Clinical trials: Peri-Implant Tissues
Peri-Implantitis
Soft Tissue Assessment in Screw-Retained Maxillary Complete Denture With Electric Welded Framework Versus Casted
comparing the changes in the soft tissue around the implants that will be joined by a metal framework either with electric welding or with the conventional casting method
- Trial name
- NCT04543864
- Testing
- Electric intraoral welding device, casting
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Peri-implant Soft Tissue Healing
Comparison of BioHPP (High Performance Polymer) - vs Titanium- vs Zirconia Abutments
The project is a prospective, randomized, controlled study. The material BioHPP (High Performance Polymer) is compared with the gold-standard abutment materials titanium and zirconia in terms of peri-implant soft tissue healing.
- Trial name
- NCT06737263
- Testing
- BioHPP abutment, Titanium abutment, Zirconia abutment
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Graz
Peri-Implant Mucositis
Short Versus Standard Dental Implants: Clinical and Biomarker Outcomes
This study compares two types of dental implants, short implants (6 millimeters or less in length) and standard implants (longer than 8 millimeters), to evaluate their effect on the health of the gum and bone tissue surrounding…
- Trial name
- NCT07828067
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Inonu University
Periodontitis, Peri-implant Mucositis
Biological Responses Affecting Early-stage Dental Implant Placement in Patients With History of Periodontitis
This prospective parallel, double-blind, four-arm randomised controlled clinical study is planned to assess the difference in the level of the inflammatory biomarkers expressed following the placement of the first dental implant…
- Conditions
- Periodontitis, Peri-implant Mucositis, Peri-Implantitis
- Trial name
- NCT05834946
- Testing
- Megagen implant placement, Biomate-Swiss implant
- Where
- Malaysia
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Partial Edentulism, Dental Implants
Comparison of Two Dental Implant Types and Placement Depths on Bone Around the Implant in Adults Missing Back Teeth
The goal of this clinical trial was to compare two ways of placing and restoring dental implants in adults missing one or more back teeth.
- Conditions
- Partial Edentulism, Dental Implants, Alveolar Bone Loss
- Trial name
- NCT07886762
- Testing
- issue-level implant placed at crestal level (Klockner Essential Cone), Bone-level implant placed 2 mm subcrestally with one-abutment-one-time protocol (Klockner Vega)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Markel Diéguez-Pereira
Dental Implant
Subepithelial Connective Tissue Graft Versus Amniotic Chorion Membrane for Peri-implant Mucosal Thickness Enhancement
The objective of this study will be to assess the efficacy of the peri-implant mucosal thickness enhancement following either subepithelial connective tissue grafts or Amnion Chorion Membrane placed simultaneously with dental…
- Trial name
- NCT06295653
- Testing
- implant placement and soft tissue augmentation with Autogenous Subepithelial Connective Tissue Graft or Amniotic Chorion Membrane
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Tanta University
Periimplantitis
Comparison of Denture Base Adaptation and Per-iimplant Tissue Health Between CAD and CAM Implant Overdenture
Background: Complete overdenture manufacturing has been greatly developed using computer-aided designing and computer-aided manufacturing (CAD-CAM) technology.
- Trial name
- NCT06166446
- Testing
- subtractive technique, additive technique
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Alveolar Bone Loss, Partially Edentulous Jaw
Impact of Hyaluronic Acid and Bone Graft on Peri-Implant Tissue
This randomized controlled clinical trial aims to evaluate the effect of hyaluronic acid (HA) and particulate bone graft on the peri-implant tissue phenotype in patients receiving dental implants.
- Conditions
- Alveolar Bone Loss, Partially Edentulous Jaw, Dental Implant
- Trial name
- NCT07665281
- Testing
- Dental Implants with Hyaluronic Acid, Dental Implants with Hyaluronic Acid and Particulate Bone Graft, Standard Dental Implants Placement only
- Where
- 2 sites in Iraq
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Breast Cancer
SPY Intra-Operative Angiography & Skin Perfusion in Immediate Breast Reconstruction w/ Implants
The investigators hope to learn the value of the SPY ELITE® intra-operative angiography in reducing post-operative complications associated with low breast skin blood flow after breast reconstruction using implants.
- Trial name
- NCT01315119
- Testing
- SPY Intra-Operative Angiography
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Peri-implant Bone Loss, Peri-Implant Tissues
Ten Year Follow up of Convergent Profile Implants
The aim of the study is to evaluate the marginal bone level (MBL) and pink aesthetic score (PES) changes on the short, medium and long-term, on a retrospective cohort of patients who received at least one "biotype implant" (DEI…
- Trial name
- NCT07089407
- Testing
- Dental implant placement
- Where
- Italy
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Dental Implant
Effect of Bone Graft Material ON Peri-Implant Phenotype .
This prospective three-arm controlled interventional clinical study evaluates the effects of NanoBone alone and NanoBone combined with platelet-rich fibrin (PRF) on peri-implant hard and soft tissue phenotype after dental implant…
- Trial name
- NCT07835451
- Testing
- Dental implant placement, NanoBone, NanoBone sticky bone plus CGF/PRF membrane
- Where
- Iraq
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Dental Implant, Prosthetic Abutment
One-time Abutment Placement Versus 4 Times Abutment Removal Around Dental Implants
Introduction: the repeated connection and disconnection of healing abutments during dental implants´ osseointegration has been associated with significant increased peri-implant bone loss, when compared with placing the final…
- Trial name
- NCT05711147
- Testing
- Abutment removal, Placement of definitive abutment
- Where
- Spain
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Complete Edentulism
Microbial Adhesion and Peri-Implant Tissue Health in All-on-Four Hybrid Prostheses Supported by Zantex or Zirconia Frameworks
This study compares two materials (Zantex and Zirconia) used to make fixed full-arch dental prostheses supported by four dental implants (the "All-on-Four" technique) in patients who have no natural teeth in the lower jaw.
- Trial name
- NCT07811661
- Testing
- Zirconia Framework, Zantex Framework
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Kafrelsheikh University
Antibiotic
The Effect of Different Antibiotic Protocols on Peri-implant Tissue Health
The aim of the present project (non-inferiority trial) is to evaluate the effect of different antibiotic strategies (long-span vs.
- Trial name
- NCT06378502
- Testing
- Amoxicillin Short, Amoxicillin Long
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universita degli Studi di Genova
Implant Therapy, Biological Width
Histological Analysis of Peri-implant Soft Tissue
The aim of this study is to evaluate the histologically analysis in humans and the orientation of collagen fibers around screw-less, morse taper implant-abutment connection.
- Trial name
- NCT06862505
- Testing
- Biopsy
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Soft Tissues According to the Abutment Torque, Microleakage Accordint to the Abutment Torque
Impact of Abutment Screw Torque on Marginal Bone Loss
The objective of this clinical trial is to evaluate the impact of different torque values applied during transmucosal abutment placement in dental implants on marginal bone loss and peri-implant parameters, including the…
- Conditions
- Soft Tissues According to the Abutment Torque, Microleakage Accordint to the Abutment Torque, PROMS According to the Abutment Torque, Marginal Bone Loss According to the Abutment Torque
- Trial name
- NCT07234552
- Testing
- Abutment torqued to 15 Ncm, Pilar torqued to 30 Ncm, 2 mm healing cap
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Keratinized Mucosa
The Impact of Peri-implant Soft Tissue Properties on Patient-reported and Clinically Assessed Outcomes
The objective of this study is to evaluate patient discomfort while performing oral hygiene (OH) around implants with and without keratinized mucosa (KM) and assess peri-implant soft tissue esthetic satisfaction and other…
- Trial name
- NCT03396536
- Testing
- Evaluation of KM
- Volunteers
- 43 people
- Sponsor
- Tufts University
Peri-implantitis
Effect of Metallic Particles on the Progression of Peri-Implantitis
This observational cross-sectional study aims to investigate the presence and characteristics of metallic micro- and nanoparticles in peri-implant tissues and their potential association with peri-implantitis progression, the…
- Trial name
- NCT07792499
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Immediate Implant, Connective Tissue Graft
Xengenic Cortical Membranes Versus Connective Tissue Graft With Coronally Advanced Flap for the Treatment of Peri-implant Soft Tissue Dehiscences: A Randomized, Controlled Clinical Trial
Peri-implant soft tissue dehiscences represent a common complication in implant dentistry, often leading to esthetic and functional challenges.
- Trial name
- NCT06588998
- Testing
- Xengenic Cortical membranes, connective tissue graft
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Amr Anwar Mohamed Ellithy Yousef
Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement, Immediate Dental Implant Placement
Influence of Provisional Restoration Type on Outcomes of Immediate Implant Placement and Loading
A randomized clinical trial comparing 3D-printed resin and CAD/CAM-milled PMMA provisional restorations used for immediate loading of fully digitally guided immediate implants.
- Conditions
- Tooth Loss in the Esthetic Zone Requiring Immediate Implant Placement, Immediate Dental Implant Placement, Immediate Loading, Provisional Restoration
- Trial name
- PRODIGI (NCT07700771)
- Testing
- 3D-Printed Resin Provisional Crown, CAD/CAM-Milled PMMA Provisional Crown
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University