Clinical trials: Pediatric Intensive Care
Communication, Critical Illness
Improving Family Meetings in the Pediatric Cardiac Intensive Care Unit
This study aims to improve communication between medical teams, patients, and families in the pediatric cardiac intensive care unit.
- Trial name
- NCT03749330
- Testing
- CICU Team And Loved Ones Communicating (CICU TALC)
- Where
- United States
- Volunteers
- 451 people
- Sponsor
- Children's Hospital of Philadelphia
Evaluate the Accuracy of the Masimo Radical 7 Hemoglobin Noninvasive Monitor
Validity of Radical 7 Masimo Monitor at Measuring Hemoglobin in Pediatric Cardiac Intensive Care
Fifty percent of children that survive a critical illness are anemic at discharge from the pediatric intensive care unit (PICU)(1).
- Trial name
- NCT03977142
- Testing
- Radical 7 Masimo Hemoglobin pulse co-oximeter non invasive monitor
- Volunteers
- 25 people
- Sponsor
- St. Justine's Hospital
Respiratory Distress, Upper Airway Obstruction
Air Leak Test In Pediatric Intensive Care Unit
Respiratory distress by upper airway obstruction (UAO) is the primary etiology of extubation failure in children hospitalized in pediatric intensive care unit (PICU).
- Trial name
- ALTIPICU (NCT05328206)
- Testing
- Standard of care for intubated children
- Where
- 19 sites in France
- Volunteers
- 900 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lung Injury, Extravascular Lung Water
Lung Ultrasound Score and Pediatric Intensive Care Outcomes (LUS-PICO)
Bedside lung ultrasonography helps to obtain reliable clinical information about lung aeration, that has been categorized by means of the so-called lung ultrasound score (LUS).
- Conditions
- Lung Injury, Extravascular Lung Water, Pulmonary Edema, Acute Respiratory Distress Syndrome
- Trial name
- LUS-PICO (NCT04660448)
- Testing
- Bedside lung ultrasound examination
- Where
- Spain
- Volunteers
- 650 people
- Sponsor
- Fundación para la Investigación Biosanitaria del Principado de Asturias
Respiratory Failure
Closed-loop FiO2 Controller During High Flow Oxygen Treatment In Pediatric Patients (COFICOHFOT)
Recently, high flow oxygen therapy (HFOT) is becoming more popular in the treatment of any kind of respiratory failure. Pediatric mechanical ventilation consensus conference (PEMVECC) guidelines suggest measuring oxygen…
- Trial name
- COFICOHFOT (NCT05032365)
- Testing
- Close-loop FiO2 controller, Conventional
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Mechanical Ventilation, Sedation
Implementation of an Analgesia-sedation Algorithm in the Pediatric ICU to Reduce Benzodiazepine Use
The purpose of the study is to develop and implement an evidence-based analgesia-sedation algorithm in the pediatric intensive care unit (PICU) using quality improvement and implementation science methodology.
- Trial name
- NCT04263662
- Testing
- Analgesia-Sedation algorithm
- Where
- United States
- Volunteers
- 680 people
- Sponsor
- Boston Children's Hospital
Critically Ill, Hyperglycemia
Improving Blood Glucose Control With a Computerized Decision Support Tool: Phase 2
The Purpose of this study is to: 1. Introduce the refined, validated, and safe computerized bedside decision support tool for blood glucose management in critically ill adult and pediatric ICU patients that was studied in Phase 1…
- Trial name
- NCT00654797
- Testing
- glucose control with computer generated recommendations
- Where
- 10 sites in United States
- Volunteers
- 200 people
- Sponsor
- Intermountain Health Care, Inc.
Bacterial Infections
Compliance With AntibIotic TherapY Guidelines in French PICUs
This observational, prospective, multicenter study, conducted in nine French Pediatric and Neonatal Intensive Care Units (ICUs), will assess the antibiotic therapy for a child hospitalized in ICU and receiving systemic…
- Trial name
- COMITY (NCT04642560)
- Where
- France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Toulouse
Pediatric Intensive Care
Pupillometry in Pediatric Intensive Care Unit (PICU)
Assess the depth of sedation and analgesia in pediatric intensive care is critical to the management of intubated patients under mechanical ventilation. The responsiveness of the pupil is changed by the sedation and analgesia.
- Trial name
- Pupillomètre (NCT02847195)
- Testing
- pupillometry
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Hospices Civils de Lyon
Mechanical Ventilation
Evaluation of the Patient-ventilator Asynchrony During Mechanical Ventilation for Pediatric Acute Respiratory Failure
The synchronization between the patient and the ventilator is an essential objective during mechanical ventilation (MV). Maintaining the patient's respiratory activity during MV reduces ventilation pressures, improves…
- Trial name
- Asynchrony (NCT03138148)
- Testing
- Routine mechanical ventilation
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- St. Justine's Hospital
Circadian Dysregulation, Light Exposure
Feasibility of Light Therapy in the Pediatric Intensive Care Unit (ICU)
The goal of this clinical trial is to understand how easy or difficult it is for critically ill children (4-17 years old) to have light therapy while in the pediatric ICU.
- Conditions
- Circadian Dysregulation, Light Exposure, Pediatric Critical Illness
- Trial name
- NCT07384585
- Testing
- Light Therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Laura Beth Kalvas
Enteral Feeding Intolerance
Amoxicillin for Enteral Nutrition Intolerance in Pediatric Intensive Care Unit
The goal of this randomized controlled study is to investigate the efficacy of enteral amoxicillin for the treatment of children with feeding intolerance in pediatric intensive care unit.
- Trial name
- AmoxENI (NCT05828758)
- Testing
- Amoxicillin
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Sohag University
Intrusion Symptom
Remote Delivery of a Visuospatial Intervention to Reduce Traumatic Intrusive Memories After Paediatric Intensive Care
This study aims to examine the feasibility and acceptability of a brief intervention, involving a imagery-competing task, remotely delivered to parents who are currently experiencing persistent intrusive traumatic memories at…
- Trial name
- NCT05500105
- Testing
- Simple cognitive task intervention
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Prolonged Mechanical Ventilation in Pediatric Intensive Care Unit
LongVentKids Study
Scientific advances, population growth, lower mortality, and increasing complexity of diseases have boosted up the number of patients requiring prolonged breathing assistance with mechanical ventilators in the pediatric intensive…
- Trial name
- LVK (NCT04112459)
- Testing
- prolonged mechanical ventilation
- Where
- Canada
- Volunteers
- 6,000 people
- Sponsor
- St. Justine's Hospital
Acute Respiratory Failure
Evaluation of Perfusion and Ventilation Distribution in Children: a Pilot Study.
Electrical impedance tomography (EIT) is a recent monitoring technique that provides information on regional ventilation distribution.
- Trial name
- PELUCHE 2 (NCT07532811)
- Testing
- Evaluation of perfusion with Electrical impedance tomography using sodium chloride or sodium bicarbonate
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Covid19, Burnout, Professional
Mental Health of Professionals Working in Pediatric Intensive Care Units During the COVID-19 Pandemic
Health professionals are extremely exposed to psychosocial risks, as they experience, in general, high levels of stress, anxiety, fatigue and suffering, due to the nature and location of their work.
- Conditions
- Covid19, Burnout, Professional, Stress Disorders, Post-Traumatic, Anxiety
- Trial name
- NCT04846907
- Testing
- Web-based survey
- Where
- Brazil
- Volunteers
- 1,148 people, healthy volunteers welcome
- Sponsor
- D'Or Institute for Research and Education
Rhabdomyolysis
Pediatric Rhabdomyolysis in the Pediatric Intensive Care Unit: A Retrospective Cohort Study
This retrospective observational cohort study aims to evaluate the clinical characteristics, causes, intensive care management, and outcomes of pediatric patients with rhabdomyolysis admitted to the Pediatric Intensive Care Unit…
- Trial name
- NCT07851987
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- Hannover Medical School
Critical Illness, Enteral Feeding Intolerance
Evaluation of Enteral Nutrition in Critically Ill Children
The aim of this study was to evaluate the effect of calorie and enteral feeding timing on survival in critically ill children receiving inotropic, vasopressor and inodilatory supplements.
- Trial name
- NCT04013893
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Cukurova University
Critical Illness
Music Intervention for Agitation Reduction in the Pediatric Intensive Care Unit
The objective of this study is to administer music therapy to patients in the pediatric intensive care unit (PICU) in order to observe how music affects patient agitation, vital signs, and overall recovery in the unit.
- Trial name
- NCT03453814
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- State University of New York at Buffalo
Critical Illness Polyneuropathy
Evaluation of Pediatric Critical Illness Neuropathy/Myopathy in Pediatric Intensive Care Unit
Intensive Care Unit Acquired Weakness(ICUAW) encompasses a spectrum of disorders characterized by generalized weakness developing after the onset of critical illness.
- Trial name
- NCT02763709
- Where
- India
- Volunteers
- 97 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh