoid Arthritis
Purpose: To investigate into the differential effects of polyunsaturated fatty acids as compared to standard control therapy (olive oil) on disease activity and biochemical parameters in patients with rheumatoid arthritis (RA)…
- Trial name
- NCT01179971
- Testing
- Fish oil, gamma-linolenic acid
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Hypercholesterolemia
Effects of Lactobacillus Delbruckii Lactis DN111244 Fermented Milk Consumption on Plasma Lipids Levels in Hypercholesterolaemic Adults
The objective of this study is to investigate the effect of Lactobacillus Delbruckii lactis (DN111244) fermented milk consumption on relative change of plasma LDL-cholesterol concentration in hypercholesterolaemic adults after 8…
- Trial name
- NCT01353820
- Testing
- 1- Low fat drinkable fermented by Lactobacillus Delbruckii lactis (DN111244) - >10E8 <5.10E9 cfu/mL, 2- Low fat drinkable fermented by S. thermophilus and L. bulgaricus
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Hypertriglyceridemia
Interest of High-speed Centrifugation for Measuring Anti-Xa Activity on Lipemic Plasma
Some hemostasis techniques require spectrophotometric measurements. These are then subject to interference from the sample's lipemia (postprandial, hypertriglyceridemia, etc.), which risks distorting the results; this is…
- Trial name
- LCGV (NCT07200674)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Strasbourg, France
HIV Infections, Metabolism, Lipids
An Open-label, Non-randomized, Single-arm Study to Investigate the Mechanism(s) by Which Nevirapine Increases Plasma HDL in HIV+ Subjects
1. In order to obtain further insight as to how NVP affects HDL metabolism, the in vivo kinetics of the HDL apolipoprotein, Apo A-1, before and 6 weeks after initiation of NVP containing treatment were evaluated.
- Trial name
- NCT00144261
- Testing
- nevirapine
- Where
- 3 sites in Netherlands, United Kingdom
- Volunteers
- 15 people
- Sponsor
- Boehringer Ingelheim
Prediabetes, Type 2 Diabetes
Effects of Dried Whole Fruits on Metabolism in Diabetes
Diabetes becomes epidemic in worldwide countries. Diabetes Canada indicated that 30% of adults in Manitoba are diabetes or prediabetes. Nine out of ten diabetic patients are type 2 diabetes (T2D).
- Trial name
- NCT07354386
- Testing
- Freeze dried whole Saskatoon berry, Freeze dried apple slice bulk
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- University of Manitoba
Cardiovascular Disease, Dyslipidemia
Effects of High Fruit, Vegetable, and Dairy Intake on Plasma Lipids and Blood Pressure in Healthy Individuals
The Dietary Approaches to Stop Hypertension (DASH) trial has been shown to reduce blood pressure and plasma total and LDL-cholesterol (C) compared to a Western diet, but shows no benefit on other blood lipid variables associated…
- Conditions
- Cardiovascular Disease, Dyslipidemia, Blood Pressure
- Trial name
- NCT01404897
- Testing
- Dietary Intervention
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Cardiovascular Diseases, Oxidative Stress
Effects of Prolonged Delivery of Nitric Oxide Gas on Plasma Reduction-Oxidation Reactions in Cardiac Surgical Patients
This study is an ancillary (add-on) study to the clinical trial entitled "Effect of Nitric Oxide in Cardiac Surgery Patients With Endothelial Dysfunction", which has Clinical Trials.gov identifier NCT02836899.
- Conditions
- Cardiovascular Diseases, Oxidative Stress, Endothelial Dysfunction
- Trial name
- NCT04022161
- Testing
- Nitrogen Gas for Inhalation, Blood withdrawal, Nitric Oxide
- Where
- 2 sites in United States, United Kingdom
- Sponsor
- Massachusetts General Hospital
Cardiovascular Disease
Impact of Meal Fatty Acids on Postprandial Vascular Reactivity
Cardiovascular disease (CVD) is the leading cause of death in women. Premenopausal women have a lower risk of CVD compared with men of a similar age. However, the incidence of CVD increases greatly after the menopause.
- Trial name
- DIVAS-2 (NCT02144454)
- Testing
- Saturated fat, Monounsaturated fat, n-6 polyunsaturated fat
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Reading
Healthy Donor
Lipid Characterisation of Plasma Microparticles in a Large Population of Healthy Donors
Extracellular vesicles (EVs) are membrane structures containing numerous mediators categorised according to their size and mode of production.
- Trial name
- MicroLipids (NCT06183632)
- Testing
- blood sampling
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Myocardial Infarction
Effects of Bilberry and Oat Intake After Type 2 Diabetes and/or MI
Background: Bilberries from Sweden, rich in polyphenols, have shown cholesterol-lowering effects in small studies, and the cholesterol-lowering properties of oats, with abundant beta-glucans and potentially bioactive…
- Trial name
- BioDiaMI (NCT03620266)
- Testing
- Bilberry, Bioprocessed oat bran, Combination bilberry/oats
- Where
- 8 sites in Denmark, Sweden
- Volunteers
- 900 people
- Sponsor
- Ole Frobert, MD, PhD
Hyperlipidemias
Plasma Lipoprotein Response to Glucagon-like Peptide-2
Some of the fat (triglyceride) from the food humans eat gets stored in the bowel. This triglyceride can then be released into the blood when another meal is consumed or in response to hormones.
- Trial name
- GLP-2 Plasma (NCT03422666)
- Testing
- Teduglutide
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Primary Hypercholesterolaemia
ORBITAL: Open-Label Primary Care Study: Rosuvastatin Based Compliance Initiatives Linked To Achievement Of LDL Goals
24 week open label study to compare the treatment either with rosuvastatin or rosuvastatin plus initiatives to improve compliance.
- Trial name
- NCT00396240
- Testing
- Rosuvastatin, Initiatives to improve compliance
- Volunteers
- 1,294 people
- Sponsor
- AstraZeneca
Ketone Body, Lipid Metabolism
Acute Effects of MCT Formulations on Beta-Hydroxybutyrate Response, Lipid Profile, and Glucose Levels in Healthy Adults
The goal of this clinical trial is to evaluate the effects of medium-chain triglycerides (MCTs), delivered in different formulations, on beta-hydroxybutyrate response (as a marker of ketone body production), lipid metabolism, and…
- Conditions
- Ketone Body, Lipid Metabolism, Glucose Response
- Trial name
- NCT07718048
- Testing
- MCT Beverage, LCT Beverage, Synthetic MCT Powder
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Milan
Endothelial Dysfunction
Evaluation of Lipid Emulsion on GCX in Critically Ill Patients
Characterisation of the lipidome and parenteral nutrition modulate the endothelial glycocalyx. The aim of the study A is to detect any influence of the lipid emulsion on the endothelial glycocalyx in patients in critical care.
- Trial name
- NCT03216850
- Testing
- Sublingual microcirculation assessment
- Where
- Czechia
- Volunteers
- 15 people
- Sponsor
- University Hospital Hradec Kralove
Healthy
Krill Oil as Supplementation to Healthy Young Adults.
The purpose of this study is to examine whether 4 weeks daily intake of krill oil can change the omega-3 index (content of the long chained fatty acids EPA and DHA in relation to the total fatty acids) in the membrane in red…
- Trial name
- NCT02053415
- Testing
- Krill oil low dose, Krill oil high dose
- Where
- Norway
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Dyslipidemia
A Study of the Kinetics of a 13C-Cholesterol Infusate in Healthy Male Subjects (0000-108)(COMPLETED)
This is a 2-part pilot study in healthy male subjects to evaluate plasma enrichment kinetics of [13C3,4]-cholesterol (Part I) and to assess the test-retest reproducibility (Part II) of Reverse Cholesterol Transport (RCT)…
- Trial name
- NCT01101763
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Early-Stage Lung Cancer
Detection of Lung Cancer by Plasma Lipids
There are no reliable blood-based tests currently available for early-stage lung cancer diagnosis. We try to establish a highly accurate method for detecting early-stage lung cancer by combining machine learning with untargeted…
- Trial name
- ELAID (NCT04287712)
- Testing
- Plasma lipids
- Where
- China
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Healthy
Bioavailability of Fatty Acids From Krill Oil and Krill Meal and Fatty Acids From Fish Oil in Healthy Subjects.
The purpose of the study is to compare the acute bioavailability of two different krill oil products called krill oil and krill meal in comparison to fish oil product.
- Trial name
- RISU (NCT02089165)
- Testing
- Krill oil, Krill meal, Fish oil
- Where
- Finland
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Olympic Seafood AS