Clinical trials: Periodontal Inflammation
Periodontitis, Inflammation
Evaluation of Trimethylamine N-oxide (TMAO) Levels in Periodontal Disease
Salivary and serum levels of TMAO and TNF-α can distinguish between individuals with periodontitis and periodontally healthy individuals.
- Conditions
- Periodontitis, Inflammation, Trimethylamine N-oxide (TMAO), TNF-alfa
- Trial name
- TMAO (NCT06906510)
- Testing
- Salivary and Serum TMAO Mesurement, Salivary and Serum TNF-α Mesurement
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Periodontal Diseases, Pregnancy Complications
Oral Health and Adverse Pregnancy Complications
Pregnant women are susceptible to develop periodontitis, but these oral health changes related to pregnancy are often neglected.
- Conditions
- Periodontal Diseases, Pregnancy Complications, Pregnancy Preterm, Gestational Diabetes
- Trial name
- NCT06110143
- Testing
- Periodontal treatment
- Where
- 3 sites in Denmark
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Periodontal Inflammation, Orthodontic Appliance Complication
Effects of Social Media on Oral Hygiene With Orthodontic Patients
The aim of this study was to compare the efficacy of traditional and social media motivation strategies in improving oral hygiene with fixed orthodontic treatment.
- Trial name
- NCT06886984
- Testing
- Social media motivation
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Acne Vulgaris, Gingivitis and Periodontal Diseases
Retinoic Acid Therapy and Regulation of Salivary and Serum IL-1β, IL-8 and MCP-1 Levels
This prospective cohort study analysed the effects of systemic retinoic acid use on periodontal status, salivary flow rate (SFR), and salivary and serum levels of interleukin (IL)-1β, IL-8 and monocyte chemoattractant protein…
- Conditions
- Acne Vulgaris, Gingivitis and Periodontal Diseases, Saliva Collection, Inflammation Biomarkers
- Trial name
- NCT06879795
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medipol University
Periodontal Diseases, Periodontal Inflammation
Therapeutic Application of Coconut Oil in Oral Health
The scientific literature has verified that coconut oil has properties that open perspectives for its application in order to maintain oral health and, in particular, for the treatment of different oral pathologies.
- Conditions
- Periodontal Diseases, Periodontal Inflammation, Periodontal Attachment Loss, Periodontitis
- Trial name
- NCT06049589
- Testing
- Coconut Oil, Chlorhexidine mouthwash, Water mouthwash
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundacion Clinica Pardinas
Peri-Implantation Loss, Periodontal Bone Loss
The Rehabilitation of Atrophic Jaws Using Short Implants With Different Surface Characteristics
The aim of the research is to evaluate the clinical outcome of short dental implants, characterized by a new macro-structural design and inserted in the upper or lower jaw in patients with reduced bone volume.
- Conditions
- Peri-Implantation Loss, Periodontal Bone Loss, Periimplantitis, Gingival Inflammation
- Trial name
- NCT05766878
- Testing
- implants placement
- Where
- 3 sites in Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Periodontal Inflammation, Dental Malocclusion
Periodontal Parameters in Orthodontic Patients With Stainless Steel and Ceramic Brackets.
The aim of this study is to assess if there are significant differences in periodontal conditions between patients undergoing fixed orthodontic treatment with stainless steel or ceramic brackets.
- Trial name
- NCT05144555
- Testing
- Fixed orthodontic treatment with stainless steel brackets, Fixed orthodontic treatment with ceramic brackets
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Periodontitis, Periodontal Diseases
Vitamin D Supplementation Prior to Non-surgical Periodontal Therapy
The purpose of this study is to test the feasibility i. e. to examine all aspects necessary for the implementation of a future randomized clinical trial (RCT) that aims to determine whether non-surgical periodontal treatment can…
- Conditions
- Periodontitis, Periodontal Diseases, Periodontal Inflammation, Inflammation
- Trial name
- NCT05398770
- Testing
- Vitamin D supplementation (30 µg/d)
- Where
- Norway
- Volunteers
- 26 people
- Sponsor
- University of Tromso
Periodontal Diseases, Periodontal Pocket
Comparison of Gingival Flap Procedure Using Conventional Surgical Loupes vs. Videoscope for Visualization
This study is being performed to compare different methods of visualization during routine gum surgery. The gum surgery is standard of care.
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontitis, Periodontal Inflammation
- Trial name
- NCT05932017
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Periodontal Diseases, Inflammation
Annexin Levels of Periodontal Inflammatory Regulation
ANXA1, a member of the annexin family, plays a role in the resolution of inflammation and the regulation of anti-inflammatory responses, while ANXA2 is involved in the initiation of the inflammatory responses.
- Trial name
- NCT06554756
- Testing
- Saliva, serum and GCF sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medipol University
Post-Surgical Complication, Periodontal Inflammation
Analysis of Early Healing of Sutures in Periodontal Surgery
The main objective is to analyze post-surgical periodontal healing after conventional periodontal surgery where an absorbable suture coated with clorhexidine (Novosyn Clorhexidine) versus conventional sutures without…
- Conditions
- Post-Surgical Complication, Periodontal Inflammation, Surgical Site Infection
- Trial name
- Sutures (NCT06201377)
- Testing
- Periodontal Access Surgery+ Suture with chlorhexidine, Periodontal Access Surgery+ Suture without chlorhexidine
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ana María García de la Fuente
Periodontal Diseases, Periodontal Pocket
Thyme Honey Mouthwash in Management of Periodontitis in Renal Patients
There is a known correlation between oral health and systemic disease. Particularly significant evidences associate periodontal bacteria and tooth loss to systemic disorders and specifically to cardiovascular disease, such as…
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontal Attachment Loss, Periodontal Inflammation
- Trial name
- NCT06129097
- Testing
- Thyme honey mouthwash
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- British University In Egypt
Periodontal Inflammation
The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy in Different Age Groups
the summary is to evaluate The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy on Inducible Nitrous Oxide Synthase Salivary Levels in Different Age Groups of Chronic Periodontitis Patients
- Trial name
- NCT06140394
- Testing
- diode laser, non surgical scaling
- Where
- 2 sites in Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Pocket, Periodontal, Periodontal Inflammation
Diode Laser Photo Activation for Pocket Reduction Decontamination A Clinical Study
Routine non surgical periodontal thearpy often fails to achieve complete elimination of pathogenic microorganism. This could be attiributable to deep periodontal pockets, root concavities, furcation involvement etc.
- Conditions
- Pocket, Periodontal, Periodontal Inflammation, Periodontal Attachment Loss, Periodontitis
- Trial name
- NCT06404190
- Testing
- Diode laser and 3% hydrogen peroxide
- Where
- India
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Periodontal Diseases, Periodontal Inflammation
Minimally Non Surgical Periodontal Therapy Compared to Traditional Approach
This study aims to evaluate the clinical results of non-surgical periodontal therapy performed with micro-instruments compared to traditional approach (standard curettes) after 6 months of follow-up.
- Trial name
- NCT05060601
- Testing
- Gracey micro-curettes, Standard Gracey curettes
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federico II University
Periodontal Diseases, Periodontal Inflammation
Electroacupuncture as an Adjunct to Non-Surgical Periodontal Therapy
The aim of this randomized, single-masked, controlled clinical trial study was to determine if the administration of electro acupuncture improves the outcomes obtained in combination with non-surgical periodontal therapy.
- Conditions
- Periodontal Diseases, Periodontal Inflammation, Periodontitis, Acupuncture
- Trial name
- NCT06247007
- Testing
- Electroacupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Didem OZKAL EMINOGLU
Periodontal Diseases, Periodontal Pocket
Clinical Efficacy of Saffron Mouth Rinse in Periodontitis Patients With Renal Disease
The commensal oral bacteria are responsible for the initiation and propagation of the disease through the process of dysbiosis, or microbial imbalance.
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontal Inflammation
- Trial name
- NCT06235021
- Testing
- Saffron, chlorhexidine mouthwash
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- British University In Egypt
Periodontitis, Periodontal Inflammation
DNI Values After Periodontal Treatment
The study included 70 systemically healthy individuals, as a test group of 35 patients with Stage 3, Grade A periodontitis and a control group of 35 individuals with no periodontal disease.
- Conditions
- Periodontitis, Periodontal Inflammation, Inflammatory Response
- Trial name
- NCT05666622
- Testing
- Only routine non-surgical periodontal treatment was applied to the patients.
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Periodontal Diseases
Periodontal Status and Endothelial Dysfunction in Patients With Polycystic Ovary Syndrome
Emerging research indicates a link between polycystic ovary syndrome (PCOS) and periodontal diseases, revealing the intricate relationship between oral health and systemic conditions.
- Trial name
- NCT06184412
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Periodontal Inflammation, Crown Lengthening
Effect of Emdogain® on Soft Tissue Wound Healing
The goal of this randomized, controlled, single-center study is to compare the effects of Emdogain®, a regenerative biomaterial, on post-operative pain, wound healing and inflammation of treated sites after surgical crown…
- Trial name
- NCT06179277
- Testing
- PrefGel® + Emdogain®, PrefGel®
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Amir Azarpazhooh