Clinical trials: Pediatric Intensive Care Unit
Acute Respiratory Failure
Study on Ventilation Distribution With Electrical Impedance Tomography for Paediatric Respiratory Failure
Electrical impedance tomography (EIT) is a non-invasive, bedside monitoring technique that provides continuous, real-time information about the regional distribution of the ventilation.
- Trial name
- PELUCHE1 (NCT05347563)
- Testing
- Electrical impedance tomography
- Where
- 4 sites in France
- Volunteers
- 250 people
- Sponsor
- Hospices Civils de Lyon
Acute Kidney Injury, Renal Replacement Therapy
FST Analysis Supporting Timely Therapy and Risk Assessment Via Clinical Decision Support for Kids
The goal of this study is to learn whether adding a clinical decision support tool to the electronic medical record helps clinicians use the furosemide stress test in critically ill children at high risk for severe acute kidney…
- Conditions
- Acute Kidney Injury, Renal Replacement Therapy, Pediatric Intensive Care Unit
- Trial name
- FAST TRACK (NCT07718464)
- Testing
- Furosemide Stress Test Clinical Decision Support Tool
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Physical Functional Impairment, Cognitive Impairment
PICS-p Longitudinal Cohort Study
Children who survive critical illness may develop new or worsening problems with physical health, cognitive status, emotional well-being, and social functioning.
- Conditions
- Physical Functional Impairment, Cognitive Impairment, Psychological Distress, Impaired Social Functioning
- Trial name
- PICSpLCS (NCT07876271)
- Volunteers
- 200 people
- Sponsor
- Children's Hospital of Fudan University
Nurse-Patient Relations
Stress and Satisfaction Levels of Mothers According to Neuman's Systems Model on Stress and Satisfaction Levels of Mothers With Children in the Intensive Care Unit and Effective Decision Making
Research; It will be carried out to examine the effect of the empowerment program structured according to the Neuman systems model on the stress and satisfaction levels and effective decision-making of mothers whose children are…
- Trial name
- NCT06429592
- Testing
- education
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Intensive Care Pediatric
Corticosteroids Before Extubation in Pediatric Intensive Care Unit
Fifty to 60% of children admitted to a pediatric intensive care unit (PICU) are placed under invasive mechanical ventilation (MV) at least once during their stay.
- Trial name
- COBEX-PED (NCT06722118)
- Testing
- Dexamethasone IV
- Where
- 15 sites in France
- Volunteers
- 348 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pediatric Acute Neurologic Disease, Traumatic and Non-traumatic
RCT: Early Rehabilitation Protocol vs. Usual Care in the Pediatric ICU for Children With Acute Brain Injury
Background. Early rehabilitation programs (ERP) that include physical, occupational, and speech therapies lessens debilitation and promotes return to previous physical and cognitive functioning and have been successfully applied…
- Trial name
- NCT02209935
- Testing
- Early Rehabilitation Protocol, Usual care
- Where
- 3 sites in United States
- Volunteers
- 58 people
- Sponsor
- University of Pittsburgh
Fever
Fever Observational Study
To inform the feasibility of conducting a study to test different temperature thresholds at which clinicians deliver interventions to reduce fever (i.e.
- Trial name
- NCT03028818
- Where
- United Kingdom
- Volunteers
- 3,960 people
- Sponsor
- Intensive Care National Audit & Research Centre
Cardio-Respiratory Distress
Early Mobilization: Evaluation of Feasibility and Security in Pediatric Intensive Care Unit
The purpose of this study is to evaluate the feasibility and the security of early mobilization of infants in pediatric intensive care.
- Trial name
- NCT02958124
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Intensive Care Units, Pediatric
Therapeutic Follow-up of Antibiotics in Pediatric Intensive Care
Currently, recommendations for antibiotic testing (ATS) in adult intensive care have been published. The 2018 SFAR and the Abdul- Aziz et al expert conference recommend routine testing for β-lactams, aminoglycosides, linezolid…
- Trial name
- STAR-P (NCT05354635)
- Testing
- Antibiotics Dosing
- Where
- Reunion
- Volunteers
- 280 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Critical Illness
Music Intervention for Agitation Reduction in the Pediatric Intensive Care Unit
The objective of this study is to administer music therapy to patients in the pediatric intensive care unit (PICU) in order to observe how music affects patient agitation, vital signs, and overall recovery in the unit.
- Trial name
- NCT03453814
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- State University of New York at Buffalo
Mechanical Ventilation Complication, Enteral Feeding Intolerance
Gastric Ultrasound to Monitor Gastric Residual Volume
It is currently recommended to start enteral nutrition early in intensive care unit children receiving invasive or non-invasive mechanical ventilation.
- Trial name
- GASTRIPED (NCT04119089)
- Testing
- Gastric ultrasound
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Hospices Civils de Lyon
Hypertension
Sodium Nitroprusside for Blood Pressure Reduction in the ICU (SNP2)
Nitroprusside is used commonly in the Intensive Care Unit for long periods of time in order to reduce blood pressure. It is not known if the body compensates over time to the blood pressure lowering, and if when the nitroprusside…
- Trial name
- NCT00621816
- Testing
- nitroprusside
- Where
- 8 sites in United States
- Volunteers
- 45 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Acute Kidney Injury, Renal Replacement Therapy
Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric AKI
This study follows a group of patients admitted to the PICU who are identified as being at risk for developing acute kidney injury.
- Conditions
- Acute Kidney Injury, Renal Replacement Therapy, Pediatric Intensive Care Units
- Trial name
- Taking Focus 2 (NCT03541785)
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Acute Respiratory Distress Syndrome, Pediatric Intensive Care Unit
Pediatric Acute Respiratory Distress Syndrome Asia Study
Mortality rates in children with pediatric acute respiratory distress syndrome (PARDS) are higher in Asia compared to other regions.
- Conditions
- Acute Respiratory Distress Syndrome, Pediatric Intensive Care Unit, Mechanical Ventilation
- Trial name
- PARDS Asia (NCT04068038)
- Testing
- Ventilation protocol
- Where
- 19 sites in China, Hong Kong and 8 more
- Volunteers
- 738 people
- Sponsor
- KK Women's and Children's Hospital
Vital Signs
Validation of Continuous Monitoring of Vital Signs in Children With a Connected Patch
Small connected devices monitoring vital signs do not exist in children although they could be very useful to monitor patients once they have left the pediatric intensive care unit (PICU) in order to early identify patients at…
- Trial name
- VITALPICU (NCT04627766)
- Testing
- Monitoring with VT-Patch (Connected device manufactured by VitalTracer)
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- St. Justine's Hospital
Urinary Tract Infections
Decreasing Catheter-Associated Urinary Tract Infections in the Pediatric Intensive Care Unit
The purpose of this study is to identify risk factors associated with indwelling urinary catheters, as well as to assess the nurses' knowledge and adherence to hospital policies.
- Trial name
- NCT00672503
- Where
- United States
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Bronchiolitis
Intrapulmonary Percussive Ventilation for Children With Bronchiolitis on Non-Invasive Ventilation Support
Prospective randomized study of patients admitted to the Pediatric Intensive Care Unit suffering from Bronchiolitis and are supported on Non Invasive Positive Pressure Ventilation.
- Trial name
- NCT03037801
- Testing
- Intrapulmonary Percussive Ventilation (Percussionaire Corp, Sandpoint, Idaho)
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Soroka University Medical Center
Neonatal Nursing, Transportation of Patients
Safe Transport Algorithm and TRIPS in Neonatal Transport
Aim: Newborn babies may need to be referred to different centers to receive the care they need. It is important to improve the quality of neonatal transport to reduce infant mortality rates.
- Conditions
- Neonatal Nursing, Transportation of Patients, Newborn
- Trial name
- TRIPS (NCT07379619)
- Testing
- As part of the intervention, a 10-step safe transport algorithm developed by researchers and validated by expert opinion, along with TRIPS, was displayed in clinical areas, and verbal training was pro
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beste Ozguven Oztornaci
Non-convulsive Seizures
Detecting Non-convulsive Seizures in the Paediatric Intensive Care Unit
The objective of this study is to determine if paediatric intensive care nurses and physicians can identify non-convulsive seizures in critically ill children using quantitative electroencephalography (EEG), in real time at the…
- Trial name
- NCT03856775
- Testing
- Quantitative EEG and Seizure detector
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- McMaster University
Laughter Yoga
Effects of Laughter Yoga in Mothers of PICU Patients
This randomized controlled trial examined the effects of laughter yoga on resilience and coping attitudes in mothers of children hospitalized in the pediatric intensive care unit.
- Trial name
- NCT07340229
- Testing
- Laughter Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University