Clinical trials: Perinatal Asphyxia
Perinatal Depression, Perinatal Anxiety
Effectiveness and Implementation of a Personalized mHealth Intervention for the Universal Prevention of Maternal Perinatal Mental Disorders
This study is part of the ERC-funded e-Perinatal project and represents a large-scale hybrid type 1 effectiveness-implementation cluster randomized controlled trial.
- Trial name
- ePerinatal-RCT (NCT07613008)
- Testing
- The e-Perinatal intervention is a personalized mobile health (mHealth) program, Standard routine maternal care
- Where
- Spain
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Seville
Anxiety Disorder (Panic Disorder or GAD), Anxiety Symptoms
Anxiety is One of the Most Frequent Disorders During the Perinatal Stage Which is Associated with Adverse Health Effects for Women and Their Babies. This Study Will Be to Evaluate the Effectiveness of a Telematic Cognitive-behavioral Preventive Intervention to Manage Anxiety During Pregnancy.
Anxiety is one of the most frequent disorders during the perinatal stage which is associated with adverse health effects for women and their babies. In spite of this, preventive interventions during this stage are scarce.
- Trial name
- NCT06609291
- Testing
- Telematic Prenatal Psychological Intervention for Preventing Anxious Symptomatology
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Depression During Pregnancy, Depression, Postpartum
IMAGINE: Pilot Trial of a Digital Group Intervention to Prevent Perinatal Depression
The goal of this clinical trial is to evaluate if a digital group intervention (named IMAGINE) can prevent depression in perinatal populations.
- Trial name
- NCT06746337
- Testing
- IMAGINE
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Obstetric and Perinatal Complications, Postpartum Hemorrhage
A Skills and Drills Intervention for Emergency Obstetrics and Neonatal Care at First Referral Units of North Karnataka
To evaluate the effectiveness of a First Referral Unit (FRU) Emergency Obstetric and Newborn Care (EmONC) skills and drills intervention, to estimate the appropriateness and effectiveness of referrals in intervention arm compared…
- Conditions
- Obstetric and Perinatal Complications, Postpartum Hemorrhage, Preeclampsia/Eclampsia, Obstructed/Prolonged Labor
- Trial name
- NCT01865656
- Testing
- Skills training, Emergency obstetric drills, Revised Case Sheets
- Volunteers
- 15,018 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Perinatal Depression, Perinatal Anxiety
Testing "Doula Link", a Multi-Component Intervention to Improve Perinatal Mental Health
Doulas are trained individuals who offer informational, emotional, and physical support to their pregnant, birthing, and postpartum clients.
- Trial name
- Doula Link (NCT07217561)
- Testing
- Doula Link
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Perinatal Depression, COVID19
Global Mental Health of Urban Mothers
Mental health disorders are common during pregnancy and the postnatal period, and can have serious adverse effects on the well-being of woman and child.
- Conditions
- Perinatal Depression, COVID19, Anxiety, PTSD
- Trial name
- MUM (NCT04363177)
- Testing
- Web-based psychosocial peer-to-peer support
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Pregnancy, Postpartum Period
Effect of Exercise on Perinatal Depression
Fifteen percent of women experience depression during pregnancy or postpartum (i.e., perinatal depression). Furthermore, 38% of low income women experience postpartum depression.
- Conditions
- Pregnancy, Postpartum Period, Depression
- Trial name
- NCT02791932
- Testing
- Exercise
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Perinatal Depression, Parents
Effect of 'Parentbot - a Digital Healthcare Assistant (PDA)' in Improving Parenting Outcomes During the Perinatal Period
The Parentbot - a Digital healthcare Assistant (PDA) is a mobile application-based psychosocial parenting intervention with integrated chatbot features, intended for couples to use during the perinatal period.
- Conditions
- Perinatal Depression, Parents, Self Efficacy, Anxiety
- Trial name
- PDA (NCT05463926)
- Testing
- PDA mobile application
- Where
- Singapore
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Perinatal Depression, Chronic Pain
CSF/Serum Biomarkers in Predicting PND/Persistent Pain After Cesarean
The aim is to investigate if inflammatory biomarkers in the blood and cerebrospinal fluid (CSF) are associated with the development of perinatal depression and/or persistent pain after cesarean delivery.
- Trial name
- NCT04271072
- Testing
- No intervention
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Duke University
Perinatal Depression
Accelerating Implementation of Mindful Mood Balance for Moms
The Mindful Mood Balance for Moms (MMBFM) study examines whether using an internet program called Mindful Mood Balance for Moms to deliver Mindfulness Based Cognitive Therapy (MBCT) over an 8-week time period, is effective for…
- Trial name
- MMB4Moms (NCT04846504)
- Testing
- MMBFM program with clinician coach support, MMBFM program with peer coach support, Patient facing strategy intervention arm
- Where
- 4 sites in United States
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Perinatal Anxiety, Anxiety Sensitivity
Reaching Calm: A Digital Intervention to Prevent Perinatal Anxiety Disorders
The goal of this clinical trial is to find out if a digital program called Reaching Calm can help prevent anxiety in women who are pregnant.
- Conditions
- Perinatal Anxiety, Anxiety Sensitivity, Perinatal Depression
- Trial name
- NCT07458698
- Testing
- Digital mental health intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Massachusetts, Worcester
Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy
Nephroprotection Following Perinatal Asphyxia: Randomized Controlled Trial
The aim of this study is to determine the value of Pentoxifylline for nephroprotection in these neonates with perinatal asphyxia, using cystatin C, regional oxygenation measured near infrared spectroscopy and renal Doppler…
- Conditions
- Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy, Pentoxifylline Adverse Reaction
- Trial name
- NCT07088328
- Testing
- Pentoxifylline
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Perinatal Depression, Postpartum Depression
MomMoodBooster VA Program
The MomMoodBooster intervention is an empirically validated treatment for postpartum depression symptoms. The intervention was created by Brian Danaher and Milagra Tyler, who have continued to update the intervention technology…
- Trial name
- Perinatal MMB (NCT05196152)
- Testing
- MomMoodBooster, Phone Coaching
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Iowa
Pregnancy Related, Stress, Psychological
The Stony Brook University Calm-Mom Study
The present trial will evaluate the feasibility, acceptability and preliminary efficacy of 2 different internet-delivered programs for prenatal maternal stress.
- Conditions
- Pregnancy Related, Stress, Psychological, Anxiety, Perinatal Depression
- Trial name
- NCT04018625
- Testing
- SMART Mom, Mama Support
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Stony Brook University
Perinatal Depression
Perinatal Mental Health Screening and Early Community Intervention Using Digital Clinical Pathways (MATTER Project)
The MATTER project is a digital, community-based perinatal mental health screening and early intervention program implemented in primary care and hospital settings in the Alentejo region, Portugal.
- Trial name
- MATTER (NCT07659977)
- Where
- Portugal
- Volunteers
- 1,500 people
- Sponsor
- Universidade Nova de Lisboa
Sepsis, Pneumonia
Improved Accessibility of EmONC Services for Maternal and Newborn Health: a Community Based Project
The purpose of this study is to determine whether an integrated EmONC package (community mobilization, training of community-based health care providers and a maternal and neonatal health pack) reduce perinatal and neonatal…
- Conditions
- Sepsis, Pneumonia, Omphalitis, Birth Asphyxia
- Trial name
- EmONC (NCT01751945)
- Testing
- EmONC package
- Where
- Pakistan
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Postpartum Depression, Perinatal Depression
Maternal Mental Health Access - MaMa
This hybrid effectiveness-implementation project will allow the team to evaluate and refine implementation in preparation for future multisite trials to ultimately move the Evidence-Based Intervention (EBI) to scale among diverse…
- Trial name
- MaMa (NCT06049433)
- Testing
- Maternal Mental Health Access for Postpartum Depression- Prevention and UPLIFT- intervention, On-Demand + Discussion board (DB), Arm 2
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Utah
Post Partum Depression, Perinatal Depression
mHealth Mindfulness Intervention for Pregnant Black and Latina Women at Risk of Postpartum Depression
Postpartum depression (PPD) is associated with significant health consequences for mothers and children, and the current COVID-19 pandemic has had a major impact on the mental health of particularly vulnerable populations…
- Trial name
- NCT05186272
- Testing
- Stress reduction program 'A', Stress reduction program 'B'
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Kaiser Permanente
Perinatal Depression
A Smartphone-Assisted Brief Behavioral Intervention for Pregnant Women With Depression
Investigators developed Motherly 1.0, a smartphone app designed to treat and promote maternal mental health. A 2-arm parallel-randomized controlled clinical trial (RCT) will be conducted to test the efficacy of Motherly in…
- Trial name
- NCT04495166
- Testing
- Motherly 1.0, Brief Psychotherapy, Educational app
- Where
- Brazil
- Volunteers
- 81 people
- Sponsor
- University of Sao Paulo
Postpartum Blues, Birth Depression
The Effect of Music Played to Newborn Mothers on Postpartum Blues
The prospective and two-arm randomized controlled study was conducted on n = 82 (41 = control, 41 = music group) mothers who gave birth at term at Trakya University Health Research and Application Center Maternity Service between…
- Conditions
- Postpartum Blues, Birth Depression, Mothers
- Trial name
- NCT06252155
- Testing
- Music
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Trakya University