Clinical trials: Patient-controlled Analgesia
Acute Postoperative Pain
Postoperative Pain Therapy With Hydromorphone TCI-PCA vs. Morphine PCA
Treatment of postoperative pain with hydromorphone (a strong analgesic) using patient-controlled analgesia with target-controlled infusion compared to conventional patient-controlled analgesia with morphine after elective cardiac…
- Trial name
- NCT02483221
- Testing
- Hydromorphone, Morphine
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Hip Fractures, Supra-inguinal Fascia Iliaca Block
Preoperative Supra-inguinal Fascia Iliaca Block for Positioning Analgesia in Hip Fracture Patients Undergoing Spinal Anesthesia
The goal of the clinical trial is to learn if preoperative Superficial Inguinal Fascia Iliaca (SIFI) block works to reduce pain during positioning for spinal anesthesia.
- Conditions
- Hip Fractures, Supra-inguinal Fascia Iliaca Block, Spinal Anesthesia
- Trial name
- NCT07556614
- Testing
- Isobaric bupivacaine 0.5%
- Where
- Pakistan
- Volunteers
- 132 people
- Sponsor
- Ghurki Trust and Teaching Hospital
Diabetes Mellitus, Diabetic Neuropathy
Effects of Ankle Block on Postoperative Analgesia in Diabetic and Non-Diabetic Patients
This prospective observational study aims to evaluate the effects of ultrasound-guided ankle block on sensory and motor block characteristics and postoperative analgesic outcomes in patients undergoing lower extremity surgery.
- Conditions
- Diabetes Mellitus, Diabetic Neuropathy, Postoperative Pain Management
- Trial name
- ANKLE-DM (NCT07404124)
- Testing
- Ultrasound-Guided Ankle Block
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Hip Fracture
A Comparison of Two Pain Control Techniques on Deliruim in Hip Fracture Patients
The purpose of this study is compare the rates of post-operative delirium between a group of people receiving intravenous (IV) pain control after hip fracture surgery and a group of people receiving a femoral nerve catheter for…
- Trial name
- NCT01547468
- Testing
- Femoral Nerve Catheterization, Intravenous Opioids
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Leslie Thomas
İnguinal Hernia, Post Operative Pain
Comparison of QLB and TFP Block for Postoperative Analgesia in Laparoscopic Inguinal Hernia
This randomized controlled trial aims to compare the effects of ultrasound-guided lateral Quadratus Lumborum Block (QLB) and Transversalis Fascia Plane (TFP) block on postoperative analgesia in patients undergoing laparoscopic…
- Trial name
- NCT07604259
- Testing
- Lateral Quadratus Lumborum Block, Transversalis Fascia Plane Block, Port Site Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Medipol University
Non-Pharmacological Interventions, Breathing Exercise
Effect Of Game-Based Breathing Exercise On Pain, Fear, And Anxiety In Children During Venipuncture
Venipuncture is one of the most common invasive procedures in children and is often associated with significant pain, fear, and anxiety.This randomized controlled study will aim to evaluate the effects of a video game-based…
- Conditions
- Non-Pharmacological Interventions, Breathing Exercise, Venipuncture Pain, Pain Management
- Trial name
- NCT07550062
- Testing
- Intervention Group (Video Game-Based Breathing Exercise During Venipuncture), Video Game-Based Breathing Exercise Device
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uludag University
Knee Replacement, Postoperative Pain
Opioid-Sparing Protocol Comparing With Opioid-based Protocol After Bilateral Total Knee Arthroplasty
The concern for the opioid use in the total knee arthroplasty continues to rise in recent decades. Historically, the total knee arthroplasty consumed high doses opioids in the postoperative periods.
- Conditions
- Knee Replacement, Postoperative Pain, Opioid Use
- Trial name
- NCT04314505
- Testing
- Opioid-Sparing Protocol, Opioid-Based Patient Controlled Analgesia
- Where
- Taiwan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Rib Fractures
Randomized Clinical Trial of Rib Fixation Versus Medical Analgesia in Uncomplicated Rib Fractures on Pain Control.
Uncomplicated costal fractures often result in persistent pain over the long term. Indeed, cohort studies showed that at 6 months, 22% of patients still had pain and 56% had functional disability.
- Trial name
- PAROS (NCT04745520)
- Testing
- Rib fixation, Analgesia
- Where
- Switzerland
- Volunteers
- 102 people
- Sponsor
- Benoît Bédat
Post-cesarean Pain Control Quality
Comparisons Between Low Thoracic and Lumbar Epidural Analgesia on Postoperative Pain Low Thoracic v.s. Lumbar Epidural for Post-cesarean Pain
Whether low thoracic epidural analgesia improves postoperative cesarean pain qualities than conventional lumbar epidural analgesia?
- Trial name
- NCT03946982
- Testing
- low thoracic epidural, lumbar epidural
- Where
- Taiwan
- Volunteers
- 189 people
- Sponsor
- National Taiwan University Hospital
Postoperative Pain
ESP Versus SPSIP Block for Pain Relief After Shoulder Arthroscopy
This study will compare two regional anesthesia techniques for pain relief after arthroscopic shoulder surgery: high thoracic erector spinae plane (ESP) block and serratus posterior superior intercostal plane (SPSIP) block.
- Trial name
- ESP-SPSIP (NCT07906392)
- Testing
- High Thoracic Erector Spinae Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ferit Yetik
Rib Fractures, Acute Pain
Comparison of Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine in Ultrasound-Guided Erector Spinae Plane Block for Acute Pain Management in Patients With Traumatic Rib Fractures
Traumatic rib fractures cause severe chest wall pain that can impair normal breathing, coughing, and lung function. While systemic opioids are commonly used to treat traumatic pain, their side effects, such as sedation and…
- Conditions
- Rib Fractures, Acute Pain, Thoracic Trauma
- Trial name
- NCT07827157
- Testing
- Dexmedetomidine with Bupivacaine in ESPB, Dexamethasone with Bupivacaine in ESPB
- Volunteers
- 100 people
- Sponsor
- Assiut University
Pain, Postoperative
Dose Response Study of Dexmedetomidine in Orthopaedic Spine Surgery Patients
To study the multimodal protocol combining adjunct dexmedetomidine with oxycodone in intravenous patient-controlled analgesia bolus dosing and effects in patients scheduled for posterolateral lumbar spine fusion with bilateral…
- Trial name
- DoserespDex (NCT02454881)
- Testing
- Dexmedetomidine, Oxycodone
- Where
- Finland
- Volunteers
- 107 people
- Sponsor
- Turku University Hospital
Critical Illness, Pain
Treatment of Procedural Pain Associated With Turning in Patients With Mechanical Ventilation
Background: Few studies have addressed the situation of procedural pain and the use of preemptive analgesia for turning in patients under mechanical ventilation.
- Trial name
- NCT01950000
- Testing
- Fentanyl
- Where
- Spain
- Volunteers
- 75 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Cardiac Surgery, Adult
Erector Spinae Plane Block and Pain Management in Cardiac Surgery
Evaluation of the benefit effects of Peri-Operative analgesia by Continuous Bilateral Erector Spinae Plane block(ESP) for Open Cardiac Surgery: A case series prospective study with a comparison a retrospective case series (Before…
- Trial name
- ESPCATHEART (NCT03541837)
- Testing
- Ropivacaine
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- Vinmec Healthcare System
Postoperative Pain Management
Dexmedetomidine-Enhanced PCIA After Lobectomy in Nicotine-Dependent Patients
This randomized, double-blind, controlled clinical trial evaluates whether adding dexmedetomidine to an oliceridine-based patient-controlled intravenous analgesia (PCIA) regimen can improve postoperative pain control and…
- Trial name
- DEX-PCIA (NCT07306702)
- Testing
- Oliceridine, Dexmedetomidine
- Where
- China
- Sponsor
- Shenyang Sixth People's Hospital
Pain
A Prospective Safety Surveillance Study of Fentanyl Iontophoretic Transdermal System (40 Mcg)
The purpose of the study is to document the use of fentanyl HCl 40 mcg system under routine conditions and obtain a more comprehensive understanding of the safety of the system and complications that may not be spontaneously…
- Trial name
- NCT00665522
- Testing
- IV PCA with standard of care opioid analgesia
- Where
- 26 sites in Austria, Finland and 2 more
- Volunteers
- 218 people
- Sponsor
- Alza Corporation, DE, USA
Laparoscopic Surgery, Visceral Pain, Postoperative
Anrikefon-based Patient-controlled Intravenous Analgesia Following Laparoscopic Surgery
Visceral pain following laparoscopic surgery is frequently underestimated, yet it is associated with a range of adverse outcomes.
- Conditions
- Laparoscopic Surgery, Visceral Pain, Postoperative, Anrikefon, Patient-controlled Intravenous Analgesia
- Trial name
- NCT07525986
- Testing
- High-dose anrikefon, Medium-dose anrikefon, Low-dose anrikefon
- Where
- 4 sites in China
- Volunteers
- 140 people
- Sponsor
- Peking University First Hospital
Modified Radical Mastectomy
Adding Magnesium Sulfate to Combined Pecto-Intercostal & Serratus Anterior Planes Block on Post-operative Analgesia in Patients Undergoing Modified Radical Mastectomy
Here, in our study, we intend to compare the analgesic efficacy of magnesium sulfate as an adjuvant to local anesthetics added to the Pecto-Intercostal Fascial Block (PIFB) vs the Serratus Anterior Plane Block (SAPB) in patients…
- Trial name
- Mastectomy (NCT07434232)
- Testing
- combined Pecto-Intercostal- Serratus anterior fascial planes Block
- Volunteers
- 100 people
- Sponsor
- South Egypt Cancer Institute
Coronary Artery Bypass Graft (CABG), Effects of Emotional Freedom Techniques (EFT)
Effects of Emotional Freedom Techniques on Pain, Cardiac Anxiety, and Sleep Quality in Coronary Artery Bypass Grafting
Objective: To determine the effect of Emotional Freedom Techniques (EFT) on pain, cardiac anxiety and sleep quality in patients undergoing Coronary Artery Bypass Graft (CABG) surgery.
- Trial name
- NCT07120932
- Testing
- Effects of Emotional Freedom Techniques (EFT)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Hatice Balcı
Opioid Use, Injury Traumatic
A Pain and Coordination Plan for Reduced Opioid Use After Accidental Injuries
This clinical trial aims to lower the number of people who use opioids and improve the quality of health in patients who have experienced accidental injury by implementing a Pain and Coordination Plan (PAC-plan).
- Conditions
- Opioid Use, Injury Traumatic, Pain, Postoperative
- Trial name
- PAC-plan (NCT06055205)
- Testing
- PAC-plan
- Where
- Norway
- Volunteers
- 271 people
- Sponsor
- University of Oslo
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