Clinical trials: Persistent Postoperative Pain
Knee Arthropathy
Persistent Post Surgical Pain After Total Knee Arthroplasty
Patients undergone total knee replacement are randomized to receive a "fast track" regional anesthesia protocol or a "traditional" regional anesthesia continuous infusion by both a femoral and sciatic catheter to assess if this…
- Trial name
- NCT06182059
- Testing
- continuous peripheral nerve block
- Where
- Italy
- Volunteers
- 436 people
- Sponsor
- Policlinico di Monza SpA
Pain, Postoperative, Root Resorption
Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair
Management of non-vital primary molars is challenging due to the natural anatomy of primary teeth, patients' young age, and their behavior toward dental treatment.
- Conditions
- Pain, Postoperative, Root Resorption, Persistent Infection, Necrotic Pulp
- Trial name
- NCT06926322
- Testing
- Conventional double antibiotic paste of Metronidazole 500 mg plus Ciprofloxacin 500 mg mixed with propylene glycol, Double antibiotic paste of Metronidazole and Ciprofloxacin loaded chitosan-coated silver nanoparticles, chitosan-coated silver nanoparticles
- Where
- Egypt
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Breast Cancer, Survivorship
Dance Study for Post-surgical Pain in Breast Cancer Survivors
The purpose of this study is to examine how a 12-week, virtual dance program may improve pain and quality of life in participants with persistent post-surgical pain, or PPSP, following mastectomy or lumpectomy.
- Conditions
- Breast Cancer, Survivorship, Pain, Postoperative
- Trial name
- NCT06758102
- Testing
- Dance Program
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Regional Anesthesia Morbidity, Pain, Postoperative
Efficacy of Ultrasound Guided ESP Vs Video-assisted PVB Catheter Placement in Minimally Invasive Thoracic Surgery
Minimally Invasive Thoracic Surgery (MITS) is a surgical method used to perform lung surgery through small incisions between the ribs and includes both Video-Assisted Thoracic Surgery (VATS) and Robotic assisted Thoracic Surgery…
- Conditions
- Regional Anesthesia Morbidity, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT04729712
- Testing
- Anaesthesiologist-administered ultrasound guided Erector Spinae block with catheter insertion, Surgeon-administered video-assisted Paravertebral block with catheter insertion
- Where
- 2 sites in Ireland
- Volunteers
- 80 people
- Sponsor
- Mater Misericordiae University Hospital
Persistent Postsurgical Pain, Breast Cancer Female
Preventing Persistent Pain and Reducing Depressive and Anxious Symptoms Following Mastectomy and Lumpectomy
The proposed study will be a pilot randomized controlled trial comparing treatment as usual (TAU) to treatment as usual plus a brief Acceptance and Commitment Therapy (ACT) intervention (TAU + ACT) with mastectomy and lumpectomy…
- Conditions
- Persistent Postsurgical Pain, Breast Cancer Female, Ductal Carcinoma in Situ
- Trial name
- NCT03430765
- Testing
- Acceptance and Commitment Therapy
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Katherine Hadlandsmyth
Breast Cancer
Regional Anesthesia for Breast Surgery
Patients scheduled for mastecotmy will be randomized to receive either an ultrasound-guided double space paravertebral block or a PECSII + parasternal block.
- Trial name
- NCT03941223
- Testing
- PECSII and paravertebral blocks
- Where
- Italy
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Persistent Postsurgical Pain, Arthritis Hip
Persistent Pain After Hip Replacement
This study is a nationwide cross-sectional survey on pain and satisfaction after total hip arthroplasty (THA). Please find the full protocol uploaded on ClinicalTrials.gov
- Conditions
- Persistent Postsurgical Pain, Arthritis Hip, Neuropathic Pain, Opioid Use
- Trial name
- NCT05845177
- Testing
- Primary Total Hip Arthroplasty
- Where
- Denmark
- Volunteers
- 2,777 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Breast Neoplasms, Pain, Postoperative
Persistent Pain After Breast Cancer Treatment With Docetaxel
Breast cancer treatment is for many patients followed by sequelae, such as persistent pain, sensory disturbances, lymphedema and reduced physical function.
- Conditions
- Breast Neoplasms, Pain, Postoperative, Neuralgia, Lymphedema
- Trial name
- NCT01279018
- Volunteers
- 2,490 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Failed Back Surgery Syndrome
Subthreshold SCS or BMT
Given the substantial socioeconomic impact of Spinal Cord Stimulation (SCS) implantations and given that currently no direct high-quality evidence with a relevant outcome measurement is available to guide the treatment choice…
- Trial name
- TRADITION (NCT05169047)
- Testing
- Best Medical Treatment, Subthreshold Spinal Cord Stimulation
- Where
- 5 sites in Belgium
- Volunteers
- 114 people
- Sponsor
- Moens Maarten
Pain, Postoperative
Short and Long-term Effects of Surgical Repair of Pectus Deformities
A large number of institutions have reported their early results with minimally invasive repair of pectus excavatum and open repair of pectus carinatum, but only few have addressed the outcomes relevant to the concerns of the…
- Trial name
- NCT01329120
- Testing
- Minimally invasive repair of pectus excavatum, Open surgical repair of pectus carinatum
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- University of Aarhus
Knee Osteoarthritis
Painful Knee Prosthesis. Relationship Between Endogenous Analgesia and Persistent Post Surgical Pain.
This is a prospective, observational study, aimed to establish the relationship between an inefficient endogenous pain modulation before surgery (total knee arthroplasty; TKA) and the probability to develop chronic pain after…
- Trial name
- NCT01811888
- Testing
- Quantitative sensory testing (QST)
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Parc de Salut Mar
Breast Cancer, Mastectomy
A Study to Reduce Persistent Post-mastectomy Pain Using Opioid-free Anesthesia
In 230 patients undergoing mastectomy, the investigators will compare opioid-free anesthesia (OFA) versus conventional opioid-based anesthesia in terms of chronic pain.
- Conditions
- Breast Cancer, Mastectomy, Pain, Chronic, Pain, Post Operative
- Trial name
- RELIEF (NCT05146778)
- Testing
- Opioid-free anesthesia, Conventional opioid-based anesthesia
- Where
- South Korea
- Volunteers
- 230 people
- Sponsor
- Gangnam Severance Hospital
Pain, Postoperative
TEMporal PostOperative Pain Signatures
The purpose of this research study is to determine what causes pain after surgery to increase or decrease over time.
- Trial name
- TEMPOS (NCT02407743)
- Testing
- Surgical patients' clinical progression, Genetic markers
- Where
- United States
- Volunteers
- 428 people
- Sponsor
- University of Florida
Coping Skills Training for Persistent Post-Surgical Pain, General Health Education
Well-Being After Breast Cancer Surgery
The purpose of this study is to compare the benefits of skills training and health education interventions designed specifically to increase the well-being of people with persistent pain after breast surgery for lobular carcinoma…
- Trial name
- WB ABCs (NCT04225585)
- Testing
- CST-PSP, General health education
- Where
- 2 sites in United States
- Volunteers
- 316 people
- Sponsor
- Duke University
Sexual Dysfunction, Hernia, Inguinal
Pain Related Sexual Dysfunction After Laparoscopic Inguinal Hernia Repair
Previous studies have reported that about 3 % of patients who have had open inguinal herniorrhaphy had a visceral, ejaculatory-related pain.
- Conditions
- Sexual Dysfunction, Hernia, Inguinal, Other Chronic Postoperative Pain
- Trial name
- NCT01086007
- Where
- Denmark
- Volunteers
- 1,172 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Breast Cancer, Pain
Long Term Follow-up of Persistent Pain, Sensory Disturbances and Lymphedema After Breast Cancer Treatment
Persistent pain, sensory disturbances, lymphedema and functional impairment are frequently occurring late effects of breast cancer treatment.
- Conditions
- Breast Cancer, Pain, Post Operative Pain, Lymphedema
- Trial name
- NCT01543711
- Where
- Denmark
- Volunteers
- 2,411 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Amputation; Lower Extremity, Pain, Persistent Postsurgical
Altius Peripheral Nerve Stimulation in Amputees After TMR/RPNI
This is a single-center, prospective, within-subject study. This study seeks to enroll a total of 32 prospective subjects who will undergo surgical implantation of the FDA-approved Altius® system.
- Trial name
- NCT07571239
- Testing
- Surgical Implantation
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- NYU Langone Health
Breast Cancer, Chronic Pain
Evaluation And Risk Assessment For Persistent Postsurgical Pain After Breast Surgery
Pre-existing pain and severe postoperative pain are predictors of persistent pain after surgery, but a complete understanding on the development of persistent pain is still lacking.
- Conditions
- Breast Cancer, Chronic Pain, Acute Pain, Depression, Anxiety
- Trial name
- B-CAPP (NCT03408717)
- Testing
- Questionnaires, Mechanical Temporal Summation assessment, Pain threshold assessment
- Where
- 2 sites in United States, Singapore
- Volunteers
- 220 people
- Sponsor
- KK Women's and Children's Hospital
Postoperative Pain, Postherniotomy Pain
Neurophysiological Characterization of Postherniotomy Pain
Sensory function is different in persistent postherniotomy pain patients than in operated controls, suggesting this to be a neuropathic pain syndrome.
- Conditions
- Postoperative Pain, Postherniotomy Pain, Neuropathic Pain
- Trial name
- NCT00719368
- Where
- 2 sites in Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Neuropathic Pain
Cryoneurolysis for Cutaneous Neuropathic Pain
Feasibility study with 25 patients investigating the effect of cryoneurolysis on persistent cutaneous neuropathic pain after surgery and trauma. All patients receive active treatment (cryoneurolysis).
- Trial name
- NCT04911569
- Testing
- Cryoneurolysis
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Aarhus University Hospital