Clinical trials: Peripheral Arterial Vascular Occlusion
Peripheral Arterial Disease
A Real-world Study to Evaluate the Effectiveness of Intravascular Lithotripsy in Moderate to Severe Calcification Lesion of Lower Extremity Femoropopliteal Artery
Vascular calcification is prevalent in patients with Peripheral artery disease (PAD), especially those with combined diabetes or chronic kidney disease.
- Trial name
- STRIKE (NCT06636968)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Zhongshan Hospital
Healthy, Diabetes Type 2
Assessment of Three Instruments for the Non-invasive Measurement of Arterial Stiffness.
The ASI Non-Invasive Arterial Stiffness Screening Device (ASI Device) is an investigational device under development for the non-invasive assessment of arterial stiffness.
- Conditions
- Healthy, Diabetes Type 2, Obesity, Coronary Artery Disease
- Trial name
- ASI-2012 (NCT01722474)
- Testing
- ASI Device
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Atherosclerotic Cardiovascular Disease, Coronary Artery Disease
Coated or Chewable Aspirin and a Hybrid Strategy to Mitigate Adverse Effects of Air Pollution in Stable Atherosclerotic Disease
Although both enteric-coated and plain formulations of aspirin are being used commonly, there are no high-quality comparisons between these formulations with respect to clinical efficacy outcomes in patients with atherosclerotic…
- Conditions
- Atherosclerotic Cardiovascular Disease, Coronary Artery Disease, Ischemic Heart Disease, Ischemic Stroke
- Trial name
- COATED-AIR (NCT06541691)
- Testing
- Enteric-coated aspirin, Plain aspirin, Hybrid strategy
- Where
- Iran
- Volunteers
- 3,000 people
- Sponsor
- Rajaie Cardiovascular Medical and Research Center
Peripheral Arterial Disease
Clinical Evaluation of the BlueDop Vascular Expert for Assessing Peripheral Arterial Disease
This is a BlueDop Vascular Expert System (BVE) Post-Market Clinical Follow-Up (PMCF) study. The primary objective of the study is to assess the clinical applicability and diagnostic accuracy of the BVE device in subjects who…
- Trial name
- NCT05073510
- Testing
- BVE
- Where
- 4 sites in Spain
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- BlueDop Medical LTD
Peripheral Arterial Disease
Ramipril Treatment of Claudication: Oxidative Damage and Muscle Fibrosis
Peripheral artery disease (PAD) is a manifestation of atherosclerosis that produces progressive narrowing and occlusion of the arteries supplying the lower extremities.
- Trial name
- NCT02842424
- Testing
- Ramipril
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Nebraska
Atherosclerosis, Lower Extremity Ischemia
Comparison of Prosthetic Femoropopliteal Bypass Versus Viabahn Endoprosthesis for Treatment of Symptomatic Femoral Artery Occlusive Disease
This study is a comparison of two different ways to treat blockage in the artery of the thigh. The first is an older way with incisions in the groin and just above the knee.
- Conditions
- Atherosclerosis, Lower Extremity Ischemia, Claudication, Rest Pain
- Trial name
- NCT00693823
- Testing
- Femoral-popliteal Bypass, Angioplasty and stent placement with Viabahn covered stent-graft(W.L. Gore & Associates, Flagstff, Arizona) of superficial femoral artery
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Texas Vascular Associates
Peripheral Artery Disease, Claudication, Intermittent
Lactate Increase in Peripheral Artery Disease
To our knowledge, the measurement of the transcutaneous oxygen pressure during walking is the only continuous method that estimates the importance of ischemia, bilaterally and segment of limb by segment of limb.
- Trial name
- STELLA (NCT03266861)
- Testing
- Exercise oximetry
- Where
- France
- Volunteers
- 750 people
- Sponsor
- University Hospital, Angers
Peripheral Arterial Disease, Arteriosclerosis
ARTPERfit Clinical Trial.
Peripheral arterial disease is part of the diseases derived from arteriosclerosis are the leading cause of mortality in developed countries.
- Trial name
- ARTPERfit (NCT04578990)
- Testing
- Walking intervention, Strength intervention, Concurrent intervention
- Where
- Spain
- Volunteers
- 124 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Peripheral Artery Disease, Critical Limb Ischemia
Comparison of Prevena Negative Pressure Incision Management System vs. Standard Dressing After Vascular Surgery
The purpose of this study is to evaluate the effectiveness of negative pressure incision management system (Prevena™ Incision Management System (PIMS) or ActiVAC® with the Prevena™ Dressings (Peel and Place™ or Customizable™)…
- Conditions
- Peripheral Artery Disease, Critical Limb Ischemia, Claudication
- Trial name
- NCT02389023
- Testing
- standard gauze dressing, Prevena Incision Management system
- Where
- 5 sites in United States
- Volunteers
- 242 people
- Sponsor
- University of Vermont Medical Center
Peripheral Artery Disease
Predicting Outcomes of PAD Patients Undergoing Endovascular Intervention With CTA
Lower extremity peripheral artery disease (PAD), the third leading cause of atherosclerotic cardiovascular morbidity following coronary artery disease and stroke, affect 200 million people worldwide and is associated with high…
- Trial name
- NCT03974880
- Where
- China
- Volunteers
- 480 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Peripheral Arterial Disease
A Clinical Study on Efficacy & Safety Profile of Propionyl-L-carnitine Tablets for Peripheral Arterial Diseases
The main objective of this study is to evaluate the effectiveness and safety of the propionyl-L-carnitine hydrochloride tablets among Chinese population in comparison with the placebo, for treatment of the peripheral arterial…
- Trial name
- PLC (NCT00809497)
- Testing
- Propionyl-L-carnitine Tablets
- Where
- China
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Lee's Pharmaceutical Limited
Peripheral Arterial Disease, Chronic Kidney Diseases
Preventing Kidney Injury Using Carbon Dioxide as Contrast Medium in Patients With Peripheral Arterial Disease (PAD) and Chronic Kidney Disease (CKD) Having Arterial Intervention
This research trial will test whether using carbon dioxide as a contrast medium during surgery to open blocked leg arteries can prevent kidney injury.
- Conditions
- Peripheral Arterial Disease, Chronic Kidney Diseases, Acute Kidney Injury
- Trial name
- KID (NCT07891988)
- Testing
- Iodinated contrast medium, CO2 automated injector contrast medium
- Where
- 6 sites in United Kingdom
- Volunteers
- 184 people
- Sponsor
- University of Leicester
Peripheral Artery Disease, Peripheral Vascular Disease
Injection of Autologous CD34-Positive Cells for Critical Limb Ischemia
The purpose of this study is to evaluate the safety and efficacy of intramuscular injections of adult stem cells in patients with Critical Limb Ischemia (CLI).
- Conditions
- Peripheral Artery Disease, Peripheral Vascular Disease, Critical Limb Ischemia
- Trial name
- ACT34-CLI (NCT00616980)
- Testing
- CD34-positive cells, Saline and 5% autologous plasma
- Where
- 12 sites in United States
- Volunteers
- 28 people
- Sponsor
- Losordo, Douglas, M.D.
Popliteal Entrapment Syndrome
Popliteal Artery Entrapment Syndrome & TRanscutaneoUS Oxymetry
Aim of the study is to test the feasibility of transcutaneous oxygen pressure (TcPO2) recording in the diagnosis of popliteal entrapment syndrome (PES) in 30 patients with suspected PES and 30 asymptomatic control heathy subjects
- Trial name
- PETRUS (NCT03356379)
- Testing
- Transcutaneous oximetry
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Ultrasonography, Doppler, Peripheral Arterial Disease
Comparison of Huntleigh Dopplex DMX Digital Doppler Arterial Waveform With the Gold Standard of Ultrasound Duplex Arterial Waveform
NICE guidelines recommend an Ankle brachial pressure index (ABPI) as the primary assessment tool for patients presenting with symptoms or are at a high risk of developing peripheral arterial disease (PAD).
- Trial name
- NCT05373875
- Testing
- Doppler ultrasound
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University Hospitals Bristol and Weston NHS Foundation Trust
Critical Limb Ischemia, Chronic Limb-Threatening Ischemia
PROMISE I Early Feasibility Trial of the LimFlow Stent Graft System
This pilot study will investigate the safety, effectiveness and feasibility of the LimFlow Stent Graft System for creating an AV fistula in the Below The Knee (BTK) vascular system using an endovascular, minimally invasive…
- Trial name
- NCT03124875
- Testing
- LimFlow System
- Where
- 7 sites in United States
- Volunteers
- 32 people
- Sponsor
- LimFlow, Inc.
Peripheral Arterial Disease
Local or Systemic Effects: Mechanisms Related to Arm Crank Exercise - Comparison Between Individuals With and Without PAD
INTRODUCTION: Exercise with an arm ergometer (EB) overcomes the main barrier to physical exercise in patients with Peripheral Artery Disease (PAD), leg pain during walking.
- Trial name
- NCT06828172
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Peripheral Arterial Disease(PAD)
Effects of Virtual Reality Exercises on Individuals With Peripheral Artery Disease
The aim of this study is to investigate the effects of virtual reality exercises on lower extremity skin temperature, arterial stiffness, gait parameters and enjoyment of exercise in individuals with peripheral arterial disease.
- Trial name
- NCT06618131
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Dokuz Eylul University
Chronic Kidney Disease Mineral and Bone Disorder, Cognitive Function
REducing Systemic Inflammation With LOw-dose Colchicine to ImproVE Cardiovascular Calcification in Chronic Kidney Disease: A Pilot Randomized Open-Label Trial
This pilot randomized, open-label, outcome blinded clinical trial is to evaluate the preliminary effects of low-dose Colchicine (LoDoCo) on coronary artery calcification (CAC) progression in adults with chronic kidney disease…
- Conditions
- Chronic Kidney Disease Mineral and Bone Disorder, Cognitive Function, Vascular Calcification, Coronary Artery Calcification
- Trial name
- RESOLVE-CKD (NCT07654231)
- Testing
- Low-dose Colchicine at 0.5mg daily, Usual Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Texas Southwestern Medical Center
Coronary Artery Disease, Cerebral Vascular Disease
Pilot Study: Cardiovascular Events in High Risk Orthopedic Surgical Patients
This is a non-randomized, non-interventional pilot observational study designed to follow high-risk patients through their surgical and hospital stay.
- Conditions
- Coronary Artery Disease, Cerebral Vascular Disease, Peripheral Artery Disease, Renal Insufficiency
- Trial name
- NCT01809730
- Where
- United States
- Sponsor
- NYU Langone Health
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