Clinical trials: Peri-implantitis
Periodontitis, Peri-implant Mucositis
Biological Responses Affecting Early-stage Dental Implant Placement in Patients With History of Periodontitis
This prospective parallel, double-blind, four-arm randomised controlled clinical study is planned to assess the difference in the level of the inflammatory biomarkers expressed following the placement of the first dental implant…
- Conditions
- Periodontitis, Peri-implant Mucositis, Peri-Implantitis
- Trial name
- NCT05834946
- Testing
- Megagen implant placement, Biomate-Swiss implant
- Where
- Malaysia
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Biological Markers; Dental Implants; Cytokines; Triclosan; Toothpastes; Peri-Implantitis; Microbiology
Impact of a Triclosan-containing Toothpaste During the Progression of Experimental Peri-implant Mucositis
The aim of this study was to evaluate the influence of a triclosan-containing toothpaste in the profile of osteo-immunoinflammatory mediators in the peri-implant crevicular fluid (PICF) and in the clinical parameters during the…
- Trial name
- NCT03145610
- Testing
- triclosan/copolymer/fluoride toothpaste
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Paulista University
Peri-Implantitis, Peri-implant Mucositis
Association Between Smoking Habit and Peri-implant Diseases: a Case Control Study
Although smoking has been proposed as well, as a risk factor/indicator for peri-implantitis, there is currently no conclusive evidence. The current literature confronts the inconclusive evidence of tobacco for a risk factor.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Bone Loss, Alveolar
- Trial name
- NCT04952428
- Testing
- Re-examination visit ("today visit")
- Where
- Spain
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Periimplantitis, Periodontitis
Evaluation of the Effects of Routine Phase I Periodontal Therapy on Clinical Parameters and Levels of Gremlin-1, CTHRC1, and Tenascin-C in Gingival Crevicular Fluid and Peri-Implant Sulcular Fluid in Individuals With Periodontitis and Peri-Implantitis
The aim of this study is to compare the mechanisms of tissue destruction between natural teeth with periodontitis and implants with peri-implantitis within the same individual, and to evaluate the effects of routine Phase I…
- Trial name
- NCT07797127
- Testing
- Routine Phase I Non-Surgical Periodontal Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Peri-Implant Health, Peri Implant Mucositis
Free Amino-acid Composition of Peri-implant and Periodontal Conditions
Peri-implant diseases, encompassing peri-implant mucositis and peri-implantitis, are biologically driven inflammatory conditions that threaten the long-term success of dental implants.
- Conditions
- Peri-Implant Health, Peri Implant Mucositis, Peri Implantitis
- Trial name
- AAs (NCT07187323)
- Testing
- Saliva sampling, Amino Acid Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Peri-Implantitis, Mucositis
Exploring the Relationship Among Dental Caries, Nutritional Habits and Peri-implantitis
Aim: A study was made of the prevalence, co-occurrence and association among caries, nutritional habits and peri-implant disease, with an analysis of the influence of other patient and implant factors upon peri-implant disease.
- Conditions
- Peri-Implantitis, Mucositis, Caries,Dental, Nutrition
- Trial name
- NCT04439877
- Testing
- Peri-implant disease diagnosis
- Where
- Spain
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Peri-Implantitis
HIF-1 Alpha, VEGF and MMP-8 Levels in PICF of Smokers Versus Non Smokers
Smoking is a major risk factor for developing peri-implantitis so the current study is comparing inflammatory markers in smokers versus non smokers to know if they have a potential role in pathogenesis of peri-implantitis
- Trial name
- NCT05325918
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Peri-Implantitis
Dental Hygiene and Peri-Implant Tissues Homeostasis
Dental implants have revolutionized the field of dentistry, providing improvements in function and esthetics. They are not, however, without risks. Bone loss around implants (i.e.
- Trial name
- NCT03384446
- Testing
- Tooth-borne treatment, Implant-specific treatment
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Washington
Peri-Implantitis, Alveolar Bone Loss
Non-Surgical Treatment of Peri-Implantitis With Ultrasonic Carbon Tip
As the frequency of dental implants increases, the incidence of complications and peri-implant diseases also increases. Early diagnosis and treatment of the disease is important to prevent consequences up to implant loss.
- Trial name
- NCT06514677
- Testing
- Ultrasonic Carbon Tip, Titanium Curette
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Periimplantitis, Periimplant Diseases
Non-surgical Treatment of Peri-implantitis Using Chitosan Brush and Tetracycline Slurry
Aim: The aim of this prospective, randomized, parallel arm, blind clinical trial is to compare the clinical and radiographic outcomes following non-surgical treatment of mild peri-implant defects using Labrida Bioclean with or…
- Trial name
- NCT06695559
- Testing
- Labrida Bioclean, Tetracycline slurry
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Peri-Implantitis
Peri-implantitis Treatment: Clinical Results of Conventional Treatment vs. the Addition of Biolase
The purpose of the study is to observe the effects of two commonly utilized treatment modalities to treat peri-implantitis and to compare the results.
- Trial name
- NCT03544515
- Testing
- Er,Cr:YSGG laser, Scaling, Inactive Er,Cr:YSGG
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Columbia University
Implant, Peri-Implantitis
Efficacy of Diode Laser in Peri-implantitis
The aim of this study was to compare the efficacy of a diode laser (DL) as an adjunct to conventional scaling in the treatment of mild-to-moderate peri-implantitis.
- Conditions
- Implant, Peri-Implantitis, Alveolar Bone Loss, Complications
- Trial name
- NCT02362854
- Testing
- Conventional peri-implantitis treatment, DL application in peri-implantitis
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Peri-Implantitis
Health of Peri-implant Tissues Adjacent to Zirconia
Background: The control and maintenance of implants, bone tissue and soft tissue are fundamental for the clinical success of implant prostheses (PSIs).
- Trial name
- NCT05081076
- Testing
- Glazing, Polishing
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Dental Plaque, Oral Biofilm
Investigation of Biofilm Formation on Temporary push-on Rings of Implant Crowns
This in-vivo study investigates early (48h), mature (2 weeks) and long-term (3 months) biofilm formation and composition on temporary push-on cones (exchangeable conical rings) made of noble-alloy-based materials (Pagalinor, PA)…
- Conditions
- Dental Plaque, Oral Biofilm, Peri-implantitis
- Trial name
- NCT05122897
- Testing
- Rings made of PA (test), Rings made of TAN (control)
- Where
- Switzerland
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Peri-Implantitis, Bleeding of Subgingival Space
Incidence of Bleeding on Probing as an Indicator of Peri-Implant Disease Progression
The primary goal of the present prospective cohort study is to evaluate the effect of varying incidences of BOP at implant sites across 15 months of maintenance visits on the probability of peri-implant disease progression.
- Trial name
- BOP (NCT06033859)
- Testing
- Clinical measurements, Radiographic measurement, Dental prophylaxis or maintenance
- Where
- United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Peri-Implantitis, Peri-Implant Health
Comparison of the Effectiveness of Two Different Surgical Therapeutic Protocols of Peri-implantitis
The purpose of the present study is to compare the 1-year clinical, radiographic and microbiological outcomes and patients' satisfaction following surgical treatment of peri-implantitis after applying two different surface…
- Trial name
- NCT05899933
- Testing
- Non-surgical peri-implant therapy, Implantoplasty, Erythritol Air-abrasive device
- Where
- Greece
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Local Anesthesia, Dental Implants
Comparison of Anesthetic Efficacy and Safety Between Inferior Alveolar Nerve Block and the Infiltrative Technique for the Treatment of Peri-implant Diseases in Posterior Mandibular Implants
This triple-blind randomized clinical trial aims to compare the anesthetic efficacy and safety of two local anesthesia techniques for the surgical treatment of peri-implantitis in posterior mandibular implants: inferior alveolar…
- Conditions
- Local Anesthesia, Dental Implants, Periimplantitis
- Trial name
- NCT07590037
- Testing
- Comparison of anesthetic efficacy and safety between nerve block and infiltrative technique for periimplantitis surgical treatment in poosterior mandibular implants
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Peri Implantitis, Peri Implant Mucositis
Evaluation of 25(OH)D3 and LL-37 Levels in Periimplant Sulcus Fluid
Despite technological advances that have significantly improved dental implant osseointegration and survival rates, biological complications such as peri-implantitis and peri-implant mucositis are common around the implant.
- Trial name
- NCT07280754
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Periimplantitis, Microbial Colonization
The Effect of Smoking on Peri-implantitis
the primary aim of this project is to evaluate the microbiological and inflammatory effect of smoking status and smoking severity on periimplantitis lesions.
- Conditions
- Periimplantitis, Microbial Colonization, Cytokines
- Trial name
- NCT06150066
- Testing
- Recruiting samples
- Where
- 2 sites in Switzerland, Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Peri-Implantitis
Er,Cr:YSGG Laser Application in Peri-implantitis
In the present study, investigators, aimed to evaluate the effect of erbium, chromium:yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser application combined with mechanical debridement (MD) on clinical parameters and biochemical…
- Trial name
- NCT06031467
- Testing
- Er, Cr: YSGG laser-assisted non-surgical mechanical therapy, Non-surgical mechanical therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University