Clinical trials: Peripheral Edema
Heart Failure, Cardiomyopathies
Multimodal Physiologic State Intelligence Study
The OMNIPHYS study will investigate whether multimodal ultrasound and other routinely collected clinical and physiologic data can be combined with artificial intelligence to characterize changes in a person's physiologic state…
- Conditions
- Heart Failure, Cardiomyopathies, Pulmonary Hypertension, Myocarditis; Acute or Subacute
- Trial name
- OMNIPHYS (NCT07814118)
- Testing
- OMNIPHYS Multimodal Ultrasound Imaging System
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Hypertension
Manidipine Versus Amlodipine in Patients With Hypertension
The purpose of this study is to evaluate the effect of a third-generation Calcium Channel Blocker (CCB), manidipine, compared with second-generation Calcium Channel Blocker (CCB), amlodipine, on the development of peripheral…
- Trial name
- NCT03106597
- Testing
- Manidipine 20mg, Amlodipine 10mg
- Where
- 3 sites in South Korea
- Volunteers
- 46 people
- Sponsor
- Korea University Guro Hospital
Diabetic Macular Edema
Ranibizumab and Peripheral Scatter Laser in Patients With Diabetic Macular Edema and Peripheral Nonperfusion
To investigate the role of ranibizumab and angiographically-directed peripheral scatter laser therapy in patients with clinically-significant diabetic macular edema (CSME) and peripheral nonperfusion.
- Trial name
- RaScaL (NCT00815360)
- Testing
- intravitreal injection of ranibizumab, peripheral laser, intravitreal injection of triamcinolone acetonide
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Retina Associates of Florida, P.A.
Upper Limb Edema, Critical Illness
Near-Infrared Light Devices Versus Landmark Approach for Peripheral Venous Access in Intensive Care Unit
The central venous catheter (CVC) is commonly used in intensive care unit (ICU). The primary complications associated with CVCs especially with prolonged use include thrombosis and infections.
- Trial name
- NCT06234293
- Testing
- near-infrared light device
- Where
- 4 sites in France
- Volunteers
- 380 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Cancer Pain, Intractable Pain
MRI Evaluation of Spinal Cord Edema After CT-Guided Percutaneous Cordotomy in Cancer Pain Patients
This observational study aims to evaluate changes in the spinal cord following CT-guided percutaneous cervical cordotomy performed for the treatment of intractable cancer-related pain.
- Conditions
- Cancer Pain, Intractable Pain, Spinal Cord Edema, Neuropathic Pain
- Trial name
- CORD-MRI (NCT07400055)
- Testing
- CT-guided Percutaneous Cervical Cordotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Mersin University
Heart Failure, Chronic Heart Failure
The HEARTFELT Study
This pragmatic randomized crossover trial looks at the effect(s) of using a remote patient monitoring device (Heartfelt device) with health alerts to monitor the development of peripheral edema in patients with heart failure…
- Trial name
- HEARTFELT (NCT06222099)
- Testing
- Heartfelt Device installed, Standard care, Heartfelt-guided care
- Where
- 3 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- Heartfelt Technologies
Post-traumatic Carpal Tunnel Syndrome, Complex Regional Pain Syndrome
Use of Compression Glove to Prevent Complications After Distal Radius Fractures: a Randomized Controlled Trial
Distal radius fractures (DRF) are the most common type of fracture in the human body, and a large proportion of DRFs result in complications.
- Conditions
- Post-traumatic Carpal Tunnel Syndrome, Complex Regional Pain Syndrome, Edema
- Trial name
- NCT01118715
- Testing
- Compression glove
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- J&M Shuler
Leukemia
Ultrafiltration (Aquapheresis) in Patients With Leukemia and Severe Fluid Overload
The goal of this clinical research study is to learn about the safety and level of effectiveness of aquapheresis compared to diuretic drugs. Diuretic drugs are designed to help the kidneys to form more urine.
- Trial name
- NCT01508260
- Testing
- Aquapheresis, Furosemide
- Sponsor
- M.D. Anderson Cancer Center
Complex Regional Pain Syndrome Type I
Effect of Kinesiotaping on Pain,Edema and Kinesiophobia in Patients With Complex Regional Pain Syndrome
Patients will be divided into 2 groups according to the random numbers table, and both groups will receive a conventional physical therapy and rehabilitation program and nutritional support.
- Trial name
- NCT06302920
- Testing
- Kinesiotape
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Alanya Alaaddin Keykubat University
Heart Failure, Diastolic, Edema Brain
Feasibility Study of a New Peripheral Oedema Monitor for Heart Failure
The study aims at assessing the usefulness of the Heartfelt1 device in patients suffering from heart failure, who have peripheral oedema. The device is non-contact and does not requires patient compliance to work.
- Conditions
- Heart Failure, Diastolic, Edema Brain, Decompensated Heartfailure
- Trial name
- NCT02993601
- Testing
- Heartfelt-1, Weighing scales, Medical grading of oedema
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Heartfelt Technologies
Hypertension, Hypotension
Trial Assessing the Effect of Preoperative Furosemide on Intraoperative Blood Pressure
The purpose of this study is to determine whether continuing or discontinuing furosemide (a diuretic) on the day of elective noncardiac surgery for those who take furosemide on a chronic basis, causes more intraoperative…
- Conditions
- Hypertension, Hypotension, Edema, Congestive Heart Failure
- Trial name
- NCT00115726
- Testing
- furosemide
- Where
- 3 sites in United States, Canada
- Volunteers
- 198 people
- Sponsor
- University of Calgary
Diabetes Mellitus
Association Study of Genetic Polymorphisms of Candidate Genes With Thiazolidinedione-Related Peripheral Edema and Drug Responsiveness
According to the above evidence, though the exact mechanism contributing to the Thiazolidinediones (TZDs) associated peripheral edema is still unclear, the investigators hypothesize that the genetic variations of certain…
- Trial name
- NCT00975169
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- National Taiwan University Hospital
Macular Edema Caused by Leber's Miliary Aneurysms
Treatment of Macular Edema Caused by Leber's Miliary Aneurysms Using Intravitreal Aflibercept and Peripheral Laser Photocoagulation
This study evaluates the effectiveness of intravitreal Aflibercept (IVA) injection therapy, combined with peripheral laser photocoagulation, in the treatment of macular edema caused by Leber's miliary aneurysm.
- Trial name
- NCT03908723
- Testing
- Panretinal photocoagulation
- Where
- Egypt
- Volunteers
- 6 people
- Sponsor
- Alexandria University
Central Retinal Vein Occlusion With Macular Edema
Combination of Ranibizumab and Targeted Laser Photocoagulation
Intravitreal injections of Ranibizumab will be applied in all patients according to treatment guidelines. The experimental group will receive additional targeted laser photocoagulation of the peripheral areas of capillary…
- Trial name
- CoRaLaII (NCT04444492)
- Testing
- Ranibizumab Injection, Laser photocoagulation
- Where
- 12 sites in Austria, Germany
- Volunteers
- 88 people
- Sponsor
- University of Giessen
Idiopathic Edema
Efficacy and Safety Evaluation of Changes in Lower Extremity Edema of Radiofrequency
The purpose of this study is to verify the efficacy and safety of the radiofrequency stimulation compared to the sham stimulation in reducing lower extremity edema in adult women with idiopathic edema.
- Trial name
- NCT05185193
- Testing
- radiofrequency
- Where
- South Korea
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Osteoarthritis
Safety of Lumiracoxib in Patients With Osteoarthritis
This safety study evaluated the incidence of gastrointestinal adverse events and edema in patients with osteoarthritis treated with lumiracoxib and rofecoxib as comparator
- Trial name
- NCT00637949
- Testing
- lumiracoxib, rofecoxib
- Volunteers
- 309 people
- Sponsor
- Novartis
Parkinson's Disease, Peripheral Edema
Domperidone as a Treatment for Dopamine Agonist-induced Peripheral Edema in Patients With Parkinson's Disease
The dopamine agonists, pramipexole (Mirapex) and ropinirole (Requip), are drugs that are used to treat symptoms of Parkinson's disease.
- Trial name
- NCT00305331
- Testing
- Domperidone (drug)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University Health Network, Toronto
Peripheral Vestibular Disorder, Benign Paroxysmal Positional Vertigo
Effect of Peripheral Vestibular Disease Location on Outcomes Following Home-based Virtual Reality Vestibular Therapy
This parallel-group randomized controlled trial aims to determine if the location of the lesion(s) in the vestibular system (unilateral versus bilateral, lateral semi-circular canal versus otolith) impacts the effectiveness of…
- Conditions
- Peripheral Vestibular Disorder, Benign Paroxysmal Positional Vertigo, Meniere Disease, Vestibular Neuritis
- Trial name
- VR-PVD-RCT (NCT05424302)
- Testing
- Standard Vestibular Rehabilitation with Adjunct At Home Virtual Reality Vestibular Rehabilitation, Standard Vestibular Rehabilitation with Adjunct Auditory Intervention
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Healthy, Intravenous Catheterization
Effect of Flexible Catheter Materials on Catheter Angle and Blood Vessel Irritation
Peripheral intravenous catheters (PIVCs; commonly known as "cannulas") are very small tubes made out of rubber-like materials which are inserted into patients' arms using a needle to allow easy access to veins.
- Conditions
- Healthy, Intravenous Catheterization, Oedema, Thrombosis
- Trial name
- FLEXIT (NCT06927141)
- Testing
- Bilateral Peripheral Intravenous Catheterisation
- Where
- Australia
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Griffith University
Venous Insufficiency of Leg, Venous Reflux
Efficacy of Vasculera in Prevention on Post-op Pain and Edema Following Lower Extremity Venous Treatment in the Outpatient Setting
The purpose of this study is to evaluate the effectiveness of Vasculera in reducing post procedural pain, bruising and edema in the post procedure period for patients diagnosed with C2-C5 disease requiring an intervention(s).
- Conditions
- Venous Insufficiency of Leg, Venous Reflux, Varicose Veins, Lower Extremity Edema Chronic
- Trial name
- NCT02936271
- Testing
- Vasculera
- Where
- United States
- Sponsor
- Corewell Health West