Clinical trials: Perinatal
Perinatal Disorders of Growth and Development
Effect of Intensive Dietary Intervention in Children With Birth Weight Between 1500 and 2000 g
There are few scientific reports on preterm infants with birth weights between 1500 and 2000g. Adequate and properly balanced supply of nutrients believed to better growth and cognitive development in this patient group, and…
- Trial name
- CAKE (NCT02833818)
- Testing
- CAKE-intervention, CAKE-control
- Volunteers
- 200 people
- Sponsor
- Elin Wahl Blakstad
Substance-Related Disorders
Growing Together: Women in Opioid Treatment and Their Infants
This study evaluates the effectiveness of the home-based therapeutic parenting intervention BRIGHT with pregnant women and postpartum mothers with opioid use disorders (OUDs) and their infants.
- Trial name
- NCT03866694
- Testing
- BRIGHT, STAR/TAU+
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Boston University Charles River Campus
Thromboembolism, Venous Thromboembolism
Retrospective Study of Patients Who Were Treated With Fondaparinux Pre-, Peri- and/or Postpartum for Prophylaxis or Treatment of Venous Thromboembolism
The objective of this retrospective study is to gather information about how fondaparinux is used pre-, peri- and/or postpartum for both the prophylaxis and treatment of venous thromboembolism (VTE) in order to fill an…
- Trial name
- FondaPPP (NCT01004939)
- Testing
- fondaparinux
- Where
- 7 sites in Germany
- Volunteers
- 120 people
- Sponsor
- GlaxoSmithKline
Intimate Partner Violence
Domestic Violence Enhanced Perinatal Care Program in China
The proposed project addresses intimate partner violence (IPV) against pregnant women, which is a serious social and health issue.
- Trial name
- NCT05388565
- Testing
- Domestic Violence Enhanced Perinatal Care Program, Standard of Care
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Preeclampsia
Randomizated Open-label Control Trial to Evaluate if the Incorporation of sFlt1/PlGF Ratio in the Diagnosis and Classification of PE Improves Maternal and Perinatal Outcomes in Women With the Suspicion of the Disease
Preeclampsia is a leading cause of maternal and neonatal morbidity and mortality worldwide. The morbidity and mortality of this condition arises from two main causes: 1) the lack of specific and sensible methods for its diagnosis…
- Trial name
- EuroPE (NCT03231657)
- Testing
- Placental biomarkers
- Where
- Spain
- Volunteers
- 2,536 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Pregnancy
Development of a Lifestyle Physical Activity Intervention to Reduce Risk for Perinatal Cannabis Use - RCT
The overall goal of this pilot study is to develop and preliminarily evaluate an LPA intervention designed to reduce cannabis use during pregnancy.
- Trial name
- NCT06239701
- Testing
- LPA+Fitbit Intervention, Fitbit Only
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Medical Education
Comparison of Learning in Traditional Versus "Flipped" Classrooms
This is an educational research study to compare knowledge retention of neonatal-perinatal medicine (NPM) fellowship trainees instructed on a subsection of the American Board of Pediatrics (ABP) NPM Content Outline using…
- Trial name
- NCT03758391
- Testing
- Flipped Classroom education
- Where
- United States
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Pregnancy Related, Stress, Psychological
The Stony Brook University Calm-Mom Study
The present trial will evaluate the feasibility, acceptability and preliminary efficacy of 2 different internet-delivered programs for prenatal maternal stress.
- Conditions
- Pregnancy Related, Stress, Psychological, Anxiety, Perinatal Depression
- Trial name
- NCT04018625
- Testing
- SMART Mom, Mama Support
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Stony Brook University
Preeclampsia (PE)
Impact of First-trimester Preeclampsia Screening on Perinatal and Maternal Morbidity (RANSPRE)
The purpose of this study is to determine whether first-trimester screening for preeclampsia based on the FMF algorithm (a combination of maternal clinical, sonographic and biochemical parameters), improves maternal or perinatal…
- Trial name
- RANSPRE (NCT05521776)
- Testing
- First-trimester preeclampsia screening (FMF triple test)
- Where
- 22 sites in France
- Volunteers
- 14,500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depressive; Episode, Major, Depression, Postpartum
Diagnostic Accuracy of the Stepped Screening Protocol and Its Screening Tools in the Perinatal Period.
It is known that 1 in 5 women experience psychological difficulties during their pregnancy or in the first year after giving birth.
- Conditions
- Depressive; Episode, Major, Depression, Postpartum, Anxiety Disorders, Obsessive-Compulsive Disorder
- Trial name
- DAS (NCT05961306)
- Testing
- SCID 5
- Where
- 2 sites in Belgium
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Postpartum Depression
IPT-G for Mums With Postpartum Depression
Postpartum depression is a very common and costly illness with numerous, long-term deleterious effects for women, their offspring and families; yet most women are not treated.
- Trial name
- OPTIMUM (NCT04580901)
- Testing
- Group Interpersonal Psychotherapy
- Where
- Canada
- Volunteers
- 95 people
- Sponsor
- McMaster University
Perinatal Anxiety, Perinatal Depression
Improving Perinatal Mental Health Through a Collaborative, Community Health Worker and Social Worker Intervention
The goal of this clinical trial is to learn if an intervention can improve mental health outcomes among pregnant and postpartum Latinas.
- Trial name
- NCT07880457
- Testing
- Patient Navigation (PN), Problem Solving Therapy (PST)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- American University
Perinatal Outcomes
Can Safety Planning Improve Perinatal Outcomes Among Pregnant Women Exposed to Intimate Partner Violence?
OBJECTIVE: To investigate if, among women exposed to physical violence during pregnancy, does a targeted intervention consisting of safety planning and referral to community advocacy services decrease rates of adverse perinatal…
- Trial name
- NCT00831831
- Testing
- Safety planning
- Where
- Canada
- Sponsor
- University of British Columbia
Perinatal Depression, HIV-1-infection
A Pilot Trial of Perinatal Depression Treatment in HIV Infected Women
This pilot study will evaluate, through quantitative and qualitative methods, whether different treatments for postpartum depression are feasible and acceptable in postpartum HIV infected women on antiretrovirals (ART).
- Trial name
- NCT04094870
- Testing
- Sertraline, Interpersonal therapy
- Where
- 2 sites in Zambia
- Volunteers
- 80 people
- Sponsor
- University of North Carolina, Chapel Hill
Adrenocortical Carcinoma, Localized Resectable Neuroblastoma
Natural History Study of Infants With Adrenal Masses Found on Prenatal and/or Neonatal Imaging
This natural history study is collecting health information about infants with adrenal masses found on prenatal and/or neonatal imaging.
- Conditions
- Adrenocortical Carcinoma, Localized Resectable Neuroblastoma, Precancerous Condition
- Trial name
- NCT00445718
- Testing
- computed tomography, 3-Tesla magnetic resonance imaging, Abdominal Sonogram
- Where
- 45 sites in United States, Australia and 1 more
- Volunteers
- 97 people
- Sponsor
- Children's Oncology Group
Cephalohematoma
Needle Aspiration for Large Cephalohematoma
The cephalohematoma is a common pathology of newborns. Observation is the primary treatment for the most of small uncomplicated cephalohematoma.
- Trial name
- NCT03875456
- Where
- France
- Volunteers
- 67 people
- Sponsor
- University Hospital, Montpellier
Parents, COVID-19 Pandemic
Becoming a Parent During the COVID-19 Pandemic in Austria and Germany
This is an online survey in Austria and Germany directed at parents with children born since the start of the first lockdown of the COVID-19 pandemic (birthdate beginning with 16.03.2020).
- Trial name
- NCT05487105
- Where
- Austria
- Volunteers
- 2,226 people, healthy volunteers welcome
- Sponsor
- University of Salzburg
Depression
Perinatal Depression Treatment and Child Development
The purpose of this study is to examine whether the successful perinatal depression intervention among mothers (Thinking Healthy Programme, THP) has led to improved developmental outcomes in the children 6 years later.
- Trial name
- NCT01826903
- Where
- Pakistan
- Volunteers
- 964 people
- Sponsor
- Duke University
Stroke With Hemiparesis, Perinatal Stroke
National Egyptian Network Pediatric Stroke and Hemiplegia Registry
Our aim is to establish multi-center national Egyptian database of information about cerebrovascular stroke and hemiplegia in infants and children from 0 to 18 years of age.
- Conditions
- Stroke With Hemiparesis, Perinatal Stroke, Focal Neurologic Deficits
- Trial name
- NCT02129491
- Where
- Egypt
- Volunteers
- 1,000 people
- Sponsor
- Ain Shams University
Perinatal, Cannabis Use
Feasibility and Acceptability Trial to Reduce Tobacco and Cannabis Use During Pregnancy and Postpartum
Using both tobacco and cannabis during pregnancy is more common in minoritized groups and can make quitting smoking in pregnancy and remaining smoke free postpartum difficult.
- Conditions
- Perinatal, Cannabis Use, Tobacco Use, Smoking Cessation
- Trial name
- PICTURe (NCT07489443)
- Testing
- Perinatal smoking cessation treatment and maintenance sessions
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Pittsburgh