Clinical trials: Perioperative
Post Operative Analgesia, Bariatric Surgery
Oral Acetaminophen for Post-Op Pain Management in Bariatric Surgery Patients
Adult patients with morbid obesity who have had Roux-en-Y gastric bypass (RYGB) or laparoscopic sleeve gastrectomy (LSG) surgery have impaired drug metabolism.
- Conditions
- Post Operative Analgesia, Bariatric Surgery, Bariatric Surgery (Gastric Bypass), Bariatric Surgery Patients
- Trial name
- NCT06658574
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Rutgers, The State University of New Jersey
Perioperative Optimization
Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated Data
This REMAP Periop ERP domain study falls under the Periop Core Protocol, which compares the different recommended strategies for enhancing recovery through the use of various standard of care treatments before, during and after…
- Trial name
- NCT04606264
- Testing
- Neuraxial Analgesia, Regional Block 1: Paravertebral, Perphenazine
- Where
- 3 sites in United States
- Volunteers
- 3,395 people
- Sponsor
- Jennifer Holder-Murray
Pelvic Organ Prolapse, Perioperative/Postoperative Complications
Preoperative Gabapentin vs Placebo for Vaginal Prolapse Surgery
This study will recruit women scheduled to undergo vaginal apical suspension surgery (either uterosacral ligament suspension or sacrospinous ligament fixation) with or without other prolapse or anti-incontinence procedures.
- Trial name
- NCT05658887
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Joseph Kowalski
Pediatric Perioperative Blood Pressure Management
Assessment of Efficacy, Safety and Dosing of Clevidipine in Pediatric Participants Undergoing Surgery (PIONEER)
Evaluate the efficacy, safety, and dosing of clevidipine as an intravenous (IV) infusion for blood pressure (BP) management in paediatric participants in the perioperative setting.
- Trial name
- PIONEER (NCT01938547)
- Testing
- clevidipine
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Surgery, Surgery--Complications
Telemedicine Control Tower for the Operating Room: Navigating Information, Care and Safety
Medical errors account for thousands of potentially preventable deaths each year. With the annual increase of surgical cases there is a need for research into the potential utility of a telemedicine-based control center for the…
- Conditions
- Surgery, Surgery--Complications, Perioperative/Postoperative Complications
- Trial name
- TECTONICS (NCT03923699)
- Testing
- Anesthesia Control Tower monitoring
- Where
- United States
- Volunteers
- 79,560 people
- Sponsor
- Washington University School of Medicine
Perioperative/Postoperative Complications
Feasibility of a New Ambulatory Multi-vital Signs Monitor
The purpose of this research is evaluate vital signs (VS), which include non-invasive blood pressure, pulse rate, respiratory rate and Oxygen Saturation (SpO2) using a portable wrist monitoring device called a Caretaker.
- Trial name
- NCT05562011
- Testing
- Caretaker Device placement
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Wake Forest University Health Sciences
Perioperative Complication
Perioperative Morbidity in Elective Surgery Based on the Time of the Year
This is a retrospective cohort study using Electronic Privacy Identification Center (EPIC) database to evaluate if there are any differences in perioperative morbidity for elective surgery based on the time of the year surgery is…
- Trial name
- NCT02958293
- Volunteers
- 19,872 people
- Sponsor
- TriHealth Inc.
Perioperative Care, Surgery--Complications
Perioperative Hypothermia and Myocardial Injury After Non-cardiac Surgery
We propose to test the hypothesis that aggressive warming reduces the incidence of major cardiovascular complications, compared to routine care.
- Conditions
- Perioperative Care, Surgery--Complications, Hypothermia; Anesthesia, Myocardial Injury
- Trial name
- PROTECT (NCT03111875)
- Testing
- aggressive warming, routine thermal management
- Where
- 11 sites in United States, China
- Volunteers
- 5,056 people
- Sponsor
- The Cleveland Clinic
Breast Cancer, Perioperative/Postoperative Complications
Fibrin Sealant in Preventing Fluid Build Up During Surgery in Patients Undergoing Breast Reconstruction
The purpose of this study is to investigate the efficacy of an alternative surgical technique and the use of fibrin sealant in preventing post-operative seroma formation.
- Trial name
- NCT01649505
- Testing
- fibrin sealant (Beriplast P, TISSEEL VH), breast reconstruction
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- OHSU Knight Cancer Institute
Cervical Cancer, Endometrial Cancer
Standard Versus Intensity-Modulated Pelvic Radiation Therapy in Treating Patients With Endometrial or Cervical Cancer
RATIONALE: Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells. Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause…
- Conditions
- Cervical Cancer, Endometrial Cancer, Gastrointestinal Complications, Perioperative/Postoperative Complications
- Trial name
- NCT01672892
- Testing
- Standard radiation therapy, intensity-modulated radiation therapy
- Where
- 137 sites in United States, Canada and 2 more
- Volunteers
- 289 people
- Sponsor
- Radiation Therapy Oncology Group
Nephrolithiasis, Urolithiasis
Perioperative Pregabalin in Ureteroscopy: a Pilot
The investigators propose a pilot clinical trial on the use of perioperative pregabalin in order to decrease ureteral stent related symptoms and decrease opioid usage after ureteroscopy with stent placement.
- Conditions
- Nephrolithiasis, Urolithiasis, Perioperative/Postoperative Complications, Pain, Postoperative
- Trial name
- NCT03927781
- Testing
- Pregabalin 300mg
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Missouri-Columbia
Pain, Perioperative
Study To Investigate The Effectiveness Of Pregabalin For Management Of Patients Undergoing Total Hip Replacement
The purpose of this study is the investigate if pregabalin started a day before surgery and continued for 14 days post-operatively can reduce post-operative pain, relieve pre- and post-operative anxiety and sleep disturbances.
- Trial name
- NCT00905437
- Testing
- Pregabalin
- Where
- 7 sites in India
- Volunteers
- 72 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Perioperative Chest Pain
Lidocaine 5% Patch (Lidoderm) for the Prevention of Acute and Chest Pain Following Robotic Valve Surgery
The post-thoracotomy pain (PTP) has been defined as persistent or recurrent pain that lasts for at least 2 month after thoracotomy and is associated with surgical incision or its intercostal nerve cutaneous distribution.
- Trial name
- NCT03120351
- Testing
- Lidoderm 5 % Topical Patch
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The Cleveland Clinic
Postoperative Cardiac Complication, Heart Failure
More Options Available With a Quadripolar LV Lead pRovidE In-clinic Solutions to CRT Challenges
This investigation is designed with the hypothesis that using a quadripolar left ventricular lead results in less interventions when dealing with high pacing thresholds and Phrenic Nerve Stimulation (PNS), both at implant and…
- Conditions
- Postoperative Cardiac Complication, Heart Failure, Left Ventricular Cardiac Dysfunction, Inappropriate Phrenic Nerve Stimulation
- Trial name
- MORE-CRT (NCT01510652)
- Testing
- BiP Group, Quad Group
- Where
- 64 sites in Belgium, Canada and 11 more
- Volunteers
- 1,078 people
- Sponsor
- Abbott Medical Devices
Perioperative Inflammatory Response
Assessing the Role of "Statin" Therapy and Perioperative Inflammatory Response in Patients Undergoing Major Orthopedic Surgery
The purpose of the present study is to quantify the degree of modulation, if any, in the perioperative inflammatory response associated with statins use.
- Trial name
- NCT00656292
- Testing
- Simvastatin
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Mayo Clinic
Inflammation, Perioperative Morbidity
The Effects of Corticosteroids, Glucose Control, and Depth-of-Anesthesia on Perioperative Inflammation and Morbidity From Major Non-cardiac Surgery (Dexamethasone, Light Anesthesia and Tight Glucose Control (DeLiT Trial))
Evidence thus suggests that steroid administration, tight glucose control, and avoidance of deep anesthesia may decrease perioperative morbidity by reducing the inflammatory response to surgery.
- Trial name
- NCT00995501
- Testing
- Dexamethasone Sodium Sulfate, Insulin, anesthesia management
- Where
- United States
- Volunteers
- 381 people
- Sponsor
- d sessler
Perioperative Hypothermia
Prospective Trial of the Effect of Preoperative Forced-air Warming on Perioperative Body Temperature Following Neuraxial Anesthesia in Total Hip Arthroplasty Patients
The purpose of this study is to determine if placement of a forced-air warming device prior to institution of regional anesthesia improves perioperative temperature control in patients undergoing total hip arthroplasty.
- Trial name
- NCT01626690
- Testing
- Bair-Paws Warming Device, Bair-Hugger Warming Device
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Wisconsin, Madison
Perioperative Hyperoxygenation, Wound Infection
Effect of Peri-operative Supplemental Oxygen in Wound Infection After Appendectomy
The study evaluates the role of supplemental hyper-oxygenation given perioperatively on wound site infection after appendectomy.
- Trial name
- NCT02687217
- Testing
- oxygen
- Volunteers
- 60 people
- Sponsor
- Lady Hardinge Medical College
Reduction of Length of Hospitality Stay, Reduction of Perioperative Complications
GDT by Cardiac Index Trending Via a Radial Arterial Line in General Surgery
This is a multi-Center, prospective, randomized Outcome Study comparing continuous cardiac index trending via a radial arterial line versus standard care in general surgical patients
- Trial name
- NCT01401283
- Testing
- measurement of cardiac output and pulse pressure variation
- Where
- Germany
- Volunteers
- 160 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Inadvertent Perioperative Hypothermia, Preoperative Anxiety Experienced by the Patient
Evaluation of Core Body Temperature When Using Forced Air Warming or an Active Blanket to Prevent Perioperative Hypothermia
This investigation is undertaken to investigate if patient warming with BARRIER® EasyWarm active self-warming blanket differs compared to active warming with forced air warming in terms of core body temperature perioperatively.
- Trial name
- NCT02079311
- Testing
- Active self warming blanket, Forced air warming device
- Where
- 3 sites in Germany, Norway and 1 more
- Volunteers
- 55 people
- Sponsor
- Molnlycke Health Care AB