Clinical trials: Periimplantitis
Peri-implantitis
Implant Survival After Surgical Treatment of Peri-implantitis of Infra-bony Defects
To report the 10 years outcomes of a reconstructive surgical protocol for peri-implantitis defects with different morphologies, by means of deproteinized bovine bone mineral with 10% collagen (DBBMC).
- Trial name
- Bony defects (NCT07809334)
- Testing
- Reconstructive therapy
- Where
- Italy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Peri-Implantitis
In Vivo Biofilm Accumulation on Implants With 3 Different Surfaces
A frequent sequela of peri-implantitis itself, but also of its surgery, is the exposure of the implant surface to the oral environment.
- Trial name
- NCT06049121
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Malmö University
Peri-Implantitis
Dental Hygiene and Peri-Implant Tissues Homeostasis Ancillary Study
Peri-implantitis is an inflammatory disease that leads to loss of jawbone around dental implants. Recent discoveries have identified increased release of Titanium (Ti) particles around implants as being associated to…
- Trial name
- NCT03917264
- Testing
- Peri-implantitis debridement, Dental hygiene procedures
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Washington
Periodontal Diseases, Periimplant Diseases
Markers of Bone Destruction and Oxidative Stress in Peri-implantitis
The aim of this study is to evaluate and compare the levels of bone resorption (RANKL, OPG) and oxidative stress (Nitrotyrosine, NQO1) markers, along with pro-inflammatory cytokines (IL-1β), in the saliva and peri-implant…
- Trial name
- NCT07397884
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Edentulous Alveolar Ridge, Peri-Implantitis
Soft Tissue Response to Different Restorative Materials Used in Implant Dentistry
The goal of this clinical trial is to learn how different materials used in dental implants affect the surrounding gum tissue in adults who need dental implants.
- Conditions
- Edentulous Alveolar Ridge, Peri-Implantitis, Peri-implant Mucositis, Prosthetic Infection
- Trial name
- NCT06554041
- Testing
- Dental Crown with Titanium-Abutment, Dental Crown with PEEK (Polyetheretherketone)-Abutment, Dental Crown with Zirconia-Abutment
- Where
- Lithuania
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Peri Implant Mucositis, Peri Implant Bone Loss
Local and Systemic Inflammatory Bone Alterations Related to Dental Implant Survival.
Introduction: Dental implants offer a durable, aesthetic, and functional option for tooth replacement. However, they are not immune to failure.
- Conditions
- Peri Implant Mucositis, Peri Implant Bone Loss, Peri Implantitis, Calcium Deficiency
- Trial name
- NCT07766707
- Where
- Spain
- Volunteers
- 192 people
- Sponsor
- University of Barcelona
Periodontitis
Antibiotic Study for Dental Implants
This study is for people at least 21 years old who have signs of problems, like swollen gums and shrinking bones, by dental implants.
- Trial name
- NCT00662532
- Testing
- Minocycline HCl
- Where
- 4 sites in United States
- Volunteers
- 44 people
- Sponsor
- OraPharma
Peri Implantitis
Immediate Versus Delayed Surgical Reconstruction of Peri-implantitis Intra-bony Defects.
The purpose of this study is to test the comparative efficacy of two surgical approaches (immediate versus delayed GBR) for the surgical reconstruction of peri-implantitis intra-bony defects in terms of the clinical…
- Trial name
- NCT07325747
- Testing
- Staged peri-implant debridement and regeneration, Simultaneous peri-implant debridement and regeneration
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Peri-implant Mucositis, Peri-Implantitis
The Effect of Different Dental Implant Surface Characteristics on Immunological and Microbiological Parameters
Objectives: To assess the levels of TNF-α, PGE2, RANKL, RANK, OPG, which are immunological markers of peri-implant disease and F. nucleatum, P. gingivalis, T. denticola, T. forsythia, P. intermedia, S.
- Trial name
- NCT03693196
- Testing
- PICF, Perio-paper®, Subgingival Plaque, Hu-Friedy®, Williams probe, PCPNU-15 Hu-Friedy®
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Peri Implantitis
BonyPid-500TM Bone Graft Substitute Study
This study is designed to assess the safety and effectiveness of BonyPid-500TM implantation for intrabony peri-implantitis defects.
- Trial name
- NCT02531100
- Testing
- BonyPid 500TM implantation concomitantly to SOC treatment, SOC treatment only
- Where
- 2 sites in Israel
- Volunteers
- 27 people
- Sponsor
- PolyPid Ltd.
Peri-implantitis
Reconstruction of Peri-implant Osseous Defects: A Randomized Trial
The purpose of this randomized trial was to compare reconstructive surgery of advanced peri-implant intra-osseous defects with porous titanium granules (PTG/Test) to open flap debridement (OFD/Control) in a non-submerged…
- Trial name
- NCT02406001
- Testing
- Tigran PTG, Surgical intervention
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Tigran Technologies AB
Implant
Effect of Fermented Products and Probiotics on the Condition of the Implant
126 individuals with peri-implant disease and health, aged between 18-70 years, who applied to Bolu University Faculty of Dentistry Periodontology Clinic, participated in the study.The inclusion criteria for patient participation…
- Trial name
- EFFPCFPDH (NCT05921357)
- Testing
- Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Tuğba ŞAHİN
Peri-implantitis
Effect of Enamel Matrix Derivative or Hyaluronic Acid on Non-Surgical Treatment of Peri-Implantitis
The aim of the present randomized controlled clinical study is to compare the clinical, radiographic, and patient-centered efficacy of adjunctive application of either enamel matrix derivative (EMD) or hyaluronic acid (HA) gel in…
- Trial name
- NCT06618560
- Testing
- Enamel Matrix Derivative application, Hyaluronic Acid (HA), Control
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Peri-Implantitis, Peri-implant Mucositis
Comparison of the Accuracy of Different Periodontal Probes for Peri-implant Pocket Registration
Various types of periodontal probes (e.g., metal probes, plastic/bendable probes, electronic periodontal probes) are used for peri-implant pocket depth registration; however, depending on the shape and size of the prosthetic…
- Trial name
- NCT05332327
- Where
- Sweden
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Malmö University
Peri-implantitis
Non-Surgical Treatment of Peri-implantitis with Systemic Azithromycin or Placebo
The primary objective of this study is to evaluate the change in probing depth in patients with peri-implantitis, assessing the influence of systemic antibiotic (azithromycin) adjunctive to non-surgical treatment at 12 months.
- Trial name
- NSTP (NCT06715150)
- Testing
- Azithromcyin
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- University of Santiago de Compostela
Peri-Implantitis
Peri-implantitis in HIV-positive Patients With Different Dental Prosthesis
Dental implants are widely used in human immunodeficiency virus (HIV)-positive patients, but the interaction between immune status and success of implant therapy, especially in such patients, is not clear.
- Trial name
- PERIHIV (NCT04983212)
- Testing
- periodontal control
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- Università Vita-Salute San Raffaele
Peri-Implantitis
Reconstructive Surgical Therapy of Peri-implantitis
Various treatment protocols of peri-implantitis involving surgical therapies with open flap debridement procedures, resective or reconstructive modalities have been documented to achieve variable success.
- Trial name
- NCT04769609
- Testing
- bioresorbable membrane
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Gazi University
Peri-Implantitis, Peri-Implant Health
Comparison of the Effectiveness of Two Different Surgical Therapeutic Protocols of Peri-implantitis
The purpose of the present study is to compare the 1-year clinical, radiographic and microbiological outcomes and patients' satisfaction following surgical treatment of peri-implantitis after applying two different surface…
- Trial name
- NCT05899933
- Testing
- Non-surgical peri-implant therapy, Implantoplasty, Erythritol Air-abrasive device
- Where
- Greece
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Peri-Implantitis
ATR-FTIR and Raman Spectroscopy of Peri-Implant Crevicular Fluid in Peri-Implantitis
Peri-implantitis is an inflammatory condition affecting the tissues surrounding dental implants and may lead to supporting bone loss. Current diagnosis is mainly based on clinical and radiographic findings.
- Trial name
- NCT07864233
- Testing
- ATR-FTIR and Raman Spectroscopic Analysis of Peri-Implant Crevicular Fluid
- Volunteers
- 100 people
- Sponsor
- Necmettin Erbakan University
Dental Implants,Peri-implantitis,Smoking
Effect of Heavy Smoking on Hard and Soft Tissue Parameters Prospective Clinical Trial
The Aim of this study randomized prospective clinical trial is to examine and compare periimplant tissue changes between heavy smokers and non-smokers at 12 months post loading using the alpha Bio Neo standard diameter implants…
- Trial name
- NCT03766022
- Testing
- Neo dental implant Alpha Bio Tec. Ltd.
- Where
- Israel
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus