Clinical trials: Perturbation
Alzheimer Disease
Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease
The researchers are trying to determine whether ovarian hormones are associated with aging processes and with the risk of developing Alzheimer's disease in women.
- Trial name
- SEED-AD (NCT03821857)
- Testing
- 18-F-Flortaucipir
- Where
- 2 sites in United States
- Volunteers
- 614 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Balance, Postural, Prevention, Accident
Effect of Adaptive Training for Balance Recovery
The long-term objective of this research is a prophylactic approach that can reduce the incidence of falls and the resulting injuries among older adults at risk and thus reduce its escalating medical cost.
- Trial name
- NCT02126488
- Testing
- treadmill slip perturbation, observation training
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Neurodevelopmental Disorder (Diagnosis)
NEOnatal Multiexposure to Medical Devices Plasticizers: Endocrine Disruption MIXture Effects and Neurodevelopmental Disorders
The goal of this observational study is to evaluate the neurodevelopment of children from the ARMED NEO cohort through the ASQ3 score.
- Trial name
- NEOMIX WP3 (NCT06726824)
- Where
- 2 sites in France
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Daily Sedative Interruption, Sedation Strategies
Pilot Study for Sedation Interruption in Children
The purpose of this study is to estimate the hypothesized benefit of sedation interruption protocol on mechanical ventilation duration and PICU length of stay.
- Conditions
- Daily Sedative Interruption, Sedation Strategies, Sedation Protocols, Mechanical Ventilation
- Trial name
- NCT02426320
- Testing
- Sedation Interruption Protocol, Standard Sedation Protocol
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Davinia Withington
Atrial Fibrillation, Venous Thromboembolism
Perioperative Anticoagulant Use for Surgery Evaluation Emergency Registry
Among patients who are receiving long-term anticoagulant therapy, whether with a direct oral anticoagulant (DOAC) or vitamin K antagonist (VKA), approximately 3-5% who require treatment interruption for a surgery will do so in an…
- Conditions
- Atrial Fibrillation, Venous Thromboembolism, Arterial Vascular Disease
- Trial name
- PAUSE-ER (NCT04195113)
- Where
- 3 sites in Canada
- Volunteers
- 242 people
- Sponsor
- McMaster University
Corneal Epithelial Disruption, Corneal Staining
Evaluation of Corneal Staining With Various Contact Lens/Solution Combinations
The purpose of this study is to quantify the amount of corneal staining observed with various marketed contact lens/multipurpose solution combinations.
- Trial name
- NCT00381446
- Testing
- Marketed contact lens care products
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Andrasko, Gary, OD, LLC
Atrial Fibrillation (AF)
Perioperative Anticoagulant Use for Surgery Evaluation -Virtual Visit (PAUSE-Virtual)
The purpose of the PAUSE-Virtual Study is to show that by changing pre-surgery visits with patients taking a blood thinner (direct oral anticoagulant (apixaban, dabigatran, edoxaban, rivaroxaban or warfarin) when the participant…
- Trial name
- PAUSEVirtual (NCT06844227)
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 1,780 people
- Sponsor
- McMaster University
Fall Prevention
Perturbation Training Compared to Balance and Strengthening Exercise, for Elderly at Risk of Falling
One third of adults over 65 and 50% of adults above 80 years old fall at list once a year. In some cases, falls result in fractures, hospitalization, functional limitations, depression, morbidity and mortality.
- Trial name
- NCT04228159
- Testing
- Balance Tutor Biofeedback Rehabilitation System, Balance and strengthening exercise
- Where
- 3 sites in Israel
- Volunteers
- 250 people
- Sponsor
- Clalit Health Services