Clinical trials: Patient Reported Outcome (PRO)
Multiple Sclerosis
Acupressure in MS Patients
This study aims to evaluate the effects of acupressure therapy on patients with Multiple Sclerosis (MS). MS is a chronic autoimmune disease affecting the central nervous system, characterized by inflammation, demyelination, and…
- Trial name
- APEX-MS (NCT06755463)
- Testing
- Self-acupressure education
- Volunteers
- 82 people
- Sponsor
- Abant Izzet Baysal University
Breast Cancer
Comprehensive Patient Reported Outcomes (PRO) Management for Oncology Practice
Cancer symptoms due to disease progression or side effects caused by cancer treatment are prevalent. Most cancer patients are treated in outpatient settings.
- Trial name
- NCT01108315
- Testing
- Report symptoms via web or phone-based system
- Where
- 2 sites in United States
- Volunteers
- 138 people
- Sponsor
- BrightOutcome
Arthrosis
Changes in Physical Activity, Sleep and Knee Function After Same-Day Discharge Knee Arthroplasty
The goal of this observational study is to examine changes in physical activity, sleep quality, knee extension and flexion strength, knee range of motion, and patient-reported outcomes before and after same-day discharge knee…
- Trial name
- ORTOMOVE (NCT07840391)
- Testing
- Medial unicompartmental knee arthroplasty (UKA), Total knee arthroplasty (TKA)
- Where
- 2 sites in Finland
- Volunteers
- 120 people
- Sponsor
- Turku University Hospital
Traumatic Brain Injury, Traumatic Brain Injury | Patient
A Pilot Study of Home-Based Rhythmic Auditory Stimulation to Evaluate Mobility, Balance, and Patient-Reported Outcomes After Traumatic Brain Injury
The goal of this study is to learn whether a home-based rhythmic auditory stimulation (RAS) program using the MR-001 device can help improve walking, balance, and other health outcomes in adults with moderate to severe traumatic…
- Conditions
- Traumatic Brain Injury, Traumatic Brain Injury | Patient, TBI, TBI-Traumatic Brain Injury
- Trial name
- BEAT TBI (NCT07702513)
- Testing
- Home-Based Rhythmic Auditory Stimulation
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Craig Hospital
Breast Cancer
Preoperative Imaging in DIEP Flap Breast Reconstruction
The purpose of this study is to determine whether preoperative abdominal imaging using either CT angiogram (CTA), or MR angiogram (MRA) will impact perforator dissection time, cost, and patient outcomes in DIEP flap breast…
- Trial name
- NCT02111239
- Testing
- CTA, MRA
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Low Anterior Resection Syndrome
Translation of the International Consensus Definition of LARS Into a Bowl Dysfunction Severity Scoring Tool (New LARS Score)
The purpose of this study is to develop a new severity scoring tool for Low Anterior Resection Syndrome (LARS) drawing on the international consensus criteria for LARS as well as opinions of patients with lived-experience of LARS.
- Trial name
- NCT05605600
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- Cardiff and Vale University Health Board
Edentulism, Edentulism Complete
Masticatory Efficiency, Bite Force, and Patient-Reported Outcomes in Patients Rehabilitated With Complete and Partial Dentures Supported by Teeth, Mini-Implants, or Conventional Implants
This study aims to evaluate masticatory efficiency, bite force, and patient-reported outcomes in edentulous and partially edentulous patients rehabilitated with different removable prosthodontic treatment modalities.
- Conditions
- Edentulism, Edentulism Complete, Partial Edentulism, Complete Dentures
- Trial name
- IMPROSTREHAB (NCT07639112)
- Where
- 2 sites in Croatia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Huntington's Disease
FuRST 2.0 Cognitive Pre-Testing
The FuRST 2.0 scale is being developed as a Patient Reported Outcome (PRO) with information coming directly from the Huntington's Disease Gene Expansion Carrier (HDGEC) and companion through self-report.
- Trial name
- NCT02881931
- Testing
- FuRST 2.0
- Where
- 4 sites in United States, Canada
- Volunteers
- 75 people
- Sponsor
- CHDI Foundation, Inc.
Pleural Diseases, Pleural Mesothelioma
Prospective Data Collection on Clinical, Radiological and Patient Reported Outcomes After Pleural Intervention
The PROSPECT study aims to look at the number of problems or side effects which occur after patients have had a procedure completed to remove fluid or air from the space between the lung and the chest wall.
- Conditions
- Pleural Diseases, Pleural Mesothelioma, Pneumothorax, Pleural Effusion
- Trial name
- PROSPECT (NCT05910112)
- Testing
- Pleural interventions
- Where
- United Kingdom
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Cancer, Breast Cancer
The Care Tracker Study: Using Patient-Reported Data to Address Racial Disparity in Cancer Treatment
This study assesses the feasibility and acceptability of a brief electronic patient-reported outcome (ePRO) tool that allows patients to self-identify impending delays.
- Conditions
- Cancer, Breast Cancer, Colorectal Cancer
- Trial name
- NCT06096623
- Testing
- Weekly Survey
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Atopic Dermatitis
ASPIRE: PROs & Caregiver Burden in Children With Atopic Dermatitis
This is an open-label, randomized, cross-sectional study to monitor the effects of crisaborole and tacrolimus 0.03% on patient-reported outcomes and caregiver burden in children (ages 2 to 15 years, inclusive) with ≤ moderate…
- Trial name
- NCT03645057
- Testing
- Crisaborole, Tacrolimus 0.03% Ointment
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Rochester
Multiple Sclerosis
A Study to Provide Complementary Efficacy, Safety and Patient Reported Outcomes Data in Participants With Active Relapsing Forms of Multiple Sclerosis (MS) in a Pragmatic Setting
This national, open-label study is designed to give complementary efficacy, safety and patient reported outcomes (PROs) data in participants with active relapsing forms of MS.
- Trial name
- PRO-MSACTIVE (NCT03589105)
- Testing
- Ocrelizumab 300 mg, Ocrelizumab 600 mg
- Where
- 46 sites in France
- Volunteers
- 423 people
- Sponsor
- Hoffmann-La Roche
Total Knee Arthroplasty, Regional Anesthesia
Effects of 10 Versus 20 mL Local Anesthetic for Popliteal Plexus Block on Opioid Consumption, Pain, and Patient-Reported Outcomes After Total Knee Arthroplasty
This trial aims to assess the analgesic effect of Popliteal Plexus Block (PPB) with 10 mL versus 20 mL of Bupivacain 5 mg/mL, when applied as an adjunct treatment to a multimodal analgesic regimen following primary total knee…
- Conditions
- Total Knee Arthroplasty, Regional Anesthesia, Multimodal Analgesic Approach, Postoperative Opioid-related Complications
- Trial name
- NCT06908837
- Testing
- Bupivacaine
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Regionshospitalet Silkeborg
Neuroendocrine Tumors, Lung Neuroendocrine Neoplasm
Efficacy and Safety of Radiotherapy Compared to Everolimus in Somatostatin Receptor Positive Neuroendocrine Tumors of the Lung and Thymus.
LEVEL trial aims to demonstrate the higher efficacy of 177Lu-edotreotide over everolimus in patients with well to moderately differentiated neuroendocrine tumors of the lung and thymus who require systemic therapy.
- Conditions
- Neuroendocrine Tumors, Lung Neuroendocrine Neoplasm, Thymus Neoplasms
- Trial name
- LEVEL (NCT05918302)
- Testing
- 177Lu-edotreotide, Everolimus
- Where
- 27 sites in Belgium, France and 2 more
- Volunteers
- 170 people
- Sponsor
- Grupo Espanol de Tumores Neuroendocrinos
Vulvar Atrophy, Vulvovaginal Signs and Symptoms
Changes in the Impact of Genitourinary Syndrome of Menopause With a Novel Nonhormonal Vulvovaginal Gel Assessed by PROMs.
The goal of this clinical trial is to improve the management of Genitourinary syndrome of menopause (GSM) to preliminary assess safety and effectivity of a novel hormone-free mucosa composition (XCMIM20m) applied topically to the…
- Conditions
- Vulvar Atrophy, Vulvovaginal Signs and Symptoms, Genitourinary Syndrome of Menopause, Quality of Life
- Trial name
- STOPGSMP (NCT06962345)
- Testing
- Hormone-free vulvovaginal gel with the tested composition XCMIM20m
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Mucosa Innovations, S.L.
Solid Cancer
Randomized Phase II Study to Evaluate Efficacy of Web-based Patient-reported Outcome (PRO) Application in Solid Cancer Patients
This is a single-center, open-label, Phase 2 study to evaluate the feasibility of a mobile PRO and its efficacy in reducing unplanned healthcare utilization (unplanned outpatient visits, emergency department visits, and…
- Trial name
- Mobile PRO (NCT07301996)
- Testing
- Mobile PRO, usual care
- Where
- South Korea
- Volunteers
- 166 people
- Sponsor
- Asan Medical Center
Total Hip Arthroplasty
Cemented Acetabular Cups Clinical Study
This clinical study has the aim to evaluate clinical, radiographic, patient-reported outcomes of total hip arthroplasty with the implant of Mueller cemented acetabular cups up to 2 years after surgery, in order to assess the…
- Trial name
- NCT04831918
- Testing
- Mueller cemented cups
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Limacorporate S.p.a
Surgeons, Surgical Procedure, Unspecified
Improving Surgical Communication for Patients in Wisconsin
The purpose of this study is to evaluate a new training program to support communication between surgeons and their patients. The goal of the training program is to help patients get the information they need to make treatment…
- Trial name
- NCT06647303
- Testing
- Training on communication framework, Focus Group, Surveys
- Where
- United States
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Type 2 Diabetes Mellitus
A Study to Assess Insulin Delivery With PaQ® in Patients With Type 2 Diabetes Mellitus
The purpose of the study is to obtain an assessment (efficacy, safety, and patient reported outcomes) of basal bolus insulin delivery with PaQ in insulin-using patients with type 2 diabetes mellitus (T2DM).
- Trial name
- NCT02419859
- Testing
- PaQ® Insulin Delivery Device, Insulin, Asp(B28)-
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- CeQur Corporation
Severe Eosinophilic Asthma
Patient Reported Outcomes in Adults With Severe Eosinophilic Asthma on Benralizumab.
This study will generate patient reported outcomes (PROs) associated with the use of benralizumab as treatment for severe eosinophilic asthma.
- Trial name
- POWER (NCT03833141)
- Testing
- Survey Administration
- Where
- 20 sites in Canada
- Volunteers
- 170 people
- Sponsor
- AstraZeneca