Clinical trials: Perioperative Analgesia
Analgesia
Analgesia for Perineal Surgeries in High-risk Pediatric Patients
Perioperative pain management in pediatric patients, especially for anorectal and penile surgeries, presents significant challenges for anesthetists.
- Trial name
- NCT07602894
- Testing
- Systemic analgesia, Sacral multifidus plane block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Tonsillitis
Celecoxib as a Post-tonsillectomy Pain Medication
The hypothesis is that celecoxib effectively reduces pain after a tonsillectomy and reduces post-operative narcotic use. To test this hypothesis, the study is placebo controlled (sugar pill).
- Trial name
- NCT00583453
- Testing
- Celecoxib
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Iowa
Spinal Surgery, Pain Intensity
Dexmedetomidine-esketamine Combination and Moderate-to-severe Pain After Spinal Surgery
Spinal surgery is generally followed by severe postoperative pain, and poor pain control may cause adverse outcomes such as cardiovascular events, neurocognitive disorders, and chronic postsurgical pain (CPSP).
- Conditions
- Spinal Surgery, Pain Intensity, Dexmedetomidine, Esketamine
- Trial name
- NCT07523321
- Testing
- Combined dexmedetomidine-esketamine administration
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Peking University First Hospital
Post Operative Pain, Hyperalgesia
Perioperative Opioid-induced Hyperalgesia and Its Prevention With Ketamine and Methadone
Background: In perioperative period inhibition of N-Methyl-D-Aspartate receptor prevents opioid-induced hyperalgesia and reduce postoperative opioid requirement after abdominal surgery.
- Trial name
- NCT01594047
- Testing
- ketamine infusion, Methadone PCA
- Where
- Italy
- Volunteers
- 113 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Hip Fractures, Ultrasound-guided Nerve Block
Fascia Iliaca Compartment Block and Tramadol for Analgesia in Hip Fracture
Hip fractures are a growing public health concern globally due to the aging population, with high incidence and significant mortality rates one year post-fracture.
- Conditions
- Hip Fractures, Ultrasound-guided Nerve Block, Perioperative Analgesia
- Trial name
- NCT06728033
- Testing
- supra-inguinal fascia iliaca compartment block, Tramadol
- Where
- China
- Volunteers
- 240 people
- Sponsor
- West China Hospital
Hip Fractures, Perioperative Myocardial Ischemia
Lumbar Plexus Block Upon the Incidence of Ischemic Cardiovascular Events in Elderly Patients With Hip Fracture
The purpose of this study is evaluate the efficacy of perioperative continuous lumbar plexus block in reducing the risk of cardiac ischemic events of elderly patients undergoing surgery for hip fractures, expressed as a reduction…
- Trial name
- NCT01961895
- Testing
- Continuous lumbar plexus (LP) block analgesia, Intravenous patient-controlled analgesia
- Where
- 2 sites in Chile
- Volunteers
- 31 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Paravertebral Block
COMPARISON OF ERECTOR SPINA PLAN BLOCK AND THORACIC PARAVERTEBRAL BLOCK FOR PERIOPERATIVE ANALGESIA
The primary aim of this study was to compare the postoperative analgesic efficacy of thoracic paravertebral block with erector spinae plane block, which we use in thoracotomy surgeries.
- Trial name
- A Two-Center (NCT07021651)
- Testing
- Erector Spinae Plane (ESP) block admistring, Thoracic Paravertebral Block administring
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Pain, Postoperative
Analgesic Efficacy of Plan Blocks in Laparoscopic Hysterectomies
Hysterectomy is the most common major intervention in gynecology after cesarean section. Indications include myoma uteri, abnormal uterine bleeding, cervical intraepithelial neoplasia, chronic pelvic pain, uterine uteri, operated…
- Trial name
- NCT05925972
- Testing
- Plane block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Perioperative Care, Chronic Post-operative Pain
Optimized Acute Pain Control With Parecoxib in Uniportal Video-assisted Thoracoscopic Surgery.
Chronic pain after thoracic surgery has been a bothering problem since the era of thoracotomy. The prevalence of chronic pain no matter in thoracotomy or video-assisted thoracoscopic surgery is about 30 to 47%.
- Trial name
- NCT05150431
- Testing
- Parecoxib
- Where
- Taiwan
- Volunteers
- 58 people
- Sponsor
- National Taiwan University Hospital
Anesthesia
Fentanyl Versus Morphine in Spinal Anesthesia for Caesarian Section - Study on Analgesia, Side Effects and Patient 's Satisfaction
Intrathecal morphine and fentanyl are used for anesthesia and perioperative pain management in caesarian section. Despite the fact that spinal Fentanyl is better tolerated, might not be enough for postoperative pain control.
- Trial name
- FvMinSA (NCT05533229)
- Testing
- Fentanyl, Morphine
- Where
- Romania
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Dr. Mihai Octavian Botea
Arthroscopic Surgery
Effectiveness of Per-Operative Bupivicaine in Reducing Postoperative Pain at Port Site and Improving Mobility in Knee Arthoscopic Procedures
The investigator's aim is to evaluate the effectiveness of per-operative bupivacaine infiltration at arthroscopic port sites in reducing post-operative pain compared to placebo in patients undergoing knee arthroscopic procedures.
- Trial name
- NCT07090928
- Testing
- 5 ml of 0.5% bupivacaine infiltrated at each port site
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Khyber Teaching Hospital
Osteoarthritis
Perioperative Pain Control With Celecoxib (Celebrex) in Total Knee Arthroplasty
We propose that administration perioperative celecoxib is effective to control postoperative VAS pain scores, improve rehabilitation results, and decrease narcotics usage in total knee replacement patients.
- Trial name
- NCT00598234
- Testing
- Celecoxib (Celebrex)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Postoperative Pain
Thoracic Paravertebral Block Versus IV Fentanyl Infusion
High-quality analgesia during and following cardiac surgery is infrequently obtained, Sternotomy and thoracotomy is associated with significant pain that resulte in hypoventilation, atelectasis, and hypoxemia,Pain management is…
- Trial name
- NCT03903367
- Testing
- Fentanyl Citrate
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Beni-Suef University