Clinical trials: Periampullary Neoplasms
Periampullary Tumor
The Effect of ERAS on Pancreaticoduodenectomy
Enhanced Recovery After Surgery (ERAS) is not the program that aim to reduce postoperative hospital stay, but the multimodal strategies that aim to attenuate the loss of, and improve the restoration of,functional capacity after…
- Trial name
- ERAS (NCT02372331)
- Testing
- ERAS perioperative management
- Where
- South Korea
- Volunteers
- 276 people
- Sponsor
- Asan Medical Center
Adult Primary Cholangiocellular Carcinoma, Advanced Adult Primary Liver Cancer
Cediranib Maleate and Combination Chemotherapy in Treating Patients With Advanced Biliary Cancers
This phase II trial is studying how well giving cediranib maleate together with combination chemotherapy works in treating patients with advanced biliary cancers.
- Conditions
- Adult Primary Cholangiocellular Carcinoma, Advanced Adult Primary Liver Cancer, Cholangiocarcinoma of the Extrahepatic Bile Duct, Cholangiocarcinoma of the Gallbladder
- Trial name
- NCT01229111
- Testing
- cediranib maleate, oxaliplatin, leucovorin calcium
- Where
- 7 sites in United States
- Volunteers
- 14 people
- Sponsor
- National Cancer Institute (NCI)
Periampullary Carcinoma Nos
Effect of Probiotics in Patients Undergoing Surgery for Periampullary Neoplasms
The purpose of this study is to evaluate the effect of the probiotic use in patients with periampullary cancers undergone curative or palliative treatment considering nutritional status, postoperative complications, infection…
- Trial name
- NCT01468779
- Testing
- Probiotics, Sugar pill
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pancreatic Cancer, Pancreatic Adenocarcinoma
EUS BD vs ERCP TP for Pancreatic Cancer
This Endoscopic Ultrasound guided Biliary Drainage (EUS-BD) vs. Endoscopic Retrograde Cholangiopancreatography (ERCP-TP) trial (BILPAL) is a randomized controlled multicenter trial that will provide evidence whether or not…
- Conditions
- Pancreatic Cancer, Pancreatic Adenocarcinoma, Biliary Tract Neoplasms, Biliary Duct Obstruction
- Trial name
- BILPAL (NCT03063554)
- Testing
- Endoscopic Ultrasound Guided Biliary Drainage, ERCP
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Weill Medical College of Cornell University
Periampullary Carcinoma Resectable, Pancreaticoduodenectomy
Early Oral Intake After Pancreaticoduodenectomy in the Age of ERAS
Early oral intake after Pancreaticoduodenectomy is recommended strongly according to the ERAS guideline, which was based on studies in patients with gastrointestinal cancer, mainly colorectal and gastric.
- Trial name
- NCT02941484
- Testing
- early oral intake, jejunostomy tube feeding (JTF)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xuzhou Medical University
Pancreas Cancer, Periampullary Cancer
Reconstruction Following Pancreaticoduodenectomy: A Randomized Clinical Trial of Pancreaticojejunostomy vs Pancreaticogastomy
Pancreaticoduodenectomy (PD or Whipple procedure) involves the removal of the head of the pancreas and is the primary modality for treatment of peri-ampullary cancers (arising from the common bile duct, Ampulla of Vater…
- Trial name
- NCT00841607
- Testing
- pancreaticojejunostomy vs pancreaticogastrostomy
- Where
- Canada
- Volunteers
- 162 people
- Sponsor
- Tom Baker Cancer Centre
Periampullary Tumors
Impact of Prophylactic Octreotide to Pancreatic Exocrine Secretion
This study aims to examine whether octreotide has an effect on inhibition of the exocrine secretion fo the pancreas, which might lower the rate of postoperative pancreatic fistula after pancreatoduodenectomy.
- Trial name
- NCT02920567
- Testing
- Octreotide
- Where
- South Korea
- Volunteers
- 282 people
- Sponsor
- Saint Vincent's Hospital, Korea
Stage, Pancreatic Cancer, Neoplasm, Residual
Multicolour Versus Monocolour Specimens Inking After Pancreaticoduodenectomy for Periampullary Cancer
A single-centre, randomised clinical trial of patients affected by periampullary cancer who underwent pancreaticoduodenectomies which included two different types of specimen margination: arm A (multicolour inking) and arm B…
- Conditions
- Stage, Pancreatic Cancer, Neoplasm, Residual, Pancreatic Neoplasm, Periampullary Cancer
- Trial name
- MPM (NCT02900950)
- Testing
- Multicolour inking specimens, Monocolour inking specimens
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Obstructive Jaundice, Periampullary Tumour
Metal or Plastic Stents to Relieve Obstruction of Obstructive Jaundice Prior to Resection of Periampullary Tumors.
Patients with obstructive jaundice due to periampullary tumor can temporarily be relieved of their jaundice with transpapillary stenting at endoscopic retrograde cholangio-pancreatography (ERCP) prior to operation.
- Trial name
- SEMS (NCT02166840)
- Testing
- Plastic stent (7-10Fr), Self Expanding Metal Stent
- Where
- Sweden
- Volunteers
- 92 people
- Sponsor
- Karolinska University Hospital
Periampullary Cancer, Complications of Surgical Procedures or Medical Care
Comparison Between Fully Covered Metal Stents and Plastic Stents in Preoperative Biliary Drainage
This study is a prospective, randomized study to compare of outcome of fully covered metal stents with that of plastic stents for preoperative biliary drainage in distal common bile duct cancer, pancreas head cancer or ampullary…
- Conditions
- Periampullary Cancer, Complications of Surgical Procedures or Medical Care, Disorder of Bile Duct Stent
- Trial name
- NCT01789502
- Testing
- Fully covered metal stents, Plastic stents
- Where
- 3 sites in South Korea
- Volunteers
- 86 people
- Sponsor
- Inje University
Pancreatic Cancer, Periampullary Adenocarcinoma
Capecitabine, Vorinostat, and Radiation Therapy in Treating Patients With Nonmetastatic Pancreatic Cancer
RATIONALE: Drugs used in chemotherapy, such as capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00983268
- Testing
- capecitabine, vorinostat, Radiotherapy
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Periampullary Cancers With Obstructive Jaundice, Pancreas Head Cancer
Comparison Between Internal and External Preoperative Biliary Drainage in Periampullary Cancers
Preoperative biliary drainage methods include percutaneous transhepatic biliary drainage (PTBD), endoscopic nasobiliary drainage (ENBD), and endoscopic retrograde biliary drainage (ERBD).
- Conditions
- Periampullary Cancers With Obstructive Jaundice, Pancreas Head Cancer, Bile Duct Cancer, Ampulla of Vater Cancer
- Trial name
- NCT01134276
- Testing
- biliary drainage
- Where
- South Korea
- Volunteers
- 211 people
- Sponsor
- Seoul National University Hospital
Pancreatic Cancer, Periampullary Carcinoma
Evaluation of Preoperative Biliary Drainage Before Pancreatoduodenectomy
The purpose of this study is to evaluate the efficacy of preoperative biliary drainage (PBD) which is performed prior to pancreatoduodenectomy candidates with obstructive jaundice by observing the prevalence of drainage and…
- Trial name
- NCT01941342
- Testing
- Pancreatoduodenectomy, ENBD and Pancreatoduodenectomy, EBD and Pancreatoduodenectomy
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Southwest Hospital, China
Pancreatic Cancer, Periampullary Carcinoma
Evaluation of A New Digestive Reconstruction Procedure Following Pancreatoduodenectomy
The purpose of this study is to evaluate the validity and safety of a modified operative procedure of digestive tract reconstruction following pancreatoduodenectomy which enables the pancreatic juice and bile to bypass at the…
- Trial name
- NCT01931449
- Testing
- Modified method of digestive tract reconstruction, Routine digestive tract reconstruction
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Southwest Hospital, China
Biliary Tract Cancer, Periampullary Adenocarcinoma
SOX Sequential S-1 in Advanced Biliary Tract Carcinoma（BTC）and Pancreatic Cancer
This is an exploratory, single-armed, open label study on the efficacy and safety of sequential S-1 therapy after SOX in unresectable metastatic or locally advanced biliary system or periampullary cancer or pancreatic cancer…
- Conditions
- Biliary Tract Cancer, Periampullary Adenocarcinoma, Pancreatic Cancer
- Trial name
- NCT01811277
- Testing
- SOX sequential S-1
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Peking University
Periampullary Neoplasms
Endoscopic Ultrasound Staging of Periampullary Neoplasms: Retrospective
The purpose of this retrospective study is to determine the degree to which a biliary stent affects EUS staging accuracy of ampullary tumors.
- Trial name
- NCT00880633
- Where
- United States
- Sponsor
- Indiana University
Periampullary Carcinoma Nos
Pancreas-sparing Duodenectomy Versus Pancreatoduodenectomy for Early-stage Periampullary Carcinoma
The purpose of this study is to investigate the feasibility, safety, and long-term prognosis of pancreas-sparing duodenectomy with regional lymphadenectomy in the treatment of early-stage (pTis/pT1/pT2) periampullary carcinoma…
- Trial name
- NCT01291927
- Testing
- Pancreas-sparing duodenectomy, Pancreaticoduodenectomy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Southwest Hospital, China