Clinical trials: Periodontal Intrabony Defects
Periodontitis, Adult, Intrabony Periodontal Defect
The Flapless Approach in Periodontal Regeneration
The present investigation is designed in order to compare the radiographic and clinical effectiveness of flapless procedure performed alone or in combination with enamel matrix derivatives in the periodontal regenerative…
- Trial name
- NCT05456555
- Testing
- Flapless with Enamel Matrix Derivatives (EMD), Flapless without Enamel Matrix Derivatives (EMD)
- Where
- Italy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Periodontal Pocket
Gingival Crevicular Fluid Bone Morphogenetic Protein - 2 Release Profile Following the Use of Perforated Membrane
One of the most important elements suggested to be provided through membrane perforations to augment regeneration are cell released growth factors from the overlying periosteal and gingival cells.
- Trial name
- MPM (NCT01860495)
- Testing
- perforated membrane, G2
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Intrabony Periodontal Defect
Evaluation of Autogenous Demineralized Dentin Graft Vs Autogenous Bone Graft in Management of Intrabony Defects
The main goal is to evaluate and compare the clinical and radiographic efficacy of autogenous demineralized dentin as bone graft substitute versus autogenous bone graft when performed with modified minimally invasive surgical…
- Trial name
- NCT06048042
- Testing
- Autogenous Demineralized Dentin Graft, Autogenous Bone Graft
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Intrabony Periodontal Defect
Evaluation of Volume Stable Collagen Matrix in the Regenerative Outcome of Periodontal Intrabony Defects
Periodontal intrabony defect is a specific osseous defect with definite morphology. Numerous therapeutic modalities for restoring such defects have been investigated.
- Trial name
- NCT05569473
- Testing
- TEST GROUP: VCMX + OFD, CONTROL GROUP : OFD ONLY
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontal Diseases
Influence of Local Doxycycline on the Outcomes of Periodontal Regeneration
In this double-blinded randomized clinical trial, patients presenting periodontal intrabony defects requiring regenerative surgery and showing BoP will be included.
- Trial name
- NCT05878353
- Testing
- Decontamination of the pocket with local doxycycline, Decontamination of the pocket with mechanical instrumentation
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Periodontitis
Autologous Micrografts From the Palatal Mucosa for Periodontal Regeneration
Some research studies have demonstrated that autologous micrografts made out of different oral tissues may enhance tissue regeneration.
- Trial name
- NCT06105125
- Testing
- Rigenera + bone substitute, Bone substitute alone
- Where
- Italy
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Intrabony Periodontal Defect
Effect of Alendronate With β - TCP Bone Substitute in Surgical Therapy of Periodontal Intra-osseous Defects.
The aim of the present study was to evaluate the bone formation potential of 400µg alendronate delivered in β-TCP in the treatment of periodontal intra-osseous defects.
- Trial name
- NCT02795546
- Testing
- Alendronate sodium, beta-tricalcium phosphate bone substitute
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Periodontitis (Stage 3), Minimally Invasive Surgical Procedures
Bone Substitutes and NIPSA in Intrabony Periodontal Defects: A Randomized Controlled Trial
This multicenter randomized controlled clinical trial aims to compare the clinical, radiographic, microbiological and molecular outcomes of two collagenated xenogeneic bone substitutes (GTO® and GenOs®) used in combination with…
- Conditions
- Periodontitis (Stage 3), Minimally Invasive Surgical Procedures, Bone Substitutes
- Trial name
- NCT07671963
- Testing
- GTO® with NIPSA surgical approach, GenOs® + NIPSA
- Where
- 2 sites in Italy, Serbia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Periodontal Diseases
The Use of Leucocyte Platelet Rich Fibrin (L- PRF) Covered Perforated Guided Tissue Membrane for Treatment of Periodontal Intrabony Defects
This study is the first to investigate the effect of leucocyte platelet rich fibrin (L-PRF) combined with perforated membrane in order to treat infrabony defects and assess their combined effect in clinical attachment level gain…
- Trial name
- NCT04576468
- Testing
- Open flap debridement, perforated membrane, leucocyte - platelet rich fibrin
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University