Clinical trials: Penis/Surgery
Concealed Penis
Surgical Repair of Pediatric Concealed Penis is Generally Safe and Efficacious. Criteria for Pediatric Concealed Penis Surgical Success Are Still Poorly Standardized, so Our Study Presents a Multi-dimensional Framework Consisting of Morphometric Measurements and Subjective Psychometric Parameters.
A concealed penis (CP) refers to a condition in which the normally-sized penis appears smaller or completely hidden in the prepubic area. Surgical repair of pediatric concealed penis is generally safe and efficacious.
- Trial name
- MPPPS SPL BPL (NCT07615439)
- Testing
- penoplasty by complete penile degloving to release all anomalous restrictive attachments, followed by phallopexy via proper fixation of the penile base
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Eslam Saad Hamza
Hypospadias Repair Surgery
Comparison of the Efficacy of Bupivacaine with and Without Dexmedetomidine As an Adjuvant on Penile Block for Postoperative Pain Relief in Pediatrics Undergoing Hypospadias Repair Surgery
The main issue with pain management in children especially young children is the difficulty involved in evaluating it. When a patient's level of pain cannot be accurately assessed, effective analgesia cannot be prescribed.
- Trial name
- NCT06789393
- Testing
- Dexmedetomidine, Bupivacaine
- Volunteers
- 80 people
- Sponsor
- Assiut University
Urologic Cancer, Urologic Neoplasms
A Novel Imaging Protocol in Use to Identify Lymph Nodes and Organs of Interest
This research study is a pilot clinical trial, which hypothesizes that the combination of electromagnetic tracking in conjunction with laparoscope imaging and ultrasound probe imaging will aid in reducing the complexity of both…
- Conditions
- Urologic Cancer, Urologic Neoplasms, Bladder Cancer, Prostate Cancer
- Trial name
- NCT05899361
- Testing
- Electromagnetic Guided Laparoscopy, Ultrasound
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Brigham and Women's Hospital
Penile Cancer, Recurrent
Prediction of Local Recurrence and Its Impact on Long-term Outcomes After Low-risk Glans-sparing Surgery for Penile Squamous Cell Carcinoma
The treatment paradigm for primary penile squamous cell carcinoma (PSCC) has increasingly favored maximal organ preservation without compromising oncological outcomes.
- Trial name
- NCT06565585
- Testing
- Glans-sparing surgery
- Where
- Belgium
- Volunteers
- 800 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hypospadias, Undescended Testis
Visual Guidelines and Tutoring in Pediatric Urological Surgery
The aim of this study is checking impact of visual guidelines (picture book) and tutoring in pediatric urologic surgery
- Conditions
- Hypospadias, Undescended Testis, Hydrocele, Ureteropelvic Junction Stenosis
- Trial name
- NCT02040389
- Testing
- Picture book, Standard preoperative education
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Shaare Zedek Medical Center
Gender Dysphoria, Gender Dysphoria, Adult
Metoidioplasty and Phalloplasty Surgery Decision Making
The goal of this clinical trial is to test a new online tool designed to provide clear and understandable information to help individuals considering Metoidioplasty and Phalloplasty Surgeries (MaPS) make informed decisions The…
- Conditions
- Gender Dysphoria, Gender Dysphoria, Adult, Gender Incongruence, Transgenderism
- Trial name
- MaPS (NCT06565663)
- Testing
- MaPS Decision Aid
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Hypospadia, Phimosis
Intelligence Changes Following Minor Surgery
Animal studies showed that many general anesthetics might result in neuron apoptosis and neurocognitive impairment in the developing brain. However results from human studies are conflicted.
- Conditions
- Hypospadia, Phimosis, Inguinal Hernia
- Trial name
- NCT01483313
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- RenJi Hospital
Ultrasound Imaging, Caudal Block
Out Of-plane Technique Against In-plane for Caudal Block
Caudal block is an easy and effective type of central neuraxial block that is widely used in subumbilical surgeries to provide intraoperative and postoperative analgesia in the pediatric population.
- Conditions
- Ultrasound Imaging, Caudal Block, Hypospadias
- Trial name
- NCT04671992
- Testing
- Out of-Plane Technique and In-Plane on
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Pain, Postoperative
Saddle Block With IT Morphine for Penile Inversion Vaginoplasty
Penile Inversion Vaginoplasty (PIV) is a transition-related surgery (TRS) that is associated with severe postoperative pain. The optimal pain management strategies for this surgery remain unknown.
- Trial name
- NCT06556121
- Testing
- Saddle block, pudendal nerve block
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Women's College Hospital
Phimosis
The Best Dose of Esketamine for Day Surgery of Pediatric Circumcision Pediatric Circumcision
In recent years, daytime operation has been developed gradually in China. Circumcision in children is a common type of daytime operation.
- Trial name
- NCT04698434
- Testing
- Esketamine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Yangzhou University
Hypospadias, Anesthesia; Adverse Effect
The EPigenetic Consequences in Children of Intravenous vs Volatile Anaesthesia for Surgery (EPIVA)
More than half a million children have an anaesthetic each year in the UK. Though anaesthesia is usually thought to be safe and necessary to improve health, concerns remain the effects that the drugs used may have on brain…
- Conditions
- Hypospadias, Anesthesia; Adverse Effect, Perioperative Complication, Pediatric ALL
- Trial name
- EPIVA (NCT05936853)
- Testing
- Intravenous approach to anaesthetic maintenance, Inhalational approach to anaesthetic maintenance
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Sacral Erector Spinae Plane Block, Caudal Block
Sacral Erector Spinae Plane Block Versus Caudal Block in Penile Surgeries in Pediatrics
The study will be conducted to compare the efficacy of ultrasound guided Sacral Erector Spinae Plane Block to caudal block on pain management in penile surgeries in pediatrics.
- Conditions
- Sacral Erector Spinae Plane Block, Caudal Block, Penile Surgeries, Pediatrics
- Trial name
- NCT06235944
- Testing
- Caudal block, Sacral erector spinae block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Hypospadias
Efficacy of Fibrin Sealant in Hypospadias Surgery
The aim of the study was to evaluate if application of a fibrin sealant over the urethroplasty suture line for waterproofing instead of a dartos vascularized pedicled flap to reduce complications and improve the outcome in…
- Trial name
- NCT05666206
- Testing
- fibrin sealant in hypospadias
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Al-Azhar University
Postoperative Pain
Pudendal vs Caudal Block for Pediatric Penile Surgery
The study will compare recovery profile in children receiving pudendal blocks vs caudal analgesia for ambulatory circumcision or hypospadias repair in children between 6 months and 2 years.
- Trial name
- NCT04840654
- Testing
- Caudal Block, Pudendal Block
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Chicago
Squamous Cell Carcinoma of the Penis, Usual Type
International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study)
This is an international phase III trial, with a Bayesian design, incorporating two sequential randomisations. It efficiently examines a series of questions that routinely arise in the sequencing of treatment.
- Trial name
- InPACT (NCT02305654)
- Testing
- ILND - Inguinal Lymph Node Dissection, Paclitaxel, Ifosfamide
- Where
- 17 sites in United States, United Kingdom
- Volunteers
- 200 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Penile Injection Therapy, Erectile Dysfunction
Penile Injection Anxiety
The purpose of this study is to help us understand more about your experience with penile injection therapy. Many men become anxious when thinking about penile injections. We would like to understand more about this anxiety.
- Conditions
- Penile Injection Therapy, Erectile Dysfunction, Radical Pelvic Surgery
- Trial name
- NCT00582231
- Testing
- Questionnaires.
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Hypospadias, Postoperative Pain
Caudal Epidural Block and DPNB in Hypospadias
Hypospadias, seen in every 200-300 births, is one of the most common congenital anomalies of the penis and is defined as the urethral meatus being located in the ventral part of the penis instead of its normal place.
- Trial name
- NCT04215874
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Complication of Surgical Procedure
Outcomes of Surgical Correction of Penile Curvature in Adult
Penile curvature in adults is divided into two main categories the first is congenital penile curvature with orthotopic meatus and the other is acquired curvature which its common causes are Peyronie's disease (PD) and previous…
- Trial name
- NCT03313986
- Volunteers
- 50 people
- Sponsor
- Assiut University
Postoperative Analgesia
Comparison of the Effects of Sacral Erector Spinae Plane Block and Dorsal Penile Block on Postoperative Pain in Circumcision Procedures
Egypt performed circumcision in 2300 BC, although its origin is unknown. Some societies use circumcision for health, whereas others do it for religious and cultural reasons .
- Trial name
- NCT06843070
- Testing
- PENILE BLOCK ARM, SACRAL ESP BLOCK ARM
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Hypospadias, Surgery Non Hypospadias
Glans Size in Hypospadias Compared to Normal
The investigator will collect data on penile and glans size by age, weight and ethnicity in both patients undergoing routine urological surgery and hypospadias surgery.
- Trial name
- NCT03593720
- Testing
- Measurement in Office, Measurement in OR
- Where
- United States
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Albany Medical College