Clinical trials: Pigmentation
Neonatal Jaundice
The Effect of Skin Color Scale Material Used by Families at Home in the Postnatal Period on the Process of Hospital Admission Due to Jaundice and Breastfeeding Parameters
The aim of this research is to evaluate the effect of the Skin Color Scale Material used by families in the postnatal period on the hospital admission process due to jaundice and breastfeeding parameters.
- Trial name
- NCT07386093
- Testing
- Experiment Group, control group
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Gingival Pigmentation
Effect of Oxidant Gel and Anti-oxidant Gel on Wound Healing After Gingival Depigmentation
To evaluate effect of Oxidant (Oxygen Releasing Oral Gel) with Coe-Pak versus Anti-oxidant (Nano-emulsion complex propolis and vitamin C gel) with Coe-Pak on wound healing, pain, patient satisfaction after gingival depigmentation
- Trial name
- NCT05837416
- Testing
- blue®m Gel, NBF GINGIVAL GEL®, COE-PAK™
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Skin Pigmentation
Process Validation in Dermatology: Assessing Methods for UV Exposure (Artificial Source vs. Sunlight) and Efficacy Evaluation of Anti-Tanning Agents
The rationale of this study is to establish a robust method for assessing sun protection product efficacy in preventing erythema and tanning.
- Trial name
- NCT06384092
- Testing
- Test Sun Protection Cream, Benchmark Sun Protection Cream
- Where
- India
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Sun Damaged Skin
Photoprotective Effects of a SPF50+ Sunscreen on Skin Genotoxicity Induced by Repeated Chronic Outdoor Sun Exposure
Between 2 and 3 million non-melanoma skin cancers and 132,000 melanoma skin cancers occur globally each year. Sun protection continues to be a major public health issue and has always been a priority research area for Pierre…
- Trial name
- NCT05926791
- Testing
- Cosmetic product
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Skin Ageing, Skin
Skin Type Determination Using Image Artificial Intelligence
Skin color, how easily a person burns or tans in the sun (skin phototype), and the amount of chronic sun damage in the skin are important factors in skin health.
- Trial name
- SPAI (NCT07765303)
- Testing
- Skin imaging and skin characteristic assessment
- Where
- 13 sites in Australia, Brazil and 9 more
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Region Skane
Vitiligo
Building an Assessment Model for Vitiligo Activity and Prognosis Using Peripheral Blood Cytokine Profiles
Vitiligo is a chronic autoimmune disorder characterized by depigmented patches on the skin, which can pose significant psychosocial challenges, particularly for individuals with darker skin tones.
- Trial name
- NCT07298551
- Testing
- Serum Cytokine Assay
- Where
- China
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Vitiligo
T Central Memory Cells in Early Localized Non-Segmental Vitiligo
Assessing the level of circulating TCMs (cluster of differentiation (CD) 8+, CD3+,C- chemokine receptor (CCR)7, cluster of differentiation 45 receptor (CD45R) cells) in early localized vitiligo cases prior to treatment and after…
- Trial name
- NCT05706636
- Testing
- oral mini pulse, Topical cream, targeted phototherapy
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Melasma
Curcuma Xanthorriza Roxb. 10% Cream for Melasma
Melasma is an acquired hyperpigmentation disorder with a multifactorial etiology and complex pathogenesis that can significantly diminish the quality of life for affected patients.
- Trial name
- NCT06153134
- Testing
- 10% Curcuma xanthorriza Roxb., 2% Kojic Acid
- Where
- Indonesia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Healthy
Plant Pigments for Human Health: Impact of Lycopene and Anthocyanins on Bioefficacy of Provitamin A Carotenoids From Carrots
The proposed research will help characterize the impact that simultaneous consumption of anthocyanins and carotenoids has on the bioavailability of the provitamin A carotenoids a-carotene and b-carotene and the non-provitamin A…
- Trial name
- NCT05319548
- Testing
- Purple-Red Carrot Juice, Red Carrot Juice, Purple Carrot Juice
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Melasma
Evaluation of Laser and Tranexamic Acid in Treatment of Melasma
Melasma Is an acquired, chronic, recurrent, symmetrical hypermelanosis, which is characterized by brown patches of variable darkness on sun exposed areas of the body. It is more common in women.
- Trial name
- NCT04599205
- Testing
- Tranexamic acid
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Sunscreening Agent
18790 - Sun Protection Factor Assay
To evaluate the Sun Protection Factor (SPF) efficacy on human skin.
- Trial name
- SPF (NCT02695303)
- Testing
- Coppertone (BAY 987516)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bayer
Melasma
Sylfirm X Radiofrequency Microneedling for the Treatment of Melasma
Microneedling radiofrequency technology has been shown in clinical studies to improve skin quality, tone, pigment, and to treat various skin conditions related to aging.
- Trial name
- NCT06415435
- Testing
- Radiofrequency Microneedling
- Where
- 3 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Benev Company, Inc.
Pigmentation
The Effect of Topical Sunscreen Plus Antioxidant Against the Visible Light Biological Effects
Visible light is known to induce pigmentation in darker skin types. The investigators aim to study the effects of visible light on the skin after topical application of sunscreen plus antioxidant.
- Trial name
- NCT03065582
- Testing
- Topical Product A, Topical Product B, Topical Product C
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Collagen Degeneration, Wrinkle
The Effects of Almond on Facial Skin Collagen and Wrinkles
Investigate the effects of almond consumption on collagen production, elastin levels, wrinkles, and pigmentation among premenopausal women and postmenopausal women belonging to all Fitzpatrick skin types.
- Conditions
- Collagen Degeneration, Wrinkle, Pigmentation, Elastic Skin
- Trial name
- NCT06074276
- Testing
- Food: whole almonds, Food: non-nut snack
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Sunscreening Agent
Sun Protection Factor Assay (SPF Assay 18677)
To evaluate the Sun Protection Factor efficacy on human skin.
- Trial name
- SPF Assay (NCT02825017)
- Testing
- Coppertone (BAY 987517)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bayer
Solar Lentigines
A Fixed Triple Combination Cream for Solar Lentigines Associated to Cryotherapy
To evaluate safety and efficacy of Tri-Luma® cream as an adjunctive treatment to cryotherapy when used in the pre- and post-procedure phases for the treatment of solar lentigines on the back of the hands and in the prevention of…
- Trial name
- NCT01778179
- Testing
- Tri-luma, Cryotherapy (CRY-AC3® device)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hexsel Dermatology Clinic
Melasma
Inflammation in Melasma: Study of Its Infiltrate and the Expression of Acute and Chronic Mediators
Melasma is an acquired hyperpigmentary disorder that commonly affects women from Asia and Latin-America.There is evidence of subclinical inflammation supported by diffuse spectrometry and by prominent inflammatory cells in…
- Trial name
- NCT01952379
- Where
- Mexico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Raman Spectroscopy
Raman Scattering Spectroscopy to Measure Macular Pigment
This study will evaluate the ease and reliability of Raman scattering spectroscopy, a new technique to measure the amount of the pigment lutein in the retina, the light-sensitive tissue lining the back of the eye.
- Trial name
- NCT00060580
- Testing
- Raman scattering spectroscopy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Vitiligo
Enhanced Transcutaneous Delivery of Betamethasone for the Treatment of Vitiligo
Vitiligo is the commonest acquired depigmenting disorder characterized by loss of melanocytes from the basal layer of skin causing white patches which leads to great psychological distress in many patients.
- Trial name
- NCT05233735
- Testing
- Enhanced Transcutaneous Delivery of Topical Betamethasone after the treatment with Tixel, Topical treatment
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Acanthosis Nigricans, Hyperinsulinemia
Spectroscopic and Colorimetric Analysis of Acanthosis Nigricans in Patients With Hyperinsulinemia
Acanthosis Nigricans is skin disease that associated with hyperinsulinemia. Clinical is velvety hyperpigmented plaques on neck, axilla, groin.
- Conditions
- Acanthosis Nigricans, Hyperinsulinemia, Spectroscopic Analysis
- Trial name
- NCT01125150
- Testing
- Metformin, Dietary Modification
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System