Clinical trials: Periodontal Attachment Loss
Periodontal Attachment Loss
ESWT on Human Gingival Fibroblasts
The idea of treating different deformities or diseases in the maxillofacial region with Extracorporeal Shockwave Therapy (ESWT) has recently become popular.
- Trial name
- ESWT (NCT05766293)
- Testing
- extracorporeal shockwave device, Fibroblast cell lines not subjected to shockwaves from extracorporeal shockwave device
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Dr Prabhuji MLV
Periodontal Diseases, Diabetes Mellitus, Type 2
Antimicrobial Photodynamic Therapy in Patients With Periodontal Disease and Type 2 Diabetes Mellitus
Objectives: This study aimed to determine the effect of concomitant antimicrobial photodynamic therapy (aPTD) on periodontal disease and glycaemic control in patients with type 2 diabetes mellitus (T2DM).
- Conditions
- Periodontal Diseases, Diabetes Mellitus, Type 2, Periodontitis, Periodontal Pocket
- Trial name
- NCT05816941
- Testing
- Conventional Periodontal Treatment (Complete Oral Disinfection), Adjunctive Photodynamic Therapy
- Volunteers
- 24 people
- Sponsor
- University of Ljubljana
Periodontitis, Type 2 Diabetes Mellitus
Diagnostic Biomarkers Related to Periodontal Disease Activity in Diabetic
The purpose of the study was to monitor the activity of periodontal disease and suggest potential biomarkers related to active periodontal disease in patients with chronic periodontitis (PD) associated or not with type 2 diabetes…
- Trial name
- NCT02220751
- Testing
- non-surgical periodontal therapy + systemic doxycycline, Non-surgical periodontal therapy
- Where
- Brazil
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Periodontitis, Periodontal Pocket
Modified Widman Flap vs Fibre Retention Osseous Resective Surgery
The treatment of periodontitis should be carried out in an incremental manner, first by achieving adequate patient's oral hygiene practices and risk factor control during the first step of therapy and then, during the second step…
- Conditions
- Periodontitis, Periodontal Pocket, Periodontal Attachment Loss
- Trial name
- NCT06123000
- Testing
- Modified Widman Flap (MWF), Fiber Retention Osseous Resective Surgery (FibReORS)
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University of Florence
Periodontal Diseases, Periodontal Attachment Loss
Low-level Laser Therapy as an Adjunct to Non-surgical Periodontal Treatment
The present study aimed to investigate the effects of low-level laser therapy (LLLT) as an adjunct to non-surgical periodontal treatment (NSPT) on the plasminogen-activating system in Stage 3-4, Grade C periodontitis patients.
- Conditions
- Periodontal Diseases, Periodontal Attachment Loss, Periodontal Disease, AVDC Stage 3, Periodontal Inflammation
- Trial name
- NCT05233501
- Testing
- low level laser therapy, non-surgical periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Periodontitis, Gingivitis and Periodontal Diseases
Salivary Free Amino Acid Profiles in Periodontitis: Associations With Clinical Parameters and Dynamic Responses to Non Surgical Therapy
# Brief Summary (Word count: 198) This combined observational and interventional study investigates salivary amino acid profiles and their connections to periodontal conditions, as well as how these substances change after…
- Conditions
- Periodontitis, Gingivitis and Periodontal Diseases, Periodontal Debridement, Periodontal Attachment Loss
- Trial name
- FAA-CP-SRP (NCT07669233)
- Testing
- Non-surgical periodontal therapy
- Where
- China
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Zhang, Yuwei
Periodontal Attachment Loss, Periodontal Bone Loss
Platelet-Rich Fibrin and Anorganic Bovine Bone vs Collagen Membrane and Anorganic Bovine Bone in Intrabony Defects
The primary outcome of periodontal reconstructive therapy is to regenerate all tissues of the periodontium including a functional periodontal ligament, alveolar bone and cementum.
- Conditions
- Periodontal Attachment Loss, Periodontal Bone Loss, Periodontal Diseases
- Trial name
- NCT03715374
- Testing
- Periodontal Surgery with PRF+ABB, Periodontal Surgery with Collagen Membrane +ABB
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Obstructive Sleep Apnea of Adult, Periodontal Diseases
Periodontal Disease in Patients With Obstructive Sleep Apnea
Investigators hypothesize that in patients with obstructive sleep apnea (OSA) the severity of periodontal disease is significantly higher compared to patients without OSA in every aspect, including PI, PD, CAL and BOP.
- Conditions
- Obstructive Sleep Apnea of Adult, Periodontal Diseases, Periodontal Pocket, Periodontal Attachment Loss
- Trial name
- NCT04581798
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Periodontal Diseases, Periodontal Pocket
Thyme Honey Mouthwash in Management of Periodontitis in Renal Patients
There is a known correlation between oral health and systemic disease. Particularly significant evidences associate periodontal bacteria and tooth loss to systemic disorders and specifically to cardiovascular disease, such as…
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontal Attachment Loss, Periodontal Inflammation
- Trial name
- NCT06129097
- Testing
- Thyme honey mouthwash
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- British University In Egypt
Periodontitis
Adjunctive Antimicrobial Therapy of Periodontitis: Long-Term Effects on Disease Progression and Oral Microbiological Colonization
The purpose of this study is to determine the size of the benefit of an adjunctive empiric antibiotic therapy compared to standard mechanical debridement and oral hygiene instructions in a representative sample of German…
- Trial name
- ABPARO-Studie (NCT00707369)
- Testing
- Amoxicillin and Metronidazole
- Where
- 8 sites in Germany
- Volunteers
- 540 people
- Sponsor
- University Hospital Muenster
Alveolar Bone Loss, Periodontal Attachment Loss
Bone Height and Extractions Study
A coronectomy is often chosen over complete extraction of a lower third molar when the tooth appears to be in close proximity to the inferior dental (ID) canal, as assessed on a plain radiograph or a cone beam computer tomograph…
- Conditions
- Alveolar Bone Loss, Periodontal Attachment Loss, Periodontal Pocket
- Trial name
- NCT03909568
- Testing
- Third molar surgery
- Volunteers
- 50 people
- Sponsor
- King's College London
Periodontal Diseases, Periodontal Inflammation
Therapeutic Application of Coconut Oil in Oral Health
The scientific literature has verified that coconut oil has properties that open perspectives for its application in order to maintain oral health and, in particular, for the treatment of different oral pathologies.
- Conditions
- Periodontal Diseases, Periodontal Inflammation, Periodontal Attachment Loss, Periodontitis
- Trial name
- NCT06049589
- Testing
- Coconut Oil, Chlorhexidine mouthwash, Water mouthwash
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundacion Clinica Pardinas
Periodontal Diseases, Chronic Periodontitis
Photodynamic Therapy During Supportive Periodontal Therapy
27 subjects on SPT, each with at least two residual pockets ≥5mm, were recruited for this randomised, split-mouth controlled trial, providing a total of 72 sites.
- Conditions
- Periodontal Diseases, Chronic Periodontitis, Periodontal Attachment Loss
- Trial name
- NCT02666573
- Testing
- Fotosan 630, CMS Dental, Copenhagen, Denmark, Scaling and root planing
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Periodontitis, Alveolar Bone Loss
Phase 3 Clinical Trial of Periodontal Tissue Regeneration Using Fibroblast Growth Factor-2(Trafermin)
This study aims to verify the effectiveness of Trafermin (recombinant human basic fibroblast growth factor) in stimulating regeneration of periodontal tissue lost by periodontitis and to evaluate the safety of such stimulation.
- Conditions
- Periodontitis, Alveolar Bone Loss, Periodontal Attachment Loss
- Trial name
- NCT00734708
- Testing
- Trafermin (genetical recombination)
- Where
- 21 sites in Japan
- Volunteers
- 328 people
- Sponsor
- Kaken Pharmaceutical
Attachment Loss, Periodontal
Relationship Between Contact Point to Attachment Level and Presence of Interdental Papilla
Thorough search of literature revealed no study has correlated the presence/absence of papilla to the contact point to attachment level distance.
- Trial name
- NCT06184607
- Testing
- Distance from contact point to attachment level
- Where
- India
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontal Attachment Loss
Non - Incised Papilla Versus Single Flap Technique In The Reconstruction Of Intrabony Defect
The present study will aim to assess the effectiveness of the non-Incised Papilla surgical approach NIPSA used for the surgical debridement of deep intraosseous defects compared to the single-flap approach SFA.
- Trial name
- NCT06003322
- Testing
- non - Incised Papilla surgical approach NIPSA for intrabony defect, single-flap approach SFA
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Periodontal Diseases, Periodontal Bone Loss
Entire Papilla Preservation Technique in the Treatment of Periodontal IntraBony Defects: a 1-year Follow-up Study
The aim of this study was to investigate the radiographic and clinical outcomes associated with the whole papilla preservation technique in the treatment of isolated intraosseous defects in patients with stage III periodontitis.
- Trial name
- EPP (NCT06744348)
- Testing
- ENTİRE PAPİLLA PRESERVATİON
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Periodontitis, Periodontal Diseases
Non-Incised Papillae Surgical Approach (NIPSA) With and Without Graft
This study compared the clinical outcomes of the non-incised papila surgical approach (NIPSA) alone and with grafting biomaterial.
- Conditions
- Periodontitis, Periodontal Diseases, Periodontal Pocket, Periodontal Attachment Loss
- Trial name
- NIPSAGRAFT (NCT04712630)
- Testing
- Non-incised papila surgical approach without grafting biomaterial, Non-incised papila surgical approach with grafting biomaterial
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Universidad de Murcia
Periodontal Disease, Mobility, Tooth
Method for Measuring Dental Mobility and Displacement Force
This study aims to investigate the use of a new method for measuring tooth mobility, which includes control of force (gf) and labial/lingual/palatal displacement (mm) of upper and lower incisors with tooth mobility.
- Trial name
- NCT06600867
- Testing
- Tooth mobility assessment
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Campinas, Brazil
Periodontitis, Attachment Loss, Periodontal
The Use of a Non-Incised Minimally Invasive Flap Procedure in Conjunction With Emdogain® MI Compared to Traditional SRCP
This study is designed to evaluate the use of Emdogain® MI in a procedure where a significant portion of the lining of the sulcus is removed by curettage (similar to the traditional clinical procedure described as "gingival…
- Trial name
- NCT05964699
- Testing
- Minimally invasive periodontal therapy with use of Emdogain, Minimally invasive periodontal therapy without the use of Emdogain
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Texas A&M University