Clinical trials: Pediatric Imaging
TBI (Traumatic Brain Injury)
MR Imaging Study of TBI in Children
This project will combine the data collected from structural and functional MRI scans and neuropsychology performance post-TBI in children.
- Trial name
- MISTIC (NCT03034031)
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Congenital Heart Disease
4-D Visualization Using Magnetic Resonance Imaging (MRI) in the Congenital Heart Disease Population
In this study, the investigators wish to use images obtained from standard of care cardiac MRI's performed at Children's Healthcare of Atlanta and transfer the images to a different computer in order to analyze them with a new…
- Trial name
- NCT00165945
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Emory University
Leukemia
Ultrasound Use for Difficult Lumbar Punctures in Pediatric Oncology Patients
Hematology-oncology patients may require frequent lumbar puncture for diagnosis, assessment and therapy. When LP is difficult, the patient may endure multiple attempts, prolonged anesthesia time, and with failure of LP may…
- Trial name
- NCT01643291
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Nationwide Children's Hospital
Thrombosis
Pediatric Catheter-related Thrombosis Imaging Study
This protocol will serve as a pilot study to determine the validity and feasibility of contrast enhanced magnetic resonance imaging (MRI) without and with contrast and/or ultrasound (US) for detection of catheter related deep…
- Trial name
- AESOP (NCT01137578)
- Testing
- Ultrasound, Magnetic Resonance Imaging with Contrast, Magnetic Resonance Imaging without Contrast
- Where
- 26 sites in United States, Argentina and 7 more
- Volunteers
- 151 people
- Sponsor
- Bristol-Myers Squibb
Brain Damage, Chronic, Cerebellar Cognitive Affective Syndrome
DTI & Tractography in Pediatric Tumor Surgery
The goal of this project will be to demonstrate that Synaptive Medical's Diffusion Tensor Imaging(DTI) product functionality used in pre-operative planning and intraoperative surgical navigation, improves clinical outcomes…
- Conditions
- Brain Damage, Chronic, Cerebellar Cognitive Affective Syndrome, Cerebellar Mutism
- Trial name
- NCT02810626
- Testing
- BrightMatter™ products
- Volunteers
- 24 people
- Sponsor
- London Health Sciences Centre
Posterior Brain Fossa Tumors in Children
Feasibility of 11C-MET PET/MRI Imaging in Pediatric Brain Fossa Tumors
Brain tumors are the most common solid tumors in children and are the second most common cause of cancer-related death among this population. Posterior brain fossa tumors represent about 50% of children brain tumors.
- Trial name
- TI-TFCE (NCT03977896)
- Testing
- 11C-MET PET/MRI
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Hospices Civils de Lyon
Childhood Brain Neoplasm, Recurrent Childhood Brain Neoplasm
DSC-MRI With Ferumoxytol and DCE-MRI With Gadolinium in Imaging Vascular Properties in Younger Patients With Brain Tumors
This clinical trial studies dynamic susceptibility-weighted contrast enhanced magnetic resonance imaging (DSC-MRI) after administration of ferumoxytol and dynamic contrast-enhanced MRI (DCE-MRI) after administration of a…
- Trial name
- NCT00978562
- Testing
- Dynamic Contrast-Enhanced Magnetic Resonance Imaging, Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging, Ferumoxytol Non-Stoichiometric Magnetite
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- OHSU Knight Cancer Institute
Brain Tumors
Comparison of PET and Proton MRS Imaging to Evaluate Pediatric Brain Tumor Activity
This study in children and young adults will compare two types of imaging, positron emission tomography ([(18)F]-DG PET) and proton magnetic resonance spectroscopy ((1)H-MRSI), to determine activity of a brain tumor or abnormal…
- Trial name
- NCT00067821
- Testing
- 2-Flourodeoxyglucose
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- National Cancer Institute (NCI)
Myocarditis
Cardiovascular Imaging in Pediatric Myocarditis
This study aims to utilize cardiac magnetic resonance (CMR) to assist in the clinical diagnosis, conduct consecutive assessments for myocardial tissue in pediatrics with myocarditis, and explore effective predictive factors for…
- Trial name
- NCT06652399
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- West China Second University Hospital
Brain Tumor
Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures
The objective of the study is to assess safety of panitumumab-IRDye800 in pediatric patients undergoing brain surgery to remove suspected tumors.
- Trial name
- NCT04085887
- Testing
- Panitumumab-IRDye800, Pinpoint-IR9000 endoscopic/handheld device, Explorer Air camera
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Obsessive-Compulsive Disorder
Characterization of Childhood-Onset Obsessive-Compulsive Disorder
The purpose of this study is to learn more about Obsessive-compulsive Disorder (OCD) in children. OCD usually has a slow onset, and symptoms that may remain at a stable level over time.
- Trial name
- NCT00044239
- Where
- 4 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Autosomal Recessive Polycystic Kidney Disease
Imaging Assessments of ARPKD Kidney Disease Progression
Autosomal Recessive Polycystic Kidney Disease (ARPKD) is a potentially lethal genetic disorder for which there are currently no disease specific treatments.
- Trial name
- IMAGE-ARPKD (NCT07201025)
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Childhood Obesity
Magnetic Resonance Imaging Assessment of Multiorgan Health in Obesity
The goal of this study is to quantify the body composition and organ fat distribution changes with obesity interventions in adolescents with severe obesity.
- Trial name
- FIT-YOUNG (NCT07702825)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Alder Hey Children's NHS Foundation Trust
Cardiac Arrest
Prognostication Biomarkers in Pediatric Cardiac Arrest
This multicenter study will validate a panel of serum, imaging, and clinical biomarkers to classify patient outcome early after out-of-hospital pediatric cardiac arrest.
- Trial name
- NCT02769026
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- University of Pittsburgh
Epilepsy, Temporal Lobe
A Deep Learning Framework for Pediatric TLE Detection Using 18F-FDG-PET Imaging
This study aims to use radiomics analysis and deep learning approaches for seizure focus detection in pediatric patients with temporal lobe epilepsy (TLE).
- Trial name
- NCT04169581
- Where
- China
- Volunteers
- 201 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pediatric Low-grade Gliomas
Developing Fast Pediatric Imaging
This research study is evaluating the investigational software for magnetic resonance imaging (MRI) systems and techniques to process magnetic resonance (MR) images
- Trial name
- NCT03761121
- Testing
- Wave-CAIPI
- Where
- 3 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Glymphatic System, White Matter Disease
Evaluation of Brain Waste Clearance Pathways Using Magnetic Resonance Imaging in Pediatric Patients With White Matter Diseases
The dilation of perivascular spaces can be the result of various etiopathogenetic processes. White matter atrophy can cause enlargement of these perivascular spaces (PVS) but also obstruction of fluid drainage systems…
- Conditions
- Glymphatic System, White Matter Disease, Pediatric Disorder, Perivascular Disease
- Trial name
- NCT06335004
- Testing
- Magnetic resonance imaging
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Eugenio Medea
Pediatric Central Nervous System Tumor
Study of Tozuleristide and the Canvas Imaging System in Pediatric Subjects With CNS Tumors Undergoing Surgery
Many types of cancer are primarily treated with surgery and patient survival is directly related to the extent to which the tumor is able to be removed.
- Trial name
- NCT03579602
- Testing
- tozuleristide, Canvas System
- Where
- 9 sites in United States
- Volunteers
- 118 people
- Sponsor
- Blaze Bioscience Inc.
Bone Fractures
Ultrasound Assessment of Pediatric Fracture Healing With the PLUS Score
This observational study investigates whether ultrasound can safely and accurately monitor the healing of bone fractures in children, comparing it to standard X-rays.
- Trial name
- USG-FRACTHEAL (NCT07755787)
- Testing
- Point-of-care ultrasound
- Where
- Czechia
- Volunteers
- 1,200 people
- Sponsor
- University Hospital Hradec Kralove
Cystic Fibrosis
18FDG-PET Imaging to Detect Changes in Airways Inflammation in Cystic Fibrosis Patients
The purpose of this study is to determine if 18Fluorodeoxyglucose (FDG) Positron Emission Tomography (PET) imaging can detect changes in airways inflammation in Cystic Fibrosis (CF) patients after treatment for a pulmonary…
- Trial name
- NCT00684346
- Testing
- 18-FDG
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- The Hospital for Sick Children