Clinical trials: Pemphigus
Other Specified Inflammatory Disorders of Skin or Subcutaneous Tissue, Pyoderma Gangrenosum
Observational Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases
This study investigates the genetic architecture of Neutrophil-Mediated Inflammatory Skin Diseases. After collecting informed consent, all patients' clinical phenotype is graded at inclusion with a detailed case report form and a…
- Conditions
- Other Specified Inflammatory Disorders of Skin or Subcutaneous Tissue, Pyoderma Gangrenosum, Erosive Pustular Dermatosis of the Scalp, Sweet's Syndrome
- Trial name
- NEUTROGENE (NCT01952275)
- Testing
- Collection of biological samples
- Where
- Switzerland
- Volunteers
- 600 people
- Sponsor
- University of Zurich
Gingival Diseases, Gingivitis
Acquired Chronic Erosive Gingivitis: Clinical Relevance of Papillary Gingival Biopsy
Chronic erosive gingivitis is a syndrome (CEGS) that combines severe gingival inflammation and gingival erosion. The term "desquamative gingivitis" is often used in the literature to define chronic erosive gingivitis.
- Conditions
- Gingival Diseases, Gingivitis, Autoimmune Diseases, Oral Lichen Planus
- Trial name
- NCT04293718
- Testing
- papillary gum biopsies
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Oral Lesions in Patients With Pemphigus Vulgaris
Comparison of the Efficacy of Clobetasol Propionate 0.05% Mouthwash, Photobiomodulation, and Their Combination in Managing of Oral Lesions in Patient With Pemphigus Vulgaris.
Pemphigus vulgaris (PV) is a chronic, potentially life-threatening autoimmune mucocutaneous disorder that significantly impairs patients' quality of life.
- Trial name
- NCT07641725
- Testing
- Clobetasol propionate 0.05% Mouthwash, diode laser for photobiomodulation, clobetasol propionate 0.05% mouthwash + photobiomodulation
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Asthma
Promoting Risk Reduction Among Young Adults With Asthma During Wildfire Smoke Events (TRAK)
This research will contribute to fundamental knowledge about how young adults with asthma perceive their personal health risks to wildfire smoke, minimize their risk, and improve their health.
- Trial name
- TRAK (NCT04724733)
- Testing
- Smoke Sense, Smoke Sense Plus
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Washington State University
Oral Lichen Planus, Mucous Membrane Pemphigoid
Dexamethasone Solution and Dexamethasone in Mucolox™
Topical steroid therapy is considered the first line of treatment for Oral Inflammatory Ulcerative Diseases with current treatment regimens requiring multiple application or rinses daily.
- Conditions
- Oral Lichen Planus, Mucous Membrane Pemphigoid, Pemphigus Vulgaris, Chronic Graft-versus-host-disease
- Trial name
- NCT04540133
- Testing
- dexamethasone 0.5mg/5ml solution, dexamethasone 0.5mg/5ml solution in Mucolox™
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pemphigus
Hematopoietic Stem Cell Support in Patients With Autoimmune Bullous Skin Disorders
Autoimmune Bullous Skin Disorders are believed to be due to immune cells, cells that normally protect the body and are now causing damage to the body.
- Trial name
- NCT00278642
- Testing
- Hematopoietic stem cell transplantation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Richard Burt, MD
Pemphigus
A Single-center Study of CM313 in Patients With Pemphigus
A prospective, single-center, single-arm clinical study aimed to explore the efficacy and safety of the anti-CD38 monoclonal antibody CM313 combined with low-dose glucocorticoids in patients with pemphigus.
- Trial name
- NCT06904040
- Testing
- CM313 injection, glucocorticoids
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Sichuan Provincial People's Hospital
Pemphigus Vulgaris, Pemphigus Foliaceus
Phenotypic and Functional Characterisation of Human B-cell Response in Pemphigus
Pemphigus is a rare autoimmune disease involving skin and mucous membranes characterized by the production of pathogenic autoantibodies directed against desmosomal transmembrane glycoproteins belonging to the cadherin…
- Trial name
- CaReLyBP (NCT04117529)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pemphigus
Use of Infliximab for the Treatment of Pemphigus Vulgaris
Pemphigus vulgaris (PV) is a rare skin disorder that causes blistering of the skin and mucous membranes. Infliximab is a man-made antibody used to treat certain types of immune system disorders, including rheumatoid arthritis and…
- Trial name
- NCT00283712
- Testing
- Infliximab
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Bullous Pemphigoid
Comparison of Two Therapeutic Strategies of Dermoval in Treatment of Bullous Pemphigus
to compare efficacity and tolerance of two stratégies of dermoval application in treatment of bullous pemphigus.
- Trial name
- NCT00213421
- Testing
- Dermoval
- Where
- France
- Volunteers
- 330 people
- Sponsor
- University Hospital, Rouen