Clinical trials: Penile Diseases
Phimosis, Paraphimosis
Evaluating the Efficacy of 2-Octyl Cyanoacrylate (2-OCA) With Four Interrupted Sutures in Adult Male Circumcision
This study aims to determine whether cyanoacrylate glue is a non-inferior alternative to continuous suturing for wound closure following adult circumcision.
- Trial name
- NCT06487494
- Testing
- Circumcision wound closure using 2-octyl cyanoacrylate glue with four interrupted sutures, Circumcision wound closure using continuous sutuing
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Sickle Cell Disease, Priapism
Sildenafil for Treatment of Priapism in Men With Sickle Cell Anemia
This research is being done to evaluate if the phosphodiesterase type 5 (PDE5) inhibitor sildenafil has an effect on the frequency of recurrent priapism and the quality of life of males with sickle cell disease (SCD).
- Trial name
- NCT00940901
- Testing
- sildenafil
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Johns Hopkins University
Prostate Cancer
Prevalence of Neglected Side Effects to Radical Prostatectomy
The purpose of this exploratory data collection is to strengthen our knowledge of some of the rarer distresses following surgical removal of the prostate.
- Trial name
- NCT01742962
- Testing
- Radical prostatectomy for prostate cancer
- Where
- Denmark
- Volunteers
- 396 people
- Sponsor
- Copenhagen University Hospital at Herlev
Peyronie's Disease
Real-World Data Study to Understand Effectiveness of Treatments in Peyronie's Disease
This is an observational study, meaning participants will not receive any investigational treatment as part of this study. Researchers will collect real-world data (RWD) to gain a more in-depth knowledge of the treatment of…
- Trial name
- CURVE-PD (NCT05873595)
- Where
- 7 sites in United States
- Volunteers
- 29 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Peyronie's Disease, Hyaluronic Acid
Intralesional Hyaluronic Acid and Verapamil Injection in Peyronie's Disease
The aim of the present study is to investigate whether intralesional injections of Hyaluronic acid in the acute phase could reduce the progression of Peyronie's disease thanks to its interference with inflammatory and…
- Conditions
- Peyronie's Disease, Hyaluronic Acid, Verapamil
- Trial name
- NCT05855070
- Testing
- Intralesional treatment with Hyaluronic acid, Intralesional treatment with Verapamil
- Volunteers
- 42 people
- Sponsor
- Benha University
Erectile Dysfunction
Registry for Patients Undergoing Penile Prosthesis Implantation for Male Erectile Dysfunction
Prospective collection of pre-defined parameters on the surgical treatment of male erectile dysfunction using Penile Prosthesis Implants (PPIs).
- Trial name
- PHOENIX (NCT03849586)
- Where
- 30 sites in Belgium, France and 6 more
- Volunteers
- 1,076 people
- Sponsor
- European Association of Urology Research Foundation
Penile Cancer, Advanced Cancer
A Study of Avelumab in Penile Cancer Who Are Unfit for or Have Progressed After Platinum-Based Chemotherapy
This is a phase 2 study whose purpose is see how useful investigational drug, avelumab, is in patients with locally advanced or metastatic penile cancer who are unfit for or progressed on platinum-based chemotherapy.
- Conditions
- Penile Cancer, Advanced Cancer, Metastatic Cancer
- Trial name
- NCT03391479
- Testing
- Avelumab, Best Supportive Care
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University Health Network, Toronto
Penile Cancer
QL1706 Plus Lenvatinib in Previously Treated Penile Cancer
This phase II clinical study aims to evaluate the efficacy and safety of QL1706 in combination with lenvatinib in patients with previously treated advanced or metastatic penile squamous cell carcinoma.
- Trial name
- NCT07384416
- Testing
- QL1706 + Lenvatinib
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Sun Yat-sen University
Premature Ejaculation
Glans Penis Augmentation by Hyaluronic Acid for Treatment of Premature Ejaculation
This randomized controlled cross-over study aims to evaluate the effect and safety of glans penis augmentation using Hyaluronic acid in the treatment of premature ejaculation in compare with placebo .
- Trial name
- NCT03459833
- Testing
- Hyaluronic Acid
- Volunteers
- 30 people
- Sponsor
- Cairo University
Peyronie Disease
Novel Nanofat Regenerative Surgical Technique for Peyronies' Disease Treatment
Peyronies' disease (PD) is an acquired connective tissue disorder characterized with the growth of fibrous and/or calcified plaques in the tunica albuginea of the penis.
- Trial name
- IPPNANOFAT (NCT05316714)
- Testing
- Nanofat grafing
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- University of Roma La Sapienza
Sickle Cell Anemia, Priapism
Tadalafil for Treatment of Priapism in Men With Sickle Cell Anemia
This research is being done to compare the effect of tadalafil with placebo (an inactive substance that looks like the study drug, but should have no effect) on the frequency of recurrent priapism (prolonged erection…
- Trial name
- NCT00538564
- Testing
- tadalafil
- Where
- United States
- Sponsor
- Johns Hopkins University
Hernia Repair, Orchiopexy
Postoperative Pain Relief in Children: Comparing Caudal Bupivacaine Alone Versus Bupivacaine With Dexmedetomidine for Infra-Umbilical Surgeries Under General Anesthesia
This study is being done to find out which medicine combination provides better pain relief after surgery in children. Children who are having surgery below the belly button (called infra-umbilical surgery) will receive general…
- Conditions
- Hernia Repair, Orchiopexy, Hypospadias
- Trial name
- NCT07121764
- Testing
- Bupivacaine %0.25 (isobaric), Dexmedetomidine & Bupivacaine.
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Allama Iqbal Teaching Hospital
Peyronies Disease
Platelet-Rich Plasma for Peyronie's Disease
The purpose of this clinical trial is to evaluate the effects of Platelet-Rich Plasma (PRP) intralesional injections in men affected by Peyronie's disease (PD) in the fibrotic phase.
- Trial name
- NCT07117955
- Testing
- Autologous Platelet Rich Plasma, Saline solution
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- Herlev Hospital