Clinical trials: Peritoneal Inflammation
Peritonitis
Point-of-care Test for Diagnosis of Peritonitis in Peritoneal Dialysis Patients
Peritoneal dialysis (PD) is a home-based dialysis therapy and peritonitis is a serious complication in PD. A reliable point-of-care test to detect peritonitis is important for patients to self-detect peritonitis at home as…
- Trial name
- Periplex (NCT04070196)
- Testing
- Periplex
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Singapore General Hospital
Peritonitis, Malnutrition
Probiotics Use in the Chronic Peritoneal Dialysis Patients
The purpose of this study is to determine whether probiotics can improve the nutrition status and prevent peritonitis in the chronic peritoneal dialysis patients.
- Trial name
- NCT01076426
- Testing
- Pro-biotics, Oligosaccharide
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Cheng-Kung University Hospital
Peritonitis, Kidney Failure
The Study of Infection and Cell Inflammation in Peritoneal Dialysate
A progressive decline of plasma triggering receptor expressed on myeloid cells-1 (TREM-1) concentration indicates a favorable clinical evolution during the recovery phase of sepsis.
- Trial name
- NCT00173485
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Ascites Infection
Rifaximin Prophylaxis for Spontaneous Bacterial Peritonitis and Hepatorenal Syndrome in Cirrhotic Patients
Norfloxacin is the most commonly used drug for the prophylaxis against spontaneous bacterial peritonitis (SBP) in patients with liver cirrhosis.
- Trial name
- NCT05621005
- Testing
- Rifaximin 550 milligram Oral Tablet [XIFAXAN]
- Where
- Egypt
- Volunteers
- 104 people
- Sponsor
- Samar Atef Sebaweh Mohammed
Incisional Hernia, Abdominal Hernia
Hernia Sac Flap Coverage of Mesh in Bony-Edged Ventral Hernia Repair
This trial asks whether covering the inner, bowel-facing surface of a hernia mesh with a flap of the patient's own hernia sac improves healing after repair of a complex ventral (abdominal wall) hernia in which one edge of the…
- Conditions
- Incisional Hernia, Abdominal Hernia, Complex Ventral Hernia, Surgical Site Infection
- Trial name
- PERI-SAC (NCT07720154)
- Testing
- Sac-flap peritonealization of the mesh, Retromuscular (sublay) synthetic mesh repair
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Minia University
Incisional Hernia
PROPHYlactic Implantation of BIOlogic Mesh in Peritonitis (PROPHYBIOM)
To evaluate the efficacy of the use of swine dermal collagen prosthesis implanted preperitoneally as a prophylactic procedure against incisional hernia in patients operated in urgency/emergency setting in contaminated/infected…
- Trial name
- PROPHYBIOM (NCT02277262)
- Testing
- Biological swine dermis not cross-linked prosthesis positioning in incisional hernia prevention, Direct suture of the anterior abdominal wall fascia
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Spontaneous Bacterial Peritonitis
Laboratory Diagnosis of Spontaneous Bacterial Peritonitis
This study aims at evaluating the diagnostic accuracy of serum procalcitonin, PEC index, modified Wehmeyer, and Mansoura scoring systems for SBP in cirrhotic patients with ascites
- Trial name
- SBP (NCT05696054)
- Volunteers
- 80 people
- Sponsor
- Sohag University
Perforated Diverticulitis
The Damage Control Strategy for the Treatment of Perforated Diverticulitis of the Sigmoid Colon With Diffuse Peritonitis
The best approach for the treatment of perforated diverticulitis of the sigmoid colon is still under debate. Concurrent techniques are 1) resection with primary colorectal anastomosis with or without additional loop ileostomy; 2)…
- Trial name
- NCT04220840
- Testing
- Damage control strategy
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- Städtisches Klinikum München GmbH
Spontaneous Bacterial Peritonitis, Cirrhosis
Randomized Comparison of Two Albumin Administration Schedules for Spontaneous Bacterial Peritonitis (SBP)
Spontaneous bacterial peritonitis (SBP) is a common and frequently fatal complication of end-stage liver disease with a mortality of up to 10%, primarily due to the development of kidney failure.
- Trial name
- NCT00761098
- Testing
- Standard Care, Experimental
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Weill Medical College of Cornell University
Therapeutic Procedural Complication
Outcome and Risk Factors For Mortality in Peritoneal Dialysis Patients: 20 Years Experience in a Single Turkish Center
INTRODUCTION AND AIMS: The aims of this study were to evaluate patient and technique survival rates, investigate peritonitis rates and evaluate factors affecting mortality in peritoneal dialysis (PD) patients over a period of 20…
- Trial name
- NCT02922270
- Testing
- Peritoneal dialysis patients at the Istanbul Medical Faculty
- Volunteers
- 277 people
- Sponsor
- Istanbul University
Cholecystitis, Acute, Cholecystitis; Gangrenous
Risk Factors for Necrotic Cholecystitis During COVID-19 Pandemic.
Gangrenous cholecystitis is the most common complication of acute cholecystitis. Preliminary data showed that COVID-19 patients have a high risk to present necrotic cholecystitis.
- Conditions
- Cholecystitis, Acute, Cholecystitis; Gangrenous, Cholecystitis Suppurative, Covid19
- Trial name
- ChoCO-W (NCT04542512)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Poissy-Saint Germain Hospital
Peritoneal Dialysis-associated Peritonitis
Defining the Optimal Duration of Treatment for "Low-Risk" Peritoneal Dialysis-Related Peritonitis
Background According to the International Society for Peritoneal Dialysis (ISPD) recommendations, "low-risk" peritoneal dialysis (PD)- related peritonitis caused by coagulase-negative staphylococcal species, Streptococcal…
- Trial name
- NCT03675854
- Testing
- Cefazolin
- Where
- Hong Kong
- Sponsor
- Chinese University of Hong Kong
Spontaneous Bacterial Peritonitis
Rifaximin for the Secondary Prevention of Spontaneous Bacterial Peritonitis Recurrence in Cirrhotic Patients
The aim of this study is to evaluate whether long-term rifaximin administration reduces spontaneous bacterial peritonitis recurrence rate in cirrhotic patients.
- Trial name
- NCT02011841
- Testing
- Rifaximin, Ciprofloxacin
- Where
- South Korea
- Sponsor
- Seoul National University Hospital
Abscess, Intra-Abdominal, Cholecystitis
Cefoperazone/Sulbactam In The Treatment Of Serious Intra-Abdominal And Hepatobiliary Infections.
The primary objective is to collect data on treatment outcomes (clinical and microbiological cure), safety and tolerability of treatment with cefoperazone/sulbactam in patients with serious intra-abdominal and hepatobiliary…
- Conditions
- Abscess, Intra-Abdominal, Cholecystitis, Wound Infections, Peritonitis
- Trial name
- NCT00463762
- Testing
- CP-75385-02 Cefoperazone/sulbactam
- Sponsor
- Pfizer
Abscess, Intra-Abdominal, Abdominal Abscess
A Safety and Tolerability Study of Doripenem Compared With Meropenem in Children Hospitalized With Complicated Intra-abdominal Infections
The purpose of the study is to evaluate the safety and tolerability of doripenem compared with meropenem in children hospitalized with complicated intra-abdominal infections.
- Conditions
- Abscess, Intra-Abdominal, Abdominal Abscess, Abdomen, Acute, Abdominal Pain
- Trial name
- NCT01110382
- Testing
- Doripenem, Meropenem, Amoxicillin/clavulanate potassium
- Where
- 19 sites in United States, Argentina and 6 more
- Volunteers
- 41 people
- Sponsor
- Janssen Research & Development, LLC
Peritonitis
A Pharmacokinetic Study of Cefepime After Administration Into Dialysate in Patients With Continuous Ambulatory Peritoneal Dialysis (CAPD) Peritonitis
Cefepime is a broad-spectrum antibiotic used in treating CAPD peritonitis. However, medical knowledge has been lacking with regard to its pharmacokinetic profile after it has been administered intraperitoneally.
- Trial name
- NCT00497744
- Testing
- Intraperitoneal Cefepime
- Where
- 2 sites in China
- Volunteers
- 6 people
- Sponsor
- Hospital Authority, Hong Kong
Peritonitis
Comparative Evaluation of Intra-operative Peritoneal Lavage With Super Oxidized Solution and Normal Saline in Peritonitis Cases
Super Oxidized Solution (SOS) was used in peritonitis and results were compared by using normal saline solution in two groups. Abdominal fluid was taken to check for bacterial load after giving lavage with SOS solution and in…
- Trial name
- NCT02882932
- Testing
- Super Oxidized Solution in group I
- Volunteers
- 290 people
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Acute Appendicitis, Acute Appendicitis Without Peritonitis
The Role of Preoperative HALP Score in Differentiating Complicated Acute Appendicitis
Acute abdomen is a frequently encountered clinical condition that can be fatal if not diagnosed early. Acute appendicitis is one of the causes of acute abdomen and is the most common clinical condition leading to acute abdomen…
- Conditions
- Acute Appendicitis, Acute Appendicitis Without Peritonitis, Acute Appendicitis With Appendix Abscess, Acute Appendicitis With Rupture
- Trial name
- Appendicitis (NCT07002671)
- Testing
- Appendectomy, blood sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 411 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Heart Failure
Effects of Atorvastatin Treatment on Left Ventricular Diastolic Function in Peritoneal Dialysis Patients
Background Heart failure is the final consequence of various heart disease and is also the leading cause of mortality worldwide.
- Trial name
- ALEVENT (NCT01503671)
- Testing
- Atorvastatin
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- National Taiwan University Hospital
Postoperative Pain
Effects of Perioperative Administration of Intravenous Lidocaine in Children Operated on for Acute Generalized Peritonitis
Intravenous administration of lidocaine perioperatively after laparotomy for peritonitis could be an interesting alternative by reducing the duration of postoperative ileus, the intensity of pain and the patient's hospital stay…
- Trial name
- NCT06051630
- Testing
- Lidocaine intravenous, Serum saline intravenous
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Université NAZI BONI