Clinical trials: Pediatrics
Human Microbiome, Pediatrics
Human Microbiome Research and Development for Overcoming Pediatric Diseases
Prediction and treatment of pediatric diseases and long-term outcomes through microbiome and multi-omics analysis by life cycle: We aim to demonstrate that a wide range of diseases are associated with gut microbiome dysbiosis and…
- Conditions
- Human Microbiome, Pediatrics, Disease, Growth & Development
- Trial name
- NCT06812091
- Where
- South Korea
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hanyang University
Overweight, Obesity
Impact of Active and Healthy Families
The purpose of this study is to evaluate the impact of the 10-week Active and Healthy Families (AHF) intervention on body mass index (BMI) in Latino youth aged 5-12 years.
- Trial name
- AHF (NCT02044705)
- Testing
- Active and Healthy Families
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Cardiopulmonary Arrest, Resuscitation
Augmented Reality to Support Cardiopulmonary Resuscitation
A prospective, multicenter, randomized clinical trial in two tertiary pediatric emergency department. It will assess, amongst pediatric healthcare teams, whether the use of augmented reality supportive devices improves adherence…
- Conditions
- Cardiopulmonary Arrest, Resuscitation, Pediatric
- Trial name
- NCT06376643
- Testing
- Augmented reality supportive tool, Conventional method (AHA pocket reference card)
- Where
- 2 sites in Canada, Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Johan Siebert, MD
Childhood Obesity
The SIM-PLICITY Study: The SIMulation Project - LIstening & Intervention in Pediatric obeSITY
This study is looking at the feasibility and efficacy of using SIMmersion's PeopleSim technology to train providers through role playing simulations to effectively conduct discussions with parents to provide intervention for, and…
- Trial name
- SIM-PLICITY (NCT02946515)
- Testing
- Educational Intervention, Wait List Control
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Pain
Effectiveness of Parent-Led Interventions in Reducing Infant Hypersensitivity to Pain
The aim of this study is to find out the effects of routinely using different types of pain-relieving strategies during routine immunization injections performed in infants.
- Trial name
- NCT01503060
- Testing
- Educational video - Active, Sucrose
- Where
- 2 sites in Canada
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
IGF-1 Deficiency
IGF-1, IGFBP3, ALS Normative Ranges in Healthy Pediatric Spanish Population
To determine the normative ranges of the Insulin-like Growth Factor 1 (IGF-1), Insulin-like growth factor-binding protein 3 (IGFBP-3), Acid-Labile Subunit (ALS) according to age, sex and pubertal stage of a healthy paediatric…
- Trial name
- EDISON (NCT01676090)
- Where
- 9 sites in Spain
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Ipsen
Pharmacokinetics
Study of Finerenone to Investigate a Paediatric Formulation in Healthy Male Subjects
Finerenone is developed for the treatment of diabetic kidney disease (adults) and chronic kidney disease (children). The purpose of the proposed trial is to test the pharmacokinetics of a novel liquid formulation for the…
- Trial name
- NCT02957396
- Testing
- Finerenone (BAY94-8862): 20 mg intact tablet, Finerenone (BAY94-8862): 20 mg crushed and resuspended tablet, Finerenone (BAY94-8862): 20 mg suspension
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Bayer
Heart; Surgery, Heart, Functional Disturbance as Result, Pediatric ALL
Oblique Versus Transverse Orientation Approach for Internal Jugular Venous Cannulation in Pediatrics
this study aimed to compare oblique versus transverse orientation approach in jugular venous cannulation in term of cannulation success in pediatric heart surgery patients
- Trial name
- NCT05656937
- Testing
- internal jugular venous cannulation
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Pain
Does the Order in Which Vaccines Are Administered Affect Pain Response?
The objective of this study is to determine whether there should be a predetermined sequence recommended for administering these two vaccines, with the less painful vaccine being given first.
- Trial name
- NCT00390130
- Testing
- Pentacel (DPTaP+Hib), Prevnar (conjugated pneumococcal vaccine)
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Constipation Chronic Idiopathic
Evaluation of the Triple Management Program in the Management of Functional Chronic Constipation in Children
Abstract Background: Chronic constipation is a common disease in children, 3% all children visit gastroenterology clinics with different types and complains.
- Trial name
- NCT06082622
- Testing
- laxatives
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Minia University
Emergence Agitation, Pain
Emergence Agitation and Pain Scores in Pediatrics When Comparing Single-modal vs Multi-modal Analgesia for ENT Surgery
The purpose of this study is to compare the incidence of EA in pediatric patients undergoing minor ENT surgery under Sevoflurane and compare opioid-only based intra-operative analgesia to multi-modal analgesia consisting of…
- Trial name
- NCT03062488
- Testing
- IV acetaminophen, Fentanyl, PO acetaminophen
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Inflammatory Bowel Diseases, Crohn Disease
PIBD-SETQuality: the Inception Cohort and Safety Registry
The purpose of this study is to analyse effectiveness and safety signals of current treatment strategies in routine practice for patients with pediatric-onset inflammatory bowel disease (PIBD) and to correlate this to their…
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
- Trial name
- PIBD-SETQ (NCT03571373)
- Testing
- No intervention
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Education, Nursing
Digital Storytelling in Pediatric Safe Drug
Summary Aim: This research was conducted to determine the effectiveness of education given to students using digital storytelling in safe pediatric intravenous drug administration.
- Conditions
- Education, Nursing, Innovativeness
- Trial name
- NCT05845957
- Testing
- Digital Education Group
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ege University
Diabetes, Pre-diabetes
Metformin at the Cellular Level and Dosing for Diabetes Mellitus (DM)
The investigators know that metformin works at the level of the cells in the body by acting on a protein called Cyclic amine monophosphate- Response Binding Elements (CREB) binding protein or Constitutive Reverter of eIF2α…
- Conditions
- Diabetes, Pre-diabetes, Obesity
- Trial name
- NCT01876992
- Testing
- Metformin
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hearing Impairment
Speech-Evoked Auditory Potentials: Multisite Pediatric Evaluation
The goal of this study is to evaluate the sensitivity of a newly-developed prototype device in its ability to measure brain responses to speech sounds in an infant population.
- Trial name
- SEFR (NCT07392164)
- Testing
- A newly developed prototype device for speech-evoked EFR Measurement
- Where
- 3 sites in Australia, Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Susan Scollie
Healthy, Obese
Reference Values of Aerobic Fitness in the Contemporary Paediatric Population
In most pediatric medical conditions, tremendous progress in pediatrics has significantly improved the overall prognosis and transferred the mortality from childhood to adulthood.
- Trial name
- SAIN&NORMES (NCT04876209)
- Where
- France
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Glaucoma, Suspect, Optic Nerve Hypoplasia and Abnormalities of the Central Nervous System
A More Engaging Visual Field Test to Increase Use and Reliability in Pediatrics
The majority of young children do not think that visual field (VF) testing of peripheral vision is similar to a game; therefore, it is not surprising that they have difficulty maintaining attention during VF testing and thus the…
- Conditions
- Glaucoma, Suspect, Optic Nerve Hypoplasia and Abnormalities of the Central Nervous System, Congenital Coloboma of the Optic Nerve, Optic Nerve Head Pits, Bilateral Congenital
- Trial name
- NCT02157025
- Testing
- Cartoon video fixation target and cartoon character voice audio instructions during Humphrey perimetry, Usual Care procedures during Humphrey perimetry for children
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Inflammatory Bowel Disease, Crohn's Disease
The Role of Gut Microbiome in Predicting Comorbidities and Complications in Children With Inflammatory Bowel Disease
Background: Bacteria and other microorganisms that live in the intestines (the gut microbiome) play an important role in a person s health. The gut microbiome helps to regulate the immune system and control inflammation.
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
- Trial name
- NCT05652491
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Asthma, Vitamin D Deficiency
Rapid vs Maintenance Vitamin D Supplementation in Deficient Children With Asthma to Prevent Exacerbations.
The role of vitamin D in respiratory health remains uncertain. Whether vitamin D reduces clinically important exacerbations of childhood asthma remains uncertain.
- Trial name
- NCT01395589
- Testing
- Vitamin D
- Where
- Qatar
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Pediatric Obesity
Primary Care Pediatrics Learning Activity and Nutrition With Families
This study is designed to translate an evidence-based family-based weight loss treatment for childhood obesity (FBT) into primary care settings using co-located interventionists to serve as a model for care delivered within a…
- Trial name
- PLAN (NCT02873715)
- Testing
- Family-based treatment, Usual Care
- Where
- 4 sites in United States
- Volunteers
- 1,010 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo