Clinical trials: Peripheral Vestibular Disorder
Vestibular Disorder, Vestibular Schwannoma
Measuring Vestibular Organ Function With Weak Alternating Current Stimulation
The goal of this clinical trial is to preliminarily evaluate the use of electrical stimulation in diagnosing disorders with the vestibular system.
- Conditions
- Vestibular Disorder, Vestibular Schwannoma, Vestibular Neuritis
- Trial name
- VESTI (NCT07267910)
- Testing
- Active transcranial electrical vestibular stimulation (Active EVS), Control measurement
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Aalto University
Vertigo, Peripheral
Non Inferiority of Meclin® (Meclizine Chlorhydrate) Versus Dramin® (Dimenhydrinate) in Control of Acute Vertigo Symptoms From Peripheral Origin
Evaluation of the non inferiority of Meclin (meclizine) versus Dramin (Dimenhydrinate) to treat the symptoms of acute vertigo from peripheral origin after up to 4 weeks of treatment; Evaluation of impact on quality of life in…
- Trial name
- NCT02112578
- Testing
- Meclizine, Dimenhydrinate
- Where
- 7 sites in Brazil
- Volunteers
- 292 people
- Sponsor
- Apsen Farmaceutica S.A.
Vestibular Schwannoma, Acoustic Neuroma
Study of Aspirin in Patients With Vestibular Schwannoma
This is a phase II prospective, randomized, double-blind, longitudinal study evaluating whether the administration of aspirin can delay or slow tumor growth and maintain or improve hearing in VS patients.
- Conditions
- Vestibular Schwannoma, Acoustic Neuroma, Neurofibromatosis 2
- Trial name
- NCT03079999
- Testing
- Aspirin
- Where
- 5 sites in United States
- Volunteers
- 97 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Peripheral Vestibular Disorder
Comparison of Optokinetic Stimulation Treatments
Persons with a vestibular (e.g. inner ear) disorder often report visual induced dizziness (ViD) symptom (i.e. postural and/or gait instability, dizziness, disorientation) provocation or exacerbation in environments with busy or…
- Trial name
- NCT04649268
- Testing
- Group B, Group A
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- King's College London
Vestibular Schwannoma, Vestibular Function Disorder
Role of Psychiatric Profile in Prehabituated Patients After Vestibular Schwannoma Surgery
The aim of this study is to assess effect of psychiatric profile on visual sensitivity and overall health status in patients who underwent surgery for vestibular schwannoma and were prehabituated by chemical vestibular ablation.
- Trial name
- NCT03638310
- Testing
- intratympanic application of gentamicin, microsurgical removal of vestibular schwannoma
- Where
- Czechia
- Volunteers
- 37 people
- Sponsor
- Charles University, Czech Republic
Vestibular Schwannoma
Vertigo Perception and Quality of Life in Patients After Surgical Treatment of Vestibular Schwannoma
Surgical removal of vestibular schwannoma causes acute vestibular symptoms, including postoperative vertigo and oscilopsia due to nystagmus. In general, the dominant symptom postoperatively is vertigo.
- Trial name
- ITG (NCT02963896)
- Testing
- gentamicin
- Volunteers
- 20 people
- Sponsor
- University Hospital, Motol
Nystagmus, Optokinetic Nystagmus
Effects of Gaze Stabilization Exercises and Optokinetic Training in Peripheral Vestibular Disorders
This study compares the effectiveness of Gaze Stabilization Exercises and Optokinetic Training in improving dizziness, balance, and confidence in individuals with peripheral vestibular disorders.
- Trial name
- NCT07583901
- Testing
- Gaze stabilization exercises, Optokinetic training
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Foundation University Islamabad
Dizziness Chronic, Vertigo, Peripheral
Virtual Environments for Vestibular Rehabilitation
The specific aims of this pilot project are: Aim #1: Determine the extent to which sensory integration strategies differ between 28 individuals with unilateral vestibular hypofunction and 28 age-matched peers.
- Conditions
- Dizziness Chronic, Vertigo, Peripheral, Fall
- Trial name
- NCT04268745
- Testing
- Balance training, Traditional Vestibular Rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- New York University
Neuroma, Acoustic
Clinical and Radiological Evaluation of Acoustic Neuromas With Spontaneous Shrinkage
To evaluate the regression characteristics of this Acoustic Neuroma population using volumetric data To study the relationship between regression and clinical characteristics including tinnitus, dizziness, hearing loss, and the…
- Trial name
- NCT03970681
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
Neurofibromatosis Type 2, Vestibular Schwannoma
Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)
This is a multi-arm phase II platform-basket screening study designed to test multiple experimental therapies simultaneously in patients with NF2-related schwannomatosis (NF2-SWN, formerly known as neurofibromatosis type 2) with…
- Conditions
- Neurofibromatosis Type 2, Vestibular Schwannoma, Non-vestibular Schwannoma, Meningioma
- Trial name
- INTUITT-NF2 (NCT04374305)
- Testing
- Brigatinib, Neratinib, Retifanlimab
- Where
- 6 sites in United States
- Volunteers
- 109 people
- Sponsor
- Scott R. Plotkin, MD, PhD
Vestibular Schwannoma
Novel Multimodality Imaging for Navigation in Skull Base Surgery
Successful neurosurgery to remove tumours around the base of the skull, such as a vestibular schwannoma, depends on achieving maximal tumour removal whilst preserving crucial neurological functions such as facial movement, and…
- Trial name
- SBN (NCT04128345)
- Testing
- Use of navigation system
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University College, London
Vestibular Schwannoma, Ototoxicity
Radiosurgery Induced Ototoxicity in Patients Treated for a Vestibular Schwannoma
The investigators aim to study the impact of stereotactic radiosurgery, for the treatment of vestibular Schwannoma, on the cochlear, vestibular, gustatory, and facial nerve functions and compare it with a conservatively treated…
- Trial name
- NCT05641441
- Testing
- Stereotactic radiosurgery
- Where
- Switzerland
- Volunteers
- 258 people
- Sponsor
- University Hospital, Geneva
Schwannoma, Vestibular, Neurofibromatosis 2
NF2 Natural History Consortium
OBJECTIVES: I. Define the growth rates and clinical course of NF2-related tumors in patients with neurofibromatosis type 2. Associate growth rate with physical function.
- Conditions
- Schwannoma, Vestibular, Neurofibromatosis 2, Meningioma
- Trial name
- NCT00004483
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- House Ear Institute