Clinical trials: Persistent Pain
Post Surgical Pain
Characterization of PostOp Pain in Shoulder and Knee Arthroscopy
The purpose of this study is to describe the chronology of post operative pain in patients undergoing total knee arthroplasty and total hip arthroplasty.
- Trial name
- PurpleRain (NCT03047434)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Pelvic Girdle Pain
Low Level Laser Therapy in Persistent Pelvic Girdle Pain
Persistent pregnancy-related pelvic girdle pain is common, 2-5% av all women given birth is suffering from disabling daily pain with high impact on quality of life.
- Trial name
- NCT02789735
- Testing
- Active laser therapy
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Uppsala University
Breast Cancer Female, Chronic Pain
Frequency and Presentations of Chronic Pain Following Breast Cancer Surgery: An Observational Study in a Tertiary Care Hospital of Pakistan
This study is designed to evaluate the frequency and presentations of chronic persistent pain in patients after breast cancer surgery at our tertiary care hospital.
- Trial name
- NCT03961269
- Volunteers
- 120 people
- Sponsor
- Ali Sarfraz Siddiqui
Chronic Pain, Chronic Pain Due to Injury
Virtual Pain Education for Spinal Cord Stimulation Patients
Chronic pain is a leading cause of disability in the United States. When standard treatments fail, many patients develop treatment resistant pain and undergo Spinal Cord Stimulation (SCS) therapy.
- Conditions
- Chronic Pain, Chronic Pain Due to Injury, Failed Back Syndrome, Persistent Spinal Pain Syndrome
- Trial name
- SCS-PNE (NCT07743905)
- Testing
- SCS-PNE intervention
- Volunteers
- 50 people
- Sponsor
- University of Arkansas
Musculoskeletal Inflammatory
ARTERIAL EMBOLIZATION OF PERSISTENT GENICULATE ARTERIES FOR CHRONIC PAIN MANAGEMENT AFTER TOTAL KNEE-REPLACEMENT ARTHROPLASTY(KNEE EMBOLISATION)
Recent works in interventional radiology have shown interesting results in the treatment of musculoskeletal inflammatory sites by arterial embolization. Supra-selective arterial embolization has been successfully developed by Dr.
- Trial name
- NCT04417686
- Testing
- arterial embolization
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Cannabinoid, Tetrahydrocannabinol
Efficacy Study of Δ9-THC to Treat Chronic Abdominal Pain
The main goal of this trial is to study the efficacy of Namisol® after a single dose of Δ9-THC in the treatment of pain resulting from chronic pancreatitis. Objective measures of pain processing, e.g.
- Conditions
- Cannabinoid, Tetrahydrocannabinol, Chronic Pancreatitis, Abdominal Pain
- Trial name
- Delta-pain (NCT01318369)
- Testing
- Namisol, Diazepam
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Radboud University Medical Center
Root Canal Therapy, Persistent Tooth Pain
DPBRN Persistent Pain and Root Canal Therapy
The purpose of this study is to document by survey the occurence of tooth pain present 3 months and 6 months after root canal therapy in the patients recruited for the DPBRN "Peri-operative tooth pain" study.
- Trial name
- NCT01201668
- Where
- 8 sites in United States, Denmark
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
Chronic Pain, Pelvic Pain
Evaluating the Efficacy of Intranasal Oxytocin Among Individuals With Persistent Pain
This study is a placebo-controlled, double-blind, within-participants crossover investigation of the effect of intranasal oxytocin on pain and function among women with chronic pelvic pain.
- Trial name
- NCT02888574
- Testing
- Intranasal Oxytocin
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Calgary
Herniated Disc, Sciatica
Intradiscal Discogel® in Resistant Sciatica
Sciatica due to herniated disc is a major cause of disability in young adults. Surgery is the gold-standard and the only controlled treatment in case of failure of conservative treatment.
- Conditions
- Herniated Disc, Sciatica, Persistent Pain, Leg
- Trial name
- EDIS (NCT02313350)
- Testing
- Chemonucleolysis with Discogel, open discectomy
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Fatigue, Lupus Erythematosus, Systemic
Acupressure for Fatigue in Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by involvement of multiple organs with a female to male ratio of 12:1 with the highest incidence reported in women of child bearing age (15-44…
- Conditions
- Fatigue, Lupus Erythematosus, Systemic, Pain, Chronic, Quality of Life
- Trial name
- AcuSLE (NCT03200548)
- Testing
- Relaxing acupressure plus usual care, Usual care, Stimulating acupressure plus usual care
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Suzanna Zick
Fybromyalgia
Interdisciplinary Therapeutic Intervention for People With Persistent Pain
Study Objective The project aims to implement an interdisciplinary therapeutic program for people suffering from persistent pain (specifically fibromyalgia) to optimize their quality of life through a comprehensive approach that…
- Trial name
- NCT07782255
- Testing
- Multimodal Interdisciplinary Therapeutic Intervention
- Where
- Chile
- Volunteers
- 15 people
- Sponsor
- Playa Ancha University
Persistent Idiopathic Facial Pain
Atypical Orofacial Pain Diagnostics and Differentiation.
Orofacial pain is diagnosed for more than 1.9 percent of general population and for 0.3 percent origin of the facial pain is unknown.
- Trial name
- NCT04775758
- Testing
- Self-evaluating questionnaires, iMotions analysis platform
- Where
- Lithuania
- Volunteers
- 150 people
- Sponsor
- Lithuanian University of Health Sciences
Orthopedic Disorder, Nontraumatic Injury
Web-based Mind-body Program to Improve Resilience Among Risky Substance Users With Persistent Upper Extremity Pain
The investigator aims to conduct a feasibility randomized controlled trial (RCT) (N=50) to test the feasibility, acceptability, and credibility of an asynchronous web-based mind-body intervention (Toolkit for Resilient Life…
- Conditions
- Orthopedic Disorder, Nontraumatic Injury, Upper Extremity Pain, Risky Substance Use
- Trial name
- NCT06991205
- Testing
- Web-TIRELESS, Web-MEUC
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Jafar Bakhshaie
Breast Cancer
Effectiveness of an eHealth Self-management Support Program for Persistent Pain After Breast Cancer Treatment
The scientific goals of the project are: 1. The primary scientific objective of the study is to determine the effectiveness of an eHealth self-management support program for persistent pain after breast cancer treatment compared…
- Trial name
- PECAN (NCT06308029)
- Testing
- eHealth self-management support program, Face-to-face rehabilitation program
- Where
- 2 sites in Belgium
- Volunteers
- 270 people
- Sponsor
- Universiteit Antwerpen
Pain, Persistent Pain
Is Low-load Resistance Training With Blood Flow Restriction More Effective Than Traditional Rehabilitation of Military Personnel With Lower Limb Injuries
Pain can be one of the primary limiting factors to progress following musculoskeletal injury and may be caused by trauma or degenerative changes.
- Conditions
- Pain, Persistent Pain, Musculoskeletal Pain
- Trial name
- LIMITLESS (NCT06621953)
- Testing
- BFR, control group
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- Defence Medical Rehabilitation Centre, UK
Recurrent Low Back Pain, Persistent Low Back Pain
Chiropractic Maintenance Care of Persistent or Recurrent Low Back Pain
As low back pain is often a recurrent and sometime persistent problem, research into prevention is important. Chiropractors have traditionally treated patients with maintenance care, which means that patients are seen on a…
- Conditions
- Recurrent Low Back Pain, Persistent Low Back Pain, Chronic Low Back Pain
- Trial name
- NCT01539863
- Testing
- maintenance care, Treatment as needed
- Where
- Sweden
- Volunteers
- 328 people
- Sponsor
- Karolinska Institutet
Neck Pain
Risk Factors and Risk Profiles for Persistent Neck Pain in Young Adults: Results From the HUNT Study
Neck pain is one of the most prevalent musculoskeletal disorder in Norway among older adolescents and young adults. Despite this, little research exist on risk factors for neck pain in the transitional life phase from adolescence…
- Trial name
- NCT04201366
- Testing
- No intervention
- Where
- Norway
- Volunteers
- 8,562 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Long COVID, Pain
Effects of an Active Coping Program in Patients With Persistent Post-Covid Pain.
Justification: among the sequelae of Covid-19 in clinical practice we frequently find persistent neuromusculoskeletal pain. Previous studies carried out by this research group and in the scientific literature have shown that…
- Trial name
- NCT05894629
- Testing
- Pain Neuroscience Education (PNE)+ Therapeutic Exercise (TE), Active Comparator: Usual treatment
- Where
- Spain
- Volunteers
- 89 people
- Sponsor
- University of Valladolid
Osteoarthitis
Evaluating the Role of Genicular Artery Embolization in Treatment of Persistent Pain in Patients With Severe Knee Osteoarthritis
The goal of this randomized clinical trial is to evaluate the role of genicular artery embolization (GAE) in treating persistent pain in patients with severe knee osteoarthritis who have failed conservative treatment and may be…
- Trial name
- NCT07763158
- Testing
- embolization therapy, Conservative treatment
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Abdullah International Medical Research Center
Post-Operative Pain Following Total Knee Arthroplasty
Pilot Study of PEMF Therapy in Treatment of Post-operative Pain Following Total Knee Arthroplasty
The purpose of this study is to investigate whether pulsed electromagnetic energy field (PEMF) therapy is effective in the treatment of persistent pain following total knee arthroplasty (TKA)
- Trial name
- NCT02211534
- Testing
- Pulsed Electromagnetic Field Device (Provant)
- Where
- 14 sites in United States
- Volunteers
- 35 people
- Sponsor
- Regenesis Biomedical, Inc.