Clinical trials: Persistent Pain
Pain, Chronic Post-Surgical
PERIoperative Holistic RIsk Factor SCreening in the Prevention of Persistent Pain
Assessment and management for improved wellbeing after elective surgery (PERISCOP³E-Care) Diagnostic assessment tool evaluation and cut-off determination for participation in a transmural perioperative care program
- Trial name
- PERISCOPEcare (NCT05526976)
- Testing
- PERISCOPE-care
- Where
- 2 sites in Belgium
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Breast Cancer, Survivorship
Dance Study for Post-surgical Pain in Breast Cancer Survivors
The purpose of this study is to examine how a 12-week, virtual dance program may improve pain and quality of life in participants with persistent post-surgical pain, or PPSP, following mastectomy or lumpectomy.
- Conditions
- Breast Cancer, Survivorship, Pain, Postoperative
- Trial name
- NCT06758102
- Testing
- Dance Program
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Lumbar Surgery
Study of PEMF (Pulsed Electromagnetic Field) Therapy in the Treatment of Persistent Post-Operative Pain Following Lumbar Surgery
To demonstrate the analgesic effectiveness of 2 modalities of PEMF treatment compared to sham treatment in patients with persistent pain following lumbar surgery when treatment is administered twice daily over a 60 day period.
- Trial name
- NCT02416973
- Testing
- Provant
- Where
- 8 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Regenesis Biomedical, Inc.
Neck Pain
Risk Factors and Risk Profiles for Persistent Neck Pain in Young Adults: Results From the HUNT Study
Neck pain is one of the most prevalent musculoskeletal disorder in Norway among older adolescents and young adults. Despite this, little research exist on risk factors for neck pain in the transitional life phase from adolescence…
- Trial name
- NCT04201366
- Testing
- No intervention
- Where
- Norway
- Volunteers
- 8,562 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Persistent Idiopathic Facial Pain (PIFP)
Deciphering Persistent Orofacial Pain - PIFP
Persistent non-dental orofacial pain is common yet poorly characterised, and its pathophysiology remains largely unknown. Two clinically similar entities are distinguished: post-traumatic trigeminal neuropathic pain (PTNP), in…
- Trial name
- NCT07791004
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Chronic Pain, Osteo Arthritis Knee
Persistent Pain in Pharmacologically or Surgical Treated Osteoarthritis: Role of Mu-Limpho Marker
The goal of this prospective observational study is to analyze the percentage of expression of B and NK cells expressing Mu opioid receptor on their surface, named Mu-Lympho-Marker (MLM), to measure pain progression in…
- Trial name
- MLM (NCT06637709)
- Where
- Italy
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele Roma
Low Back Pain
Characterizing the Role of Pain Sensitivity in Acute to Persistent Low Back Pain
This research study will examine whether enhanced pain sensitivity increases the risk of persistent low back pain. The study will address the highly prevalent and costly condition of persistent low back pain and a major obstacle…
- Trial name
- NCT01981382
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Fatigue, Pain
Molecular Determinants of Persistent Cancer Related Fatigue
The purpose of this study is to determine if inflammatory markers in blood as well as brain neurotransmitters (markers of in-brain activity and metabolism) are related to long-term or chronic fatigue.
- Conditions
- Fatigue, Pain, Poor Sleep Quality
- Trial name
- MDOF (NCT01980719)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Chronic Pain, Persistent Pain
Physiotherapy Intervention Program for Chronic Pain Associated With Depressive Disorder
This prospective longitudinal pre-post intervention study aims to evaluate the effects of an 8-week physiotherapy program combining face-to-face and asynchronous tele-rehabilitation sessions in individuals with chronic persistent…
- Conditions
- Chronic Pain, Persistent Pain, Depressive Disorder
- Trial name
- NCT07764848
- Testing
- Hybrid Physiotherapy Program
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Hydromorphone Use, Acute Postoperative Pain
Methadone and Hydromorphone For Spinal Surgery
Patients undergoing major spinal surgery continue to experience moderate-to-severe pain during the first 2-3 days following the operative procedure.
- Conditions
- Hydromorphone Use, Acute Postoperative Pain, Patient Satisfaction, Chronic Persistent Surgical Pain
- Trial name
- NCT02107339
- Testing
- Methadone, Hydromorphone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Pain, Experimental
Could Self-distancing Alter the Perception of Experimental Pain?
Physical pain leads to a narrow, egocentric focus on the self, in the here and now, particularly when experienced at high intensity levels.
- Trial name
- NCT05511857
- Testing
- Self-distancing, third-person self-talk., Self-immersed, first-person self-talk., Distraction
- Where
- Sweden
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- Linnaeus University
Pain, Chronic
Flippin Pain: A Public Health Campaign Evaluation
An online webinar aiming to improve the public beliefs related to persistent pain will be offered to members of the public in the UK via social media and targeted via written invitation to individuals on a waiting list for pain…
- Trial name
- NCT04903379
- Testing
- Education
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Teesside University
Pain
Ultrasound Guided Blocks of the Iliohypogastric and Ilioinguinal Nerves in Persistent Postherniorrhaphy Pain Patients
In this controlled study the investigators will examine the analgesic and sensory effects of ultrasound-guided blocks of the iliohypogastric and ilioinguinal nerves with lidocaine in persistent postherniorrhaphy pain patients.
- Trial name
- NCT01373593
- Testing
- lidocaine
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pain, Postoperative
Persistent Postoperative Pain Incidence With Gabapentin Used
The study's objective will be to evaluate the gabapentine efficiency in orally and long term used after painfully surgeries.
- Trial name
- PPP (NCT02693821)
- Testing
- Gabapentin
- Where
- Argentina
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Chronic Post Operative Pain
Prevalence and Risk Factors for Postsurgical Pain After the Open Reduction and Internal Fixation of Lower Limbs.
The objective of this study is to specify the demographic and medical factors that most likely constitute a risk of developing CPSP in the patients with lower limb.
- Trial name
- NCT06136663
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Xuzhou Central Hospital
Musculoskeletal Pain
"Social Acceptance Among Peers and Musculoskeletal Pain in Adolescents"
Musculoskeletal pain is common and often occurs already in adolescence. To be able to target future interventions that aim to prevent new episodes of MSK pain, more studies on modifiable risk factors are necessary.
- Trial name
- NCT04526522
- Testing
- No intervention
- Where
- Norway
- Volunteers
- 961 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Chronic Daily Headache, Chronic Migraine
Analysis of Headache Chronification With Imaging, Deep Phenotyping, and Proteomics
Study is aimed at determining why some patients with episodic headache proceed to chronic daily or near daily headaches. The Investigators seek to discover differences in brain anatomy and function, composition of cerebrospinal…
- Trial name
- NCT03231241
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Stanford University
Inflammatory Bowel Diseases, Chronic Pain
Somatosensory Profiles in Individuals With Persistent Musculoskeletal Pain and Inflammatory Bowel Disease
This study evaluates nervous system hypersensitivity in individuals with inflammatory bowel disease (IBD) and experiences of ongoing musculoskeletal (MSK) pain.
- Conditions
- Inflammatory Bowel Diseases, Chronic Pain, Central Sensitization
- Trial name
- NCT03799471
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Pain, Postoperative, Root Resorption
Evaluation of Different Medicaments in the Management of Necrotic Primary Molars by Lesion Sterilization and Tissue Repair
Management of non-vital primary molars is challenging due to the natural anatomy of primary teeth, patients' young age, and their behavior toward dental treatment.
- Conditions
- Pain, Postoperative, Root Resorption, Persistent Infection, Necrotic Pulp
- Trial name
- NCT06926322
- Testing
- Conventional double antibiotic paste of Metronidazole 500 mg plus Ciprofloxacin 500 mg mixed with propylene glycol, Double antibiotic paste of Metronidazole and Ciprofloxacin loaded chitosan-coated silver nanoparticles, chitosan-coated silver nanoparticles
- Where
- Egypt
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
New Daily Persistent Headache, New Daily Persistent Headache (NDPH)
New Daily Persistent Headache Biomarkers Study
New daily persistent headache is a debilitating syndrome which is seldom researched, poorly understood, and without effective treatments. Chronic migraine is a more common but similarly disabling disorder.
- Trial name
- NDPH (NCT04260087)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine