Clinical trials: Periimplantitis
Periimplantitis, Periodontitis
Evaluation of the Effects of Routine Phase I Periodontal Therapy on Clinical Parameters and Levels of Gremlin-1, CTHRC1, and Tenascin-C in Gingival Crevicular Fluid and Peri-Implant Sulcular Fluid in Individuals With Periodontitis and Peri-Implantitis
The aim of this study is to compare the mechanisms of tissue destruction between natural teeth with periodontitis and implants with peri-implantitis within the same individual, and to evaluate the effects of routine Phase I…
- Trial name
- NCT07797127
- Testing
- Routine Phase I Non-Surgical Periodontal Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Local Anesthesia, Dental Implants
Comparison of Anesthetic Efficacy and Safety Between Inferior Alveolar Nerve Block and the Infiltrative Technique for the Treatment of Peri-implant Diseases in Posterior Mandibular Implants
This triple-blind randomized clinical trial aims to compare the anesthetic efficacy and safety of two local anesthesia techniques for the surgical treatment of peri-implantitis in posterior mandibular implants: inferior alveolar…
- Conditions
- Local Anesthesia, Dental Implants, Periimplantitis
- Trial name
- NCT07590037
- Testing
- Comparison of anesthetic efficacy and safety between nerve block and infiltrative technique for periimplantitis surgical treatment in poosterior mandibular implants
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Periimplantitis
Evaluatıon of TREM-1, MMP-8 and TIMP-1 Levels in Perı-Implant Crevicular Fluıd of Perı-Implanted Indıvıduals
The aim of this study was to evaluate the relationship between Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1), Matrix Metalloproteinases-8 (MMP-8) and Tissue Inhibitors of Metalloproteinases-1 (TIMP-1) levels in…
- Trial name
- NCT07379892
- Testing
- Collection of PICF samples
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Periimplantitis, Periimplant Diseases
Non-surgical Treatment of Peri-implantitis Using Chitosan Brush and Tetracycline Slurry
Aim: The aim of this prospective, randomized, parallel arm, blind clinical trial is to compare the clinical and radiographic outcomes following non-surgical treatment of mild peri-implant defects using Labrida Bioclean with or…
- Trial name
- NCT06695559
- Testing
- Labrida Bioclean, Tetracycline slurry
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Periodontal Diseases, Periodontal Pocket
Occlusal Load Distribution and Periodontal Status
Occlusal forces are unevenly distributed among teeth during mastication, potentially predisposing certain teeth to higher functional loads.
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontitis, Periimplantitis
- Trial name
- Perio-Occlusio (NCT07199062)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Periimplantitis, Microbial Colonization
The Effect of Smoking on Peri-implantitis
the primary aim of this project is to evaluate the microbiological and inflammatory effect of smoking status and smoking severity on periimplantitis lesions.
- Conditions
- Periimplantitis, Microbial Colonization, Cytokines
- Trial name
- NCT06150066
- Testing
- Recruiting samples
- Where
- 2 sites in Switzerland, Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Periimplantitis
Non-surgical Treatment of Periimplantitis - Conventional Hand Instrumentation Versus Air-polishing
The purpose of this study is to evaluate the clinical efficacy of ultrasonic instrumentation versus the use of an erythritol jet in the treatment of peri-implantitis.
- Trial name
- NCT05811390
- Testing
- erythritol jet, Manual instrumentation
- Where
- Portugal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Peri-Implantation Loss, Periodontal Bone Loss
The Rehabilitation of Atrophic Jaws Using Short Implants With Different Surface Characteristics
The aim of the research is to evaluate the clinical outcome of short dental implants, characterized by a new macro-structural design and inserted in the upper or lower jaw in patients with reduced bone volume.
- Conditions
- Peri-Implantation Loss, Periodontal Bone Loss, Periimplantitis, Gingival Inflammation
- Trial name
- NCT05766878
- Testing
- implants placement
- Where
- 3 sites in Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Periimplantitis
The Role of Functional Epigenetic Modifications in Peri-Implantitis
The aim of this pilot, exploratory, single blind clinical trial is to evaluate the epigenetic changes associated with peri-implantitis.
- Trial name
- NCT03753464
- Testing
- Gingival biopsy and blood sample collection
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
Periimplantitis
Comparison of Denture Base Adaptation and Per-iimplant Tissue Health Between CAD and CAM Implant Overdenture
Background: Complete overdenture manufacturing has been greatly developed using computer-aided designing and computer-aided manufacturing (CAD-CAM) technology.
- Trial name
- NCT06166446
- Testing
- subtractive technique, additive technique
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Periimplantitis, Marginal Bone Loss
A Study of the Crestal Bone Loss Around Bone Level Versus Tissue Level Implants in Non-compliant Patients With Healthy or Reduced Periodontium After 5-8 Years in Function
The goal is to evaluate, after 5 to 8 years, the marginal bone loss around tissue-level implants and bone-level implants in patients who have not followed the maintenance program.
- Trial name
- NCT04942808
- Testing
- Periapical radiographs
- Where
- Lebanon
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Periimplantitis
Cross-sectional Examination of the Reliability of Oral Implants
Aim of the multi centrical, cross-sectional study is the registration of the prevalence and incidence of mucositis and periimplantitis.
- Trial name
- PeriX2012 (NCT04690621)
- Where
- Germany
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- German Association of Oral Implantology e. V.
Periimplantitis, Oral Surgery
Impact of Buccal Bone Thickness on Pathological Peri-implant Bone Loss: A 3-year Prospective Cohort Study
Implant placement may trigger bone trauma, which might result in 3-dimensional bone changes. While the process of peri-implant disease is not well understood, implant position within the bony structure might play a role.
- Trial name
- NCT02939222
- Testing
- Implant placement
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Periodontitis, Periimplantitis
PPAR, RXR, and VDR Expressions in Peri-implantitis
ABSTRACT Objective: Periodontitis and peri-implantitis are the irreversible destructive diseases of the periodontal and peri-implant tissues.
- Trial name
- NCT04020146
- Testing
- Gingival biopsies
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Periimplantitis
Implant Healing Abutment and Chlorhexidine
The work hyposesis is based on the application of a chlorhexidine gel against the non-application on the healing abutments in patients who have received a submerged titanium implant to check its effect on healing and prevention…
- Trial name
- CHX-HA (NCT03142828)
- Testing
- Chlorhexidine
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Periimplantitis, Periodontal Disease
Preventive Maintenance Therapy on Peri-implant Diseases
In the field of periodontics, periodontal support therapy has proven to be essential in preventing the incidence or recurrence of periodontal diseases. The protocol is designed according to the risk profile of a patient.
- Trial name
- PIMT (NCT02789306)
- Testing
- Epidemiological study on the incidence of peri-implantitis
- Where
- Spain
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Periimplantitis, Dental Plaque
Antimicrobial Activity of Two Mouthwashes
This is a three arm randomized trial. The aim is to evaluate the antimicrobial activity of chlorhexidine and polyhexamethylene biguanide oral antiseptics on the microorganisms of the oral cavity.
- Conditions
- Periimplantitis, Dental Plaque, Periodontal Diseases, Caries
- Trial name
- NCT02375178
- Testing
- chlorhexidine, Polyhexamethylene biguanide, Sterile saline solution
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Periimplantitis
Adhesion of Connective Tissue Around Laser-treated Abutments for Dental Implants - Clinical Trial in Humans
This study aims to demonstrate the histological differences in the connective tissue surrounding laser-treated abutments and untreated abutments in humans.
- Trial name
- NCT01954485
- Testing
- Dental implant placement with a final prosthetic abutment
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Barcelona