Clinical trials: Physical Therapy Evaluation, open to volunteers
Intrahepatic Cholangiocarcinoma, Perihilar Cholangiocarcinoma
Prognostic Evaluation and Systematic Re-Assessment of Cholangiocarcinoma Therapy
Prospective observational cohort study including patients with a diagnosis of intrahepatic/perihilar cholangiocarcinoma at the central regional multidisciplinary conference, to assess therapy response, patient-reported quality of…
- Trial name
- Re-ACT (NCT07814586)
- Volunteers
- 900 people
- Sponsor
- Karolinska University Hospital
Breast Cancer
Evaluation of the Efficacy of a Physical Therapy-yoga-patient Educational Program for Breast Cancer Patients With Pain Due to Hormonal Therapy Treatment.
As much as 50% of patients treated with hormonotherapy (HT) for breast cancer (BC) suffer from osteoarticular pain during treatment.
- Trial name
- SKYPE2 (NCT04457895)
- Testing
- educational yoga program, no intervention
- Where
- 7 sites in France
- Volunteers
- 108 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Acne Scars, Acne Scars - Atrophic
Safety and Efficacy Evaluation of the Radiofrequency Therapeutic Device for the Treatment of Atrophic Acne Scars
The objective of this clinical trial is to evaluate the safety and effectiveness of a radiofrequency treatment device for the treatment of atrophic acne scars.
- Conditions
- Acne Scars, Acne Scars - Atrophic, Acne Scar, Acne Scarring
- Trial name
- NCT07620769
- Testing
- Investigational Device with the function deactivated, Investigational Device with the function activated, Control Device
- Where
- 4 sites in China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Cerebral Palsy
Changes in Land-Based Motor Function After Routine Hydrotherapy in Children With Cerebral Palsy
This retrospective observational study aims to describe changes in land-based motor function recorded before and after routine hydrotherapy among children with cerebral palsy.
- Trial name
- CP-HYDRO-RETRO (NCT07907445)
- Testing
- Routine Hydrotherapy (Aquatic Rehabilitation)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Karabuk University
Pediatric Cancer Patients
Evaluation of an Exercise Intervention During Intensive Medical Treatment in Pediatric Oncology.
The BEPPO study is a Germany-wide clinical trial investigating whether a structured exercise program can improve physical and mental health in children and adolescents undergoing cancer treatment.
- Trial name
- BEPPO (NCT07647471)
- Testing
- Partially-standardised, supervised, continuity-of-care exercise intervention
- Where
- 13 sites in Germany
- Volunteers
- 346 people
- Sponsor
- Universität Duisburg-Essen
Chronic Venous Disease
Evaluation of Lymphatic Response to Physiotherapy in Patients With Swelling Associated With Superficial Venous Disease
This study seeks to demonstrate the effect of advanced pneumatic compression in treatment naïve patients with CEAP C3 and C4 chronic venous disease.
- Trial name
- NCT07165340
- Testing
- Indocyanine Green near infrared fluorescence imaging, advanced pneumatic compression, Duplex ultrasound
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- The University of Texas Health Science Center, Houston
Bronchiectasis, Quality of Life
Evaluation of the Quality of Life of Patients With DBB With the Installation of OPEP
To carry out an assessment of compliance and quality of life in a population (children and adults) with DDB before and after the use of an oscillating PEP.
- Conditions
- Bronchiectasis, Quality of Life, Physiotherapy
- Trial name
- EQOPEP (NCT06820983)
- Testing
- adult questionnary for parents of children aged 8 to 13, Quality of life questionnaire for children aged 8 to 13, Quality of life questionnaire for adolescents aged 14 to 17
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Low Back Pain
Digital Training Interventions for Low Back Pain
The patients will be clinically examined, as well as evaluated with Patient Reported Outcome Measures (PROMs) and Magnet Resonance Imaging (MRI) at baseline and at follow-ups.
- Trial name
- DigiLum (NCT05679167)
- Testing
- Supervised digital training with focus on core stability, Supervised digital training with focus on aerobic exercise, Non-supervised daily physical activity
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Vastra Gotaland Region
End-stage Liver Disease, Liver Cirrhosis
Nutrition and Exercise Prehabilitation in Patients Awaiting Liver Transplantation
This study aims to evaluate the effects of a diet with even protein distribution plus exercise (Group A) versus a diet with skewed protein distribution plus exercise (Group B) versus standard dietary and physical activity advice…
- Conditions
- End-stage Liver Disease, Liver Cirrhosis, Liver Transplantation, Malnutrition
- Trial name
- POWER-LT (NCT07561138)
- Testing
- Diet with even protein distribution plus exercise program, Diet with skewed protein distribution plus exercise program, Standard dietary and physical activity advice
- Where
- 2 sites in Greece
- Volunteers
- 90 people
- Sponsor
- Kalliopi Anna Poulia
Paroxysmal AF, Treatment Decisions
Comparative Efficacy of 100-, 200-, & 400-mg Amiodarone in Patients With Paroxysmal AF Depending on Plasma Concentration
Amiodarone is a highly effective drug for the treatment and prevention of arrhythmias. In the 1970s and 1980s, numerous experimental and clinical studies comprehensively examined the mechanisms of amiodarone's antiarrhythmic…
- Conditions
- Paroxysmal AF, Treatment Decisions, Therapeutic Drug Monitoring (TDM)
- Trial name
- AMIODETECT (NCT07487714)
- Testing
- Pharmacotherapy with amiodarone 200 mg per day, Treatment with Amiodarone at a dose 100 mg per day, Treatment with Amiodarone at a dose 400 mg per day
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Polyneuropathy, Breast Cancer
A New Cancer Rehabilitation Process for Chemotherapy-Induced Foot Neuropathy Using Orthopedic Devices
The goal of this clinical study is to evaluate a new process for assessing and alleviating chemotherapy-induced peripheral neuropathy in the feet in patients treated with chemotherapy for early stage breast cancer.
- Trial name
- FOTNEV (NCT06904989)
- Testing
- Silicone orthosis, Standard Treatment
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Vastra Gotaland Region
Low Back Pain, Chronic
Person-Centered Lifestyle Redesign in Chronic Low Back Pain
This study is designed to examine the effects of a person-centered lifestyle intervention on pain, occupational performance, quality of life, disability, physical activity levels, and mental status in individuals with chronic low…
- Trial name
- NCT07163546
- Testing
- Lifestyle intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hacettepe University
Biliary Tract Cancer
Circulating Tumor Mitochondrial DNA (ct-mtDNA) As a Biomarker for Biliary Tract Cancer Recurrence Surveillance
This is a prospective, observational, single-center study. The purpose of this study is to evaluate the efficacy of circulating tumor mitochondrial DNA (ct-mtDNA) in plasma as a biomarker for minimal residual disease (MRD)…
- Trial name
- CCGLC-016 (NCT06653127)
- Testing
- Plasma and Tumor Tissue Mitochondrial DNA (mtDNA) Mutation Analysis
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tongji Hospital
Multiple Myeloma
Evaluation of a PREHABilitation Protocol Using Adapted Physical Activity (APA) for Multiple Myeloma Patients Eligible for Intensive Autologous Stem Cell Transplantation Treatment
Adapted physical activity for patients with haematological malignancies generally has positive effects on quality of life, fatigue and physical condition. However, some studies show little or no effect.
- Trial name
- PREHAB-APA (NCT06789003)
- Testing
- Adapted exercises, No intervention, Quality of Life questionnaire
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Henri Duffaut - Avignon
Diffuse Large B-Cell Lymphoma (DLBCL)
A Study to Evaluate the Impact of Mosunetuzumab Consolidation for Older Patients With Diffuse Large B-cell Lymphoma (DLBCL) Who Have Detectable Amounts of ctDNA (Circulating Tumor DNA) at the End of Treatment With Pola-R-mini-CHP
Older patients with diffuse large B- cell lymphoma (DLBCL) do not have the same rates of disease control as younger patients and are at risk for toxicity.
- Trial name
- GOLD (NCT06828991)
- Testing
- Mosunetuzumab, ClonoSEQ
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Danielle Wallace
Rehabilitation Programs
Exploring Physical Therapists and Wounded Soldiers' Perceptions Toward Integrating Emotional Elements Into Rehabilitation
This study aims to examine the perceptions, attitudes, and knowledge of physical therapists regarding the integration of emotional support into the rehabilitation of wounded soldiers.
- Trial name
- NCT07142109
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- University of Haifa
Hearing Loss, Adult-Onset, Tinnitus
AI-assisted Diagnosis, Triage and Assessment of Hearing Loss and Tinnitus
Hearing loss affects approximately 11 million people in the UK, while tinnitus impacts around 7 million. Both conditions can significantly reduce quality of life and are linked to poorer mental health and employment challenges.
- Trial name
- NCT07586098
- Testing
- Artificial Intelligence (AI) Assisted Clinical Decision Support Tool for managing Hearing Loss and Tinnitus
- Where
- United Kingdom
- Volunteers
- 1,500 people
- Sponsor
- Royal Cornwall Hospitals Trust
Supraspinatus Tendinitis
Anatomical Evaluation of Supraspinatus Through Ultrasonography and Biomechanical Measurements Following Blood Flow Restriction Therapy and Eccentric Exercise in Patients of Supraspinatus Tendinitis.
Patients of both gender groups with unilateral shoulder pain will be selected with age range 40-60 years from Sehat medical complex and randomly allocated into four groups (Group A, B, C and D) in Trial.
- Trial name
- NCT07873528
- Testing
- Blood flow restriction therapy, Eccentric Training, BFRT +ET
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sehat Medical Complex
Neovascular Age-related Macular Degeneration (nAMD), Diabetic Macular Edema (DME), Retinal Vein Occlusion (RVO)
DATA-INSIGHT is a Project That Looks at Health Data in Germany to Find Out How Many Patients Suffer From Eye Disease. The Project Also Explores New Ways to Collect and Use Publicly Available Healthcare Information.
The main goal of this study is to find out how common certain eye diseases are in Germany and how they have changed over time. The diseases being studied are: nAMD (neovascular age-related macular degeneration): a condition that…
- Trial name
- NCT07308639
- Testing
- anti-VEGF medication
- Where
- Germany
- Volunteers
- 50,000 people
- Sponsor
- Bayer
Primary Dental Caries
Detection of Residual Caries on Class II Cavity Walls in Primary Teeth Following Atraumatic Restorative Treatment (ART)
The primary aim of this study is to compare the diagnostic agreement and effectiveness of three different methods-Fluorescence-Aided Caries Excavation (FACE), caries detection dye, and clinical observation-in detecting residual…
- Trial name
- NCT07250022
- Testing
- FACE + Caries Detection Dye, FACE + Visual-Tactile Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University