Clinical trials: Perioperative/Postoperative Complications
Urologic Cancer, Prostate
Comparison of the Integrated Posterior-Anterior-Lateral Approach and the Posterior Approach in Robotic Radical Prostatectomy
This study aims to compare perioperative, pathological, and early functional outcomes of PAL （Posterior, Anterior and Lateral）combined approach RARP and posterior approach (with Retzius space preserved) RARP in the treatment of…
- Conditions
- Urologic Cancer, Prostate, Robot Assisted Laparoscopic Radical Prostatectomy
- Trial name
- NCT07305142
- Testing
- PAL combined approach group, posterior approach group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Perioperative/Postoperative Complications
Remote Ischemic Preconditioning Before Abdominal Surgery
Major abdominal surgeries are associated with perioperative cardiac morbidity of up to 10%. Ischemic preconditioning may have a protective effect.
- Trial name
- NCT01340742
- Testing
- Remote Ischemic Pre-conditioning, Control
- Where
- Canada
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cardiac Surgical Procedures, Blood Transfusion
Systematic Intraoperative Cell Salvage in On-Pump Cardiac Surgery Within a Mature Patient Blood Management Programme
The goal of this observational study is to learn if cell salvage lowers the need for donor blood in adults having planned heart surgery with a heart-lung machine.
- Conditions
- Cardiac Surgical Procedures, Blood Transfusion, Anemia, Postoperative Hemorrhage
- Trial name
- SPARE (NCT07922486)
- Testing
- Systematic intraoperative cell salvage
- Where
- Portugal
- Volunteers
- 657 people
- Sponsor
- Aveiro University
Peptic Ulcer Perforation, Perforated Bowel
ERAS vs Conventional Approach in Peptic Perforation-RCT
This study compares 2 different ways of perioperative management in patients of peptic perforation. Experimental arm is the ERAS arm( Enhanced recovery after surgery) and the comparative arm is Conventional arm.
- Conditions
- Peptic Ulcer Perforation, Perforated Bowel, Post-Op Complication, Emergencies
- Trial name
- ERASE (NCT04194060)
- Testing
- Enhanced Recovery after Surgery group, Conventional
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Preoperative Care, Anxiety
Perioperative Effects of Operating Room Virtual Tour
Preoperative anxiety is associated with adverse consequences such as emergence delirium, and postoperative behavioral changes. According to previous studies, providing information of anesthetic procedures helps to lessen…
- Conditions
- Preoperative Care, Anxiety, Emergence Delirium, Postoperative Complications
- Trial name
- NCT03172182
- Testing
- a 360-degree VR video tour
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Bundang Hospital
Smoking Cessation, Perioperative/Postoperative Complications
Perioperative Smoking Cessation Interventions
To assess impact of behavioral economic principles of precommitment, implementation intentions, and social contracting on smoking cessation for patients undergoing surgery.
- Trial name
- NCT03222908
- Testing
- Intervention1: Contract Agreement, Intervention2: Implementation Intentions
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Duke University
Opioid Use, Unspecified, Pain, Postoperative
Influence of Nociception Level Monitor (NOL) Guided Analgesic Delivery on Robot-assisted Colorectal Surgery
Being relatively new, the NOL monitor may offer interesting observations in perioperative nociception levels and appropriate analgesic consumption in diverse surgeries, including robot-assisted surgery.
- Trial name
- NCT05662371
- Testing
- Nociception Level monitor (NOL), Standard care
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Southern Denmark
Quality of Recovery
Can Simple Perioperative Measures Improve Quality of Recovery Following Ambulatory Laparoscopic Surgery in Females?
The aim of this study was to assess whether it was possible to improve patients' self-assessed quality of recovery and reduce the level of post-operative nausea and vomiting in female patient undergoing laparoscopic…
- Trial name
- NCT03825666
- Testing
- ProvideXtra® Fresenius Kabi
- Volunteers
- 74 people
- Sponsor
- Danderyd Hospital
Perioperative Care, Postoperative Complications
Postoperative Outcomes Within an Enhanced Recovery After Bariatric Surgery Protocol
Methods National audit of a 90-day prospective observational cohort in which pre-defined postoperative complications were analyzed at 30 days of follow-up in adult patients undergoing elective bariatric surgery with or without an…
- Conditions
- Perioperative Care, Postoperative Complications, Bariatric Surgery Candidate
- Trial name
- POWER3 (NCT03864861)
- Where
- 53 sites in Spain
- Volunteers
- 460 people
- Sponsor
- Grupo Español de Rehabilitación Multimodal
Postoperative Delirium, Postoperative Cognitive Dysfunction
The Impact of Repetitive Transcranial Magnetic Stimulation on the Prognosis of Elderly Surgical Patients
Exploring the effects of repeated transcranial magnetic stimulation (rTMS) during the perioperative period on the incidence of postoperative delirium, postoperative cognitive dysfunction, and chronic postoperative pain in elderly…
- Conditions
- Postoperative Delirium, Postoperative Cognitive Dysfunction, Chronic Post-surgical Pain
- Trial name
- NCT06392919
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Affiliated Hospital of Nantong University
Postoperative Pain
Effects of Perioperative Intravenous Lidocaine and Ketamine on Acute and Chronic Pain After Open Nephrectomy
Open nephrectomy is one of the most common surgical procedures in urologic practice. Pain after surgery remains a significant clinical problem as it impairs recovery adversely and may lead to the transition to chronic pain.
- Trial name
- NCT02653651
- Testing
- Ketamine, Lidocaine
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Tunis El Manar
Shock, Surgical, Shock
Angiotensin II in the Perioperative Management of Hypotension in Kidney Transplant Recipients
The current standard of catecholamine vasopressor management of perioperative hypotension in kidney transplant patients carries significant risks and falls short in many ways.
- Conditions
- Shock, Surgical, Shock, Hypotension and Shock, Kidney Transplant; Complications
- Trial name
- NCT04529005
- Testing
- Angiotensin II
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Illinois Chicago
General Anesthetic Drug Adverse Reaction, Perioperative/Postoperative Complications
Observational of Emergence Time Between Patients Receive General Anesthesia With BIS or Spectrogram EEG Monitor
The bispectral index parameter is used to guide the titration of general anesthesia, however; conflicting results between different studies cannot prove the benefit of EEG monitor on improvement of OR efficiency.
- Trial name
- NCT05208502
- Testing
- DSA monitor
- Where
- Taiwan
- Volunteers
- 126 people
- Sponsor
- National Taiwan University Hospital
Post-operative Pain
Comparing Perioperative Outcomes in Pain Control
This project consists of a randomized controlled study design. Study candidates will include all patients 18 years or older, who were evaluated at UCSD and found to have an orthopaedic injury requiring surgery.
- Trial name
- NCT05690282
- Testing
- Multimodal Pain Management (Ibuprofen/Acetaminophen/GABAPentin/0.25%Bupivacaine)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer
Multimodal Prehabilitation and Rehabilitation for Men Undergoing Robot-Assisted Radical Prostatectomy
Prostate cancer is the most common cancer in Australian men. Robot-assisted radical prostatectomy (RARP) - surgical removal of the prostate - is a standard treatment, but it frequently causes erectile dysfunction (ED) and urinary…
- Conditions
- Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer, Urinary Incontinence Following Surgical Procedure
- Trial name
- ROBOPREP (NCT07576335)
- Testing
- Tadalafil 5 mg, Pelvic Floor Muscle Training (PFMT), Aerobic Exercise Program
- Where
- 3 sites in Australia
- Volunteers
- 64 people
- Sponsor
- Surgical Outcomes Research Centre (SOuRCe)
Hip Fractures, Malnutrition
Postoperative Dietary Intake of Hip Fracture Patients
The goal of this observational study is to observe the postoperative dietary intake in older adult hip fracture patients from their day of surgery (day zero) until day three inclusive.
- Conditions
- Hip Fractures, Malnutrition, Comorbidities and Coexisting Conditions, Postoperative Complications
- Trial name
- NCT06451679
- Testing
- Observational
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Teesside University
Colo-rectal Cancer
Impact of Pre- and Post-operative Serum Metabolome Dynamics in Colorectal Resection Outcomes
The aim of this study is to systematically analyze the dynamic pattern of preoperative and postoperative serum metabolites in colorectal cancer patients through metabolomics technology, and to screen the key metabolites with…
- Trial name
- NCT07035262
- Testing
- serum metabolites
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Dong Peng
Hypothermia
Study to Determine the Effects of Pre-warming on OR Patient Temperatures and Surgical Outcomes
The application of active warming to patients whether awake or under general anesthesia has been proven safe in numerous studies and it is common practice to use warmers.
- Trial name
- NCT02177903
- Testing
- Bair Paws Patient Adjustable Warming System
- Where
- Canada
- Volunteers
- 220 people
- Sponsor
- Solventum US LLC
Postoperative Pain, Analgesia
Perioperative Multimodal Analgesia for Supratentorial Craniotomy
This randomized clinical trial aims to evaluate the effectiveness of scalp nerve blocks and dexmedetomidine in reducing opioid use and preventing postoperative delirium in patients undergoing supratentorial brain tumor surgery.
- Conditions
- Postoperative Pain, Analgesia, Supratentorial Brain Tumor
- Trial name
- NCT07441421
- Testing
- Dexmedetomidine, Scalp-Nerve Block
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Tiantan Hospital
Postoperative Pain
Effect of Perioperative Hypothermia on Postoperative Pain
This study aims to observe the impact of perioperative body temperature on postoperative pain and pain sensitization for the patients with laparoscopic surgery.
- Trial name
- NCT05681091
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University