Clinical trials: Personality Disorder, Borderline
Borderline Personality Disorder BPD
Characterization of the Neural Bases of Mental Imagery in Individuals With Borderline Personality Disorder: An EEG Study
Borderline Personality Disorder (BPD) involves altered social cognition, notably dysfunctional processing of cues signaling potential social exclusion and heightened social pain.
- Trial name
- BABO (NCT07428200)
- Testing
- 2 Tasks : - stop signal reaction time and Cyberball then ill out an evaluation form
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Borderline Personality Disorder
The BRIDGE Project
The BRIDGE project: A feasibility randomised controlled trial of brief, intensive assessment and integrated formulation for young people (age 14-24) early in the course of borderline personality disorder.
- Trial name
- BRIDGE (NCT05023447)
- Testing
- BRIDGE Intervention, Service as Usual
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- NHS Greater Glasgow and Clyde
Borderline Personality Disorder, Post-Traumatic Stress Disorders
Outcome of Crisis Intervention for Subjects With Borderline Personality Disorder or Post-Traumatic Stress Disorder
Dr. Laddis will test a hypothesis about the nature and the management of behavioral crises in patients with borderline personality disorder (BPD) or post-traumatic stress disorder (PTSD).
- Trial name
- NCT00269139
- Testing
- Crisis resolution
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Laddis, Andreas, M.D.
Borderline Personality Disorder (BPD)
Internal Family Systems Therapy for Borderline Personality Disorder
Borderline Personality Disorder (BPD) involves intense emotional ups and downs, unstable relationships, impulsivity, and a poor sense of self.
- Trial name
- IFS for BPD (NCT07342907)
- Testing
- Internal family systems therapy
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Waypoint Centre for Mental Health Care
Borderline Personality Disorder
Stress & Social Cognition in Borderline Personality Disorder
The investigators will examine whether perceived social exclusion provoke a reduction in prosocial behavior in BPD patients.
- Trial name
- SOKO-1 (NCT04504994)
- Testing
- inclusion condition
- Where
- Germany
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Posttraumatic Stress Disorders, Borderline Personality Disorders
A Randomized Control Trial of Narrative Exposure Therapy Versus Treatment as Usual in the Therapy of Borderline Personality Disorder
Definition of the efficacy of NET compared with "treatment as usual" in the treatment of patients with complex traumatic disease (borderline personality disorder (BPD) and posttraumatic stress disorder (PTSD)) as assessed by…
- Trial name
- NET (NCT01033708)
- Testing
- narrative exposure therapy
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Zentrum für Integrative Psychiatrie
Parent-child Problem, Borderline Personality Disorder
Supportive Program for Mother With BPD
Borderline Personality Disorder (BPD) is characterized by a pervasive pattern of instability of interpersonal relationships, self-image and emotions as well as marked impulsivity.
- Trial name
- PAM-B (NCT02203708)
- Testing
- Supportive Program for Mother with BPD (SuPMother-B).
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Toulouse
Borderline Personality Disorder, Oxytocin
Interplay Between Oxytocin and Cortisol During Stress in Borderline Personality Disorder
This study aims to determine the feasibility and preliminary data on the interaction between oxytocin and cortisol during stress in borderline personnality disorder.
- Trial name
- OXT-CORT-BPD (NCT05357521)
- Testing
- stress test
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Borderline Personality Disorder
Botulinum Toxin A for Emotional Stabilization in Borderline Personality Disorder (BPD)
The main objective of the trial is to test whether a single application of botulinum toxin A into the glabellar region will lead to emotional stabilization in borderline personality disorder through paralysis of facial…
- Trial name
- BTX-BPD (NCT02728778)
- Testing
- incobotulinumtoxin A, Acupuncture
- Where
- 2 sites in Germany
- Volunteers
- 54 people
- Sponsor
- Hannover Medical School
Major Depressive Episode, Borderline Personality Disorder
Circuit-Based Approach to Suicide: Biomarkers, Predictors, and Novel Therapeutics
This neuroimaging study is a clinical trial investigating the effectiveness of intermittent theta-burst transcranial magnetic stimulation (iTBS-TMS) to the inferior parietal lobule (IPL) in reducing suicide risk in patients with…
- Conditions
- Major Depressive Episode, Borderline Personality Disorder, Suicide
- Trial name
- NCT04130958
- Testing
- Intermittent Theta Burst Transcranial Magnetic Stimulation (Active)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Massachusetts General Hospital
Diagnosis, Dual (Psychiatry)
Efficacy of Animal-assisted Therapy in Patients With Borderline Personality Disorder and Addictions.
Animal-assisted therapy (AAT) is a complementary intervention of therapy that has shown positive results in the treatment of various pathologies.
- Trial name
- NCT05115266
- Testing
- Animal-assisted therapy (AAT, Usual treatment
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Miguel Monfort Montolio
Borderline Personality Disorder, Eating Disorders
Chrysalis Day Program Body Mass Index Study
This is a study to determine if the approach taken to treat patients in the Chrysalis Day Hospital Program will favourably effect their health status as assessed by Body Mass Index (BMI)
- Trial name
- NCT00202215
- Testing
- Chrysalis Day Program
- Where
- Canada
- Volunteers
- 106 people
- Sponsor
- Queen's University
Borderline Personality Disorder
Personality Change Study for Borderline Personality Disorder
Participants with borderline personality disorder will undergo an a 2 - 4 week baseline assessment to determine level of outcomes of interest in the absence of treatment.
- Trial name
- NCT06005129
- Testing
- Personality-Based Therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)
The goal of this clinical trial is to learn if intravenous (IV) ketamine with Dialectical Behavioural Therapy (DBT) reduces suicidal ideation in individuals with suicidality who have been diagnosed with Borderline Personality…
- Conditions
- Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder, Treatment-resistant Bipolar Depression, Major Depressive Disorder (MDD)
- Trial name
- KET-DBT (NCT07569198)
- Testing
- Ketamine Hydrochloride, Midazolam Hydrochloride, Dialectical Behavioral Therapy (DBT)
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Joshua Rosenblat
Borderline Personality Disorder, Trauma
DBT Skills Plus EMDR for BPD and Trauma
Borderline Personality Disorder (BPD) is a severe disorder that frequently co-occurs with post-traumatic stress disorder (PTSD). The comorbidity of BPD and PTSD is more disabling, predicting lower rates of BPD remission.
- Trial name
- TT-BPD (NCT04856449)
- Testing
- Dialectical Behavioral Therapy Skills Training, EMDR
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Family Caregivers
The Impact of a Psycho-educational Program for Family Members of Individuals With Borderline Personality Disorder
This is a prospective, single-arm, open-label study to assess the impact of the Family Connections (FC) program on various factors including burden, grief and several clinical variables (i.e., depressive symptoms, family…
- Trial name
- NCT06074289
- Testing
- Family connections program
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Borderline Personality Disorder
Transcranial Magnetic Stimulation for Borderline Personality Disorder
Primary purpose : to assess the effect on neuropsychological tasks related to planning of 10 daily sessions of right dorsolateral prefrontal cortex with High-frequency repetitive transcranial magnetic stimulation (rTMS) on…
- Trial name
- SiMaT-B (NCT01076933)
- Testing
- repetitive Transcranial Stimulation Magnetic (rTMS)
- Where
- France
- Volunteers
- 13 people
- Sponsor
- University Hospital, Toulouse
Borderline Personality Disorder
Impulsivity With Borderline Personality Disorder/tMS
This is a prospective, randomized, double-blind, parallel-group controlled trial. The aim of this research project is to compare the clinical benefits achieved in patients with Borderline Personality Disorder (BPD) following two…
- Trial name
- IMPULSE (NCT05942651)
- Testing
- Non-invasive brain stimulation protocol (Cortico-cortical paired associative stimulation protocol (ccPAS)) delivered at 4 ms intervals., Non-invasive brain stimulation protocol (Cortico-cortical paired associative stimulation protocol (ccPAS)) delivered at 100 ms intervals
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hôpital le Vinatier
Borderline Personality Disorder
The Effect of Oxytocin Administration on Interpersonal Cooperation in Borderline Personality Disorder Patients and Healthy Adults
The study will examine behavioral patterns and underlying neural correlates which distinguish patients with borderline personality disorder (BPD) from healthy subjects as they participate in a two-person trust game and will…
- Trial name
- NCT02225600
- Testing
- 40 IU Intranasal Oxytocin, 24 IU intranasal Oxytocin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Borderline Personality Disorder
Quetiapine Treatment for Symptoms Associated With Borderline Personality Disorder
Objective: The objective of this study is to quantitatively examine the efficacy of Seroquel (active ingredient quetiapine fumarate) in subjects with Borderline Personality Disorder (BPD).
- Trial name
- NCT00122070
- Testing
- Quetiapine Fumarate
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Dentistry of New Jersey