Clinical trials: Pharmacogenomic Drug Interaction
Pharmacogenomic Drug Interaction
Trial of Precision Medicine in Emergency Departments
The objectives of this study are to (1) test the feasibility of the clinical implementation of preemptive pharmacogenetic (PGx) testing in the emergency department (ED) and (2) determine if PGx testing (with appropriate decision…
- Trial name
- TOPMEDs (NCT06448091)
- Testing
- Panel-based pharmacogenetic genotyping
- Where
- 3 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Florida
Pharmacogenomic Drug Interaction, Side Effect of Drug
Pharmacogenetic Panel to Prevent Adverse Drug Reactions in Daily Primary Care Practice:
The purpose of this study is to determine whether the implementation of pre-emptive pharmacogenomic (PGx) testing of a panel of clinically relevant PGx markers, to guide the dose and drug selection for 39 commonly prescribed…
- Conditions
- Pharmacogenomic Drug Interaction, Side Effect of Drug, Ineffective Drug Action, Drug Metabolism, Poor, CYP2D6-Related
- Trial name
- PREPARE-Mayo (NCT06322238)
- Testing
- PGx panel test
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Contraception, Pharmacogenomic Drug Interaction
Oral Contraceptive Pill (OCP) Pharmacogenomics
The goal of this clinical trial is to evaluate how differences in specific parts of our DNA can influence how individual bodies break down the hormones contained within oral contraceptive pills, which could affect how well these…
- Trial name
- NCT06334315
- Testing
- Desogestrel / Ethinyl Estradiol Pill
- Where
- 2 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Yale University
Healthy Volunteers, Aerosol Therapy
Inhaled Dose Analysis Using a Breath Actuated Nebulizer in Healthy Subjects
The goal of this crossover study is to compare urine drug concentrations using a continuous vibrating mesh nebulizer versus a breath-actuated vibrating mesh nebulizer in healthy volunteers.
- Conditions
- Healthy Volunteers, Aerosol Therapy, Inhaled Drug Dose, Pharmacogenomic Drug Interaction
- Trial name
- NCT06157515
- Testing
- Breath-actuated vibrating mesh nebulizer, Continuous vibrating mesh nebulizer
- Where
- Taiwan
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Influence of Genotype of Drug Metabolizing Enzyme or Transporter on the Pharmacokinetics/Pharmacodynamics of Clopidogrel, Influence of Aspirin on the Pharmacokinetics/Pharmacodynamics of Clopidogrel
Clinical Trial to Evaluate the Influence of Genotype on the Pharmacokinetics/Pharmacodynamics of Clopidogrel
This study has an open-label, five-period, single-sequence design. The purpose of this study is as follows; 1. Primary To evaluate the influence of genotype of drug metabolizing enzyme or transporter on the…
- Trial name
- NCT01503658
- Testing
- Clopidogrel+Aspirin
- Where
- South Korea
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital