Clinical trials: Perioperative Care
Surgery, Aging
Preparing Older Adults for Major Surgery With Preoperative Comprehensive Geriatric Assessments
The researchers will conduct observations, interviews, and focus groups with clinicians, staff and patients of the Perioperative Optimization of Senior Health (POSH) clinic, which conducts preoperative comprehensive geriatric…
- Conditions
- Surgery, Aging, Health Care Utilization, Frailty
- Trial name
- NCT06184919
- Testing
- Process Mapping: Observations, Process Mapping: Interviews, Process Mapping: Focus Group
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Wisconsin, Madison
Perioperative Care, Bariatric Surgery
Do Text Message Reminders Increase Preoperative Exercise in Obesity Surgery Candidates?
Preoperative exercise has been shown to improve physiological and functional capacity in patients undergoing abdominal surgery to prepare them for the stress of surgery.
- Conditions
- Perioperative Care, Bariatric Surgery, Obesity
- Trial name
- NCT01607177
- Testing
- Daily text message reminders
- Where
- New Zealand
- Volunteers
- 102 people
- Sponsor
- University of Auckland, New Zealand
Colorectal Disorders
Does a Central Venous Line Reduce Perioperative Fluid Administration?
'Hypothesis-generating' study to assess whether the presence of a central venous line significantly affects the volumes of fluid infused perioperatively in major elective colorectal surgery
- Trial name
- NCT03985111
- Testing
- Central Venous Catheter
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Barts & The London NHS Trust
Congenital Heart Disease in Children
Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures
The incidence of moderate to severe congenital heart disease (CHD) in the United States is estimated to be 6 per 1000 live-born full term infants.
- Trial name
- NCT04604418
- Testing
- No intervention. It is observational
- Where
- 10 sites in United States, Canada
- Volunteers
- 10,000 people
- Sponsor
- Boston Children's Hospital
Prehabilitation, Surgery
'Cardiac and Intramuscular Adaptations Following Short-term Exercise Prehabilitation in Unfit Patients Scheduled to Undergo Hepatic- or Pancreatic Surgery'
Surgery remains an important treatment modality in the treatment of hepatopancreatobiliary (HPB) malignancies, but the physiological stress caused by surgery is at the same time a challenge for the homeostasis of patients.
- Conditions
- Prehabilitation, Surgery, Exercise Prehabilitation, Perioperative Care
- Trial name
- CIRCULATE (NCT05772819)
- Testing
- exercise MRI
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- University Medical Center Groningen
Female, Male
SEx-specific Differences in Cardiac Surgery Patients (SECS).
The aim of this study is to evaluate the differences between females and males undergoing cardiac surgery. The investigators will look at perioperative factors such as adaption of body weight, previous medical history…
- Conditions
- Female, Male, Surgery, Cardiac
- Trial name
- SECS (NCT06554925)
- Testing
- Cardiac surgery
- Where
- Netherlands
- Volunteers
- 10,000 people
- Sponsor
- Jennifer Breel
Spinal Surgery, Post-operative Care
Perioperative Rectal Methadone in Spine Surgery
Patients undergoing spinal surgery require pain control medication after their surgery. Investigators have successfully used intravenous Methadone to manage pain after surgery.
- Conditions
- Spinal Surgery, Post-operative Care, Post-operative Pain Management
- Trial name
- PROMISE (NCT06843174)
- Testing
- Rectal Methadone administer during spinal surgery
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Unity Health Toronto
Perioperative Care, Postoperative Complications
Postoperative Outcomes Within an Enhanced Recovery After Surgery Protocol in Gastric Surgery for Cancer
Methods National audit of a 90-day prospective observational cohort in which postoperative complications will be analyzed at 30 days of follow-up in adult patients undergoing scheduled surgery for gastric resection for cancer…
- Conditions
- Perioperative Care, Postoperative Complications, Gastric Cancer
- Trial name
- POWER4 (NCT03865810)
- Where
- 66 sites in Spain
- Volunteers
- 861 people
- Sponsor
- Grupo Español de Rehabilitación Multimodal
Prehabilitation, Cardiac Surgery
Feasibility of Physical Prehabilitation for High-Risk Patients Undergoing Cardiac Surgery Via Sternotomy
Rationale Cardiac surgery via median sternotomy carries an elevated risk of postoperative complications and delayed functional recovery.
- Conditions
- Prehabilitation, Cardiac Surgery, Risk Assesment, Aortic Valve
- Trial name
- PREPA-STER (NCT07893184)
- Testing
- Physical Prehabilitation Intervention
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Maastricht University Medical Center
Perioperative Medicine, Diabetes (DM)
Adherence to Clinical Guidelines on Perioperative Diabetes Care
Patients who undergo major surgery face a 15-30% risk of serious adverse events, including a 1-5% mortality risk in the first month after surgery.
- Conditions
- Perioperative Medicine, Diabetes (DM), Diabetes Mellitus
- Trial name
- NCT07349199
- Where
- Denmark
- Volunteers
- 13,920 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Gynecologic Disease, Gynecologic Cancer
Enhanced Recovery After Surgery (ERAS) in Gynecological Surgery (ERASGS-01)
Enhanced recovery programs are composed of preoperative, intraoperative and postoperative strategies combined to form a multi-modal pathway.
- Trial name
- ERAS (NCT03629626)
- Testing
- ERAS protocol
- Where
- China
- Volunteers
- 540 people
- Sponsor
- Shandong University
Anesthetics Complications, Anesthetic Toxicity
PK/PD Levobupivacaine with and Without Epinephrine After Ultrasound Guided ESP Block
Currently there is no standardized management or single technique to manage postoperative pain after Video-assisted thoracic surgery (VATS), there are many options available ranging from intravenous opioids, morphine or fentanyl…
- Conditions
- Anesthetics Complications, Anesthetic Toxicity, Bupivacaine Overdose, Nerve Block
- Trial name
- NCT04799184
- Testing
- Levobupivacaine 0.25% with epinephrine 5 ug/ml, Levobupivacaine 0.25% without epinephrine 5 ug/ml
- Where
- Chile
- Volunteers
- 38 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Perioperative Anxiety, Preanesthetic Medication
Handheld-multimedia Versus Oral Midazolam in Pediatric on Perioperative Anxiety
The first goal of this study is to compare the efficacy and safety between anxiolysis by multimedia-distraction with an IPAD versus anxiolysis by premedication with midazolam prior to the induction.
- Conditions
- Perioperative Anxiety, Preanesthetic Medication, Inhalation Anesthesia, Ambulatory Surgery
- Trial name
- NCT04273035
- Testing
- Midazolam oral solution, IPAD
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitair Ziekenhuis Brussel
Critical Illness, Postoperative Complications
General Surgery Patients at the Intensive Care Unit
Introduction: high-risk surgical patients in the intensive care unit (ICU) are a unique population that has yet to be carefully monitored.
- Trial name
- TraViII (NCT06731296)
- Testing
- Presence of a risk factor
- Where
- 2 sites in Colombia
- Volunteers
- 1,000 people
- Sponsor
- Hospital Departamental de Villavicencio
Outcomes Following Major Surgery in Older Adults
The Irish Perioperative OutcomeS (IPOS) Study
The Irish Perioperative OutcomeS (IPOS) Study aims to better understand the factors that influence recovery and outcomes in older adults undergoing major surgery in Ireland.
- Trial name
- IPOS (NCT07895199)
- Volunteers
- 500 people
- Sponsor
- University College Hospital Galway
Perioperative Care
Traditional Versus ScvO2 Guided Perioperative Fluid Therapy
Perioperative goal directed fluid therapy by means of an esophageal doppler has been shown to reduce morbidity and length of stay.
- Trial name
- NCT00468793
- Testing
- Intravenous fluid
- Where
- Norway
- Volunteers
- 240 people
- Sponsor
- Haukeland University Hospital
Post-traumatic Stress Symptoms, Anxiety
Psychological Prehabilitation for Complex Gastrointestinal Surgery
The goal of this clinical trial is to learn if a psychological program before surgery can help adults who have lasting stress from past medical experiences. The program is called PREPARE-GI.
- Conditions
- Post-traumatic Stress Symptoms, Anxiety, Depression Disorder, Gastrointestinal Disease
- Trial name
- PREPARE-GI (NCT07865052)
- Testing
- PREPARE-GI
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Northwestern University
Intestinal Diseases, Intestinal Resection
Implementation of a Pediatric ERAS-based Protocol in Intestinal Resection With Primary Anastomosis
Enhanced Recovery After Surgery (ERAS) is a multimodal perioperative care strategy designed to reduce surgical stress, decrease postoperative complications, and accelerate recovery after surgery.
- Trial name
- PeERAS (NCT07504549)
- Testing
- Standardized Pediatric ERAS-Based Perioperative Protocol
- Where
- 9 sites in Poland
- Volunteers
- 120 people
- Sponsor
- Michał Pasierbek
Anastomotic Leak Small Intestine, Anastomotic Leak Large Intestine
Enhanced Perioperative Care for the Prevention of Colorectal Anastomotic Leakage
This multicenter open-label trial is designed to evaluate if the implementation of an enhanced peri-operative care protocol results in an optimal intraoperative condition of the patient and in a decrease in incidence of…
- Conditions
- Anastomotic Leak Small Intestine, Anastomotic Leak Large Intestine, Anastomotic Leak Rectum, Intraoperative Awareness
- Trial name
- DOUBLE CHECK (NCT05250882)
- Testing
- Enhanced perioperative care protocol
- Where
- 9 sites in Belgium, Netherlands
- Volunteers
- 1,600 people
- Sponsor
- Amsterdam UMC, location VUmc
Breast Cancer, Postoperative Recovery
ERAS Protocols in Breast Conserving Surgery
Enhanced Recovery After Surgery (ERAS) protocols have been of increasing interest in the surgical community for decades. The emphasis has been development of protocols to maximize pain control post-operatively without the use of…
- Trial name
- ERAS (NCT06938581)
- Testing
- ERAS Protocol, Standard Perioperative Care
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- University of Nebraska