Clinical trials: Personality
Psychological Distress, Type D Personality
Efficacy of Acceptance and Commitment Therapy for the Management of Quality of Life in Patients Post Myocardial Infarction
The present study aims to investigate the efficacy of acceptance and commitment therapy for the management of quality of life in patients post-myocardial infarction
- Conditions
- Psychological Distress, Type D Personality, Medication Adherence, Quality of Life
- Trial name
- NCT06548282
- Testing
- Acceptance and commitment therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Fatima Jinnah Women University
Borderline Personality Disorder
Study to Test the Efficacy and Safety of Vafidemstat in Adult Borderline Personality Disorder Population
PORTICO is a Phase IIb study to evaluate the efficacy and safety of vafidemstat in an adult borderline personality disorder (BPD) population.
- Trial name
- NCT04932291
- Testing
- vafidemstat
- Where
- 21 sites in United States, Bulgaria and 3 more
- Volunteers
- 211 people
- Sponsor
- Oryzon Genomics S.A.
Borderline Personality Disorder
Treating Suicidal Behavior and Self-Mutilation in People With Borderline Personality Disorder
This study will determine whether dialectical behavior therapy and fluoxetine are more effective combined or alone in treating people with borderline personality disorder.
- Trial name
- NCT00533117
- Testing
- Fluoxetine, Dialectical Behavior Therapy, Supportive psychotherapy
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- New York State Psychiatric Institute
Hyperacusis
Cognitive Behavioral Therapy for Hyperacusis
The main purpose of this study is to investigate whether cognitive behaviour therapy (CBT) can be useful for people suffering from Hyperacusis.
- Trial name
- NCT01321814
- Testing
- Cognitive behavioural therapy
- Where
- Sweden
- Volunteers
- 62 people
- Sponsor
- Linkoeping University
Borderline Personality Disorder, Mothers
Parenting Skills for Mothers With Borderline Personality Disorder (BPD)
The first disorder-specific parenting training program for mothers with Borderline Personality Disorder (M-BPD) is evaluated in a randomized controlled trial.
- Trial name
- ProChild (NCT04169048)
- Testing
- Group training for mothers with Borderline Personality Disorder
- Where
- Germany
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Freie Universität Berlin
Anxiety, Somatoform Disorders
Evaluating the Cost Effectiveness of ISTDP: A Quasi Experimental Study
Objective: To evaluate whether or not cases treated with Intensive Short-term Dynamic Psychotherapy (ISTDP) facilitate healthcare cost reduction, whether any observed reduction is greater than that of a control group and whether…
- Conditions
- Anxiety, Somatoform Disorders, Personality Disorders, Depression
- Trial name
- CEISTDP (NCT01924715)
- Testing
- ISTDP
- Where
- Canada
- Volunteers
- 1,082 people
- Sponsor
- Nova Scotia Health Authority
Stress Disorders, Traumatic, Depressive Disorder
The Immune System and Psychiatric Disorders
The study is based on a hypothesis that there is interaction between the activity in the immune system and in the mind. To study this, the investigators register different measures for activity in the immune system on patients…
- Conditions
- Stress Disorders, Traumatic, Depressive Disorder, Bipolar Disorder, Personality Disorders
- Trial name
- NCT00184418
- Where
- Norway
- Volunteers
- 1,400 people
- Sponsor
- Norwegian University of Science and Technology
Psychopathic Personality Trait, Conduct Disorder
The Efficacy of a Compassion Focused Therapy-based Intervention in Detained Youth
This non-randomized controlled trial with a control group aimed to assess the efficacy of a 20-session individualized Compassion Focused Therapy-based intervention, the PSYCHOPATHY.COMP, in reducing psychopathic traits (primary…
- Conditions
- Psychopathic Personality Trait, Conduct Disorder, Delinquency
- Trial name
- PSYCOMP (NCT03971682)
- Testing
- PSYCHOPATHY.COMP program., Treatment As Usual - TAU
- Where
- Portugal
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Schizotypal Personality Disorder
Compassion and Metacognition in Schizotypal Personality
The purpose of this study is to assess the safety and efficacy of a newly developed psychotherapy for schizotypal personality disorder.
- Trial name
- CMBT (NCT04764708)
- Testing
- Compassion and Metacognition Based Therapy, Cognitive Behavioral Therapy
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Tages Onlus
Self-Harm, Deliberate, Borderline Personality Disorder
Dialectical Behavior Therapy vs Enhanced Usual Care for Suicidal and Self-harming Adolescents. 10 Year Follow-up
The purpose of the study is to evaluate the long-term efficacy of dialectical behavior therapy (DBT) in treatment of adolescents with deliberate self harm compared to enhanced usual care (EUC).
- Trial name
- NCT04298190
- Testing
- Dialectical Behaviour Therapy for Adolescents (DBT-A), Enhanced usual care
- Where
- Norway
- Volunteers
- 61 people
- Sponsor
- Oslo University Hospital
Emotional Instability Personality Disorder (Borderline Personality Disorder), Attention Deficit Hyperactivity Disorder
Emotional and Non-emotional Regulation in Patients With Emotional Instability and ADHD
The purpose of this study is to investigate how emotional and non-emotional regulation processes differ in EIP patients (with different levels of ADHD symptoms/ADHD-comorbidity) compared to controls.
- Conditions
- Emotional Instability Personality Disorder (Borderline Personality Disorder), Attention Deficit Hyperactivity Disorder, Healthy Controls
- Trial name
- NCT02797873
- Testing
- fMRI - Stroop task, fMRI - MID task, Stop Signal Task
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Prodromal Schizophrenia
Investigating the Role of Diazepam on Brain Function and Chemistry in Psychosis Risk
This study will investigate whether a single dose of diazepam (5mg) compared to placebo can modulate brain chemistry (GABA/glutamate levels) and function (blood flow, neural response and connectivity during tasks and at-rest) in…
- Trial name
- BENZOGAP (NCT06190483)
- Testing
- Diazepam 5 Mg Oral Tablet, Ascorbic Acid 50 Mg Oral Tablet
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- King's College London
Personality Disorders
Evaluating Adapted Structured Clinical Management for People With a Diagnosis of Personality Disorder
Camden and Islington NHS Foundation Trust in London has a Personality Disorder Service (PDS) which offers a number of evidence-based interventions to people with a diagnosis of Personality Disorder.
- Trial name
- NCT04207970
- Testing
- Adapted Structured Clinical Management
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- Camden and Islington NHS Trust
Prediabetes, Hyperglycemia
Personality Traits and Biochemical Risk Phenotypes
This prospective observational study investigates the association between personality traits and routine laboratory abnormalities in adults undergoing routine health assessment.
- Conditions
- Prediabetes, Hyperglycemia, Metabolic Syndrome
- Trial name
- PHEBiP (NCT07653048)
- Where
- Romania
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Medical Center TOPMED
Schizophrenia, Schizoaffective Disorder
Accelerated TMS in Psychosis
This study is to determine the tolerability and efficacy of an accelerated schedule of Transcranial Magnetic Stimulation for treating symptoms of psychotic disorders such as schizophrenia.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Prodromal Schizophrenia
- Trial name
- ATP (NCT05567848)
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Beth Israel Deaconess Medical Center
Personality
Personality and Drug Use (PDU)
The study aims to assess whether the use of drugs relates to personality ratings. Specifically, we plan to investigate if people with different histories of substance use differentiate on personality assessments (current and…
- Trial name
- PDU (NCT05180149)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Quantified Citizen Technologies Inc.
Antisocial Personality Disorder
Positive Psychotheraphy and Antisocial Personality Disorder: Crime, Aggression, Anger
Studies on Antisocial Personality Disorder (ASPD), in which criminal behaviors, aggression and anger behaviors are frequently seen, are very rare.
- Trial name
- NCT04903938
- Testing
- Primary And Secondary Abilities Among The Individuals With Antisocial Personality Disorder Within The Scope Of Positive Psychotherapy: Their Relationship With Criminal Behaviors, Aggression And Anger
- Volunteers
- 3 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Borderline Personality Disorder
Five Factor Model Treatment for Borderline Personality Disorder
The primary purpose of this study is to explore acceptability, feasibility, and preliminary efficacy of a novel cognitive-behavioral treatment for borderline personality disorder (BPD).
- Trial name
- NCT04587518
- Testing
- Personality-Based Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Alcohol Use, Drug Use
Effectiveness of Take it Personal!
A controlled pre-post design study on Take it Personal! has demonstrated effectiveness in reducing the frequency and severity of youth use of alcohol, cannabis or other illicit drugs.
- Conditions
- Alcohol Use, Drug Use, Mild Intellectual Disability, IQ 50-70, Borderline Intellectual Disabilities (Intelligence Quotient 70-85)
- Trial name
- NCT05843474
- Testing
- Take it Personal!
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Behavioural Science Institute
Alcohol Abuse, Drug Abuse
Adventure: Teacher Delivered Personality-targeted Interventions for Substance Misuse
Several personality factors have been shown to be associated with risk for alcohol and substance misuse, and differentiate substance abusers based on clinical profile, treatment response and susceptibility to other forms of…
- Conditions
- Alcohol Abuse, Drug Abuse, Depression, Panic Disorder
- Trial name
- Adventure (NCT00776685)
- Testing
- Personality-targeted interventions
- Where
- United Kingdom
- Volunteers
- 3,190 people, healthy volunteers welcome
- Sponsor
- King's College London