Clinical trials: Perioperative Anesthetic
Otitis Media With Effusion (OME)
Retrospective Analysis of Perioperative Anesthetic Care and Analgesia Management of Patient Undergoing Bilateral Myringotomy With Tube Insertion
This is a retrospective chart review. The purpose of this study is to retrospectively examine the use of perioperative analgesics on the incidence of postoperative pain and emergence delirium in patients undergoing bilateral…
- Trial name
- NCT02409693
- Testing
- Myringotomy with tube insertion
- Sponsor
- Nationwide Children's Hospital
Colorectal Disorders, Regional Anesthesia Morbidity
Transversus Abdominis Plane Blocks With and Without Dexamethasone
Dexamethasone will be used as an adjunct to local anesthetics (bupivacaine) to prolong the duration of laparoscopically-placed transversus-abdominis plane blocks in elective colorectal resection.
- Conditions
- Colorectal Disorders, Regional Anesthesia Morbidity, Analgesia, Local Anesthetic Complication
- Trial name
- TAP-DEX (NCT05432934)
- Testing
- Dexamethasone
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Pain, Constipation
Effect of Lidocaine and Esmolol to Improve the Quality of Recovery
The purpose of this prospective, randomized, double-blinded, active-controlled study is: To assess the effectiveness of systemic administration of lidocaine and esmolol in combination (vs.
- Conditions
- Pain, Constipation, Nausea, Vomiting
- Trial name
- NCT01114997
- Testing
- Lidocaine, Esmolol, Lidocaine + Esmolol (Combo)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Cedars-Sinai Medical Center
Regional Anesthesia, Lidocaine Infusion
Perioperative Use of Erector Spinae Plane Block (ESPB) and Intravenous Lidocaine Infusion in Anesthetic Management of Spinal Surgery in Children
Testing the hypothesis that in children undergoing spinal surgery, ESP-block will increase the time to emergency anesthesia in the postoperative period compared with intravenous lidocaine infusion.
- Trial name
- NCT06965933
- Testing
- ESP block group, IV Lidocaine
- Where
- Russia
- Volunteers
- 68 people
- Sponsor
- Saint Petersburg State University, Russia
Opioid Use, Cytokine
Cranial Electrotherapy Stimulation on Anesthetics Consumption and Postoperative Pain
Cranial electrotherapy stimulation (CES) is a non-invasive intervention to treat anxiety, depression, insomnia, and pain. But clinical studies and applications of CES in relation to acute postoperative pain are few.
- Trial name
- NCT03825471
- Testing
- electrotherapy, Opioid Anesthetics, colon cancer surgery
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Breast Neoplasms, Surgery Scheduled
Proof of Concept of the Aiinane Preoperative Risk Assessment Tool.
BACKGROUND: Each year, over 13,000 patients in Catalonia and more than 4 million worldwide experience last-minute surgery cancellations (LMC) due to preoperative inefficiencies.
- Conditions
- Breast Neoplasms, Surgery Scheduled, Surgery Related Complications Rate, Preanesthetic Medication
- Trial name
- aiinane-24-1 (NCT07021235)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Ancor Serrano
Video Assisted Thoracic Surgery (VATS)
Comparison Effects of Three Regional Anesthetic Technique on Pain During Video-assisted Thorascopic Surgery(VATS)
In this study, our iş to compare effect of erector spinae plan block(ESP), paravertebral block(PVB) and mid-point transverse process to pleura block(MTP) on perioperative pain measured with analgesia nociceptive index monitor on…
- Trial name
- NCT06689449
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- TC Erciyes University
Smoking ( Cigarette)
Effectiveness of Brief Smoking Cessation Counselling in Pre-Anaesthesia Assessment Clinic
The goal of this clinical trial is to evaluate whether a brief, nurse-delivered smoking cessation intervention can increase pre-operative smoking abstinence and improve perioperative outcomes among adult elective surgical…
- Trial name
- NCT07505147
- Testing
- Nurse-led AWARD brief smoking cessation counselling with active referral and tailored perioperative booklet in the pre-anaesthetic assessment clinic, Usual pre-anaesthetic care without structured smoking cessation
- Where
- Hong Kong
- Volunteers
- 125 people
- Sponsor
- Pok Oi Hospital
Arthroscopic Surgery
Effectiveness of Per-Operative Bupivicaine in Reducing Postoperative Pain at Port Site and Improving Mobility in Knee Arthoscopic Procedures
The investigator's aim is to evaluate the effectiveness of per-operative bupivacaine infiltration at arthroscopic port sites in reducing post-operative pain compared to placebo in patients undergoing knee arthroscopic procedures.
- Trial name
- NCT07090928
- Testing
- 5 ml of 0.5% bupivacaine infiltrated at each port site
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Khyber Teaching Hospital
Anesthetics Complications, Anesthetic Toxicity
PK/PD Levobupivacaine with and Without Epinephrine After Ultrasound Guided ESP Block
Currently there is no standardized management or single technique to manage postoperative pain after Video-assisted thoracic surgery (VATS), there are many options available ranging from intravenous opioids, morphine or fentanyl…
- Conditions
- Anesthetics Complications, Anesthetic Toxicity, Bupivacaine Overdose, Nerve Block
- Trial name
- NCT04799184
- Testing
- Levobupivacaine 0.25% with epinephrine 5 ug/ml, Levobupivacaine 0.25% without epinephrine 5 ug/ml
- Where
- Chile
- Volunteers
- 38 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Alarm Fatigue, Perioperative
Intraoperative Cognitive Load in Anesthesia Nurses Across Anesthetic Phases
The goal of this observational study is to measure the cognitive load (mental effort) of anesthesia nurses during real surgical procedures at Hospital Clínic de Barcelona, Spain.
- Conditions
- Alarm Fatigue, Perioperative, Patient Safety, Cognitive Load
- Trial name
- ENCOPER (NCT07568158)
- Testing
- NASA Task Load Index (NASA-TLX)
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Alzheimers Disease, Postoperative Delirium
Markers of Alzheimers Disease and Cognitive Outcomes After Perioperative Care
This study will examine the hypothesis that changes in the cognition (i.e. thinking and memory) after anesthesia and surgery are correlated with changes in markers of Alzheimers Disease in the fluid around the brain and spinal…
- Conditions
- Alzheimers Disease, Postoperative Delirium, Post Operative Cognitive Dysfunction
- Trial name
- MADCO-PC (NCT01993836)
- Testing
- Total intravenous anesthesia with propofol, General anesthesia with isoflurane
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- Duke University
Coronary Artery Disease
TEAM-Project: Trial on the Effect of Anesthetics on Morbidity and Mortality
Volatile anesthetics may provide some protection from myocardial ischemia, an effect called anesthetic preconditioning. In patients undergoing coronary artery bypass surgery, this preconditioning effect resulted in better cardiac…
- Trial name
- NCT00286585
- Testing
- Inhalational anesthetic, Intravenous anesthetic, propofol
- Where
- 3 sites in Switzerland
- Volunteers
- 385 people
- Sponsor
- University Hospital, Basel, Switzerland
Lumbar Spine Disease, Lumbar Disc Herniation
Perioperative Local Anesthesia Block in Spine Surgery
The purpose of the this study to evaluate the feasibility, safety, and efficacy of a fluoroscopically-guided dorsal ramus block placed by the operative neurosurgeon prior to lumbosacral surgery.
- Conditions
- Lumbar Spine Disease, Lumbar Disc Herniation, Lumbar Spinal Stenosis
- Trial name
- NCT05094427
- Testing
- Preoperative fluoroscopically-guided dorsal ramus block placed by the operative neurosurgeon
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- Columbia University
Oncologic Surgery, Cancer
Optimal Perioperative Pain Control in Minimally Invasive Abdominal Cancer Surgery
This is a research study to evaluate the effectiveness of 3 different types of routine pain management regimens used during clinically indicated, minimally invasive oncologic (cancer) surgery.
- Conditions
- Oncologic Surgery, Cancer, Cancer Surgery, Hepatic Cancer
- Trial name
- LapTAP (NCT06731998)
- Testing
- Local Anesthesia, Laparoscopic Transversus Abdominis Plane block
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Perioperative Anesthetic, Anxiety
Effect of a Preoperative Educational Video on Anxiety Levels
Preoperative anxiety is common among patients undergoing elective surgery and may negatively affect perioperative outcomes. This randomized controlled trial aims to evaluate the effectiveness of a short educational video in…
- Trial name
- PEVA (NCT07679659)
- Testing
- QR Code Video, Tablet Video
- Volunteers
- 360 people
- Sponsor
- Aksaray University Training and Research Hospital
Colectomy, Open Surgery
Perioperative Intravenous Nimodipine Trial
The role of perioperative IV administration of nimodipine, an L-type calcium channel antagonist which is capable of crossing the blood-brain barrier, on peri-operative opioid and anesthetics requirements, pain intensity…
- Conditions
- Colectomy, Open Surgery, Pain, Pain, Postoperative
- Trial name
- NCT07048522
- Testing
- Nimodipine, Isotonic Saline
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- University of Ioannina
Cardiovascular Diseases, Respiratory Diseases
Need for the Assessment and Consultation Team (ACT) Following Anesthetic Care
The goal of this study was to identify the etiology of events and demographics of patients that experience complications requiring activation of the Rapid Response Team (RRT) during the first 24 h following anesthetic care.
- Conditions
- Cardiovascular Diseases, Respiratory Diseases, Neurologic Diseases
- Trial name
- NCT02754947
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Nationwide Children's Hospital
Preoperative Care
Prospective Validation of an Artificial Intelligence Tool for Pre-Anesthetic Assessment
This prospective observational cohort study aims to validate an artificial intelligence (AI) tool designed for pre-anesthetic assessment in Portuguese, tailored to the Brazilian healthcare context.
- Trial name
- NCT07290647
- Testing
- AI-based pre-anesthetic assessment, Anesthesiologist-led pre-anesthetic evaluation
- Where
- Brazil
- Volunteers
- 270 people
- Sponsor
- Hospital Nossa Senhora da Conceicao
Gastrostomy
Transversus Abdominis Plane Block on Stress Response
This study evaluates the effect of transversus abdominis plane(TAP) block combined with general anesthesia on perioperative stress response in patients undergoing radical gastrectomy.
- Trial name
- NCT03035916
- Testing
- Transversus abdominis plane block, Epidural anesthesia, control
- Where
- China
- Volunteers
- 91 people
- Sponsor
- Jilin University