Clinical trials: Peripheral Vestibular Disorder
Acute Vestibular Syndrome, Emergencies
Eye-ECG Approach to Emergencies : Diagnostic Performance of the HINTS Test
Vertigo integrated with acute vestibular syndrome (AVS) is a frequent reason for emergency visits. The French and international literature estimates between 2 to 4% of vertigo prevalence among reasons for coming to emergencies.
- Trial name
- NCT04118361
- Testing
- HINTS Test, STANDING Algorithm
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Peripheral Vestibular Disorder, Benign Paroxysmal Positional Vertigo
Effect of Peripheral Vestibular Disease Location on Outcomes Following Home-based Virtual Reality Vestibular Therapy
This parallel-group randomized controlled trial aims to determine if the location of the lesion(s) in the vestibular system (unilateral versus bilateral, lateral semi-circular canal versus otolith) impacts the effectiveness of…
- Conditions
- Peripheral Vestibular Disorder, Benign Paroxysmal Positional Vertigo, Meniere Disease, Vestibular Neuritis
- Trial name
- VR-PVD-RCT (NCT05424302)
- Testing
- Standard Vestibular Rehabilitation with Adjunct At Home Virtual Reality Vestibular Rehabilitation, Standard Vestibular Rehabilitation with Adjunct Auditory Intervention
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Vestibular Schwannoma
Secondary Endolymphatic Hydrops and Vestibular Schwannomas on 3 Tesla MRI
Endolymphatic hydrops is well known of the lay public in its primary form that is Ménière disease. Nowadays, the best w ay to approach it in vivo, is to use magnetic resonance imaging (MRI).
- Trial name
- NCT03593577
- Where
- France
- Volunteers
- 185 people
- Sponsor
- University Hospital, Strasbourg, France
Vestibular Schwannoma
Vestibular Outcomes in Vestibular Schwannoma
Previous studies have shown that vertigo is the symptoms that mostly affect quality of life in patients with vestibular schwannoma.
- Trial name
- VOVS (NCT03346889)
- Where
- Norway
- Volunteers
- 155 people
- Sponsor
- Haukeland University Hospital
BPPV, Vertigo
Cohort Study of Clinical and Neuroimaging Characteristics for BPPV Patients in China
The main objective is to analyze the abnormality of physical condition, mental health and blood examination of the patients with benign paroxysmal positional vertigo (BPPV).
- Conditions
- BPPV, Vertigo, Vertigo, Peripheral
- Trial name
- NCT06228196
- Testing
- Simultaneous cortico-spinal magnetic resonance imaging, Serum
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Peripheral Vestibular Disorders, Dizziness
Game Based Vestibular Exercise for Home Rehabilitation
Study Description and Purpose: The vestibular sense organs of the inner ear consist of the semi-circular canals and otolith end organs.
- Trial name
- NCT02134444
- Testing
- Experimental group, Control group
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Inner Ear Disease, Equilibrium; Disorder, Labyrinth
Unilateral Peripheral Vestibular Dysfunction: Reeducation and Spatial Orientation.
Motor control includes postural control and voluntary movement. For an optimal motor control it is necessary that brain integrates vestibular, visual and somatosensorial inputs properly, in a nonlinear way.
- Conditions
- Inner Ear Disease, Equilibrium; Disorder, Labyrinth, Spatial Navigation
- Trial name
- NCT03171181
- Testing
- Vestibular reeducation
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Neoplasms, Nervous System Disease
Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II Patients
Background: Neurofibromatosis type II (NF2) is associated with tumors of the nerves, brain, and spinal cord. Most people with NF2 develop vestibular schwannomas, or tumors on the hearing and balance nerves.
- Conditions
- Neoplasms, Nervous System Disease, Vestibular Disease
- Trial name
- NCT01222728
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Vestibular Schwannoma, Hearing Loss
Intraoperative EABR for Decision Making
In this study patients undergoing simultaneous translabyrinthine vestibular schwannoma resection and cochlear implantation are included. The goal of the study is to correlate the eABR results with postoperative hearing results.
- Trial name
- NCT03745560
- Where
- Austria
- Volunteers
- 15 people
- Sponsor
- Christoph Arnoldner
Vestibular Disorder, Peripheral Vestibular Disorder
Cervical Exercise in Peripheral Vestibular Disorders
70 patients with peripheral vestibular disorders will be included in the study. Half of the subjects will receive vestibular rehabilitation exercises and the other half will receive additional cervical exercises.
- Trial name
- NCT05430282
- Testing
- Only vestibular rehabilitation, Cervical exercises in addition to vestibular rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ege University
Vertigo, Peripheral
The Effect of Pinhole Glasses on Vestibular Electrical Stimulation
Balance is the ability to control and maintain the body's center of gravity within the support area. One of the important causes of imbalance is right or left sided unilateral vestibular hypofunction.
- Trial name
- NCT05516017
- Testing
- Vestibular Electrical Stimulator and Pinhole Glasses, Vestibular Electrical Stimulator
- Volunteers
- 100 people
- Sponsor
- Istanbul University
Vestibulopathy, Acute Peripheral
Vestibulopathy With Vestibulo Ocular Reflex (VOR) Gain Deficit
The study is examine the eye movements characteristics of patients with VOR gain deficits (overt and covert saccades) before and after physical therapy intervention program and examine the most effective physical therapy…
- Trial name
- VOR (NCT03271775)
- Testing
- physical therapy program (group), physical therapy program (computerized exercises)
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- University of Haifa
Vestibular Schwannoma
Gentamicin Treatment Prior to Schwannoma Surgery - Residual Function
The purpose of the study is to determine whether vestibular and postural compensation following schwannoma surgery is improved by ablating remaining vestibular function prior to surgery, through gentamicin injections in the…
- Trial name
- NCT02379754
- Testing
- Gentamicins
- Where
- Sweden
- Sponsor
- Lund University
Vestibular Schwannoma
Super-Selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Vestibular Schwannoma
A recent study by Plotkin et al. showed that bevacizumab (Avastin) treatment was followed by clinically meaningful hearing improvement, tumor-volume reduction, or both in some, but not all, patients with Vestibular Schwannoma…
- Trial name
- NCT01083966
- Testing
- Bevacizumab (Avastin)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwell Health
Vestibular Schwannoma, Cochlear Implantation
Simultaneous Cochlear Implantation During Translabyrinthine Resection of Vestibular Schwannoma
This study will address the feasibility of simultaneous cochlear implantation during resection of a vestibular schwannoma.
- Trial name
- NCT03958006
- Testing
- Cochlear implant
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Henry Ford Health System
Vertigo, Peripheral, Vestibular Disease
The Effect of Proprioseptive Vestibular Rehabilitation in Patients With Peripheral Vestibular Hypofunction
The aim of this study was to investigate the effect of proprioceptive vestibular rehabilitation on balance, functional mobility, posture, sensory profile and quality of life in patients with vertigo due to peripheral vestibular…
- Trial name
- NCT04687371
- Testing
- Proprioceptive vestibular exercise, Standard vestibular rehabilitation exercises, Controlled
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Inonu University
Vestibular Diseases
Virtual Reality-based Dual-task Exercise in Vestibular Hypofunction Patients
The aim is to assess the effects of virtual reality-based intervention on vestibular functions in in patients with chronic peripheral unilateral vestibular hypofunction.
- Trial name
- VR-VH-ex (NCT03536533)
- Testing
- Exergame
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- University of Zurich
Vestibular Schwannoma, NF2
Concentration and Activity of Lapatinib in Vestibular Schwannomas
Tumors can grow on the auditory nerves and can cause hearing loss. A common type of tumor that does this is a vestibular schwannoma (VS), or acoustic neuroma. These tumors are not cancerous. Most often, people have only one VS.
- Conditions
- Vestibular Schwannoma, NF2, Neurofibromatosis 2, Acoustic Neuroma
- Trial name
- NCT00863122
- Testing
- lapatinib
- Where
- 7 sites in United States
- Volunteers
- 26 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Peripheral Vertigo.
Promethazine vs. Lorazepam for Treatment of Vertigo
This study was a prospective, randomized, double-blind, parallel group clinical trial designed to compare the efficacy of intravenous (IV) promethazine and lorazepam for the treatment of peripheral vertigo in Emergency Department…
- Trial name
- NCT01827293
- Testing
- Promethazine, Lorazepam
- Where
- Iran
- Volunteers
- 210 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Myasthenia Gravis, Guillain-Barre Syndrome
Neurology Inpatient Clinical Education Trial
The objective of this study is to compare the effectiveness of a personalized patient education program to the current hospital education and evaluate its impact using patient satisfaction scores.
- Conditions
- Myasthenia Gravis, Guillain-Barre Syndrome, Multiple Sclerosis, Seizures
- Trial name
- NCT03826056
- Testing
- Current standard discharge educational intervention, Personalized discharge educational intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Dartmouth-Hitchcock Medical Center