Clinical trials: Peripheral Nerve Blocks
Chronic Pain, Trigeminal Neuralgia
Regional-anaesthesiological Infiltration Techniques for the Management of Chronic Pain: a Retrospective Study
There is a significant debate whether local infiltration techniques may be a method to treat complicated chronic pain syndromes, e.g. refractory headache.
- Conditions
- Chronic Pain, Trigeminal Neuralgia, Cluster Headache, Post-Zoster Neuralgia
- Trial name
- RetroBlock (NCT03066037)
- Testing
- regional-anaesthesiological infiltration
- Where
- Germany
- Volunteers
- 83 people
- Sponsor
- Charite University, Berlin, Germany
Anesthesia, Total Knee Arthroplasty
The Efficacy of Peripheral Nerve Blocks With Intrathecal Morphine in Improving Analgesia After Unilateral Total Knee Arthroplasty
The purpose of this study is to determine whether intrathecal morphine (ITM) alone or its combination with peripheral nerve blocks (PNB) provides better analgesia for patients undergoing total knee arthroplasty (TKA).
- Trial name
- NCT02135120
- Testing
- Combined spinal epidural anesthesia technique with intrathecal morphine, A combination of combined spinal-epidural (with intrathecal morphine) and femoral nerve block, A combination of combined spinal-epidural (with intrathecal morphine) and femoral nerve block as well as sciatic nerve block
- Where
- Lebanon
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Sacral Erector Spinae Plane Block
Ultrasound Guided Sacral Erector Spinae Plane Block in vNOTES Surgery
Vaginal natural opening transendoscopic surgery (vNOTES) has emerged as a minimally invasive surgical approach in gynecological procedures.
- Trial name
- NCT07732322
- Testing
- Sacral ESP block
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Seyyid Furkan Kına
Pain, Fracture
Single Shot Versus OnQ Pump in Extremity Fractures
Peripheral nerve blocks have been well studied in the literature with generally good results for controlling post operative pain following orthopaedic surgery. Regional anesthesia has many benefits.
- Trial name
- NCT02280291
- Testing
- Ankle SSB, Ankle OnQ, DR SSB
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Nerve Block, Efficiency
Ultrasound-guided Femoral Nerve Block Without Electrical Stimulation of Peripheral Nerves
There is little work comparing the effectiveness of a femoral nerve block performed only under US guidance or US plus electrical stimulation of the peripheral nerve (EPN).
- Conditions
- Nerve Block, Efficiency, Femoral Nerve, Ultrasonography
- Trial name
- USvsUSEPN (NCT05209490)
- Testing
- Femoral nerve blockade under ultrasound control with a peripheral nerve stimulator, femoral nerve blockade under ultrasound control without a peripheral nerve stimulator
- Where
- Belarus
- Volunteers
- 40 people
- Sponsor
- Mogilev Regional Clinical Hospital
Hip Fractures
PENG vs Femoral Block for Hip Fracture Analgesia
This study aims to compare the Pericapsular Nerve Group (PENG) block with femoral block for hip fracture pain. Participants presenting to the hospital with a diagnosis of hip fracture and consenting to analgesic block will…
- Trial name
- NCT07073209
- Testing
- PENG Block Administration, Femoral Block Administration, Bupivacaine , epinephrine Dexamethasone
- Where
- United States
- Volunteers
- 352 people
- Sponsor
- Weill Medical College of Cornell University
Pain Management, Simulation
Simulation-Based Training for Ultrasound-Guided Perineural Catheter Insertion
This study will determine the efficacy of a teaching program incorporating hybrid simulation in training practicing anesthesiologists on ultrasound (US)-guided continuous peripheral nerve block (CPNB).
- Conditions
- Pain Management, Simulation, Training, Ultrasonography
- Trial name
- NCT01688271
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Regional Anesthesia Morbidity, Complication Following Peripheral Nerve Block
Comparison of the Effects of Interscalene Block and Superior Trunk Block on Pulmonary Functions
The interscalene block (ISB) is one of the peripheral nerve blocks providing surgical anesthesia and postoperative analgesia in shoulder arthroscopy, eliminating the need for general anesthesia.
- Conditions
- Regional Anesthesia Morbidity, Complication Following Peripheral Nerve Block, Phrenic Nerve Paralysis
- Trial name
- NCT06703281
- Testing
- Interscalene Nerve Block, Superior trunk block
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Gazi University
Central Post Stroke Pain
Peripheral Sensory Input in Central Post Stroke Pain (CPSP)
Prospective, open-label study in 10 patients with Central Post Stroke Pain (CPSP). The study will evaluate the effects of peripheral nerve blockade on spontaneous pain and evoked thermal and mechanical responses in CPSP, and…
- Trial name
- NCT02148588
- Testing
- Ultrasound-guided peripheral nerve block with 2% lidocaine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Washington University School of Medicine
Moderate-to-severely Painful Ankle Surgery
Liposomal Bupivacaine Versus Continuous Peripheral Nerve Blocks for Analgesia Following Ankle Surgery
Postoperative pain remains undertreated. Opioids have well-known limitations for both individuals and society, and while single-injection peripheral nerve blocks with unencapsulated local anesthetic provide potent analgesia…
- Trial name
- NCT06995352
- Testing
- Popliteal nerve block including liposomal bupivacaine, Adductor canal nerve block including liposomal bupivacaine, Continuous popliteal nerve block with normal saline
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of California, San Diego
Bladder Cancer, Nerve Sheath Tumor
Imaging Study of [89Zr]DFO-YS5 for Cancer Detection
This is a single-center, pilot, PET-imaging study of the novel radiotracer 89Zirconium-89 DFO conjugated to the YS5 monoclonal antibody ([89Zr]DFO-YS5) in participants with nerve sheath tumor, bladder cancer, or advanced solid…
- Conditions
- Bladder Cancer, Nerve Sheath Tumor, Nerve Sheath Tumors, Solid Tumor Malignancies
- Trial name
- NCT07664397
- Testing
- [89Zr]DFO-YS5, Positron Emission Tomography (PET)-Computerized tomography (CT)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Robert Flavell, MD, PhD
Acinar Cell Carcinoma, Adenoid Cystic Carcinoma
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors
This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may…
- Conditions
- Acinar Cell Carcinoma, Adenoid Cystic Carcinoma, Adrenal Cortical Carcinoma, Adrenal Gland Pheochromocytoma
- Trial name
- NCT02834013
- Testing
- Biospecimen Collection, Computed Tomography, Echocardiography Test
- Where
- 1,007 sites in United States, Guam
- Volunteers
- 798 people
- Sponsor
- National Cancer Institute (NCI)