Clinical trials: Patient-Controlled Analgesia
Analgesia, Postoperative Pain
The Availability and Safety Study of Remimazolam Besylate for Injection on Sedation of ERAS Patients
This trial intends to evaluate Remimazolam Besylate's availability and safety compared with propofol.
- Trial name
- NCT04947345
- Testing
- Remimazolam Besylate, Propofol
- Volunteers
- 84 people
- Sponsor
- Peking Union Medical College Hospital
Low Back Pain
Assessment of Acupuncture to Improve Function, Exercise Capacity, and Pain
The purpose of this research proposal is to conduct a feasibility study to determine the viability a larger efficacy study of combined acupuncture treatments plus treadmill exercise to decrease pain, facilitate exercise, and…
- Trial name
- NCT00502619
- Testing
- Acupuncture, Treadmill Exercise
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- VA Maryland Health Care System
Breast Neoplasm Female, Pain, Postoperative
Effectiveness of Ultrasound Guided PECS Block on Opioid Consumption and Patient Satisfaction Through Adequate Pain Control Following Breast Cancer Surgery.
Breast cancer is the most common and leading cause of cancer deaths among females worldwide. Patients undergoing modified radical mastectomy (MRM) are associated with moderate to severe acute postoperative pain and shoulder…
- Conditions
- Breast Neoplasm Female, Pain, Postoperative, Pain, Analgesia
- Trial name
- NCT04343807
- Testing
- PECS Block, Control Group
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Pain Management, TKA
Photobiomodulation Therapy for Pain Control in Post-Operative Total Knee Arthroplasty Patients: A Pilot Study
A pilot study to assess the efficacy and feasibility of PBMT for pain control in patients undergoing a TKA and are discharged the same day from an ambulatory surgery center.
- Conditions
- Pain Management, TKA, Post Operative Analgesia, Low Level Laser Therapy
- Trial name
- NCT07750912
- Testing
- LightForce XLI
- Volunteers
- 15 people
- Sponsor
- Mohammad Burney, MD
Arthroplasty, Replacement, Knee, Pain, Postoperative
Comparison Of Femoral Block And Middle Adductor Canal Block In Patients With Knee Arthroplasty
Femoral and adductor nerve blocks with ultrasonography(USG) guidance are used effectively and efficiently in post-operative pain management in lower extremity surgical procedures.
- Conditions
- Arthroplasty, Replacement, Knee, Pain, Postoperative, Anesthesia and Analgesia, Anesthesia, Conduction
- Trial name
- NCT04768764
- Testing
- Ultrasound Guided Middle Adductor Canal Block, Ultrasound Guided Femoral Nerve Block., Bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Bozyaka Training and Research Hospital
Back Pain, Chronic Pain
Haloperidol for Pain Control in Patients With Acute Musculoskeletal Back Pain in the Emergency Department
Single center, double-blind, randomized, controlled trial in patients who present to the emergency department (ED) with a chief complaint of back pain.
- Trial name
- NCT06395428
- Testing
- Haloperidol, Ketorolac Tromethamine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Western Michigan University School of Medicine
Pain, Advanced Cancer
Sativex® for Relieving Persistent Pain in Participants With Advanced Cancer
This 9-week study aimed to determine the efficacy, safety and tolerability of nabiximols (Sativex®) as an adjunctive treatment, compared with placebo in relieving uncontrolled persistent chronic pain in participants with advanced…
- Trial name
- NCT01262651
- Testing
- Nabiximols
- Where
- 72 sites in United States, Belgium and 10 more
- Volunteers
- 397 people
- Sponsor
- GW Pharmaceuticals Ltd
Post-operative Pain, Gynecological Surgery
Acupuncture for Post-Operative Pain Control for Patients Undergoing Gynecological Surgery
This study investigates the role of acupuncture in controlling post-operative pain in patients who have undergone gynecological surgery.
- Conditions
- Post-operative Pain, Gynecological Surgery, Acupuncture
- Trial name
- NCT02855567
- Testing
- Acupuncture needles
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pain
Brain Response to Pain Control in People With Chronic Pain
Background: Researchers want to look at how the brain responds to painful stimulations. They also want to see if these responses are different in people with and without chronic pain.
- Trial name
- NCT01878019
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Cancer of Pancreas
Effects of Epidural Anesthesia and Analgesia on the Prognosis in Patients Undergoing Pancreatic Cancer Surgery
The purpose of this randomized controlled trial is to investigate the effects of epidural anesthesia and analgesia on the overall survival，disease-free survival and recovery in patients undergoing pancreatic cancer surgery.
- Trial name
- NCT03245346
- Testing
- GEA, PCEA, GA
- Where
- 2 sites in China
- Volunteers
- 540 people
- Sponsor
- Fudan University
Perioperative Analgesia, Hip Replacement, Total
Pericapsular Nerve Group Block Versus Intrathecal Morphine for Analgesia After Total Hip Arthroplasty
The Pericapsular Nerve Group (PENG) block is an effective method for postoperative pain management in patients undergoing primary total hip arthroplasty (THA) via a posterolateral approach.
- Conditions
- Perioperative Analgesia, Hip Replacement, Total, Postoperative Pain, Hip Disease
- Trial name
- NCT07449585
- Testing
- PNEG block, Spinal anesthesia with opioid, Spinal anesthesia without opioid
- Volunteers
- 180 people
- Sponsor
- Medical University of Gdansk
Pain, Postoperative, Osteoarthritis, Knee
Comparing Local Anesthetic Injections to Nerve Blocks for Pain Control After Total Knee Replacement
Why are we doing this study? People who have knee replacement surgery often feel pain afterward. Doctors use different methods to control this pain.
- Conditions
- Pain, Postoperative, Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
- Trial name
- LIA-PNB-TKA (NCT07744503)
- Testing
- Continuous Femoral and Sciatic Nerve Block (Ropivacaine), Local Infiltration Analgesia (Ropivacaine, Ketorolac, Epinephrine)
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Christopher Male
Lidocaine, Analgesia
Continuous Lidocaine Infusion Via Closed Chest Drainage Tube for Pain Control After Thoracoscopic Partial Lung Resection
The goal of this clinical trial is to learn about the effects on postoperative analgesia of continuous lidocaine infusion via closed chest drainage tube for patients undergoing thoracoscopic partial lung resection.
- Conditions
- Lidocaine, Analgesia, Pain, Postoperative, Thoracic Surgery
- Trial name
- NCT05901389
- Testing
- Lidocaine, Sufentanil
- Where
- China
- Volunteers
- 451 people
- Sponsor
- Qilu Hospital of Shandong University
Femoral Neck Fracture
Postoperative Pain Control After Hip Hemiarthroplasty: Intrathecal Morphine vs Periarticular Infiltration of Bupivacaine
Falls are a common problem in elderly people which they have to receive the operation. Hemiarthroplasty is one of the common orthopedics operations.
- Trial name
- NCT01219062
- Testing
- morphine, control, Bupivacaine
- Where
- 2 sites in Thailand
- Volunteers
- 10 people
- Sponsor
- Mahidol University
Bone Metastases, Radiotherapy Side Effect
A Prospective Randomized Trial of High Dose Versus Standard Dose Stereotactic Radiotherapy for Pain Control in Patients With Bone Metastases
In the present study, we will prospectively evaluate the pain response and treatment failure rate to determine the most favorable radiation dose in single fraction stereotactic radiotherapy using the modern highly conformal…
- Trial name
- NCT04063254
- Testing
- Stereotactic Radiotherapy
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Coronary Angiography
Effects of Stress Ball Use During Femoral Catheter Removal After Coronary Angiography
This study aimed to evaluate the effects of using a stress ball during femoral catheter removal on quality of recovery, patient comfort, and pain in adults undergoing coronary angiography.
- Trial name
- SB-FCR (NCT07889479)
- Testing
- Stress Ball Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Maltepe University
Pain, Postoperative, Opioid Use
Therapeutic Efficacy of Intravenous Lidocaine Infusion Compared With Epidural Analgesia for Postoperative Pain Control in Adult Patients Undergoing Major Abdominal Surgery: Non-Inferiority Clinical Trial
Major abdominal surgery continues is one of the most performed surgical procedures in the world, both electively and urgently. One of the main problems of this type of intervention is postoperative pain.
- Trial name
- NCT04017013
- Testing
- Epidural Analgesia, Lidocaine Infusion
- Where
- Colombia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Colorectal Cancer, Pain
Epidural Versus Patient-controlled Analgesia for Reduction in Long-term Mortality Following Colorectal Cancer Surgery
Colorectal cancer is one of the most common cancers in the industrialized world (12% of all cancers). In Sweden, 6000 new cases of colorectal cancer are reported each year, and almost half of these cases result in death.
- Conditions
- Colorectal Cancer, Pain, Other Complications
- Trial name
- EPICOL (NCT01318161)
- Testing
- Ropivacaine + opioid epidurally, Morphine
- Where
- 2 sites in Sweden
- Volunteers
- 221 people
- Sponsor
- Örebro University, Sweden
Satisfaction, Pain Management After Surgery
Post-c-section Pain Control Satisfaction with Erector Spinae Simple Block Vs Lateral Quadratus Lumborum Block
The study will compare the difference between the patient's satisfaction after Erector spinae plane block (ESP) and Quadratus Lumborum block lateral approach after caesarean section alone or as part of multimodal analgesia.
- Trial name
- NCT06771466
- Testing
- Bilateral Ultrasound-Guided Erector Spinae Plane Block (group E), Bilateral Ultrasound-guided Quadratus Lumborum, Lateral approach (group Q)
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Wael Sayed El Gharabawy
Pharmacological Action
Efficacy and Safety of Liposomal Bupivacaine Under ERAS Concept for Postoperative Analgesia of Ultrasound-Guided QLB in Gynecologic Laparoscopic Patients: A Randomized, Single-blind, Active-Controlled Clinical Study
With the development of the concept of comfortable medicine and enhanced recovery surgery (ERAS), optimizing the perioperative management of patients, reducing surgical stress, and reducing postoperative pain can effectively…
- Trial name
- NCT06288841
- Testing
- Ropivacaine injection, Bupivacaine liposome
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tianjin Medical University General Hospital