Clinical trials: Photoprotection
Pigmentation, Redness
Photoprotection Efficacy With Sunscreen Formulas Containing the Cyclic Merocyanine Long-UVA Absorber MCE Under UV Day Light Exposure
To evaluate the photo-protector effect of BC_3 (E212657) formulated in SPF compared to SPF alone on UV Day Light induced pigmentation in healthy volunteers
- Trial name
- NCT04866797
- Testing
- cyclic merocyanine
- Where
- Romania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Photoaging, Photodamage
Randomised Controlled Trial of an Antioxidant and Sunscreen Combination Cream for Reducing DNA Damage in Human Skin
This randomized, double-blind, vehicle-controlled clinical trial investigates whether daily use of an encapsulated SPF 50 formulation containing a multi-antioxidant complex provides greater mitochondrial DNA (mtDNA) protection in…
- Conditions
- Photoaging, Photodamage, Mitochondrial Damage, Sunscreen
- Trial name
- NCT07301515
- Testing
- Antioxidant + Sunscreen Cream
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Klira Skin
Ultraviolet-Induced Change in Normal Skin
UVA Protection Factors of SPF 50 and 50+ Face Sunscreens
The goal of this observational study is to use the International Organization for Standardization (ISO) 24442:2011 in vivo method for assessment of the Ultraviolet A Protection Factor (UVAPF) of topical sunscreen products in…
- Trial name
- NCT06068010
- Where
- 6 sites in Brazil, France and 2 more
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Sunscreen Sensitivity, Ultraviolet-Induced Change in Normal Skin
Photoprotection Efficacy With Sunscreen Formulas Containing the Cyclic Merocyanine Long-UVA Absorber MCE Under Long-UVA Exposure.
To evaluate the photo-protector effect of BC_3 (E212657) formulated in SPF compared to SPF alone on long-UVA induced pigmentation in healthy volunteers.
- Trial name
- NCT04865120
- Testing
- cream cyclic merocyanine
- Where
- Romania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Efficacy of Sunscreen Products, Healthy Back Skin
Evaluation of the Photoprotection Efficacy with Sunscreen Formulas Under Visible Light Exposure
To evaluate the protective effect of three sunscreens on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.
- Conditions
- Efficacy of Sunscreen Products, Healthy Back Skin, Pigmentation Induced by Visible Light Exposure
- Trial name
- NCT06803901
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Polymorphic Light Eruption
Sunscreen and After-sun-lotion Protection in Polymorphic Light Eruption
Polymorphic light eruption (PLE) is a common photodermatosis characterized by the appearance of itching, erythema, papules or vesicles on sun-exposed skin.
- Trial name
- NCT00549588
- Testing
- After-sun-lotion with DNA repair enzymes, SPF30 sunscreen, Intervention: none (only UV)
- Where
- Austria
- Volunteers
- 14 people
- Sponsor
- Medical University of Graz
Vitiligo, PHOTOPROTECTION
Photoprotection Habits in Patients With Vitiligo
Intro: Patients with vitiligo have a reduced protection on depigmented areas. To date, however, little is known about photoprotection habits in patients with vitiligo even though these patients are thought to have a decreased…
- Conditions
- Vitiligo, PHOTOPROTECTION, SUN-EXPOSITION, FITZPATRICK SCALE
- Trial name
- VITISUN (NCT03323125)
- Testing
- Self-Assessment Questionnaire
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Actinic Keratoses, Carcinoma, Squamous Cell
Phase II AK Study in Organ Transplant Patients
The purpose of this study is to determine whether afamelanotide (CUV1647) is effective in reducing the number of actinic keratoses and squamous cell carcinomas developing in immune compromised organ transplant recipients, who are…
- Conditions
- Actinic Keratoses, Carcinoma, Squamous Cell, Organ Transplant Recipients
- Trial name
- NCT00829192
- Testing
- Afamelanotide (CUV1647)
- Where
- 12 sites in Australia, Belgium and 5 more
- Volunteers
- 200 people
- Sponsor
- Clinuvel Pharmaceuticals Limited
Visible Light Exposure on Healthy Back Skin
Determine the Photoprotection Efficacy of Seven Sunscreen Products Under Visible Light Exposure.
To evaluate the protective effect of seven sunscreens on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.
- Trial name
- NCT06796179
- Testing
- Visible Light Exposure - Treated zones with sunscreen products, Visible Light Exposure - Untreated zone
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Visible Light Exposures on Healthy Back Skin
Photoprotection Efficacy of a Sunscreen Under Visible Light Exposure by Using Two Different Simulators
To assess the ability of a protected agent to prevent the pigmentation under visible light exposures (VL) using two different simulators in healthy volunteers
- Trial name
- NCT06796140
- Testing
- Visible Light Exposure - Treated zone - Left hemi-back, Visible Light Exposure - Treated zone - Right hemi-back, Visible Light Exposure - Untreated zone - Left hemi-back
- Where
- Romania
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Study the Protection Potency of Sunscreen Products Against Pigmentation Induced by Visible Light Exposure on Healthy Back Skin
Evaluate the Photoprotection Efficacy of Sunscreen Formulas Under Visible Light Exposure
To evaluate the protective effect of three sunscreens on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.
- Trial name
- NCT06796192
- Testing
- Visible Light Exposure - Treated zones, Visible Light Exposure - Untreated zone
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Efficiency of Agents, Against Pigmentation Induced by Visible Light Exposures
Photoprotection Efficiency with Sunscreen Formulas Under Visible Light Exposure.
To evaluate the protective effect of three Laboratoire VICHY formulations on the pigmentation caused by visible light in comparison to a non-treated control zone in healthy volunteers
- Trial name
- NCT06827392
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Xeroderma Pigmentosum
XPAND Trial: Enhancing XP Photoprotection Activities - New Directions
People with Xeroderma Pigmentosum (XP) have a genetic condition which stops their skin repairing damage from Ultraviolet Radiation (UVR). This means they are much more likely to develop potentially fatal skin cancers.
- Trial name
- XPAND (NCT03445052)
- Testing
- XPAND
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust