Clinical trials: Peripheral Nerve Injury Upper Limb
Peripheral Nerve Injury Upper Limb
BMAC Nerve Allograft Study
This study is a prospective, multi-center, proof of principle, phase I human safety study evaluating the sequential treatments of the Avance Nerve Graft, a commercially available decellularized processed peripheral nerve…
- Trial name
- NCT03964129
- Testing
- Avance Nerve Graft with Autologous BMAC
- Where
- 3 sites in United States
- Volunteers
- 15 people
- Sponsor
- Brooke Army Medical Center
Peripheral Nerve Injuries
Electrical Stimulation to Enhance Peripheral Nerve Regeneration
The primary goal of this study is to quantify the functional deficits caused by injuries to the brachial plexus and peripheral nerve in the arm.
- Trial name
- NCT02403661
- Testing
- Post surgical electrical stimulation
- Where
- Canada
- Volunteers
- 136 people
- Sponsor
- University of Alberta
Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS)
Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test
The goal of this clinical trial is to understand how people make decisions about imaging tests for common musculoskeletal problems (like arthritis, tendon problems, or nerve compression).
- Conditions
- Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS), Lateral Epicondylitis, Osteoarthritis
- Trial name
- NCT07158892
- Testing
- Diagnostic Advance Care Planning Discussion, Informational Statement Only
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Texas at Austin
Fracture at Wrist and/or Hand Level, Rupture of Tendon of Wrist and Hand
USG Brachial Plexus Block for Upper Extremity Surgery
Ultrasound-guided (USG) brachial plexus (BP) block efficacy at the Supraclavicular (SCL), Lateral- Infraclavicular (LIC) and Axillary (AX) level: Randomized, observer-blinded study of the single-penetration…
- Conditions
- Fracture at Wrist and/or Hand Level, Rupture of Tendon of Wrist and Hand, Injuries to the Wrist, Hand and Fingers (S60-S69), Ganglion Cysts
- Trial name
- NCT01993290
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Jens Borglum Neimann
Trapeziometacarpal Arthrosis, Carpal Tunnel Syndrome
A Randomized Trial Measuring the Effect of Decision Aids on Patients' Satisfaction, Conflict of Decision-making and Clinical Outcome
The investigators plan a prospective randomized controlled study that compares the treatment decisions made by patients who receive decision aids, as compared to patients treated with usual care and the American Society for…
- Conditions
- Trapeziometacarpal Arthrosis, Carpal Tunnel Syndrome, Cubital Tunnel Syndrome, Distal Radius Fractures
- Trial name
- NCT01693094
- Testing
- Decision Aid
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Massachusetts General Hospital
Carpal Tunnel Syndrome
Urdu Version of Maastricht Upper Extremity Questionnaire Reliability Validity Study.
In this study, the examiners will investigate the reliability and validity of Mastrict Upper Extremity scale in Urdu language in Pakistani patients with Carpal tunnel syndrome.
- Trial name
- NCT06191003
- Where
- Pakistan
- Volunteers
- 135 people
- Sponsor
- Riphah International University
Spinal Cord Injury Cervical, Spinal Cord Injuries (Complete and Incomplete)
Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia
The goal of this clinical trial is to learn more about how stimulating the nerves involved in sensation (either in the limbs or in the brain) can be used to restore sensation in participants who have a spinal cord injury.
- Trial name
- NCT07225582
- Testing
- Brain Computer Interface (BCI) - Functional Electrical Stimulation (FES) system
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Case Western Reserve University
Carpal Tunnel Syndrome
Ultrasound-Guided Curved Needle Thread Carpal Tunnel Release: Efficacy and Safety of a Single-Center, Single-Arm Clinical Trial
Carpal tunnel syndrome is a set of symptoms and signs caused by compression of the median nerve within the carpal tunnel. The prevalence in the general population is about 3.72%, with a rising trend, making it the most common…
- Trial name
- NCT06440070
- Testing
- Loop Carpal Tunnel Release
- Where
- China
- Volunteers
- 69 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Tennis Elbow Syndrome, Golfer's Elbow
Effects of Peripheral Repetitive Peripheral Magnetic Stimulation on Individuals With Elbow or Wrist Chronic Pain
This pilot, randomized, sham-controlled, single-blind study will evaluate the effectiveness of repetitive peripheral magnetic stimulation (rPMS) in reducing pain in adults with tennis/golfer's elbow or carpal tunnel syndrome.
- Conditions
- Tennis Elbow Syndrome, Golfer's Elbow, Carpal Tunnel Syndrome (CTS)
- Trial name
- rPMS (NCT07544914)
- Testing
- Two days Active rPMS
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Anesthesia, Local, Hand Surgery
Postoperative Experience of 2 WALANT-type Modes of Anesthesia Used in Ambulatory Surgery of the Upper Limb.
Distal surgery of the upper limb under local anesthesia using the WALANT technique (Wide Awake Local Anesthesia No Tourniquet) has become the standard care in orthopedic surgery.
- Conditions
- Anesthesia, Local, Hand Surgery, Wrist Surgery, Elbow Surgery
- Trial name
- ROPIWA (NCT05343299)
- Testing
- Ambulatory surgery under Lidocaine alone, Ambulatory surgery under a combination of Lidocaine and Ropivacaine
- Where
- France
- Volunteers
- 91 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Acute Upper Extremity Trauma
Registry of Avive® Soft Tissue Membrane Utilization in Selected Applications of Acute Trauma of the Upper Extremity
A registry study to evaluate the role of Avive® Soft Tissue Membrane in the management of nerve injury associated with acute trauma in the upper extremity.
- Trial name
- ASSIST (NCT03943134)
- Testing
- Minimally Processed Human Umbilical Cord Membrane, Standard Surgical Procedures
- Where
- 3 sites in United States
- Volunteers
- 7 people
- Sponsor
- Axogen Corporation
Peripheral Nerve Injury, Peripheral Nerve Discontinuity
Study Comparing Avance Nerve Graft and Autograft for Functional Recovery Following Mixed and Motor Peripheral Nerve Reconstruction
This is a multicenter, 1:1 randomized, prospective, comparative study in participants requiring reconstruction of a mixed or motor nerve in the upper extremity.
- Conditions
- Peripheral Nerve Injury, Peripheral Nerve Discontinuity, Mixed Peripheral Nerve Injury, Motor Peripheral Nerve Injury
- Trial name
- Nerve-RESTORE℠ (NCT07657182)
- Testing
- Avance Nerve Graft, Sural nerve autograft
- Where
- 3 sites in United States
- Volunteers
- 178 people
- Sponsor
- Axogen Corporation
Complex Regional Pain Syndrome, Carpal Tunnel Syndrome
Examination of the Pathophysiologic Mechanisms of CRPS by Using QST, CPM, RIC, and Heart Rate Variability QST
This study aims for a better understanding of the pathophysiological mechanisms of the complex regional pain syndrome (CRPS). This will be done by testing the quantitative sensory testing, the remote ischemic conditioning, the…
- Conditions
- Complex Regional Pain Syndrome, Carpal Tunnel Syndrome, Neuralgia
- Trial name
- NCT02261012
- Where
- Germany
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Neuralgia, Postherpetic
Safety and Effectiveness of Repeated Administration of QUTENZA Patches for Treatment of Pain Caused by Nerve Damage
In this study all patients will be treated with the same medicine, the QUTENZA patch. Subjects will receive up to 6 QUTENZA patch applications over 12 months.
- Trial name
- STRIDE (NCT01252160)
- Testing
- QUTENZA
- Where
- 64 sites in Austria, Belgium and 14 more
- Volunteers
- 306 people
- Sponsor
- Astellas Pharma Inc
Peripheral Nerve Injury Upper Limb
Reconstruction of Digital Nerve Lesions With Muscle-in-Vein Conduits
Muscle-in-vein conduits (MVCs) provide an alternative for bridging digital nerve defects when tension-free suture is not possible.
- Trial name
- NCT04788030
- Testing
- Nerve reconstruction
- Volunteers
- 37 people
- Sponsor
- BG Trauma Center Tuebingen
Chronic Pain, Low Back Pain
Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain
The purpose of this study is to investigate, in two phases: (1) the feasibility and safety of Virtual Embodiment Therapy in treating chronic pain of lower back and upper limbs and (2) the efficacy of Virtual Embodiment Therapy on…
- Conditions
- Chronic Pain, Low Back Pain, Fibromyalgia, Upper Extremity Dysfunction
- Trial name
- NCT04060875
- Testing
- Karuna Labs Virtual Reality Software
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Karuna Labs Inc.
Carpal Tunnel Syndrome (CTS), Wounds and Injuries, Hands
Evaluation of AI-Mouse Use in Patients With Hand and Wrist Conditions
People with hand and wrist conditions, such as carpal tunnel syndrome or hand injuries, often experience pain and discomfort when using a computer mouse.
- Conditions
- Carpal Tunnel Syndrome (CTS), Wounds and Injuries, Hands, Wounds and Injuries, Wrists, Hand Injuries
- Trial name
- NCT07707089
- Testing
- AI-Assisted Computer Input System, Conventional Computer Mouse
- Volunteers
- 15 people
- Sponsor
- Nazarbayev University
Quadriplegia, Spinal Cord Diseases
Nerve Transfers to Restore Hand Function in Spinal Cord Injury
This study seeks to evaluate the efficacy of nerve transfers in restoring hand function in patients with cervical spinal injuries.
- Conditions
- Quadriplegia, Spinal Cord Diseases, Spinal Cord Injuries
- Trial name
- NCT02861612
- Testing
- Nerve Transfer Surgery
- Where
- 2 sites in United States, Canada
- Sponsor
- Ottawa Hospital Research Institute
Ankle Fractures, Distal Radius Fracture
Nerve Block for Pain Control After Fracture Surgery
Surgical treatment for patients with a fracture of the ankle or distal radius is commonly offered on an outpatient basis. Patients are routinely discharged from hospital within 4 hours of their procedure.
- Trial name
- NCT05391464
- Testing
- Peripheral Nerve Block
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- MaineGeneral Health
Quadriplegia, Spinal Cord Diseases
Upper Extremity Surgery in Spinal Cord Injury
The goal of the investigators work is to establish how nerve transfers can be best used to improve upper extremity function in patients with cervical level spinal cord injury (SCI).
- Conditions
- Quadriplegia, Spinal Cord Diseases, Spinal Cord Injuries
- Trial name
- NCT01899664
- Testing
- Nerve Transfer Surgery
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Washington University School of Medicine