Clinical trials: Pericarditis
Early Infarct-associated Pericarditis
Cardiac Magnetic Resonance for Diagnosing and Guiding Treatment in Concealed Myocardial Rupture
looking for the incidence of concealed myocardial rupture in patients with post infarct pericarditis
- Trial name
- NCT07027683
- Testing
- Cardiac MRI
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Pisa
Cardiopulmonary Failure, Myocardial Infarction (MI)
COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable
The COR-INSIGHT trial aims to evaluate the effectiveness of Peerbridge COR advanced ambulatory ECG wearables (COR 1.0 and COR 2.0) in accurately and non-invasively detecting cardiovascular and cardiopulmonary conditions using…
- Conditions
- Cardiopulmonary Failure, Myocardial Infarction (MI), Heart Decompensation, Heart Failure
- Trial name
- COR-INSIGHT (NCT06763549)
- Testing
- SUBPROTOCOL A, SUBPROTOCOL B, SUBPROTOCOL C
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Peerbridge Health, Inc
Atrial Fibrillation, Catheter Ablation
Post-Ablation Pericarditis Reduction Study (PAPERS)
There has not been a prospective, randomized controlled trial of colchicine to reduce post-AF ablation pericarditis in an era of newer AF ablation techniques.
- Conditions
- Atrial Fibrillation, Catheter Ablation, Pericarditis
- Trial name
- PAPERS (NCT06731595)
- Testing
- Colchicine
- Where
- United States
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- St. Vincent Cardiovascular Research Institute
Acute Pericarditis, Pericardial Effusion
Pericardial Fluid Analysis in Recurrent Pericarditis
This clinical trial aims to examine the biochemical and cytological features of pericardial effusion during acute and recurrent pericarditis and to understand the molecular factors responsible for pathogenesis.
- Conditions
- Acute Pericarditis, Pericardial Effusion, Pericardial Disease, Pericardial Fluid Exudate
- Trial name
- PEFLANA (NCT06293924)
- Testing
- Pericardiocentesis, Pericardiotomy, Cytofluorometry and Gene expression analysis
- Where
- Italy
- Volunteers
- 432 people
- Sponsor
- ASST Fatebenefratelli Sacco
Recurrent Pericarditis
Efficacy and Safety of RPH-104 Treatment in Patients With Recurrent Pericarditis
The primary purpose of this study is the evaluation of the efficacy and safety of RPH-104 treatment in patients with recurrent pericarditis.
- Trial name
- NCT05107934
- Testing
- RPH-104
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- R-Pharm Overseas, Inc.
Idiopathic Recurrent Pericarditis
Study of the Safety and Efficacy of RPH-104 in Preventing Recurrences in Patients With Idiopathic Recurrent Pericarditis
The goal of this clinical trial is to evaluate the safety and efficacy of RPH-104 for long-term use in a population of patients with idiopathic recurrent pericarditis who completed the main study CL04018068.
- Trial name
- NCT05673902
- Testing
- RPH-104
- Where
- Russia
- Volunteers
- 17 people
- Sponsor
- R-Pharm International, LLC
Myocarditis, Cardiac Sarcoidosis
Inflammatory Cardiomyopathy Bern Registry
Inflammatory cardiomyopathies are associated with inflammation and impaired function of the heart muscle and encompass myo- and pericarditis and cardiac sarcoidosis.
- Conditions
- Myocarditis, Cardiac Sarcoidosis, Pericarditis
- Trial name
- FlamBer (NCT04774549)
- Where
- Switzerland
- Volunteers
- 1,125 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pericarditis
Clinical Phenotypes in Pericarditis: IL-1RA Antibodies and suPAR Levels
This study aims to investigate the pathophysiology of recurrent pericarditis (RP) by testing for neutralizing autoantibodies against interleukin-1 receptor antagonist (IL-1RA) and measuring soluble urokinase plasminogen activator…
- Trial name
- PERIPLO (NCT05925790)
- Testing
- IL1RA Antibody Assay, suPAR Testing
- Where
- 9 sites in Germany, Italy
- Volunteers
- 146 people
- Sponsor
- ASST Fatebenefratelli Sacco
Inflammation, Cardiovascular Diseases
Inflammation in Acute Cardiovascular Diseases - the CArdiovascular Inflammation Registry (CAIR)
Following acute cardiovascular injury, inflammation is vital to activate reparative mechanisms. However, there is compelling evidence implicating excessive inflammation and dysregulated resolution in fibrosis, ventricular…
- Conditions
- Inflammation, Cardiovascular Diseases, Myocarditis, Pericarditis
- Trial name
- CAIR (NCT06411340)
- Testing
- Observation
- Volunteers
- 1,000 people
- Sponsor
- King's College London
Recurrent Pericarditis
Therapy Management in Patients Treated With Anakinra Due to Recurrent Pericarditis
To determine the utility of serial cardiac magnetic resonance (CMR) imaging for guidance of therapy management in patients treated with anakinra due to recurrent pericarditis (RP), compared with c-reactive protein (CRP) assay…
- Trial name
- NCT06071156
- Testing
- Anakinra
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Azienda Ospedaliero, Universitaria Ospedali Riuniti
Myocarditis, Pericarditis
ACAM2000® Myopericarditis Registry
The purpose of this registry is to study the natural history of vaccination-related myocarditis and pericarditis and to assess possible risk factors for these conditions.
- Trial name
- NCT01395082
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Emergent BioSolutions
Pericarditis Acute
Dexamethasone Compared to Non-steroidal Anti-inflammatory Drugs in the Treatment of Acute Pericarditis
The treatment of acute pericarditis is empiric and is based on treatment with medications with anti-inflammatory properties such as non-steroidal anti-inflammatory drugs (NSAID) and corticosteroids.
- Trial name
- Dexa-P (NCT04323280)
- Testing
- Dexamethasone therapy, NSAID therapy
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Rabin Medical Center
Myocarditis, Myocarditis Acute
MYocarditis and/or Pericarditis Following mRNA COVID-19 VACCination National Surveillance Study
Myocarditis is inflammation of the heart muscle. Pericarditis is inflammation of the lining surrounding the heart muscle. Symptoms of these conditions can include pain in the chest and rapid or irregular heartbeat.
- Conditions
- Myocarditis, Myocarditis Acute, Pericarditis, Pericarditis Acute
- Trial name
- MYCOVACC (NCT06103123)
- Testing
- Stand of care ECG, Holter, MRI, ECHO, Quality of life questionnaire, Baseline Quality of Life questionnaire
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Cardiology Research UBC
Recurrent Pericarditis
Study to Assess the Efficacy and Safety of Rilonacept Treatment in Participants With Recurrent Pericarditis
The primary objective of this study was to assess the efficacy of rilonacept treatment in participants with recurrent pericarditis.
- Trial name
- RHAPSODY (NCT03737110)
- Testing
- Rilonacept
- Where
- 21 sites in United States, Australia and 2 more
- Volunteers
- 86 people
- Sponsor
- Kiniksa Pharmaceuticals (UK), Ltd.
Cancer, Immune Defect
Adverse Myocardial and Vascular Side Effects of Immune Checkpoint Inhibitors
Our knowledge on cardiovascular side effects of immune checkpoint inhibitors (ICIs) is restricted to this date to observational retrospective data (mainly case series and pharamcovigilance analysis).
- Conditions
- Cancer, Immune Defect, Cardiovascular Abnormalities
- Trial name
- AMICI (NCT04586894)
- Testing
- Cardiac MRI, Smart cloth, Biobanking
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infective Pericarditis
Improvement of the Etiological Diagnosis of the Pericarditis
Pericardial syndrome includes pericardites acute pericardial effusion and cardiac tamponade, recurrent pericarditis squeezing chronic pericarditis.
- Trial name
- PERICARDITE (NCT02828085)
- Testing
- Nasal swab
- Where
- France
- Volunteers
- 979 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Pericarditis
Therapeutic Approach in Colchicine-resistant Recurrent pEricarditis in Children
The purpose of this study is to demonstrate that anakinra provides more rapid disease control than steroids in the first month of treatment in the event of recurrent pericarditis and is more effective in preventing further…
- Trial name
- CREATE (NCT05805930)
- Testing
- Anakinra, Prednisone
- Volunteers
- 48 people
- Sponsor
- Istituto Giannina Gaslini
Pericarditis Idiopathic Recurrent
Hydroxychloroquine in Colchicine-Resistant Glucocorticoid-Dependent Idiopathic Recurrent Pericarditis
Among patients with colchicine-resistant glucocorticoid-dependent idiopathic RP (idiopathic recurrent pericarditis during at least a second recurrence, having met the 2015 European Society of Cardiology criteria for pericarditis…
- Trial name
- RESTORE (NCT05737680)
- Testing
- Hydroxychloroquine, Colchicine
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- Hippocration General Hospital
Atrial Fibrillation, Catheter Ablation
Post-Ablation Pericarditis Reduction Study
There has not been a prospective, randomized controlled trial of colchicine to reduce post-AF ablation pericarditis in an era of newer AF ablation techniques.
- Conditions
- Atrial Fibrillation, Catheter Ablation, Pericarditis
- Trial name
- PAPERS (NCT04906720)
- Testing
- Colchicine
- Where
- United States
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- St. Vincent Cardiovascular Research Institute
Pericarditis
Study to Evaluate the Efficacy and Safety of RPH-104 Treatment in Patients With Idiopathic Recurrent Pericarditis
The goal of this study was to evaluate the Efficacy and Safety of RPH-104 Treatment in patients in comparison to placebo with Idiopathic Recurrent Pericarditis
- Trial name
- NCT04692766
- Testing
- RPH-104
- Where
- 2 sites in Russia
- Volunteers
- 20 people
- Sponsor
- R-Pharm International, LLC